Age-related decline in osteoblastogenesis and 1α-hydroxylase/CYP27B1 in human mesenchymal stem cells: Stimulation by parathyroid hormone

Aging Cell

Volumn 10, Issue 6, 2011, Pages 962-971

  Geng, Shuo ^a,b   Zhou, Shuanhu ^a   Glowacki, Julie ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b THE FIRST AFFILIATED HOSPITAL OF HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

CYP27B1; Marrow stromal cells; Mesenchymal stem cells; PTH; Signaling; Vitamin D

Indexed keywords

3 BROMO 5 TERT BUTYL 4 HYDROXYBENZYLIDENEMALONONITRILE; CALCIFEDIOL; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYTOCHROME P450 27B1; CYTOCHROME P450 ISOENZYME; KG 501; OXYGENASE; PARATHYROID HORMONE[1-34]; PROTEIN INHIBITOR; RECOMBINANT SOMATOMEDIN C; SMALL INTERFERING RNA; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; SOMATOMEDIN C RECEPTOR KINASE; UNCLASSIFIED DRUG;

ADULT; AGE DISTRIBUTION; AGED; AGING; ARTICLE; CELL MATURATION; CELL STIMULATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION; HORMONE ACTION; HUMAN; HUMAN CELL; KIDNEY CELL; MESENCHYMAL STEM CELL; OSTEOBLAST; OSTEOBLASTOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SYNTHESIS; TIME; UPREGULATION;

25-HYDROXYVITAMIN D3 1-ALPHA-HYDROXYLASE; ADULT; AGED; AGING; BLOTTING, WESTERN; CALCIFEDIOL; CELL DIFFERENTIATION; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; ENZYME INHIBITORS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; INSULIN-LIKE GROWTH FACTOR I; MESENCHYMAL STEM CELLS; NAPHTHOLS; OSTEOBLASTS; PARATHYROID HORMONE; PHOSPHORIC ACID ESTERS; POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; STEROID HYDROXYLASES; TYRPHOSTINS; VITAMIN D;

EID: 81155150024     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/j.1474-9726.2011.00735.x     Document Type: Article

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