메뉴 건너뛰기




Volumn 70, Issue 3, 2008, Pages 845-852

Pulmonary delivery of scutellarin solution and mucoadhesive particles in rats

Author keywords

Flavonoids; Hyaluronan; Intratracheal spray; Intravenous delivery; Mucociliary transport; Peroral delivery; Pulmonary delivery; Scutellarin

Indexed keywords

EXCIPIENT; FLAVONOID; SCUTELLARIN; UNCLASSIFIED DRUG;

EID: 54949109737     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2008.07.004     Document Type: Article
Times cited : (42)

References (37)
  • 1
    • 34250334540 scopus 로고    scopus 로고
    • Advances of breviscapine in clinical applications and its side-effects
    • Wei N. Advances of breviscapine in clinical applications and its side-effects. China Pharm. 4 (2001) 144-146
    • (2001) China Pharm. , vol.4 , pp. 144-146
    • Wei, N.1
  • 2
    • 33746093547 scopus 로고    scopus 로고
    • Pharmacokinetics and metabolism of the flavonoid scutellarin in humans after a single oral administration
    • Chen X.Y., Cui L., Duan X.T., Ma B., and Zhong D.F. Pharmacokinetics and metabolism of the flavonoid scutellarin in humans after a single oral administration. Drug Metab. Dispos. 34 (2006) 1345-1352
    • (2006) Drug Metab. Dispos. , vol.34 , pp. 1345-1352
    • Chen, X.Y.1    Cui, L.2    Duan, X.T.3    Ma, B.4    Zhong, D.F.5
  • 3
    • 33646060748 scopus 로고    scopus 로고
    • Determination of scutellarin in mouse plasma and different tissues by high-performance liquid chromatography
    • Xiong F., Wang H., Cheng J., and Zhu J. Determination of scutellarin in mouse plasma and different tissues by high-performance liquid chromatography. J. Chromatogr. B 835 (2006) 114-118
    • (2006) J. Chromatogr. , vol.B 835 , pp. 114-118
    • Xiong, F.1    Wang, H.2    Cheng, J.3    Zhu, J.4
  • 4
    • 32644457579 scopus 로고    scopus 로고
    • Effect of breviscapine on ischemic cerebrovascular disease and its clinical investigation
    • He W., and Zeng F. Effect of breviscapine on ischemic cerebrovascular disease and its clinical investigation. Chin. J. Clin. Pharmacol. 18 (2002) 458-461
    • (2002) Chin. J. Clin. Pharmacol. , vol.18 , pp. 458-461
    • He, W.1    Zeng, F.2
  • 5
    • 1642424296 scopus 로고    scopus 로고
    • Protection against hydrogen peroxide-induced cytotoxicity in PC12 cells by scutellarin
    • Hong H., and Liu G.Q. Protection against hydrogen peroxide-induced cytotoxicity in PC12 cells by scutellarin. Life Sci. 74 (2004) 2959-2973
    • (2004) Life Sci. , vol.74 , pp. 2959-2973
    • Hong, H.1    Liu, G.Q.2
  • 6
    • 12344276329 scopus 로고    scopus 로고
    • Effect of scutellarin on nitric oxide production in early stages of neuron damage induced by hydrogen peroxide
    • Liu H., Yang X., Tang R., Liu J., and Xu H. Effect of scutellarin on nitric oxide production in early stages of neuron damage induced by hydrogen peroxide. Pharmacol. Res. 51 (2005) 205-210
    • (2005) Pharmacol. Res. , vol.51 , pp. 205-210
    • Liu, H.1    Yang, X.2    Tang, R.3    Liu, J.4    Xu, H.5
  • 7
    • 22044435005 scopus 로고    scopus 로고
    • Study on the role of hepatic first-pass elimination in the low oral bioavailability of scutellarin in rats
    • Hao X., Cheng G., Yu J., He Y., An F., and Sun J. Study on the role of hepatic first-pass elimination in the low oral bioavailability of scutellarin in rats. Pharmazie 60 (2005) 477-478
    • (2005) Pharmazie , vol.60 , pp. 477-478
    • Hao, X.1    Cheng, G.2    Yu, J.3    He, Y.4    An, F.5    Sun, J.6
  • 8
    • 26944439522 scopus 로고    scopus 로고
    • The lungs as a portal of entry for systemic drug delivery
    • Patton J.S., Fishburn C.S., and Weers J.G. The lungs as a portal of entry for systemic drug delivery. Proc. Am. Thorac. Soc. 1 (2004) 338-344
    • (2004) Proc. Am. Thorac. Soc. , vol.1 , pp. 338-344
    • Patton, J.S.1    Fishburn, C.S.2    Weers, J.G.3
  • 9
    • 0035719828 scopus 로고    scopus 로고
    • The lung as a route for systemic delivery of therapeutic proteins and peptides
    • Agu R.U., Ugwoke M.I., Armand M., Kinget R., and Verbeke N. The lung as a route for systemic delivery of therapeutic proteins and peptides. Respir. Res. 2 (2001) 198-209
    • (2001) Respir. Res. , vol.2 , pp. 198-209
    • Agu, R.U.1    Ugwoke, M.I.2    Armand, M.3    Kinget, R.4    Verbeke, N.5
  • 10
    • 33644627889 scopus 로고    scopus 로고
    • The expanding role of aerosols in systemic drug delivery gene therapy and vaccination
    • Laube B.L. The expanding role of aerosols in systemic drug delivery gene therapy and vaccination. Respir. Care 50 (2005) 1161-1174
    • (2005) Respir. Care , vol.50 , pp. 1161-1174
    • Laube, B.L.1
  • 11
    • 26944474854 scopus 로고    scopus 로고
    • Deposition of inhaled particles in the human respiratory tract and consequences for regional targeting in respiratory drug delivery
    • Heyder J. Deposition of inhaled particles in the human respiratory tract and consequences for regional targeting in respiratory drug delivery. Proc. Am. Thorac. Soc. 1 (2004) 315-320
    • (2004) Proc. Am. Thorac. Soc. , vol.1 , pp. 315-320
    • Heyder, J.1
  • 12
    • 0030663247 scopus 로고    scopus 로고
    • Airway deposition and clearance and systemic Pharmacokinetics of amiloride following aerosolization with an ultrasonic nebulizer to normal airways
    • Noone P.G., Regnis J.A., Liu X.R., Brouwer K.L.R., Robinson M., Edwards L., and Knowles M.R. Airway deposition and clearance and systemic Pharmacokinetics of amiloride following aerosolization with an ultrasonic nebulizer to normal airways. Chest 112 (1997) 1283-1290
    • (1997) Chest , vol.112 , pp. 1283-1290
    • Noone, P.G.1    Regnis, J.A.2    Liu, X.R.3    Brouwer, K.L.R.4    Robinson, M.5    Edwards, L.6    Knowles, M.R.7
  • 13
    • 32644435870 scopus 로고    scopus 로고
    • High lung deposition of 99mTc-labeled ciclesonide administered via HFA-MDI to patients with asthma
    • Newman S., Salmon A., Nave R., and Drollmann A. High lung deposition of 99mTc-labeled ciclesonide administered via HFA-MDI to patients with asthma. Respir. Med. 100 (2006) 375-384
    • (2006) Respir. Med. , vol.100 , pp. 375-384
    • Newman, S.1    Salmon, A.2    Nave, R.3    Drollmann, A.4
  • 14
    • 33646579180 scopus 로고    scopus 로고
    • Manipulation of beclomethasone-hydrofluoroalkane interactions using biocompatible macromolecules
    • Jones S.A., Martin G.P., and Brown M.B. Manipulation of beclomethasone-hydrofluoroalkane interactions using biocompatible macromolecules. J. Pharm. Sci. 95 (2006) 1060-1074
    • (2006) J. Pharm. Sci. , vol.95 , pp. 1060-1074
    • Jones, S.A.1    Martin, G.P.2    Brown, M.B.3
  • 15
    • 33748882339 scopus 로고    scopus 로고
    • Stabilisation of deoxyribonuclease in hydrofluoroalkanes using miscible vinyl polymers
    • Jones S.A., Martin G.P., and Brown M.B. Stabilisation of deoxyribonuclease in hydrofluoroalkanes using miscible vinyl polymers. J. Control. Release 115 (2006) 1-8
    • (2006) J. Control. Release , vol.115 , pp. 1-8
    • Jones, S.A.1    Martin, G.P.2    Brown, M.B.3
  • 16
    • 26444484541 scopus 로고    scopus 로고
    • The effects of polyvinyl alcohol on the in vitro stability and delivery of spray-dried protein particles from surfactant-free HFA 134a-based pressurised metered dose inhalers
    • Liao Y.H., Brown M.B., Jones S.A., Nazir T., and Martin G.P. The effects of polyvinyl alcohol on the in vitro stability and delivery of spray-dried protein particles from surfactant-free HFA 134a-based pressurised metered dose inhalers. Int. J. Pharm. 304 (2005) 29-39
    • (2005) Int. J. Pharm. , vol.304 , pp. 29-39
    • Liao, Y.H.1    Brown, M.B.2    Jones, S.A.3    Nazir, T.4    Martin, G.P.5
  • 17
    • 0034658305 scopus 로고    scopus 로고
    • Preparation and evaluation of the in vitro drug release properties and mucoadhesion of novel microspheres of hyaluronic acid and chitosan
    • Lim S.T., Martin G.P., Berry D.J., and Brown M.B. Preparation and evaluation of the in vitro drug release properties and mucoadhesion of novel microspheres of hyaluronic acid and chitosan. J. Control. Release 66 (2000) 281-292
    • (2000) J. Control. Release , vol.66 , pp. 281-292
    • Lim, S.T.1    Martin, G.P.2    Berry, D.J.3    Brown, M.B.4
  • 18
    • 14844317357 scopus 로고    scopus 로고
    • Difference in absorption of the two structurally similar flavonoid glycosides hyperoside and isoquercitrin in rats
    • Chang Q., Zuo Z., Chow M.S.S., and Ho W.K.K. Difference in absorption of the two structurally similar flavonoid glycosides hyperoside and isoquercitrin in rats. Eur. J. Pharm. Biopharm. 59 (2005) 549-555
    • (2005) Eur. J. Pharm. Biopharm. , vol.59 , pp. 549-555
    • Chang, Q.1    Zuo, Z.2    Chow, M.S.S.3    Ho, W.K.K.4
  • 20
    • 23044482912 scopus 로고    scopus 로고
    • Pharmacokinetics of breviscapine and its (-cyclodextrin complex in rats
    • Zhang H.Y., Ping Q.N., Guo J.X., and Cao F. Pharmacokinetics of breviscapine and its (-cyclodextrin complex in rats. Acta Pharm. Sinica 40 (2005) 563-567
    • (2005) Acta Pharm. Sinica , vol.40 , pp. 563-567
    • Zhang, H.Y.1    Ping, Q.N.2    Guo, J.X.3    Cao, F.4
  • 21
    • 42049094490 scopus 로고    scopus 로고
    • Pharmaceutical particle engineering via spray drying
    • Vehring R. Pharmaceutical particle engineering via spray drying. Pharm. Res. 25 (2008) 999-1022
    • (2008) Pharm. Res. , vol.25 , pp. 999-1022
    • Vehring, R.1
  • 23
    • 0035834272 scopus 로고    scopus 로고
    • Enhanced pulmonary absorption following aerosol administration of mucoadhesive powder microspheres
    • Sakagami M., Sakon K., Kinoshita W., and Makino Y. Enhanced pulmonary absorption following aerosol administration of mucoadhesive powder microspheres. J. Control. Release 77 (2001) 117-129
    • (2001) J. Control. Release , vol.77 , pp. 117-129
    • Sakagami, M.1    Sakon, K.2    Kinoshita, W.3    Makino, Y.4
  • 24
    • 0037161325 scopus 로고    scopus 로고
    • Mucoadhesive beclomethasone microspheres for powder inhalation: their pharmacokinetics and pharmacodynamics evaluation
    • Sakagami M., Kinoshita W., Sakon K., Sato J., and Makino Y. Mucoadhesive beclomethasone microspheres for powder inhalation: their pharmacokinetics and pharmacodynamics evaluation. J. Control. Release 80 (2002) 207-218
    • (2002) J. Control. Release , vol.80 , pp. 207-218
    • Sakagami, M.1    Kinoshita, W.2    Sakon, K.3    Sato, J.4    Makino, Y.5
  • 25
    • 30444452988 scopus 로고    scopus 로고
    • Regional lung deposition and bronchodilator response as a function of (2-agonist particle size
    • Usmani O.S., Biddiscombe M.F., and Barnes P.J. Regional lung deposition and bronchodilator response as a function of (2-agonist particle size. Am. J. Respir. Crit. Care Med. 172 (2005) 1497-1504
    • (2005) Am. J. Respir. Crit. Care Med. , vol.172 , pp. 1497-1504
    • Usmani, O.S.1    Biddiscombe, M.F.2    Barnes, P.J.3
  • 27
    • 29244456136 scopus 로고    scopus 로고
    • Enhancement of bronchial octreotide absorption by chitosan and N-trimethyl chitosan shows linear in vitro/in vivo correlation
    • Florea B.I., Thanou M., Junginger H.E., and Borchard G. Enhancement of bronchial octreotide absorption by chitosan and N-trimethyl chitosan shows linear in vitro/in vivo correlation. J. Control. Release 110 (2006) 353-361
    • (2006) J. Control. Release , vol.110 , pp. 353-361
    • Florea, B.I.1    Thanou, M.2    Junginger, H.E.3    Borchard, G.4
  • 28
    • 0037458930 scopus 로고    scopus 로고
    • Drug transport and metabolism characteristics of the human airway epithelial cell line Calu-3
    • Florea B.I., Cassara M.L., Junginger H.E., and Borchard G. Drug transport and metabolism characteristics of the human airway epithelial cell line Calu-3. J. Control. Release 87 (2003) 131-138
    • (2003) J. Control. Release , vol.87 , pp. 131-138
    • Florea, B.I.1    Cassara, M.L.2    Junginger, H.E.3    Borchard, G.4
  • 29
    • 20444378183 scopus 로고    scopus 로고
    • Human respiratory epithelial cell culture for drug delivery applications
    • Forbes B., and Ehrhardt C. Human respiratory epithelial cell culture for drug delivery applications. Eur. J. Pharm. Biopharm. 60 (2005) 193-205
    • (2005) Eur. J. Pharm. Biopharm. , vol.60 , pp. 193-205
    • Forbes, B.1    Ehrhardt, C.2
  • 30
    • 11844282711 scopus 로고    scopus 로고
    • Surface-modified PLGA nanosphere with chitosan improved pulmonary delivery of calcitonin by mucoadhesion and opening of the intercellular tight junctions
    • Yamamoto H., Kuno Y., Sugimoto S., Takeuchi H., and Kawashima Y. Surface-modified PLGA nanosphere with chitosan improved pulmonary delivery of calcitonin by mucoadhesion and opening of the intercellular tight junctions. J. Control. Release 102 (2005) 373-381
    • (2005) J. Control. Release , vol.102 , pp. 373-381
    • Yamamoto, H.1    Kuno, Y.2    Sugimoto, S.3    Takeuchi, H.4    Kawashima, Y.5
  • 31
    • 37849051886 scopus 로고    scopus 로고
    • Preparation and physicochemical characterization of supercritically dried insulin-loaded microparticles for pulmonary delivery
    • Amidi M., Pellikaan H.C., de Boer A.H., Crommelin D.J.A., Hennink W.E., and Jiskoot W. Preparation and physicochemical characterization of supercritically dried insulin-loaded microparticles for pulmonary delivery. Eur. J. Pharm. Biopharm. 68 (2008) 191-200
    • (2008) Eur. J. Pharm. Biopharm. , vol.68 , pp. 191-200
    • Amidi, M.1    Pellikaan, H.C.2    de Boer, A.H.3    Crommelin, D.J.A.4    Hennink, W.E.5    Jiskoot, W.6
  • 32
    • 0035016017 scopus 로고    scopus 로고
    • Effects of low-viscosity sodium hyaluronate preparation on the pulmonary absorption of rh-insulin in rats
    • Morimoto K., Metsugi K., Katsumata H., Iwanaga K., and Kakemi M. Effects of low-viscosity sodium hyaluronate preparation on the pulmonary absorption of rh-insulin in rats. Drug Dev. Ind. Pharm. 27 (2001) 365-371
    • (2001) Drug Dev. Ind. Pharm. , vol.27 , pp. 365-371
    • Morimoto, K.1    Metsugi, K.2    Katsumata, H.3    Iwanaga, K.4    Kakemi, M.5
  • 33
    • 0042074074 scopus 로고    scopus 로고
    • Sustained release of insulin from sodium hyaluronate based dry powder formulations after pulmonary delivery to beagle dogs
    • Surendrakumar K., Martyn G.P., Hodgers E.C.M., Jansen M., and Blair J.A. Sustained release of insulin from sodium hyaluronate based dry powder formulations after pulmonary delivery to beagle dogs. J. Control. Release 91 (2003) 385-394
    • (2003) J. Control. Release , vol.91 , pp. 385-394
    • Surendrakumar, K.1    Martyn, G.P.2    Hodgers, E.C.M.3    Jansen, M.4    Blair, J.A.5
  • 34
    • 54949154583 scopus 로고    scopus 로고
    • A. Quader, Spray Dried Formulations for the Pulmonary Delivery of Peptides and Proteins. Ph.D. Thesis, University of London, 2004.
    • A. Quader, Spray Dried Formulations for the Pulmonary Delivery of Peptides and Proteins. Ph.D. Thesis, University of London, 2004.
  • 35
  • 36
    • 0021792862 scopus 로고
    • Comparative deposition of inhaled aerosols in experimental animals and humans: a review
    • Schlesinger R.B. Comparative deposition of inhaled aerosols in experimental animals and humans: a review. J. Toxicol. Environ. Health 15 (1985) 197-214
    • (1985) J. Toxicol. Environ. Health , vol.15 , pp. 197-214
    • Schlesinger, R.B.1
  • 37
    • 26644454810 scopus 로고    scopus 로고
    • The basics and underlying mechanisms of mucoadhesion
    • Smart J.D. The basics and underlying mechanisms of mucoadhesion. Adv. Drug Deliv. Rev. 57 (2005) 1556-1568
    • (2005) Adv. Drug Deliv. Rev. , vol.57 , pp. 1556-1568
    • Smart, J.D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.