Perinatal vitamin D deficiency and childhood asthma: A molecular perspective

Current Respiratory Medicine Reviews

Volumn 7, Issue 6, 2011, Pages 404-407

  Rehan, Virender K ^a   Torday, John S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Asthma; Epithelial mesenchymal interactions; PPAR ; Pregnancy; PTHrP; Vitamin d; Wnt signaling

Indexed keywords

ADIPOPHILIN; CATHELICIDIN; DEFENSIN; LUNG SURFACTANT; VITAMIN D; VITAMIN D RECEPTOR;

APOPTOSIS; ASTHMA; BRONCHUS MUCOSA; CELL PROLIFERATION; CHILDHOOD DISEASE; FIBROBLAST; HUMAN; HYDROXYLATION; LUNG DEVELOPMENT; MYOFIBROBLAST; NUTRITIONAL STATUS; PARACRINE SIGNALING; PHOSPHOLIPID SYNTHESIS; PREGNANCY; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; VITAMIN D DEFICIENCY; VITAMIN SUPPLEMENTATION;

EID: 81155126281     PISSN: 1573398X     EISSN: 18756387     Source Type: Journal    
DOI: 10.2174/157339811798072621     Document Type: Review

References (46)

1. World health organization. Asthma- Fact sheet N°307.
2. National Heart, Lung and Blood Institute Chartbook on cardiovascular, lung and blood diseases, U.S. Department of Health and Human Services, National Institute of Health 2007.
3. Hollis BW, Wagner CL. Vitamin D deficiency during pregnancy: an ongoing epidemic. Am J Clin Nutr 2006; 84: 273.
4. Lee JM, Smith JR, Philipp BL, Chen TC, Mathieu J, Holick MF. Vitamin D deficiency in a healthy group of mothers and newborn infants. Clin Pediatr (Phila) 2007; 46: 42-44.
5. Bassir M, Laborie S, Lapillonne A, Claris O, Chappuis MC, Salle BL. Vitamin D deficiency in Iranian mothers and their neonates: a pilot study. Acta Pediatr 2001; 90: 577-579.
6. Sachan A, Gupta R, Das V, Agarwal A, Awasthi PK, Bhatia V. High prevalence of vitamin D deficiency among pregnant women and their newborns in northern India. Am J Clin Nutr 2005; 81: 1060-1064.
7. Judkins A, Eagleton C. Vitamin D deficiency in pregnant New Zealand women. N Z Med J 2006;119: U2144.
8. Van der Meer IM, Karamali NS, Boeke AJ, et al. High prevalence of vitamin D deficiency in pregnant non-Western women in The Hague, Netherlands. Am J Clin Nutr 2006; 84: 350-353.
9. Devereux G, Litonjua AA, Turner SW, et al. Maternal vitamin D intake during pregnancy and early childhood wheezing. Am J Clin Nutr 2007; 85(3): 853-859.
10. Litonjua AA, Weiss ST. Is vitamin D deficiency to blame for the asthma epidemic? J Allergy Clin Immunol 2007; 120(5): 1031-1035.
11. Camargo CA Jr, Rifas-Shiman SL, Litonjua AA, et al. Maternal intake of vitamin D during pregnancy and risk of recurrent wheeze in children at 3 yrs of age. Am J Clin Nutr 2007; 85(3): 788-795.
12. Black PN, Scragg RS. Relationship between serum 25 hydroxyvitamin D and pulmonary function in the third national health and nutrition examination survey. Chest 2005; 128(6): 3792-3798.
13. Witte A, Weaver C, Mahon BD, August A, Cantorna MT. Vitamin- D receptor-deficient mice fail to develop experimental allergic asthma. J Immunol 2004; 173: 3432-3436.
14. Topilski I, Flaishon L, Naveh Y, Harmelin A, Levo Y, Shachar I. The anti-inflammatory effects of 1,25-dihydroxyvitamin D3 on Th2 cells in vivo are due in part to the control of integrin-mediated T lymphocyte homing. Eur J Immunol 2004; 34(4): 1068-1076.
15. Elias JA, Zhu Z, Chupp G, Homer RJ. Airway remodeling in asthma. J Clin Invest 1999; 104: 1001-1006.
16. Woodruff PG, Dolganov GM, Ferrando RE, et al. Hyperplasia of smooth muscle in mild to moderate asthma without changes in cell size or gene expression. Am J Respir Crit Care Med 2004; 169: 1001-1006.
17. Cossu G, Tajbakhsh S, Buckingham M. How is myogenesis initiated in the embryo? Trends Genet 1996; 12: 218-223.
18. Ross SE, Hemati N, Longo KA, et al. Inhibition of adipogenesis by Wnt signaling. Science 2000; 289: 950-953.
19. Gosens R, Roscioni, SS, Bart GJ, et al. Pharmacology of airway smooth muscle proliferation. Eur J Pharmacol 2008; 585(2/3): 385-397.
20. Marie Demay. Muscle: A nontraditional 1,25-Dihydroxyvitamin D target tissue exhibiting classic hormone-dependent vitamin D receptor actions. Endocrinology 2003; 144(12): 5135-5137.
21. Holgate ST. Asthma: more than an inflammatory disease. Curr Opin Allergy Clin Immunol 2002; 2: 27-29.
22. Torday JS, Rehan VK. A paracrine model for lung development, disease, and treatment-perspective. Pediatr Res 2007; 62(1): 2-7.
23. Awonusonu F, Srinivasan S, Strange J, Al-Jumaily W, Bruce MC. Developmental shift in the relative percentages of lung fibroblast subsets: role of apoptosis postseptation. Am J Physiol 1999; 277(4 Pt 1): L848-L859.
24. Sakurai R, Shin E, Fonseca S, et al. 1alpha,25(OH)2D3 and its 3- epimer promote rat lung alveolar epithelial-mesenchymal interactions and inhibit lipofibroblast apoptosis. Am J Physiol Lung Cell Mol Physiol 2009; 297(3): L496-L505.
25. Lee K, Deeds JD, Segre GV. Expression of parathyroid hormonerelated peptide and its receptor messenger ribonucleic acids during fetal development of rats. Endocrinol 1995; 136: 453-463.
26. Rubin LP, Kovacs CS, De Paepe ME, Tsai SW, Torday JS, Kronenberg HM. Arrested pulmonary alveolar cytodifferentiation and defective surfactant synthesis in mice missing the gene for parathyroid hormone-related protein. Dev Dyn 2004; 230: 278-89.
27. Kovala T, Lorimer IA, Brickenden AM, Ball EH, Sanwal BD. Protein kinase A regulation of cAMP phosphodiesterase expression in rat skeletal myoblasts. J Biol Chem 1994; 269: 8680-8685.
28. Ross SE, Hemati N, Longo KA, et al. Inhibition of adipogenesis by Wnt signaling. Science 2000; 289: 950-953.
29. Tontonoz P, Hu E, Spiegelman BM. Regulation of adipocyte gene expression and differentiation by peroxisome proliferator activated receptor gamma. Curr Opin Genet Dev 1995; 5: 571-576.
30. Schultz CJ, Torres E, Londos C, Torday JS. Role of adipocyte differentiation-related protein in surfactant phospholipid synthesis by type II cells. Am J Physiol Lung Cell Mol Physiol 2002; 283: L288-L296.
31. Torday JS, Sun H, Wang L, Torres E, Sunday ME, Rubin LP. Leptin mediates the parathyroid hormone-related protein paracrine stimulation of fetal lung maturation. Am J Physiol Lung Cell Mol Physiol 2002; 282(3): L405-L410.
32. Torday JS, Rehan VK. Stretch-stimulated surfactant synthesis is coordinated by the paracrine actions of PTHrP and leptin. Am J Physiol Lung Cell Mol Physiol 2002; 283(1): L130-135.
33. Torday JS, Rehan VK. Up-regulation of fetal rat lung parathyroid hormone-related protein gene regulatory network down-regulates the Sonic Hedgehog/Wnt/beta catenin gene regulatory network. Pediatr Res 2006; 60: 382-388.
34. Cullen A, Emanuel RL, Torday JS, Asokananthan N, Sikorski KA, Sunday ME. Bombesin-like peptide and receptors in lung injury models: diverse gene expression, similar function. Peptides 2000; 21: 1627-1638.
35. Sharma S, Tantisira K, Carey V, et al. A role for Wnt signaling genes in the pathogenesis of impaired lung function in asthma. Am J Respir Crit Care Med 2010; 181(4): 328-336.
36. Torday JS, Rehan VK. Exploiting cellular-developmental evolution as the scientific basis for the preventive medicine. Med hypothesis 2009; 72(5): 596-602.
37. Sundh H, Larsson D, Sundell K. Environmental salinity regulates the in vitro production of [3H]-1,25-dihydroxyvitamin D3 and [3H]-24,25 dihydroxyvitamin D3 in rainbow trout (Oncorhynchus mykiss). Gen Comp Endocrinol 2007; 152(2/3): 252-258.
38. Rehan VK, Dargan-Batra SK, Wang Y, et al. A paradoxical temporal response of the PTHrP/PPARgamma signaling pathway to lipopolysaccharide in an in vitro model of the developing rat lung. Am J Physiol Lung Cell Mol Physiol 2007; 293(1): L182-L190.
39. Gibson G. Decanalization and the origin of complex disease. Nat Rev Genet 2009; 10(2): 134-140.
40. Waddington CH. Canalization of development and the inheritance of acquired characters. Nature 1942; 150: 563-565.
41. Hansdottir S, Monick MM, Hinde SL, Lovan N, Look DC, Hunninghake GW. Respiratory epithelial cells convert inactive vitamin D to its active form: potential effects on host defense. J Immunol 2008; 181(10): 7090-7099.
42. Ong PY, Hamid QA, Travers JB, et al. Decreased IL-15 may contribute to elevated IgE and acute inflammation in atopic dermatitis. J Immunol 2002; 168(1): 505-510.
43. Lange NE, Litonjua A, Hawrylowicz CM, Weiss S. Vitamin D, the immune system and asthma. Expert Rev Clin Immunol 2009; 5(6): 693-702.
44. Ginde AA, Mansbach JM, Camargo CA. Vitamin D, respiratory infections, and asthma. Curr Allergy Asthma Rep 2009; 9: 81-87.
45. Topilski I, Flaishon L, Naveh Y, Harmelin A, Levo Y, Shachar I. The anti-inflammatory effects of 1,25-dihydroxyvitamin D3 on Th2 cells in vivo are due in part to the control of integrin-mediated T lymphocyte homing. Eur J Immunol 2004; 34(4): 1068-1076.
46. Matheu V, Back O, Mondoc E, Issazadeh-Navikas S. Dual effects of vitamin D-induced alteration of TH1/TH2 cytokine expression: enhancing IgE production and decreasing airway eosinophilia in murine allergic airway disease. J Allergy Clin Immunol 2003; 112: 585-559.