메뉴 건너뛰기




Volumn 12, Issue , 2011, Pages

Tyrosine phosphorylation of cortactin by the FAK-Src complex at focal adhesions regulates cell motility

Author keywords

Cell motility; Cortactin; Cortactin tyrosine phosphorylation; Fak; Fak src complex; Focal adhesions

Indexed keywords

CORTACTIN; F ACTIN; FOCAL ADHESION KINASE; PROLINE; PROTEIN SH3; PROTEIN TYROSINE KINASE; FOCAL ADHESION KINASE 1; TYROSINE;

EID: 81055148345     PISSN: None     EISSN: 14712121     Source Type: Journal    
DOI: 10.1186/1471-2121-12-49     Document Type: Article
Times cited : (55)

References (43)
  • 1
    • 75749103348 scopus 로고    scopus 로고
    • Src signaling in cancer invasion
    • Guarino M. Src signaling in cancer invasion. J Cell Physiol 2010, 223:14-26.
    • (2010) J Cell Physiol , vol.223 , pp. 14-26
    • Guarino, M.1
  • 2
    • 0031439247 scopus 로고    scopus 로고
    • Cellular functions regulated by Src family kinases
    • 10.1146/annurev.cellbio.13.1.513, 9442882
    • Thomas SM, Brugge JS. Cellular functions regulated by Src family kinases. Annu Rev Cell Dev Biol 1997, 13:513-609. 10.1146/annurev.cellbio.13.1.513, 9442882.
    • (1997) Annu Rev Cell Dev Biol , vol.13 , pp. 513-609
    • Thomas, S.M.1    Brugge, J.S.2
  • 3
    • 2942618768 scopus 로고    scopus 로고
    • A renaissance for Src
    • Yeatman TJ. A renaissance for Src. Nat Rev Cancer 2004, 4:407-480.
    • (2004) Nat Rev Cancer , vol.4 , pp. 407-480
    • Yeatman, T.J.1
  • 4
    • 0038386613 scopus 로고    scopus 로고
    • Src family kinases in tumor progression and metastasis
    • 10.1023/A:1023772912750, 12884910
    • Summy JM, Gallick GE. Src family kinases in tumor progression and metastasis. Cancer Metastasis Rev 2003, 22:337-358. 10.1023/A:1023772912750, 12884910.
    • (2003) Cancer Metastasis Rev , vol.22 , pp. 337-358
    • Summy, J.M.1    Gallick, G.E.2
  • 5
    • 34047265691 scopus 로고    scopus 로고
    • Dasatinib inhibits migration and invasion in diverse human sarcoma cell lines and induces apoptosis in bone sarcoma cells dependent on Src kinase for survival
    • 10.1158/0008-5472.CAN-06-3469, 17363602
    • Shor AC, Keschman EA, Lee FY, Muro-Cacho C, Letson GD, Trent JC, Pledger WJ, Jove R. Dasatinib inhibits migration and invasion in diverse human sarcoma cell lines and induces apoptosis in bone sarcoma cells dependent on Src kinase for survival. Cancer Res 2007, 67:2800-2808. 10.1158/0008-5472.CAN-06-3469, 17363602.
    • (2007) Cancer Res , vol.67 , pp. 2800-2808
    • Shor, A.C.1    Keschman, E.A.2    Lee, F.Y.3    Muro-Cacho, C.4    Letson, G.D.5    Trent, J.C.6    Pledger, W.J.7    Jove, R.8
  • 6
    • 0025376378 scopus 로고
    • Monoclonal antibodies to individual tyrosine-phosphorylated protein substrates of oncogene-encoded tyrosine kinases
    • 10.1073/pnas.87.9.3328, 53893, 2110361
    • Kanner SB, Reynolds AB, Vines RR, Parsons JT. Monoclonal antibodies to individual tyrosine-phosphorylated protein substrates of oncogene-encoded tyrosine kinases. Proc Natl Acad Sci USA 1990, 87:3328-3332. 10.1073/pnas.87.9.3328, 53893, 2110361.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 3328-3332
    • Kanner, S.B.1    Reynolds, A.B.2    Vines, R.R.3    Parsons, J.T.4
  • 7
    • 0025940103 scopus 로고
    • Identification and characterization of a novel cytoskeleton-associated pp60src substrate
    • 361526, 1922035
    • Wu H, Reynolds AB, Kanner SB, Vines RR, Parsons JT. Identification and characterization of a novel cytoskeleton-associated pp60src substrate. Mol Cell Biol 1991, 11:5113-5124. 361526, 1922035.
    • (1991) Mol Cell Biol , vol.11 , pp. 5113-5124
    • Wu, H.1    Reynolds, A.B.2    Kanner, S.B.3    Vines, R.R.4    Parsons, J.T.5
  • 8
    • 0032476012 scopus 로고    scopus 로고
    • The role of tyorsine phosphorylation of cortactin in the locomotion of endothelial cells
    • 10.1074/jbc.273.40.25770, 9748248
    • Huang C, Liu J, Haudenschild CC, Zhan X. The role of tyorsine phosphorylation of cortactin in the locomotion of endothelial cells. J Biol Chem 1998, 273:25770-25776. 10.1074/jbc.273.40.25770, 9748248.
    • (1998) J Biol Chem , vol.273 , pp. 25770-25776
    • Huang, C.1    Liu, J.2    Haudenschild, C.C.3    Zhan, X.4
  • 10
    • 0035475450 scopus 로고    scopus 로고
    • Cortactin: coupling membrane dynamics to cortical actin assembly
    • 10.1038/sj.onc.1204783, 11607842
    • Weed SA, Parsons JT. Cortactin: coupling membrane dynamics to cortical actin assembly. Oncogene 2001, 20:6418-6434. 10.1038/sj.onc.1204783, 11607842.
    • (2001) Oncogene , vol.20 , pp. 6418-6434
    • Weed, S.A.1    Parsons, J.T.2
  • 11
    • 22744434624 scopus 로고    scopus 로고
    • Cortactin promotes cell motility by enhancing lamellipodial persistence
    • 10.1016/j.cub.2005.06.043, 16051170
    • Bryce NS, Clark ES, Leysath JL, Currie JD, Webb DJ, Weaver AM. Cortactin promotes cell motility by enhancing lamellipodial persistence. Curr Biol 2005, 15:1276-1285. 10.1016/j.cub.2005.06.043, 16051170.
    • (2005) Curr Biol , vol.15 , pp. 1276-1285
    • Bryce, N.S.1    Clark, E.S.2    Leysath, J.L.3    Currie, J.D.4    Webb, D.J.5    Weaver, A.M.6
  • 13
    • 33646156176 scopus 로고    scopus 로고
    • Cortactin affects cell migration by regulating intercellular adhesion and cell spreading
    • 10.1016/j.yexcr.2006.01.033, 16527272
    • van Rossum AG, Moolenaar WH, Schuuring E. Cortactin affects cell migration by regulating intercellular adhesion and cell spreading. Exp Cell Res 2006, 312:1658-1670. 10.1016/j.yexcr.2006.01.033, 16527272.
    • (2006) Exp Cell Res , vol.312 , pp. 1658-1670
    • van Rossum, A.G.1    Moolenaar, W.H.2    Schuuring, E.3
  • 14
    • 0028981376 scopus 로고
    • Tyrosine phosphorylation of p130Cas and cortactin accompanies integrin-mediated cell adhesion to extracellular matrix
    • 10.1074/jbc.270.38.22259, 7545676
    • Vuori K, Ruoslahti E. Tyrosine phosphorylation of p130Cas and cortactin accompanies integrin-mediated cell adhesion to extracellular matrix. J Biol Chem 1995, 270:22259-22262. 10.1074/jbc.270.38.22259, 7545676.
    • (1995) J Biol Chem , vol.270 , pp. 22259-22262
    • Vuori, K.1    Ruoslahti, E.2
  • 16
    • 42049103661 scopus 로고    scopus 로고
    • Hyperphosphorylated cortactin in cancer cells plays an inhibitory role in cell motility
    • 10.1158/1541-7786.MCR-07-0220, 18403644
    • Jia L, Uekita T, Sakai R. Hyperphosphorylated cortactin in cancer cells plays an inhibitory role in cell motility. Mol Cancer Res 2008, 6:654-662. 10.1158/1541-7786.MCR-07-0220, 18403644.
    • (2008) Mol Cancer Res , vol.6 , pp. 654-662
    • Jia, L.1    Uekita, T.2    Sakai, R.3
  • 17
    • 0027419589 scopus 로고
    • Cortactin, an 80/85-kilodalton pp60Src substrate, is a filamentous actin-binding protein enriched in the cell cortex
    • 10.1083/jcb.120.6.1417, 2119758, 7680654
    • Wu H, Parsons JT. Cortactin, an 80/85-kilodalton pp60Src substrate, is a filamentous actin-binding protein enriched in the cell cortex. J Cell Biol 1993, 120:1417-1426. 10.1083/jcb.120.6.1417, 2119758, 7680654.
    • (1993) J Cell Biol , vol.120 , pp. 1417-1426
    • Wu, H.1    Parsons, J.T.2
  • 18
    • 0035814938 scopus 로고    scopus 로고
    • Cortactin promotes and stabilizes Arp2/3-induced actin filament network formation
    • 10.1016/S0960-9822(01)00098-7, 11267876
    • Weaver AM, Karginov AV, Kinley AW, Weed SA, Li Y, Parsons JT, Cooper JA. Cortactin promotes and stabilizes Arp2/3-induced actin filament network formation. Curr Biol 2001, 11:370-374. 10.1016/S0960-9822(01)00098-7, 11267876.
    • (2001) Curr Biol , vol.11 , pp. 370-374
    • Weaver, A.M.1    Karginov, A.V.2    Kinley, A.W.3    Weed, S.A.4    Li, Y.5    Parsons, J.T.6    Cooper, J.A.7
  • 19
    • 4344674527 scopus 로고    scopus 로고
    • Cortactin signaling and dynamic actin networks
    • 1133910, 15186216
    • Daly RJ. Cortactin signaling and dynamic actin networks. Biochem J 2004, 382:13-25. 1133910, 15186216.
    • (2004) Biochem J , vol.382 , pp. 13-25
    • Daly, R.J.1
  • 20
    • 0141533044 scopus 로고    scopus 로고
    • Integrin signaling to the actin cytoskeleton
    • 10.1016/S0955-0674(03)00109-1, 14519392
    • DeMali KA, Wennerberg K, Burridge K. Integrin signaling to the actin cytoskeleton. Curr Opin Cell Biol 2003, 15:572-582. 10.1016/S0955-0674(03)00109-1, 14519392.
    • (2003) Curr Opin Cell Biol , vol.15 , pp. 572-582
    • DeMali, K.A.1    Wennerberg, K.2    Burridge, K.3
  • 21
    • 0036441523 scopus 로고    scopus 로고
    • Cellular control of actin nucleation
    • 10.1146/annurev.cellbio.18.040202.112133, 12142287
    • Welch MD, Mullins RD. Cellular control of actin nucleation. Annu Rev Cell Dev Biol 2002, 18:247-288. 10.1146/annurev.cellbio.18.040202.112133, 12142287.
    • (2002) Annu Rev Cell Dev Biol , vol.18 , pp. 247-288
    • Welch, M.D.1    Mullins, R.D.2
  • 22
    • 0037904987 scopus 로고    scopus 로고
    • The integrin-actin connection, an enternal love affair
    • 10.1093/emboj/cdg245, 156003, 12743027
    • Brakebusch C, Fassler R. The integrin-actin connection, an enternal love affair. EMBO J 2003, 22:2324-2333. 10.1093/emboj/cdg245, 156003, 12743027.
    • (2003) EMBO J , vol.22 , pp. 2324-2333
    • Brakebusch, C.1    Fassler, R.2
  • 23
    • 44449137944 scopus 로고    scopus 로고
    • Centrosome separation driven by actin-microfilaments during mitosis is mediated by centrosome-associated tyrosine-phosphorylated cortactin
    • 10.1242/jcs.018176, 18388321
    • Wang W, Chen L, Ding Y, Jin J, Liao K. Centrosome separation driven by actin-microfilaments during mitosis is mediated by centrosome-associated tyrosine-phosphorylated cortactin. J Cell Sci 2008, 121:1334-1343. 10.1242/jcs.018176, 18388321.
    • (2008) J Cell Sci , vol.121 , pp. 1334-1343
    • Wang, W.1    Chen, L.2    Ding, Y.3    Jin, J.4    Liao, K.5
  • 24
    • 0141429921 scopus 로고    scopus 로고
    • A novel mode for integrin-mediated signaling: tethering is required for phosphorylation of FAKY397
    • 10.1091/mbc.E03-01-0046, 207021, 12960434
    • Shi Q, Boettiger D. A novel mode for integrin-mediated signaling: tethering is required for phosphorylation of FAKY397. Mol Biol Cell 2003, 14:4306-4315. 10.1091/mbc.E03-01-0046, 207021, 12960434.
    • (2003) Mol Biol Cell , vol.14 , pp. 4306-4315
    • Shi, Q.1    Boettiger, D.2
  • 26
    • 11244258882 scopus 로고    scopus 로고
    • Focal adhesion kinase: in command and control of cell motility
    • 10.1038/nrm1549, 15688067
    • Mitra SK, Hanson DA, Schlaepfer DD. Focal adhesion kinase: in command and control of cell motility. Nat Rev Mol Cell Biol 2005, 6:56-68. 10.1038/nrm1549, 15688067.
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 56-68
    • Mitra, S.K.1    Hanson, D.A.2    Schlaepfer, D.D.3
  • 27
    • 0037509990 scopus 로고    scopus 로고
    • Focal adhesion kinase: the first ten years
    • Parsons JT. Focal adhesion kinase: the first ten years. J Cell Sci 2003, 15:1409-1416.
    • (2003) J Cell Sci , vol.15 , pp. 1409-1416
    • Parsons, J.T.1
  • 28
    • 0028350859 scopus 로고
    • Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src
    • 358526, 7509446
    • Schaller MD, Hildebrand JD, Shannon JD, Fox JW, Vines RR, Parsons JT. Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src. Mol Cell Biol 1994, 14:1680-1688. 358526, 7509446.
    • (1994) Mol Cell Biol , vol.14 , pp. 1680-1688
    • Schaller, M.D.1    Hildebrand, J.D.2    Shannon, J.D.3    Fox, J.W.4    Vines, R.R.5    Parsons, J.T.6
  • 29
    • 0028877919 scopus 로고
    • Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: a role for Src family kinases
    • 231984, 7529876
    • Calalb MB, Polte TR, Hanks SK. Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: a role for Src family kinases. Mol Cell Biol 1995, 15:954-963. 231984, 7529876.
    • (1995) Mol Cell Biol , vol.15 , pp. 954-963
    • Calalb, M.B.1    Polte, T.R.2    Hanks, S.K.3
  • 33
    • 0030029143 scopus 로고    scopus 로고
    • Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck-and FynT-dependent T cell activation
    • 10.1074/jbc.271.2.695, 8557675
    • Hanks J, Gardner JP, Dow RL, Changelian PS, Brissette WH, Weringer EJ, Pollok BA, Connelly PA. Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck-and FynT-dependent T cell activation. J Biol Chem 1996, 271:695-701. 10.1074/jbc.271.2.695, 8557675.
    • (1996) J Biol Chem , vol.271 , pp. 695-701
    • Hanks, J.1    Gardner, J.P.2    Dow, R.L.3    Changelian, P.S.4    Brissette, W.H.5    Weringer, E.J.6    Pollok, B.A.7    Connelly, P.A.8
  • 34
    • 57349100453 scopus 로고    scopus 로고
    • Distinct phospho-forms of cortactin differentially regulate actin polymerization and focal adhesions
    • Kruchten AD, Krueger EW, Wang Y, McNiven MA. Distinct phospho-forms of cortactin differentially regulate actin polymerization and focal adhesions. Am J Physiol Cell Physiol 2008, 295:1113-1122.
    • (2008) Am J Physiol Cell Physiol , vol.295 , pp. 1113-1122
    • Kruchten, A.D.1    Krueger, E.W.2    Wang, Y.3    McNiven, M.A.4
  • 35
    • 85047696594 scopus 로고    scopus 로고
    • Src kinase contributes to the metastasis spread of carcinoma cells
    • 10.1038/sj.onc.1205298, 11948418
    • Boyer B, Bourgeois Y, Poupon MF. Src kinase contributes to the metastasis spread of carcinoma cells. Oncogene 2002, 21:2347-2356. 10.1038/sj.onc.1205298, 11948418.
    • (2002) Oncogene , vol.21 , pp. 2347-2356
    • Boyer, B.1    Bourgeois, Y.2    Poupon, M.F.3
  • 36
    • 33748086453 scopus 로고    scopus 로고
    • Cortactin overexpression regulates actin-related protein 2/3 complex activity, motility and invasion in carcinomas with chromosome 11q13 amplification
    • 10.1158/0008-5472.CAN-05-4490, 16912177
    • Rothschild BL, Shim AH, Ammer AG, Kelley LC, Irby KB, Head JA, Chen L, Varella-Garcia M, Sacks PG, Frederick B, Raben D, Weed SA. Cortactin overexpression regulates actin-related protein 2/3 complex activity, motility and invasion in carcinomas with chromosome 11q13 amplification. Cancer Res 2006, 66:8017-8025. 10.1158/0008-5472.CAN-05-4490, 16912177.
    • (2006) Cancer Res , vol.66 , pp. 8017-8025
    • Rothschild, B.L.1    Shim, A.H.2    Ammer, A.G.3    Kelley, L.C.4    Irby, K.B.5    Head, J.A.6    Chen, L.7    Varella-Garcia, M.8    Sacks, P.G.9    Frederick, B.10    Raben, D.11    Weed, S.A.12
  • 37
    • 65649119024 scopus 로고    scopus 로고
    • Arg interacts with cortactin to promote adhesion-dependent cell edge protrusion
    • 10.1083/jcb.200809085, 2700396, 19414610
    • Lapetina S, Mader CC, Machida K, Mayer BJ, Koleske AJ. Arg interacts with cortactin to promote adhesion-dependent cell edge protrusion. J Cell Biol 2009, 185:503-519. 10.1083/jcb.200809085, 2700396, 19414610.
    • (2009) J Cell Biol , vol.185 , pp. 503-519
    • Lapetina, S.1    Mader, C.C.2    Machida, K.3    Mayer, B.J.4    Koleske, A.J.5
  • 38
    • 50649090270 scopus 로고    scopus 로고
    • Cortactin Branches Out: Roles in Regulating Protrusive Actin Dynamics
    • 10.1002/cm.20296, 2561250, 18615630
    • Ammer AG, Weed SA. Cortactin Branches Out: Roles in Regulating Protrusive Actin Dynamics. Cell Motil Cytoskeleton 2008, 65:687-707. 10.1002/cm.20296, 2561250, 18615630.
    • (2008) Cell Motil Cytoskeleton , vol.65 , pp. 687-707
    • Ammer, A.G.1    Weed, S.A.2
  • 39
    • 33645507413 scopus 로고    scopus 로고
    • Dynamic interactions of cortactin and membrane type 1 matrix metalloproteinase at invadopodia: defining the stage of invadopodia formation and function
    • 10.1158/0008-5472.CAN-05-2177, 16540652
    • Artym VV, Zhang Y, Seillier-Moiseiwitsch F, Yamada KM, Mueller SC. Dynamic interactions of cortactin and membrane type 1 matrix metalloproteinase at invadopodia: defining the stage of invadopodia formation and function. Cancer Res 2006, 66:3034-3043. 10.1158/0008-5472.CAN-05-2177, 16540652.
    • (2006) Cancer Res , vol.66 , pp. 3034-3043
    • Artym, V.V.1    Zhang, Y.2    Seillier-Moiseiwitsch, F.3    Yamada, K.M.4    Mueller, S.C.5
  • 41
    • 50249107474 scopus 로고    scopus 로고
    • Paxillin comes of age
    • 10.1242/jcs.018044, 2522309, 18650496
    • Deakin NO, Turner CE. Paxillin comes of age. J Cell Sci 2008, 121:2435-2444. 10.1242/jcs.018044, 2522309, 18650496.
    • (2008) J Cell Sci , vol.121 , pp. 2435-2444
    • Deakin, N.O.1    Turner, C.E.2
  • 42
    • 0038514313 scopus 로고    scopus 로고
    • Lipid rafts/caveolae are essential for insulin-like growth factor-1 receptor signaling during 3T3-L1 preadipocyte differentiation induction
    • 10.1074/jbc.M211785200, 12538586
    • Huo H, Guo X, Hong S, Jiang M, Liu X, Liao K. Lipid rafts/caveolae are essential for insulin-like growth factor-1 receptor signaling during 3T3-L1 preadipocyte differentiation induction. J Biol Chem 2003, 278:11561-11569. 10.1074/jbc.M211785200, 12538586.
    • (2003) J Biol Chem , vol.278 , pp. 11561-11569
    • Huo, H.1    Guo, X.2    Hong, S.3    Jiang, M.4    Liu, X.5    Liao, K.6
  • 43
    • 0034602375 scopus 로고    scopus 로고
    • C-Crk, a substrate of the insulin-like growth factor-1 receptor tyrosine kinase, functions as an early signal mediator in the adipocyte differentiation process
    • Jin S, Zhai B, Qiu Z, Wu J, Lane MD, Liao K. c-Crk, a substrate of the insulin-like growth factor-1 receptor tyrosine kinase, functions as an early signal mediator in the adipocyte differentiation process. J Biol Chem 2000, 275:34344-34352.
    • (2000) J Biol Chem , vol.275 , pp. 34344-34352
    • Jin, S.1    Zhai, B.2    Qiu, Z.3    Wu, J.4    Lane, M.D.5    Liao, K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.