Region-specific constitutive gene expression in the adult porcine meniscus

Journal of Orthopaedic Research

Volumn 24, Issue 7, 2006, Pages 1562-1570

  Upton, Maureen L ^a   Chen, Jun ^a   Setton, Lori A ^a,b  

^a Duke University   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Collagen; Gene expression; Meniscus; Meniscus cell culture; Region

Indexed keywords

AGGRECAN; BIOLOGICAL MARKER; COLLAGEN TYPE 1; COLLAGEN TYPE 2; GELATINASE A; INDUCIBLE NITRIC OXIDE SYNTHASE; MESSENGER RNA; SCLEROPROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE CELL; CELL CULTURE; CELL ISOLATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; GENE EXPRESSION PROFILING; KNEE MENISCUS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RNA ANALYSIS; TISSUE CULTURE; TISSUE DISTRIBUTION;

ANIMALS; CELLS, CULTURED; COLLAGEN; GENE EXPRESSION; GENE EXPRESSION PROFILING; HIGH MOBILITY GROUP PROTEINS; MENISCI, TIBIAL; NITRIC OXIDE SYNTHASE TYPE II; PEPTIDE HYDROLASES; PROTEOGLYCANS; SWINE; TRANSCRIPTION FACTORS;

EID: 33646883585     PISSN: 07360266     EISSN: None     Source Type: Journal    
DOI: 10.1002/jor.20146     Document Type: Article

References (53)

1. Ahmed AM. 1992. The load-bearing role of the knee menisci. In: Mow VC, Arnoczky SP, Jackson DW, editors. Knee meniscus: basic and clinical foundations. New York: Raven Press.
2. Levy IM, Torzilli PA, Fisch ID. 1992. The contribution of the menisci to the stability of the knee. In: Mow VC, Arnoczky SP, Jackson DW, editors. Knee meniscus. Basic and clinical foundations. New York: Raven Press.
3. Arnoczky SP, Warren RF. 1983. The microvasculature of the meniscus and its response to injury: an experimental study in the dog. Am J Sports Med 11:131-141.
4. Adams MA, Hukins DWL. 1992. The extracellular matrix of the meniscus. In: Mow VC, Arnoczky SP, Jackson DW, editors. Knee meniscus: basic and clinical foundations. New York: Raven Press.
5. McDevitt CA, Webber RJ. 1990. The ultrastructure and biochemistry of meniscal cartilage. Clin Orthop 252:8-18.
6. LeRoux MA, Upton ML, Laursen TA, et al. 2001. Biphasic finite element modeling of tear effects on the mechanics of the meniscus. Trans ASME Bioeng Div 50: 851-852.
7. Spilker RL, Donzelli PS, Mow VC. 1992. A transversely isotropic biphasic finite element model of the meniscus. J Biomech 25:1027-1045.
8. Zhang H. 2000. PhD thesis: geometric and finite element modeling of the tibio-menisco-femoral contact under passive knee joint motion. Rochester, NY: University of Rochester, Mechanical Engineering.
9. McCarty EC, Marx RG, DeHaven KE. 2002. Meniscus repair: considerations in treatment and update of clinical results. Clin Orthop 402:122-134.
10. Cheung HS. 1987. Distribution of type I, II, III and V in the pepsin solubilized collagens in bovine menisci. Connect Tissue Res 16:343-356.
11. Kambic HE, McDevitt CA. 2005. Spatial organization of types I and II collagen in the canine meniscus. J Orthop Res 23:142-149.
12. Roughley PJ, White RJ. 1992. The dermatan sulfate proteoglycans of the adult human meniscus. J Orthop Res 10:631-637.
13. Collier S, Ghosh P. 1995. Effects of transforming growth factor beta on proteoglycan synthesis by cell and explant cultures derived from the knee joint meniscus. Osteoarthritis Cartilage 3:127-138.
14. Valiyavettil M, Mort JS, McDevitt CA. 2005. The concentration, gene expression, and spatial distribution of aggrecan in canine articular cartilage, meniscus, and anterior and posterior curciate ligaments: a new molecular distinction between hyaline cartilage and fibrocartilage in the knee joint. Connect Tissue Res 46: 83-91.
15. Ghadially FN, Tomas I, Lalonde NY, et al. 1978. Ultrastructure of rabbit semilunar cartilages. J Anat 125:499-517.
16. McDevitt CA, Miller RR, Spindler KP. 1992. The cells and cell matrix interactions of the meniscus. In: Mow VC, Arnoczky SP, Jackson DW, editors. Knee meniscus: basic and clinical foundations. New York: Raven Press.
17. McDevitt CA, Mukherjee S, Kambic H, et al. 2002. Emerging concepts of the cell biology of the meniscus. Curr Opin Orthop 13:345-350.
18. Hellio Le Graverand MP, Ou Y, Schield-Yee T, et al. 2001. The cells of the rabbit meniscus: their arrangement, interrelationship, morphological variations and cytoarchitecture. J Anat 198:525-535.
19. Nakata K, Shino K, Hamada M, et al. 2001. Human meniscus cell: characterization of the primary culture and use for tissue engineering. Clin Orthop 391S:S208-S218.
20. Verdonk PCM, Forsyth RG, Wang J, et al. 2005. Characterisation of human knee meniscus cell phenotype. Osteoarthritis Cartilage 13:548-560.
21. Melrose J, Smith S, Cake M, et al. 2005. Comparative spatial and temporal localisation of perlecan, aggrecan and type I, II and IV collagen in the ovine meniscus: an ageing study. Histoch Cell Biol 19:1-11.
22. Spindler KP, Miller RR, Andrish JT, et al. 1994. Comparison of collagen synthesis in the peripheral and central region of the canine meniscus. Clin Orthop 303:256-263.
23. Bhargava M, Attia E, Murrell G, et al. 1999. The effect of cytokines on the proliferation and migration of bovine meniscal cells. Am J Sports Med 27:636-642.
24. Spindler KP, Mayes C, Miller R, et al. 1995. Regional mitogenic response of the meniscus to platelet-derived growth factor (PDGF-AB). J Orthop Res 13:201-207.
25. Hellio Le Graverand MP, Reno C, Hart DA. 1999. Gene expression in menisci from the knees of skeletally immature and mature female rabbits. J Orthop Res 17: 738-744.
26. Wildey GM, McDevitt CA. 1998. Matrix protein mRNA levels in canine meniscus cells in vitro. Arch Biochem Biophys 353:10-15.
27. Peretti GM, Grill TJ, Xu J-W, et al. 2004. Cell-based therapy for meniscal repair: a large animal study. Am J Sports Med 32:146-158.
28. Fermor B, Jeffcoat D, Hennerbichler A, et al. 2004. The effects of cyclic mechanical strain and tumor necrosis factor alpha on the response of cells of the meniscus. Osteoarthritis Cartilage 12:956-962.
29. Fink C, Fermor B, Weinberg JB, et al. 2001. The effect of dynamic mechanical compression on nitric oxide production in the meniscus. Osteoarthritis Cartilage 9:481-487.
30. Scott PG, Nakano T, Dodd CM. 1997. Isolation and characterization of small proteoglycans from different zones of the porcine knee meniscus. Biochim Biophys Acta 1336:254-262.
31. Shin SJ, Fermor B, Weinberg JB, et al. 2003. Regulation of matrix turnover in meniscal explants: role of mechanical stress, interleukin-1, and nitric oxide. J Appl Physiol 95: 308-313.
32. Upton ML, Chen J, Guilak F, et al. 2003. Differential effects of static and dynamic compression on meniscal cell gene expression. J Orthop Res 21:963-969.
33. Sweigart MA, Zhu CF, Burt DM, et al. 2004. Intraspecies and interspecies comparison of the compressive properties of the medial meniscus. Ann Biomed Eng 32:1569-1579.
34. Reno C, Marchuk L, Sciore P, et al. 1997. Rapid isolation of total RNA from small samples of hypocellular, dense connective tissues. BioTechniques 22:1082-1086.
35. Chen J, Baer AE, Paik PY, et al. 2002. Matrix protein gene expression in intervertebral disc cells subjected to altered osmolarity. Biochem Biophys Res Commun 293:932-938.
36. -ΔΔCt method. Methods 25:402-408.
37. Lefebvre V, Crombrugghe Bd. 1998. Toward understanding SOX9 function in chondrocyte differentiation. Matrix Biol 16:529-540.
38. Pelletier JP, DiBattista JA, Roughley P, et al. 1993. Cytokines and inflammation in cartilage degradation. Rheum Dis Clin North Am 19:545-568.
39. Bland YS, Ashburst DE. 1996. Changes in the content of the fibrillar collagens and the expression of their mRNAs in the menisci of rabbit knee joint during development and ageing. Histochem J 28:265-274.
40. Ikeda T, Kamekura S, Mabuchi A, et al. 2004. The combination of SOX5, SOX6, and SOX9 (the SOX Trio) provides signal sufficient for induction of permanent cartilage. Arthritis Rheum 50:3561-3573.
41. Lefebvre V, Li P, De Crombrugghe B. 1998. A new long form of SOX5 (L-SOX5), SOX6 and SOX9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene. EMBO J 17:5718-5733.
42. Aigner T, Gebhard PM, Schmid E, et al. 2003. SOX9 expression does not correlate with type II collagen expression in adult articular chondrocytes. Matrix Biol 22:363-372.
43. Kypriotou M, Fossard-demoor M, Chadjichristos C, et al. 2003. SOX9 exerts a bifunctional effect on type II collagen gene (COL2A1) expression in chondrocytes depending on the differentiation state. DNA Cell Biol 22:2.
44. Somerville RP, Oblander SA, Apte SS. 2003. Matrix metalloproteinases: old dogs with new tricks. Genome Biol 4:216-227.
45. Bluteau G, Conrozier T, Mathieu P, et al. 2001. Matrix metalloproteinase-1, -3, -13 and aggrecanase-1 and -2 are differentially expressed in experimental osteoarthritis. Biochim Biophys Acta 1526:147-158.
46. Hellio Le Graverand MP, Vignon E, Otterness IG, et al. 2001. Early changes in lapine menisci during osteoarthritis development Part II: molecular alterations. Osteoarthritis Cartilage 9:65-72.
47. Vincenti MP, Brinckerhoff CE. 2002. Transcriptional regulation of collagenase (MMP-1, MMP-13) genes in arthritis: integration of complex signaling pathways for the recruitment of gene-specific transcription factors. Arthritis Res 4:157-164.
48. Vincenti MP, White LA, Schroen DJ, et al. 1996. Regulating expression of the gene for matrix metalloproteinase-1 (collagenase): mechanisms that control enzyme activity, transcription, and mRNA stability. Crit Rev Eukaryot Gene Expr 6:391-411.
49. Kobayashi K, Mishima H, Hashimoto S, et al. 2001. Chondrocyte apoptosis and regional differential expression of nitric oxide in the medial meniscus following partial meniscectomy. J Orthop Res 19:802-808.
50. Cao M, Stefanovic-Racic M, Georgescu HI, et al. 1998. Generation of nitric oxide by lapine mensical cells and its effect on matrix metabolism: stimulation of collagen production by arginine. J Orthop Res 16:104-111.
51. Hashimoto S, Takahashi K, Ochs RL, et al. 1999. Nitric oxide production and apoptosis in cells of the meniscus during experimental osteoarthritis. Arthritis Rheum 42:2123-2131.
52. Benya PD, Shaffer JD. 1982. Dedifferentiated chondrocytes reexpress the differentiated collagen phenotype when cultured in agarose gels. Cell 30:215-224.
53. Wang JY, Baer AE, Kraus VB, et al. 2001. Intervertebral disc cells exhibit differences in gene expression in alginate and monolayer culture. Spine 26:1747-1751.