-
1
-
-
0031871101
-
Studies with purified chaperones advance the understanding of the mechanism of glucocorticoid receptor-hsp90 heterocomplex assembly
-
DOI 10.1016/S1043-2760(98)00059-9, PII S1043276098000599
-
Pratt WB, Dittmar KD (1998) Studies with purified chaperones advance the understanding of the mechanism of glucocorticoid receptor-hsp90 heterocomplex assembly. Trends Endocrin Met 9:244-252. (Pubitemid 28357616)
-
(1998)
Trends in Endocrinology and Metabolism
, vol.9
, Issue.6
, pp. 244-252
-
-
Pratt, W.B.1
Dittmar, K.D.2
-
2
-
-
0034892432
-
Hsp90: Chaperoning signal transduction
-
DOI 10.1002/jcp.1131
-
Richter K, Buchner J (2001) Hsp90: chaperoning signal transduction. J Cell Physiol 188:281-290. (Pubitemid 32777169)
-
(2001)
Journal of Cellular Physiology
, vol.188
, Issue.3
, pp. 281-290
-
-
Richter, K.1
Buchner, J.2
-
3
-
-
0036810352
-
Heat-shock protein 90, a chaperone for folding and regulation
-
Picard D (2002) Heat-shock protein 90, a chaperone for folding and regulation. Cell Mol Life Sci 59:1640-1648.
-
(2002)
Cell Mol Life Sci
, vol.59
, pp. 1640-1648
-
-
Picard, D.1
-
4
-
-
0037036458
-
cdc37
-
DOI 10.1074/jbc.M201287200
-
Siligardi G, et al. (2002) Regulation of Hsp90 ATPase activity by the co-chaperone Cdc37p/p50(cdc97). J Biol Chem 277:20151-20159. (Pubitemid 34967306)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.23
, pp. 20151-20159
-
-
Siligardi, G.1
Panaretou, B.2
Meyerc, P.3
Singh, S.4
Woolfson, D.N.5
Piper, P.W.6
Pearl, L.H.7
Prodromou, C.8
-
5
-
-
10644265069
-
Co-chaperone regulation of conformational switching in the Hsp90 ATPase cycle
-
DOI 10.1074/jbc.M410562200
-
Siligardi G, et al. (2004) Co-chaperone regulation of conformational switching in the Hsp90 ATPase cycle. J Biol Chem 279:51989-51998. (Pubitemid 39656569)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.50
, pp. 51989-51998
-
-
Siligardi, G.1
Hu, B.2
Panaretou, B.3
Piper, P.W.4
Pearl, L.H.5
Prodromou, C.6
-
6
-
-
0033081968
-
Regulation of Hsp90 ATPase activity by tetratricopeptide repeat (TPR)-domain co-chaperones
-
DOI 10.1093/emboj/18.3.754
-
Prodromou C, et al. (1999) Regulation of Hsp90 ATPase activity by tetratricopeptide repeat (TPR)-domain co-chaperones. EMBO J 18:754-762. (Pubitemid 29057260)
-
(1999)
EMBO Journal
, vol.18
, Issue.3
, pp. 754-762
-
-
Prodromou, C.1
Siligardi, G.2
O'Brien, R.3
Woolfson, D.N.4
Regan, L.5
Panaretou, B.6
Ladbury, J.E.7
Piper, P.W.8
Pearl, L.H.9
-
7
-
-
0037064023
-
The assembly and intermolecular properties of the hsp70-Hop-hsp90 molecular chaperone complex
-
DOI 10.1074/jbc.M206566200
-
Hernandez MP, Sullivan WP, Toft DO (2002) The assembly and intermolecular properties of the hsp70-Hop-hsp90 molecular chaperone complex. J Biol Chem 277: 38294-38304. (Pubitemid 35154683)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.41
, pp. 38294-38304
-
-
Patricia, H.M.1
Sullivan, W.P.2
Toft, D.O.3
-
8
-
-
33746364784
-
Structure and mechanism of the Hsp90 molecular chaperone machinery
-
DOI 10.1146/annurev.biochem.75.103004.142738
-
Pearl LH, Prodromou C (2006) Structure and mechanism of the Hsp90 molecular chaperone machinery. Annu Rev Biochem 75:271-294. (Pubitemid 44118034)
-
(2006)
Annual Review of Biochemistry
, vol.75
, pp. 271-294
-
-
Pearl, L.H.1
Prodromou, C.2
-
9
-
-
0032538995
-
In vivo function of Hsp90 is dependent on ATP binding and ATP hydrolysis
-
DOI 10.1083/jcb.143.4.901
-
Obermann WMJ, Sondermann H, Russo AA, Pavletich NP, Hartl FU (1998) In vivo function of Hsp90 is dependent on ATP binding and ATP hydrolysis. J Cell Biol 143:901-910. (Pubitemid 28547391)
-
(1998)
Journal of Cell Biology
, vol.143
, Issue.4
, pp. 901-910
-
-
Obermann, W.M.J.1
Sondermann, H.2
Russo, A.A.3
Pavletich, N.P.4
Hartl, F.U.5
-
10
-
-
0033581021
-
The importance of ATP binding and hydrolysis by hsp90 in formation and function of protein heterocomplexes
-
Grenert JP, Johnson BD, Toft DO (1999) The importance of ATP binding and hydrolysis by hsp90 in formation and function of protein heterocomplexes. J Biol Chem 274: 17525-17533.
-
(1999)
J Biol Chem
, vol.274
, pp. 17525-17533
-
-
Grenert, J.P.1
Johnson, B.D.2
Toft, D.O.3
-
12
-
-
56849131626
-
Species-dependent ensembles of conserved conformational states define the Hsp90 chaperone ATPase cycle
-
Southworth DR, Agard DA (2008) Species-dependent ensembles of conserved conformational states define the Hsp90 chaperone ATPase cycle. Mol Cell 32:631-640.
-
(2008)
Mol Cell
, vol.32
, pp. 631-640
-
-
Southworth, D.R.1
Agard, D.A.2
-
13
-
-
0029889955
-
A model of protein targeting mediated by immunophilins and other proteins that bind to hsp90 via tetratricopeptide repeat domains
-
DOI 10.1074/jbc.271.23.13468
-
Owens-Grillo JK, et al. (1996) A model of protein targeting mediated by immunophilins and other proteins that bind to hsp90 via tetratricopeptide repeat domains. J Biol Chem 271:13468-13475. (Pubitemid 26185390)
-
(1996)
Journal of Biological Chemistry
, vol.271
, Issue.23
, pp. 13468-13475
-
-
Owens-Grillo, J.K.1
Czar, M.J.2
Hutchison, K.A.3
Hoffmann, K.4
Perdew, G.H.5
Pratt, W.B.6
-
14
-
-
0030925683
-
Steroid receptor interactions with heat shock protein and immunophilin chaperones
-
DOI 10.1210/er.18.3.306
-
Pratt WB, Toft DO (1997) Steroid receptor interactions with heat shock protein and immunophilin chaperones. Endocr Rev 18:306-360. (Pubitemid 27246880)
-
(1997)
Endocrine Reviews
, vol.18
, Issue.3
, pp. 306-360
-
-
Pratt, W.B.1
Toft, D.O.2
-
15
-
-
0032567434
-
Hop as an adaptor in the heat shock protein 70 (Hsp70) and Hsp90 chaperone machinery
-
Chen SY, Smith DF (1998) Hop as an adaptor in the heat shock protein 70 (Hsp70) and Hsp90 chaperone machinery. J Biol Chem 273:35194-35200.
-
(1998)
J Biol Chem
, vol.273
, pp. 35194-35200
-
-
Chen, S.Y.1
Smith, D.F.2
-
16
-
-
0344628648
-
TPR proteins: The versatile helix
-
DOI 10.1016/j.tibs.2003.10.007
-
D'Andrea LD, Regan L (2003) TPR proteins: the versatile helix. Trends Biochem Sci 28:655-662. (Pubitemid 37500900)
-
(2003)
Trends in Biochemical Sciences
, vol.28
, Issue.12
, pp. 655-662
-
-
D'Andrea, L.D.1
Regan, L.2
-
17
-
-
0034646511
-
Structure of TPR domain-peptide complexes: Critical elements in the assembly of the Hsp70-Hsp90 multichaperone machine
-
DOI 10.1016/S0092-8674(00)80830-2
-
Scheufler C, et al. (2000) Structure of TPR domain-peptide complexes: critical elements in the assembly of the Hsp70-Hsp90 multichaperone machine. Cell 101:199-210. (Pubitemid 32004747)
-
(2000)
Cell
, vol.101
, Issue.2
, pp. 199-210
-
-
Scheufler, C.1
Brinker, A.2
Bourenkov, G.3
Pegoraro, S.4
Moroder, L.5
Bartunik, H.6
Hartl, F.U.7
Moarefi, I.8
-
18
-
-
0034629150
-
The Hsp organizer protein Hop enhances the rate of but is not essential for glucocorticoid receptor folding by the multiprotein Hsp90-based chaperone system
-
DOI 10.1074/jbc.275.10.6894
-
Morishima Y, et al. (2000) The Hsp organizer protein Hop enhances the rate of but is not essential for glucocorticoid receptor folding by the multiprotein Hsp90-based chaperone system. J Biol Chem 275:6894-6900. (Pubitemid 30146230)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.10
, pp. 6894-6900
-
-
Morishima, Y.1
Kanelakis, K.C.2
Silverstein, A.M.3
Dittmar, K.D.4
Estrada, L.5
Pratt, W.B.6
-
19
-
-
0037518202
-
Sti1 is a non-competitive inhibitor of the Hsp90 ATPase. Binding prevents the N-terminal dimerization reaction during the ATPase cycle
-
DOI 10.1074/jbc.M213094200
-
Richter K, Muschler P, Hainzl O, Reinstein J, Buchner J (2003) Sti1 is a non-competitive inhibitor of the Hsp90 ATPase - binding prevents the N-terminal dimerization reaction during the ATPase cycle. J Biol Chem 278:10328-10333. (Pubitemid 36800295)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.12
, pp. 10328-10333
-
-
Richter, K.1
Muschler, P.2
Hainzl, O.3
Reinstein, J.4
Buchner, J.5
-
21
-
-
79959299594
-
Hsp90 can accommodate the simultaneous binding of the FKBP52 and Hop proteins
-
Hildenbrand ZL, et al. (2011) Hsp90 can accommodate the simultaneous binding of the FKBP52 and Hop proteins. Oncotarget 2:45-58.
-
(2011)
Oncotarget
, vol.2
, pp. 45-58
-
-
Hildenbrand, Z.L.1
-
22
-
-
78650983812
-
Mixed Hsp90 - Cochaperone complexes are important for the progression of the reaction cycle
-
Li J, Richter K, Buchner J (2011) Mixed Hsp90 - cochaperone complexes are important for the progression of the reaction cycle. Nat Struct Mol Biol 18:61-66.
-
(2011)
Nat Struct Mol Biol
, vol.18
, pp. 61-66
-
-
Li, J.1
Richter, K.2
Buchner, J.3
-
23
-
-
0032541163
-
Specific binding of tetratricopeptide repeat proteins to the C-terminal 12-kDa domain of hsp90
-
DOI 10.1074/jbc.273.29.18007
-
Young JC, Obermann WMJ, Hartl FU (1998) Specific binding of tetratricopeptide repeat proteins to the C-terminal 12-kDa domain of hsp90. J Biol Chem 273: 18007-18010. (Pubitemid 28334712)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.29
, pp. 18007-18010
-
-
Young, J.C.1
Obermann, W.M.J.2
Hartl, F.U.3
-
25
-
-
34548426979
-
The role of mass spectrometry in structure elucidation of dynamic protein complexes
-
Sharon M, Robinson CV (2007) The role of mass spectrometry in structure elucidation of dynamic protein complexes. Annu Rev Biochem 76:167-193.
-
(2007)
Annu Rev Biochem
, vol.76
, pp. 167-193
-
-
Sharon, M.1
Robinson, C.V.2
-
26
-
-
76649084269
-
Quaternary dynamics and plasticity underlie small heat shock protein chaperone function
-
Stengel F, et al. (2010) Quaternary dynamics and plasticity underlie small heat shock protein chaperone function. Proc Natl Acad Sci USA 107:2007-2012.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 2007-2012
-
-
Stengel, F.1
-
27
-
-
34347228701
-
Determining the stoichiometry and interactions of macromolecular assemblies from mass spectrometry
-
DOI 10.1038/nprot.2007.73, PII NPROT.2007.73
-
Hernandez H, Robinson CV (2007) Determining the stoichiometry and interactions of macromolecular assemblies from mass spectrometry. Nat Protoc 2:715-726. (Pubitemid 47040033)
-
(2007)
Nature Protocols
, vol.2
, Issue.3
, pp. 715-726
-
-
Hernandez, H.1
Robinson, C.V.2
-
28
-
-
79551666466
-
N-terminal domain of human Hsp90 triggers binding to the cochaperone p23
-
Karagoz GE, et al. (2011) N-terminal domain of human Hsp90 triggers binding to the cochaperone p23. Proc Natl Acad Sci USA 108:580-585.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 580-585
-
-
Karagoz, G.E.1
-
29
-
-
0036303385
-
Stimulation of the weak ATPase activity of human Hsp90 by a client protein
-
DOI 10.1006/jmbi.2001.5245
-
McLaughlin SH, Smith HW, Jackson SE (2002) Stimulation of the weak ATPase activity of human Hsp90 by a client protein. J Mol Biol 315:787-798. (Pubitemid 34729326)
-
(2002)
Journal of Molecular Biology
, vol.315
, Issue.4
, pp. 787-798
-
-
McLaughlin, S.H.1
Smith, H.W.2
Jackson, S.E.3
-
30
-
-
7944225978
-
Independent ATPase activity of Hsp90 subunits creates a flexible assembly platform
-
DOI 10.1016/j.jmb.2004.09.055, PII S0022283604012112
-
McLaughlin SH, Ventouras LA, Lobbezoo B, Jackson SE (2004) Independent ATPase activity of Hsp90 subunits creates a flexible assembly platform. J Mol Biol 344:813-826. (Pubitemid 39469222)
-
(2004)
Journal of Molecular Biology
, vol.344
, Issue.3
, pp. 813-826
-
-
McLaughlin, S.H.1
Ventouras, L.-A.2
Lobbezoo, B.3
Jackson, S.E.4
-
31
-
-
0031444238
-
Identification and structural characterization of the ATP/ADP-binding site in the Hsp90 molecular chaperone
-
DOI 10.1016/S0092-8674(00)80314-1
-
Prodromou C, et al. (1997) Identification and structural characterization of the ATP/ ADP-binding site in the Hsp90 molecular chaperone. Cell 90:65-75. (Pubitemid 28009419)
-
(1997)
Cell
, vol.90
, Issue.1
, pp. 65-75
-
-
Prodromou, C.1
Roe, S.M.2
O'Brien, R.3
Ladbury, J.E.4
Piper, P.W.5
Pearl, L.H.6
-
32
-
-
70349690170
-
Isoforms of U1-70k control subunit dynamics in the human spliceosomal U1 snRNP
-
Hernandez H, et al. (2009) Isoforms of U1-70k control subunit dynamics in the human spliceosomal U1 snRNP. PLoS One 4:e7202.
-
(2009)
PLoS One
, vol.4
-
-
Hernandez, H.1
-
33
-
-
78651245123
-
Mass spectrometry reveals stable modules in holo and apo RNA polymerases I and III
-
Lane LA, et al. (2011) Mass spectrometry reveals stable modules in holo and apo RNA polymerases I and III. Structure 19:90-100.
-
(2011)
Structure
, vol.19
, pp. 90-100
-
-
Lane, L.A.1
-
34
-
-
34249041590
-
Definition of the minimal fragments of Sti1 required for dimerization, interaction with Hsp70 and Hsp90 and in vivo functions
-
DOI 10.1042/BJ20070084
-
Flom G, Behal RH, Rosen L, Cole DG, Johnson JL (2007) Definition of the minimal fragments of Sti1 required for dimerization, interaction with Hsp70 and Hsp90 and in vivo functions. Biochem J 404:159-167. (Pubitemid 46788096)
-
(2007)
Biochemical Journal
, vol.404
, Issue.1
, pp. 159-167
-
-
Flom, G.1
Behal, R.H.2
Rosen, L.3
Cole, D.G.4
Johnson, J.L.5
-
35
-
-
75149171461
-
HOP is a monomer: Investigation of the oligomeric state of the co-chaperone Hop
-
Yi F, Doudevski I, Regan L (2010) HOP is a monomer: investigation of the oligomeric state of the co-chaperone Hop. Protein Sci 19:19-25.
-
(2010)
Protein Sci
, vol.19
, pp. 19-25
-
-
Yi, F.1
Doudevski, I.2
Regan, L.3
-
37
-
-
79959344309
-
Client-loading conformation of the Hsp90 molecular chaperone revealed in the Cryo-EM structure of the human Hsp90:Hop complex
-
Southworth DR, Agard DA (2011) Client-loading conformation of the Hsp90 molecular chaperone revealed in the Cryo-EM structure of the human Hsp90:Hop complex.Mol Cell 42:771-781.
-
(2011)
Mol Cell
, vol.42
, pp. 771-781
-
-
Southworth, D.R.1
Agard, D.A.2
-
39
-
-
33646143013
-
Ligand binding by TPR domains
-
Cortajarena AL, Regan L (2006) Ligand binding by TPR domains. Protein Sci 15:1193-1198.
-
(2006)
Protein Sci
, vol.15
, pp. 1193-1198
-
-
Cortajarena, A.L.1
Regan, L.2
-
40
-
-
0034968225
-
Functional analysis of the Hsp90-associated human peptidyl prolyl cis/trans isomerases FKBP51, FKBP52 and Cyp40
-
DOI 10.1006/jmbi.2001.4595
-
Pirkl F, Buchner J (2001) Functional analysis of the Hsp90-associated human peptidyl prolyl Cis/Trans isomerases FKBP51, FKBP52 and cyp40. J Mol Biol 308:795-806. (Pubitemid 32568474)
-
(2001)
Journal of Molecular Biology
, vol.308
, Issue.4
, pp. 795-806
-
-
Pirkl, F.1
Buchner, J.2
-
41
-
-
0032488906
-
Hop modulates hsp70/hsp90 interactions in protein folding
-
DOI 10.1074/jbc.273.6.3679
-
Johnson BD, Schumacher RJ, Ross ED, Toft DO (1998) Hop modulates hsp70/hsp90 interactions in protein folding. J Biol Chem 273:3679-3686. (Pubitemid 28109795)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.6
, pp. 3679-3686
-
-
Johnson, B.D.1
Schumacher, R.J.2
Ross, E.D.3
Toft, D.O.4
-
42
-
-
0037830586
-
Sti1 is a novel activator of the Ssa proteins
-
DOI 10.1074/jbc.M301548200
-
Wegele H, Haslbeck M, Reinstein J, Buchner J (2003) Sti1 is a novel activator of the Ssa proteins. J Biol Chem 278:25970-25976. (Pubitemid 36835362)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.28
, pp. 25970-25976
-
-
Wegele, H.1
Haslbeck, M.2
Reinstein, J.3
Buchner, J.4
-
43
-
-
77956144557
-
Balance between folding and degradation for Hsp90-dependent client proteins: A key role for CHIP
-
Kundrat L, Regan L (2010) Balance between folding and degradation for Hsp90-dependent client proteins: a key role for CHIP. Biochemistry 49:7428-7438.
-
(2010)
Biochemistry
, vol.49
, pp. 7428-7438
-
-
Kundrat, L.1
Regan, L.2
-
44
-
-
0142215475
-
Global analysis of protein expression in yeast
-
DOI 10.1038/nature02046
-
Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425:737-741. (Pubitemid 37314318)
-
(2003)
Nature
, vol.425
, Issue.6959
, pp. 737-741
-
-
Ghaemmaghami, S.1
Huh, W.-K.2
Bower, K.3
Howson, R.W.4
Belle, A.5
Dephoure, N.6
O'Shea, E.K.7
Weissman, J.S.8
-
45
-
-
33746099650
-
Protein aggregation in crowded environments
-
DOI 10.1515/BC.2006.064, PII BCHM3875485
-
Ellis RJ, Minton AP (2006) Protein aggregation in crowded environments. Biol Chem 387:485-497. (Pubitemid 44071450)
-
(2006)
Biological Chemistry
, vol.387
, Issue.5
, pp. 485-497
-
-
Ellis, R.J.1
Minton, A.P.2
-
46
-
-
0037086063
-
A tandem mass spectrometer for improved transmission and analysis of large macromolecular assemblies
-
DOI 10.1021/ac0110552
-
Sobott F, Hernández H, McCammon MG, Tito MA, Robinson CV (2002) A tandem mass spectrometer for improved transmission and analysis of large macromolecular assemblies. Anal Chem 74:1402-1407. (Pubitemid 34233333)
-
(2002)
Analytical Chemistry
, vol.74
, Issue.6
, pp. 1402-1407
-
-
Sobott, F.1
Hernandez, H.2
McCammon, M.G.3
Tito, M.A.4
Robinson, C.V.5
|