Interleukin-1, tumor necrosis factor-alpha, and transforming growth factor-beta 1 and integrative meniscal repair: Influences on meniscal cell proliferation and migration

Arthritis Research and Therapy

Volumn 13, Issue 6, 2011, Pages

  Riera, Katherine M ^a   Rothfusz, Nicole E ^a,b   Wilusz, Rebecca E ^a,b   Weinberg, J B ^a,c   Guilak, Farshid ^a,b   McNulty, Amy L ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b DUKE UNIVERSITY   (United States)

^c DURHAM VA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 1; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL MIGRATION; CELL PROLIFERATION; CELL VIABILITY; CONFOCAL LASER SCANNING MICROSCOPY; CONTROLLED STUDY; EXPLANT; EXTRACELLULAR MATRIX; FEMALE; FLUORESCENCE; KNEE MENISCUS; MENISCAL REPAIR; NONHUMAN; PIG; PROTEIN FUNCTION; SHEAR STRENGTH; TISSUE ENGINEERING; UPREGULATION; WOUND HEALING; ANIMAL; BIOMECHANICS; CELL CULTURE; CELL MOTION; CELL SURVIVAL; CONFOCAL MICROSCOPY; DRUG EFFECT; IN VITRO STUDY; PATHOLOGY; PATHOPHYSIOLOGY; SWINE; TISSUE CULTURE TECHNIQUE;

ANIMALS; BIOMECHANICS; CELL MOVEMENT; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; FEMALE; INTERLEUKIN-1; MENISCI, TIBIAL; MICROSCOPY, CONFOCAL; SWINE; TISSUE CULTURE TECHNIQUES; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR-ALPHA; WOUND HEALING;

EID: 81055148275     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/ar3515     Document Type: Article

References (79)

1. Ahmed AM, Burke DL: In-vitro measurement of static pressure distribution in synovial joints-Part I: Tibial surface of the knee. J Biomech Eng 1983, 105:216-225
2. Markolf KL, Bargar WL, Shoemaker SC, Amstutz HC: The role of joint load in knee stability. J Bone Joint Surg Am 1981, 63:570-585
3. Arnoczky S, McDevitt C: The meniscus: structure, function, repair, and replacement. In Orthopaedic Basic Science. Edited by: Buckwalter J, Einhorn T, Simon S. Rosemont, IL: American Academy of Orthopaedic Surgeons; 2000:531-545
4. Wojtys EM, Chan DB: Meniscus structure and function. AAOS Instructional Course Lectures 2005, 54:323-330
5. Majewski M, Susanne H, Klaus S: Epidemiology of athletic knee injuries: a10-year study. Knee 2006, 13:184-188
6. Christoforakis J, Pradhan R, Sanchez-Ballester J, Hunt N, Strachan RK: Is there an association between articular cartilage changes and degenerative meniscus tears? Arthroscopy 2005, 21:1366-1369
7. Hunter DJ, Zhang YQ, Niu JB, Tu X, Amin S, Clancy M, Guermazi A, Grigorian M, Gale D, Felson DT: The association of meniscal pathologic changes with cartilage loss in symptomatic knee osteoarthritis. Arthritis Rheum 2006, 54:795-801
8. Roos H, Lauren M, Adalberth T, Roos EM, Jonsson K, Lohmander LS: Knee osteoarthritis after meniscectomy: prevalence of radiographic changes after twenty-one years, compared with matched controls. Arthritis Rheum 1998, 41:687-693
9. Wyland DJ, Guilak F, Elliott DM, Setton LA, Vail TP: Chondropathy after meniscal tear or partial meniscectomy in a canine model. J Orthop Res 2002, 20:996-1002
10. Berthiaume MJ, Raynauld JP, Martel-Pelletier J, Labonte F, Beaudoin G, Bloch DA, Choquette D, Haraoui B, Altman RD, Hochberg M, Meyer JM, Cline GA, Pelletier JP: Meniscal tear and extrusion are strongly associated with progression of symptomatic knee osteoarthritis as assessed by quantitative magnetic resonance imaging. Ann Rheum Dis 2005, 64:556-563
11. Sharma L, Eckstein F, Song J, Guermazi A, Prasad P, Kapoor D, Cahue S, Marshall M, Hudelmaier M, Dunlop D: Relationship of meniscal damage, meniscal extrusion, malalignment, and joint laxity to subsequent cartilage loss in osteoarthritic knees. Arthritis Rheum 2008, 58:1716-1726
12. Lohmander LS, Roos H, Dahlberg L, Hoerrner LA, Lark MW: Temporal patterns of stromelysin-1, tissue inhibitor, and proteoglycan fragments in human knee joint fluid after injury to the cruciate ligament or meniscus. J Orthop Res 1994, 12:21-28
13. Arnoczky SP, Warren RF: The microvasculature of the meniscus and its response to injury. An experimental study in the dog. Am J Sports Med 1983, 11:131-141
14. Arnoczky SP, Warren RF: Microvasculature of the human meniscus. Am J Sports Med 1982, 10:90-95
15. Hennerbichler A, Moutos FT, Hennerbichler D, Weinberg JB, Guilak F: Repair response of the inner and outer regions of the porcine meniscus in vitro. Am J Sports Med 2007, 35:754-762
16. Hellio Le Graverand MP, Ou Y, Schield-Yee T, Barclay L, Hart D, Natsume T, Rattner JB: The cells of the rabbit meniscus: their arrangement, interrelationship, morphological variations and cytoarchitecture. J Anat 2001, 198:525-535
17. Upton ML, Chen J, Setton LA: Region-specific constitutive gene expression in the adult porcine meniscus. J Orthop Res 2006, 24:1562-1570
18. Cheung HS: Distribution of type I, II, III and V in the pepsin solubilized collagens in bovine menisci. Connect Tissue Res 1987, 16:343-356
19. Eyre DR, Muir H: The distribution of different molecular species of collagen in fibrous, elastic and hyaline cartilages of the pig. Biochem J 1975, 151:595-602
20. Kambic HE, McDevitt CA: Spatial organization of types I and II collagen in the canine meniscus. J Orthop Res 2005, 23:142-149
21. Kobayashi K, Fujimoto E, Deie M, Sumen Y, Ikuta Y, Ochi M: Regional differences in the healing potential of the meniscus-an organ culture model to eliminate the influence of microvasculature and the synovium. Knee 2004, 11:271-278
22. Kawamura S, Lotito K, Rodeo SA: Biomechanics and healing response of the meniscus. Operative Techniques Sports Med 2003, 11:68-76
23. Hennerbichler A, Moutos FT, Hennerbichler D, Weinberg JB, Guilak F: Interleukin-1 and tumor necrosis factor alpha inhibit repair of the porcine meniscus in vitro. Osteoarthritis Cartilage 2007, 15:1053-1060
24. McNulty AL, Guilak F: Integrative repair of the meniscus: lessons from in vitro studies. Biorheology 2008, 45:487-500
25. McNulty AL, Moutos FT, Weinberg JB, Guilak F: Enhanced integrative repair of the porcine meniscus in vitro by inhibition of interleukin-1 or tumor necrosis factor alpha. Arthritis Rheum 2007, 56:3033-3042
26. McNulty AL, Weinberg JB, Guilak F: Inhibition of matrix metalloproteinases enhances in vitro repair of the meniscus. Clin Orthop Relat Res 2009, 467:1557-1567
27. Wilusz RE, Weinberg JB, Guilak F, McNulty AL: Inhibition of integrative repair of the meniscus following acute exposure to interleukin-1 in vitro. J Orthop Res 2008, 26:504-512
28. Arnoczky SP, Warren RF, Spivak JM: Meniscal repair using an exogenous fibrin clot. An experimental study in dogs. J Bone Joint Surg Am 1988, 70:1209-1217
29. Kambic HE, Futani H, McDevitt CA: Cell, matrix changes and alpha-smooth muscle actin expression in repair of the canine meniscus. Wound Repair Regen 2000, 8:554-561
30. Lotz M: Cytokines in cartilage injury and repair. Clin Orthop Relat Res 2001, 391:S108-115
31. Fernandes JC, Martel-Pelletier J, Pelletier JP: The role of cytokines in osteoarthritis pathophysiology. Biorheology 2002, 39:237-246
32. Kahle P, Saal JG, Schaudt K, Zacher J, Fritz P, Pawelec G: Determination of cytokines in synovial fluids: correlation with diagnosis and histomorphological characteristics of synovial tissue. Ann Rheum Dis 1992, 51:731-734
33. Hopkins SJ, Humphreys M, Jayson MI: Cytokines in synovial fluid. I. The presence of biologically active and immunoreactive IL-1. Clin Exp Immunol 1988, 72:422-427
34. McNulty AL, Estes BT, Wilusz RE, Weinberg JB, Guilak F: Dynamic loading enhances integrative meniscal repair in the presence of interleukin-1. Osteoarthritis Cartilage 2010, 18:830-838
35. Lotz M, Blanco FJ, von Kempis J, Dudler J, Maier R, Villiger PM, Geng Y: Cytokine regulation of chondrocyte functions. J Rheumatol Suppl 1995, 43:104-108
36. van den Berg WB, Joosten LA, van de Loo FA: TNF alpha and IL-1 beta are separate targets in chronic arthritis. Clin Exp Rheumatol 1999, 17(6 Suppl 18):S105-114
37. Shin SJ, Fermor B, Weinberg JB, Pisetsky DS, Guilak F: Regulation of matrix turnover in meniscal explants: role of mechanical stress, interleukin-1, and nitric oxide. J Appl Physiol 2003, 95:308-313
38. Bhargava MM, Attia ET, Murrell GA, Dolan MM, Warren RF, Hannafin JA: The effect of cytokines on the proliferation and migration of bovine meniscal cells. Am J Sports Med 1999, 27:636-643
39. Pangborn CA, Athanasiou KA: Effects of growth factors on meniscal fibrochondrocytes. Tissue Eng 2005, 11:1141-1148
40. Gunja NJ, Uthamanthil RK, Athanasiou KA: Effects of TGF-beta1 and hydrostatic pressure on meniscus cell-seeded scaffolds. Biomaterials 2009, 30:565-573
41. Collier S, Ghosh P: Effects of transforming growth factor beta on proteoglycan synthesis by cell and explant cultures derived from the knee joint meniscus. Osteoarthritis Cartilage 1995, 3:127-138
42. Stewart K, Pabbruwe M, Dickinson S, Sims T, Hollander AP, Chaudhuri JB: The effect of growth factor treatment on meniscal chondrocyte proliferation and differentiation on polyglycolic acid scaffolds. Tissue Eng 2007, 13:271-280
43. Gruber HE, Mauerhan D, Chow Y, Ingram JA, Norton HJ, Hanley EN Jr, Sun Y: Three-dimensional culture of human meniscal cells: extracellular matrix and proteoglycan production. BMC Biotechnol 2008, 8:54
44. Ionescu LC, Lee GC, Garcia GH, Zachry TL, Shah RP, Sennett BJ, Mauck RL: Maturation state-dependent alterations in meniscus integration: implications for scaffold design and tissue engineering. Tissue Eng: Part A 2011, 17:193-203
45. Steinert AF, Palmer GD, Capito R, Hofstaetter JG, Pilapil C, Ghivizzani SC, Spector M, Evans CH: Genetically enhanced engineering of meniscus tissue using ex vivo delivery of transforming growth factor-b1 complementary deoxyribonucleic acid. Tissue Eng 2007, 13:2227-2237
46. Fermor B, Jeffcoat D, Hennerbichler A, Pisetsky DS, Weinberg JB, Guilak F: The effects of cyclic mechanical strain and tumor necrosis factor alpha on the response of cells of the meniscus. Osteoarthritis Cartilage 2004, 12:956-962
47. Basile P, Dadali T, Jacobson J, Hasslund S, Ulrich-Vinther M, Soballe K, Nishio Y, Drissi MH, Langstein HN, Mitten DJ, O'Keefe RJ, Schwarz EM, Awad HA: Freeze-dried tendon allografts as tissue-engineering scaffolds for Gdf5 gene delivery. Mol Ther 2008, 16:466-473
48. Hocking DC, Chang CH: Fibronectin matrix polymerization regulates small airway epithelial cell migration. Am J Physiol Lung Cell Mol Physiol 2003, 285:L169-179
49. Maffulli N, Ewen SW, Waterston SW, Reaper J, Barrass V: Tenocytes from ruptured and tendinopathic achilles tendons produce greater quantities of type III collagen than tenocytes from normal achilles tendons. An in vitro model of human tendon healing. Am J Sports Med 2000, 28:499-505
50. Hembree WC, Ward BD, Furman BD, Zura RD, Nichols LA, Guilak F, Olson SA: Viability and apoptosis of human chondrocytes in osteochondral fragments following joint trauma. J Bone Joint Surg Br 2007, 89:1388-1395
51. Lewis JS, Hembree WC, Furman BD, Tippets L, Cattel D, Huebner JL, Little D, DeFrate LE, Kraus VB, Guilak F, Olson SA: Acute joint pathology and synovial inflammation is associated with increased intra-articular fracture severity in the mouse knee. Osteoarthritis Cartilage 2011, 19:864-873
52. Lewis JL, Deloria LB, Oyen-Tiesma M, Thompson RC Jr, Ericson M, Oegema TR Jr: Cell death after cartilage impact occurs around matrix cracks. J Orthop Res 2003, 21:881-887
53. Ronot X, Sene C, Boschetti E, Hartmann DJ, Adolphe M: Culture of chondrocytes in medium supplemented with fetal calf serum or a serum substitute: Ultroser G. Biol Cell 1984, 51:307-313
54. Frenkel SR, Clancy RM, Ricci JL, Di Cesare PE, Rediske JJ, Abramson SB: Effects of nitric oxide on chondrocyte migration, adhesion, and cytoskeletal assembly. Arthritis Rheum 1996, 39:1905-1912
55. O'Keefe RJ, Puzas JE, Brand JS, Rosier RN: Effect of transforming growth factor-beta on DNA synthesis by growth plate chondrocytes: modulation by factors present in serum. Calcif Tissue Int 1988, 43:352-358
56. Pritchard S, Guilak F: Effects of interleukin-1 on calcium signaling and the increase of filamentous actin in isolated and in situ articular chondrocytes. Arthritis Rheum 2006, 54:2164-2174
57. Qi J, Fox AM, Alexopoulos LG, Chi L, Bynum D, Guilak F, Banes AJ: IL-1beta decreases the elastic modulus of human tenocytes. J Appl Physiol 2006, 101:189-195
58. Molony L, Armstrong L: Cytoskeletal reorganizations in human umbilical vein endothelial cells as a result of cytokine exposure. Exp Cell Res 1991, 196:40-48
59. Kasemkijwattana C, Menetrey J, Goto H, Niyibizi C, Fu FH, Huard J: The use of growth factors, gene therapy and tissue engineering to improve meniscal healing. Mater Sci Eng C-Biomimetic Supramol Syst 2000, 13:19-28
60. Leipzig ND, Eleswarapu SV, Athanasiou KA: The effects of TGF-beta1 and IGF-I on the biomechanics and cytoskeleton of single chondrocytes. Osteoarthritis Cartilage 2006, 14:1227-1236
61. Haudenschild DR, Chen J, Steklov N, Lotz MK, D'Lima DD: Characterization of the chondrocyte actin cytoskeleton in living three-dimensional culture: response to anabolic and catabolic stimuli. Mol Cell Biomech 2009, 6:135-144
62. Gundersen GG, Kim I, Chapin CJ: Induction of stable microtubules in 3T3 fibroblasts by TGF-beta and serum. J Cell Sci 1994, 107:645-659
63. Li J, Chen J, Kirsner R: Pathophysiology of acute wound healing. Clin Dermatol 2007, 25:9-18
64. Li D, Zhang C, Song F, Lubenec I, Tian Y, Song QH: VEGF regulates FGF-2 and TGF-beta1 expression in injury endothelial cells and mediates smooth muscle cells proliferation and migration. Microvasc Res 2009, 77:134-142
65. Izal I, Ripalda P, Acosta CA, Forriol F: In vitro healing of avascular meniscal injuries with fresh and frozen plugs treated with TGF-beta1 and IGF-1 in sheep. Int J Clin Exp Pathol 2008, 1:426-434
66. Mao JJ, Lee CH, Cook JL, Mendelson A, Moioli EK, Yao H: Regeneration of the articular surface of the rabbit synovial joint by cell homing: a proof of concept study. Lancet 2010, 376:440-448
67. DiMicco MA, Sah RL: Integrative cartilage repair: adhesive strength is correlated with collagen deposition. J Orthop Res 2001, 19:1105-1112
68. DiMicco MA, Waters SN, Akeson WH, Sah RL: Integrative articular cartilage repair: dependence on developmental stage and collagen metabolism. Osteoarthritis Cartilage 2002, 10:218-225
69. Ahsan T, Lottman LM, Harwood F, Amiel D, Sah RL: Integrative cartilage repair: inhibition of B-aminopropionitrile. J Orthop Res 1999, 17:850-857
70. Gunja NJ, Dujari D, Chen A, Luengo A, Fong JV, Hung CT: Migration responses of outer and inner meniscus cells to applied direct current electric fields. J Orthop Res 2011, 30:103-111
71. Morales TI: Chondrocyte moves: clever strategies? Osteoarthritis Cartilage 2007, 15:861-871
72. Weinand C, Peretti GM, Adams SB Jr, Bonassar LJ, Randolph MA, Gill TJ: An allogenic cell-based implant for meniscal lesions. Am J Sports Med 2006, 34:1779-1789
73. Weinand C, Peretti GM, Adams SB Jr, Randolph MA, Savvidis E, Gill TJ: Healing potential of transplanted allogeneic chondrocytes of three different sources in lesions of the avascular zone of the meniscus: a pilot study. Arch Orthop Trauma Surg 2006, 126:599-605
74. Peretti GM, Gill TJ, Xu JW, Randolph MA, Morse KR, Zaleske DJ: Cell-based therapy for meniscal repair: a large animal study. Am J Sports Med 2004, 32:146-158
75. Ruiz-Iban MA, Diaz-Heredia J, Garcia-Gomez I, Gonzalez-Lizan F, Elias-Martin E, Abraira V: The effect of the addition of adipose-derived mesenchymal stem cells to a meniscal repair in the avascular zone: an experimental study in rabbits. Arthroscopy 2011
76. Becker R, Pufe T, Kulow S, Giessmann N, Neumann W, Mentlein R, Petersen W: Expression of vascular endothelial growth factor during healing of the meniscus in a rabbit model. J Bone Joint Surg Br 2004, 86:1082-1087
77. Petersen W, Pufe T, Starke C, Fuchs T, Kopf S, Neumann W, Zantop T, Paletta J, Raschke M, Becker R: The effect of locally applied vascular endothelial growth factor on meniscus healing: gross and histological findings. Arch Orthop Trauma Surg 2007, 127:235-240
78. Jackson DW, Whelan J, Simon TM: Cell survival after transplantation of fresh meniscal allografts. DNA probe analysis in a goat model. Am J Sports Med 1993, 21:540-550
79. Wilson CG, Vanderploeg EJ, Zuo F, Sandy JD, Levenston ME: Aggrecanolysis and in vitro matrix degradation in the immature bovine meniscus: mechanisms and functional implications. Arthritis Res Ther 2009, 11:R173