Scutellarin attenuates human-neutrophil-elastase-induced mucus production by inhibiting the PKC-ERK signaling pathway in vitro and in vivo

American Journal of Chinese Medicine

Volumn 39, Issue 6, 2011, Pages 1193-1206

  Jiang, De Peng ^a   Li, Qi ^a   Yang, Jie ^a   Perelman, Juliy M ^b   Kolosov, Victor P ^b   Zhou, Xiang Dong ^a  

^a CHONGQING MEDICAL UNIVERSITY   (China)

^b Russian Academy of Medical Sciences   (Russian Federation)

Author keywords

Extracellular Signal Regulated Kinase 1 2; Human Neutrophil Elastase; MUC5AC; Protein Kinase C; Scutellarin

Indexed keywords

GEFITINIB; HUMAN NEUTROPHIL ELASTASE; LEUKOCYTE ELASTASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MUCIN 5AC; PROTEIN KINASE C; SCUTELLARIN; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL HYPERPLASIA; CHRONIC LUNG DISEASE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; GOBLET CELL; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATORY DISEASE; MALE; MUCUS HYPERSECRETION; MUCUS SECRETION; NONHUMAN; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALS; APIGENIN; CELL LINE; DRUGS, CHINESE HERBAL; ERIGERON; GLUCURONIC ACIDS; HUMANS; LEUKOCYTE ELASTASE; LUNG DISEASES, OBSTRUCTIVE; MALE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MUCIN 5AC; PROTEIN KINASE C; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION;

EID: 81155138944     PISSN: 0192415X     EISSN: None     Source Type: Journal    
DOI: 10.1142/S0192415X11009494     Document Type: Article

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