Genetically enhanced engineering of meniscus tissue using ex vivo delivery of transforming growth factor-β1 complementary deoxyribonucleic acid

Tissue Engineering

Volumn 13, Issue 9, 2007, Pages 2227-2237

  Steinert, Andre F ^a,d   Palmer, Glyn D ^a   Capito, Ramille ^a,b   Hofstaetter, Jochen G ^c   Pilapil, Carmencita ^a   Ghivizzani, Steven C ^a   Spector, Myron ^a,b   Evans, Christopher H ^a,e  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c BOSTON CHILDREN S HOSPITAL   (United States)

^d UNIVERSITY OF WÜRZBURG   (Germany)

^e HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL GROWTH; COLLAGEN; DNA; GENE TRANSFER; GENES; TISSUE;

CDNA DELIVERY; GREEN FLUORESCENT PROTEINS; MENISCAL LESIONS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSFORMING GROWTH FACTOR (TGF);

TISSUE ENGINEERING;

ADENOVIRUS VECTOR; BIGLYCAN; COLLAGEN TYPE 1; COLLAGEN TYPE 2; COMPLEMENTARY DNA; DECORIN; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; GLYCOSAMINOGLYCAN; GREEN FLUORESCENT PROTEIN; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ARTICLE; BONE MARROW; CARTILAGE CELL; CATTLE; CELL CULTURE; CONTROLLED STUDY; DNA MODIFICATION; GENE EXPRESSION; HISTOLOGY; IMMUNOHISTOCHEMISTRY; KNEE MENISCUS; MESENCHYMAL STEM CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TISSUE ENGINEERING; TRANSGENE; VIRAL GENE DELIVERY SYSTEM;

ANIMALS; CATTLE; CELLS, CULTURED; DNA, COMPLEMENTARY; GENE TRANSFER TECHNIQUES; GENES, REPORTER; GENETIC ENGINEERING; HUMANS; MENISCI, TIBIAL; MESENCHYMAL STEM CELLS; RECOMBINANT PROTEINS; TISSUE ENGINEERING; TRANSFORMING GROWTH FACTOR BETA1;

ADENOVIRIDAE; BOVINAE;

EID: 34548644074     PISSN: 10763279     EISSN: None     Source Type: Journal    
DOI: 10.1089/ten.2006.0270     Document Type: Article

References (47)

1. Buma, P., Ramrattan, N.N., van Tienen, T.G., and Veth, R.P. Tissue engineering of the meniscus. Biomaterials 25, 1523, 2004.
2. Sweigart, M.A., and Athanasiou, K.A. Toward tissue engineering of the knee meniscus. Tissue Eng. 7, 111, 2001.
3. Burks, R.T., Metcalf, M.H., and Metcalf, R.W. Fifteen-year follow-up of arthroscopic partial meniscectomy. Arthroscopy 13, 673, 1997.
4. Allen, P.R., Denham, R.A., and Swan, A.V. Late degenerative changes after meniscectomy. Factors affecting the knee after operation. J Bone Joint Surg Br. 66, 666, 1984.
5. Arnoczky, S.P. Building a meniscus. Biologic considerations. Clin Orthop. 367, S244, 1999.
6. Rodkey, W.G. Basic biology of the meniscus and response to injury. Instr Course Lect. 49, 189, 2000.
7. Peretti. G.M., Gill, T.J., Xu, J.W., Randolph, M.A., Morse, K.R., and Zaleske, D.J. Cell-based therapy for meniscal repair: a large animal study. Am J Sports Med. 32, 146, 2004.
8. Murphy, J.M., Fink, D.J., Hunziker, E.B., and Barry, F.P. Stem cell therapy in a caprine model of osteoarthritis. Arthritis Rheum. 48, 3464, 2003.
9. Caplan, AI. Mesenchymal stem cells: cell-based reconstructive therapy in orthopedics. Tissue Eng. 11, 1189, 2005.
10. Pittenger, M.F., Mackay, A.M., and Beck, S.C., Multilineage potential of adult human mesenchymal stem cells. Science 284, 143, 1999.
11. Noth, U., Osyczka, A.M., Tuli, R., Hickok, N.J., Danielson, K.G., and Tuan, R.S. Multilineage mesenchymal differentiation potential of human trabecular bone-derived cells. J Orthop Res. 20, 1060, 2002.
12. Zuk, P.A., Zhu, M., Mizuno, H., Huang, J., Futrell, J.W., Katz, A.J., Benhaim, P., Lorenz, H.P., and Hedrick, M.H. Multilineage cells from human adipose tissue: implications for cell-based therapies. Tissue Eng. 7, 211, 2001.
13. Peng, H., and Huard, J. Muscle-derived stem cells for musculoskeletal tissue regeneration and repair. Transpl Immunol. 12, 311, 2004.
14. Yoo, J.U., Barthel, T.S., Nishimura, K., Solchaga, L., Caplan, A.I., Goldberg, V.M., and Johnstone, B. The chondrogenic potential of human bone-marrow-derived mesenchymal progenitor cells. J Bone Joint Surg Am. 80, 1745, 1998.
15. Walsh, C.J., Goodman, D., Caplan, A.I., and Goldberg, V.M. Meniscus regeneration in a rabbit partial meniscectomy model. Tissue Eng. 5, 327, 1999.
16. Johnstone, B., Hering, T.M., Caplan, A.I., Goldberg, V.M., and Yoo, J.U. In vitro chondrogenesis of bone marrow-derived mesenchymal progenitor cells. Exp Cell Res. 238, 265, 1998.
17. Barry, F., Boynton, R.E., Liu, B., and Murphy, J.M. Chondrogenic differentiation of mesenchymal stem cells from bone marrow: differentiation- dependent gene expression of matrix components. Exp Cell Res. 268, 189, 2001.
18. Pangborn, C., and Athanasiou, K.A. Effects of growth factors on meniscal fibrochondrocytes. Tissue Eng. 11, 1149, 2005.
19. Evans, C.H., and Robbins, P.D. Genetically augmented tissue engineering of the musculoskeletal system. Clin Orthop. 367, S410, 1999.
20. Evans C.H., Ghivizzani S.C., Herndon J.H., and Robbins P.D. Gene therapy for the treatment of musculoskeletal diseases. J Am Acad Orthop Surg. 13, 230, 2005.
21. Goto, H., Shuler, F.D., Niyibizi, C., Fu, F.H., Robbins, P.D., and Evans, C.H. Gene therapy for meniscal injury: enhanced synthesis of proteoglycan and collagen by meniscal cells transduced with a TGF-β1 gene. Osteoarthritis Cartilage 8, 266, 2000.
22. Goto, H., Shuler, F.D., Lamsam, C., Moller, H.D., Niyibizi, C., Fu, F.H., Robbins P.D., and Evans, C.H. Transfer of lacZ marker gene to the meniscus. J Bone Joint Surg Am. 81, 918, 1999.
23. Mueller, S.M., Shortkroff, S., Schneider, T.O., Breinan, H.A., Yannas, I.V., and Spector, M. Meniscus cells seeded in type I and type II collagen-GAG matrices in vitro. Biomaterials 20, 701, 1999.
24. Hardy, S., Kitamura, M., Harris-Stansil, T., Dai, Y., and Phipps, M.L. Construction of adenovirus vectors through Crelox recombination. J Virol. 71, 1842, 1997.
25. Palmer, G., Gouze, E., Gouze, J.N., Betz, O., Evans, C.H., and Ghivizzani, S.C. Gene transfer to articular chondrocytes with recombinant adenovirus. Methods Mol Biol. 215, 235, 2003.
26. Haynesworth, S.E., Goshima, J., Goldberg, V.M., and Caplan, A.I. Characterization of cells with osteogenic potential from human marrow. Bone 13, 81, 1992.
27. Yannas, I.V., Lee, E., Orgill, D.P., Skrabut, E.M., and Murphy, G.F. Synthesis and characterization of a model extracellular matrix which induces partial regeneration of adult mammalian skin. Proc Natl Acad Sci USA 1989; 86: 933-7.
28. Veilleux, N.H., Yannas, I.V., and Spector, M. Effect of passage number and collagen type on the proliferative, biosynthetic, and contractile activity of adult canine articular chondrocytes in type I and II collagen- glycosaminoglycan matrices in vitro. Tissue Eng. 10, 119, 2004.
29. Mueller, S.M., Schneider, T.O., Shortkroff, S., Breinan, H.A., and Spector, M. Alpha-smooth muscle actin and contractile behavior of bovine meniscus cells seeded in type 1 and type II collagen-GAG matrices. J Biomed Mater Res 45, 157, 1999.
30. Lee, C.R., Grodzinsky, A.J., and Spector, M. The effects of cross-linking of collagen-glycosaminoglycan scaffolds on compressive stiffness, chondrocyte-mediated contraction, proliferation and biosynthesis. Biomaterials 22, 3145, 2001.
31. Farndale, R.W., Sayers, C.A., and Barrett, A.J. A direct spectrophotometric microassay for sulfated glycosaminoglycans in cartilage cultures. Connect Tissue Res. 9, 247, 1982.
32. Chomczynski, P., and Sacchi, N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem. 162, 156, 1987.
33. Hunter, C.J., Imler, S.M., Malaviya, P., Nerem, R.M., and Levenston, M.E. Mechanical compression alters gene expression and extracellular matrix synthesis by chondrocytes cultured in collagen I gels. Biomaterials 23, 1249, 2002.
34. Rees, S.G., Flannery, C.R., Little, C.B., Hughes, C.E., Caterson, B., and Dent C.M. Catabolism of aggrecan, decorin and biglycan in tendon. Biochem J. 350, 181, 2000.
35. van Susante, J.L.C., Pieper, J., Buma, P., van Kuppevelt, T.H., van Beuningen, H., van Der Kraan, P.M., Veerkamp, J.H., van den Berg, W.B., and Veth, R.P.H. Linkage of chondroitin-sulfate to type 1 collagen scaffolds stimulates the bioactivity of seeded chondrocytes in vitro. Biomaterials 22, 2359, 2001.
36. Martinek, V., Usas, A., Pelinkovic, D., Robbins, P., Fu, F.H., and Huard, J. Genetic engineering of meniscal allografts. Tissue Eng. 8, 107, 2002.
37. Palmer, G.D., Steinert, A., Pascher, A., Gouze, E., Gouze, J.N., Betz, O,, Johnstone, B., Evans, C.H., and Ghivizzani, S.C. Gene-induced chondrogenesis of primary mesenchymal stem cells in vitro. Mol Ther. 12, 219, 2005.
38. Collier, S., and Ghosh, P. Effects of transforming growth factor beta on proteoglycan synthesis by cell and explant cultures derived from the knee joint meniscus. Osteoarthritis Cartilage 3, 127, 1995.
39. Zaleskas, J.M., Kinner, B., Freyman, T.M., Yannas, I.V., Gibson, L.J., and Spector, M. Growth factor regulation of smooth muscle actin expression and contraction of human articular chondrocytes and meniscal cells in a collagen-GAG matrix. Exp Cell Res. 270, 21, 2001.
40. Pangborn, C.A., and Athanasiou, K.A. Growth factors and fibrochondrocytes in scaffolds. J Orthop Res. 23, 1184, 2005.
41. Adams, S.B. Jr., Randolph. M.A., and Gill, T.J. Tissue engineering for meniscus repair. J Knee Surg. 18, 25, 2005.
42. Ramrattan, N.N., Heijkants, R.G., van Tienen, T.G., Schouten, A.J., Veth, R.P., and Buma, P. Assessment of tissue ingrowth rates in polyurethane scaffolds for tissue engineering. Tissue Eng. 11, 1212, 2005.
43. Aufderheide, A.C., and Athanasiou, K.A. Comparison of scaffolds and culture conditions for tissue engineering of the knee meniscus. Tissue Eng. 11, 1095, 2005.
44. Vickers, S.M., Squitieri, L.S., and Spector, M. Effects of cross-linking type II collagen-GAG scaffolds on chondrogenesis in vitro: dynamic pore reduction promotes cartilage formation. Tissue Eng. 12, 1345, 2006.
45. Hidaka, C., Ibarra, C., Hannafin, J.A., Torzilli, P., Quitoriano, M., Jen, S., Warren, R., and Crystal, R. Formation of vascularized meniscal tissue by combining gene therapy with tissue engineering. Tissue Eng. 8, 93, 2001.
46. Yamasaki, T., Deie, M., Shinomiya, R., Izuta, Y., Yasunaga, Y., Yanada, S., Sharman, P., and Ochi, M. Meniscal regeneration using tissue engineering with a scaffold derived from a rat meniscus and mesenchymal stromal cells derived from rat bone marrow. J Biomed Mater Res. 75, 23, 2005.
47. Mi, Z., Ghivizzani, S.C., Lechman, E., Glorioso, J.C., Evans, C.H., and Robbins, P.D. Adverse effects of adenovirus-mediated gene transfer of human transforming growth factor beta 1 into rabbit knees. Arthritis Res Ther 5, 132, 2003.