-
2
-
-
61349116156
-
EORTC-GU group expert opinion on metastatic renal cell cancer
-
de Reijke T.M., Bellmunt J., van Poppel H., et al. EORTC-GU group expert opinion on metastatic renal cell cancer. Eur J Cancer 2009, 45:765-773.
-
(2009)
Eur J Cancer
, vol.45
, pp. 765-773
-
-
de Reijke, T.M.1
Bellmunt, J.2
van Poppel, H.3
-
3
-
-
67650327598
-
Metastatic renal cell carcinoma: Many treatment options, one patient
-
Rini B.I. Metastatic renal cell carcinoma: Many treatment options, one patient. J Clin Oncol 2009, 27:3225-3234.
-
(2009)
J Clin Oncol
, vol.27
, pp. 3225-3234
-
-
Rini, B.I.1
-
5
-
-
0033128165
-
Indirubin, the active constituent of a Chinese antileukemia medicine, inhibits cyclin-dependent kinases
-
Hoessel R., Leclerc S., Endicott J.A., et al. Indirubin, the active constituent of a Chinese antileukemia medicine, inhibits cyclin-dependent kinases. Nat Cell Biol 1999, 1:60-67.
-
(1999)
Nat Cell Biol
, vol.1
, pp. 60-67
-
-
Hoessel, R.1
Leclerc, S.2
Endicott, J.A.3
-
6
-
-
41949127664
-
Critical role of Bid and Bax in indirubin-3'-monoxime-induced apoptosis in human cancer cells
-
Shi J., Shen H.M. Critical role of Bid and Bax in indirubin-3'-monoxime-induced apoptosis in human cancer cells. Biochem Pharmacol 2008, 75:1729-1742.
-
(2008)
Biochem Pharmacol
, vol.75
, pp. 1729-1742
-
-
Shi, J.1
Shen, H.M.2
-
7
-
-
33846279781
-
Antitumor activity of novel indirubin derivatives in rat tumor model
-
Kim S.A., Kim Y.C., Kim S.W., et al. Antitumor activity of novel indirubin derivatives in rat tumor model. Clin Cancer Res 2007, 13:253-259.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 253-259
-
-
Kim, S.A.1
Kim, Y.C.2
Kim, S.W.3
-
8
-
-
33745594039
-
Indirubin-3'-monoxime, a CDK inhibitor induces growth inhibition and apoptosis-independent up-regulation of survivin in transitional cell cancer
-
Perabo F.G., Frossler C., Landwehrs G., et al. Indirubin-3'-monoxime, a CDK inhibitor induces growth inhibition and apoptosis-independent up-regulation of survivin in transitional cell cancer. Anticancer Res 2006, 26:2129-2135.
-
(2006)
Anticancer Res
, vol.26
, pp. 2129-2135
-
-
Perabo, F.G.1
Frossler, C.2
Landwehrs, G.3
-
9
-
-
33747698455
-
Indirubin enhances tumor necrosis factor-induced apoptosis through modulation of nuclear factor-κB signaling pathway
-
Sethi G., Ahn K.S., Sandur S.K., et al. Indirubin enhances tumor necrosis factor-induced apoptosis through modulation of nuclear factor-κB signaling pathway. J Biol Chem 2006, 281:23425-23435.
-
(2006)
J Biol Chem
, vol.281
, pp. 23425-23435
-
-
Sethi, G.1
Ahn, K.S.2
Sandur, S.K.3
-
10
-
-
27744489247
-
Synthesis and structure-activity relationships of novel indirubin derivatives as potent anti-proliferative agents with CDK2 inhibitory activities
-
Moon M.J., Lee S.K., Lee J.W., et al. Synthesis and structure-activity relationships of novel indirubin derivatives as potent anti-proliferative agents with CDK2 inhibitory activities. Bioorg Med Chem 2006, 14:237-246.
-
(2006)
Bioorg Med Chem
, vol.14
, pp. 237-246
-
-
Moon, M.J.1
Lee, S.K.2
Lee, J.W.3
-
11
-
-
27244457784
-
Indirubin, a Chinese anti-leukaemia drug, promotes neutrophilic differentiation of human myelocytic leukaemia HL-60 cells
-
Suzuki K., Adachi R., Hirayama A., et al. Indirubin, a Chinese anti-leukaemia drug, promotes neutrophilic differentiation of human myelocytic leukaemia HL-60 cells. Br J Haematol 2005, 130:681-690.
-
(2005)
Br J Haematol
, vol.130
, pp. 681-690
-
-
Suzuki, K.1
Adachi, R.2
Hirayama, A.3
-
12
-
-
23244449448
-
Induction of apoptosis by a novel indirubin-5-nitro-3'-monoxime, a CDK inhibitor, in human lung cancer cells
-
Lee J.W., Moon M.J., Min H.Y., et al. Induction of apoptosis by a novel indirubin-5-nitro-3'-monoxime, a CDK inhibitor, in human lung cancer cells. Bioorg Med Chem Lett 2005, 15:3948-3952.
-
(2005)
Bioorg Med Chem Lett
, vol.15
, pp. 3948-3952
-
-
Lee, J.W.1
Moon, M.J.2
Min, H.Y.3
-
13
-
-
20944435625
-
Indirubin derivatives inhibit Stat3 signaling and induce apoptosis in human cancer cells
-
Nam S., Buettner R., Turkson J., et al. Indirubin derivatives inhibit Stat3 signaling and induce apoptosis in human cancer cells. Proc Natl Acad Sci USA 2005, 102:5998-6003.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 5998-6003
-
-
Nam, S.1
Buettner, R.2
Turkson, J.3
-
14
-
-
16644361991
-
Novel indirubin derivatives, promising anti-tumor agents inhibiting cyclin-dependent kinases
-
Merz K.H., Schwahn S., Hippe F., et al. Novel indirubin derivatives, promising anti-tumor agents inhibiting cyclin-dependent kinases. Int J Clin Pharmacol Ther 2004, 42:656-658.
-
(2004)
Int J Clin Pharmacol Ther
, vol.42
, pp. 656-658
-
-
Merz, K.H.1
Schwahn, S.2
Hippe, F.3
-
15
-
-
8644224855
-
Molecular mechanisms of indirubin and its derivatives: Novel anticancer molecules with their origin in traditional Chinese phytomedicine
-
Eisenbrand G., Hippe F., Jakobs S., et al. Molecular mechanisms of indirubin and its derivatives: Novel anticancer molecules with their origin in traditional Chinese phytomedicine. J Cancer Res Clin Oncol 2004, 130:627-635.
-
(2004)
J Cancer Res Clin Oncol
, vol.130
, pp. 627-635
-
-
Eisenbrand, G.1
Hippe, F.2
Jakobs, S.3
-
16
-
-
0015759232
-
In vitro cultivation of human tumors: Establishment of cell lines derived from a series of solid tumors
-
Giard D.J., Aaronson S.A., Todaro G.J., et al. In vitro cultivation of human tumors: Establishment of cell lines derived from a series of solid tumors. J Natl Cancer Inst 1973, 51:1417-1423.
-
(1973)
J Natl Cancer Inst
, vol.51
, pp. 1417-1423
-
-
Giard, D.J.1
Aaronson, S.A.2
Todaro, G.J.3
-
17
-
-
0017412603
-
One hundred twenty-seven cultured human tumor cell lines producing tumors in nude mice
-
Fogh J., Fogh J.M., Orfeo T. One hundred twenty-seven cultured human tumor cell lines producing tumors in nude mice. J Natl Cancer Inst 1977, 59:221-226.
-
(1977)
J Natl Cancer Inst
, vol.59
, pp. 221-226
-
-
Fogh, J.1
Fogh, J.M.2
Orfeo, T.3
-
18
-
-
0034282515
-
Effects of PTK787/ZK 222584, a specific inhibitor of vascular endothelial growth factor receptor tyrosine kinases, on primary tumor, metastasis, vessel density, and blood flow in a murine renal cell carcinoma model
-
Drevs J., Hofmann I., Hugenschmidt H., et al. Effects of PTK787/ZK 222584, a specific inhibitor of vascular endothelial growth factor receptor tyrosine kinases, on primary tumor, metastasis, vessel density, and blood flow in a murine renal cell carcinoma model. Cancer Res 2000, 60:4819-4824.
-
(2000)
Cancer Res
, vol.60
, pp. 4819-4824
-
-
Drevs, J.1
Hofmann, I.2
Hugenschmidt, H.3
-
19
-
-
0036001196
-
Immunohistochemical localization of the IAP protein survivin in bladder mucosa and transitional cell carcinoma
-
Lehner R., Lucia M.S., Jarboe E.A., et al. Immunohistochemical localization of the IAP protein survivin in bladder mucosa and transitional cell carcinoma. Appl Immunohistochem Mol Morphol 2002, 10:134-138.
-
(2002)
Appl Immunohistochem Mol Morphol
, vol.10
, pp. 134-138
-
-
Lehner, R.1
Lucia, M.S.2
Jarboe, E.A.3
-
20
-
-
0035147448
-
Inhibition of cyclin-dependent kinase 1 (CDK1) by indirubin derivatives in human tumour cells
-
Marko D., Schatzle S., Friedel A., et al. Inhibition of cyclin-dependent kinase 1 (CDK1) by indirubin derivatives in human tumour cells. Br J Cancer 2001, 84:283-289.
-
(2001)
Br J Cancer
, vol.84
, pp. 283-289
-
-
Marko, D.1
Schatzle, S.2
Friedel, A.3
-
21
-
-
0035963318
-
Antimitotic properties of indirubin-3'-monoxime, a CDK/GSK-3 inhibitor: Induction of endoreplication following prophase arrest
-
Damiens E., Baratte B., Marie D., et al. Antimitotic properties of indirubin-3'-monoxime, a CDK/GSK-3 inhibitor: Induction of endoreplication following prophase arrest. Oncogene 2001, 20:3786-3797.
-
(2001)
Oncogene
, vol.20
, pp. 3786-3797
-
-
Damiens, E.1
Baratte, B.2
Marie, D.3
-
22
-
-
1642444921
-
[Clinical and experimental studies in the treatment of chronic granulocytic leukemia with indirubin (author's translation)]
-
[Clinical and experimental studies in the treatment of chronic granulocytic leukemia with indirubin (author's translation)]. Zhonghua Nei Ke Za Zhi 1979, 18:83-88.
-
(1979)
Zhonghua Nei Ke Za Zhi
, vol.18
, pp. 83-88
-
-
-
23
-
-
0019030222
-
[Studies on the mechanism of indirubin action in the treatment of chronic granulocytic leukemia. II. Effects of indirubin on nucleic acid and protein synthesis in animal transplantable tumor cells and normal proliferating cells in vitro (author's translation)]
-
Wu G.Y., Fang F.D. [Studies on the mechanism of indirubin action in the treatment of chronic granulocytic leukemia. II. Effects of indirubin on nucleic acid and protein synthesis in animal transplantable tumor cells and normal proliferating cells in vitro (author's translation)]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao 1980, 2:83-87.
-
(1980)
Zhongguo Yi Xue Ke Xue Yuan Xue Bao
, vol.2
, pp. 83-87
-
-
Wu, G.Y.1
Fang, F.D.2
-
24
-
-
0006019541
-
[Studies on the antineoplastic action and toxicity of synthetic indirubin (author's translation)]
-
Ji X.J., Zhang F.R., Lei J.L., Xu Y.T. [Studies on the antineoplastic action and toxicity of synthetic indirubin (author's translation)]. Yao Xue Xue Bao 1981, 16:146-148.
-
(1981)
Yao Xue Xue Bao
, vol.16
, pp. 146-148
-
-
Ji, X.J.1
Zhang, F.R.2
Lei, J.L.3
Xu, Y.T.4
-
25
-
-
0019774928
-
[Effect of indirubin on hemopoietic cell production (author's translation)]
-
Wan J.H., You Y.C., Mi J.X., et al. [Effect of indirubin on hemopoietic cell production (author's translation)]. Zhongguo Yao Li Xue Bao 1981, 2:241-244.
-
(1981)
Zhongguo Yao Li Xue Bao
, vol.2
, pp. 241-244
-
-
Wan, J.H.1
You, Y.C.2
Mi, J.X.3
-
26
-
-
0020198226
-
Studies on the mechanism of indirubin action in the treatment of chronic granulocytic leukemia. V. Binding between indirubin and DNA and identification of the type of binding
-
Wu G.Y., Liu J.Z., Fang F.D., et al. Studies on the mechanism of indirubin action in the treatment of chronic granulocytic leukemia. V. Binding between indirubin and DNA and identification of the type of binding. Sci Sin [B] 1982, 25:1071-1079.
-
(1982)
Sci Sin [B]
, vol.25
, pp. 1071-1079
-
-
Wu, G.Y.1
Liu, J.Z.2
Fang, F.D.3
-
27
-
-
0022149899
-
[Potential antileukemic agents, synthesis of derivatives of indirubin, indigo, and isoindigotin]
-
Wu K.M., Zhang M.Y., Fang Z., et al. [Potential antileukemic agents, synthesis of derivatives of indirubin, indigo, and isoindigotin]. Yao Xue Xue Bao 1985, 20:821-826.
-
(1985)
Yao Xue Xue Bao
, vol.20
, pp. 821-826
-
-
Wu, K.M.1
Zhang, M.Y.2
Fang, Z.3
-
28
-
-
0000721276
-
Studies on the mechanism of indirubin action in the treatment of chronic myelocytic leukemia (CML)
-
Gan W.J., Yang T., Wen S., et al. Studies on the mechanism of indirubin action in the treatment of chronic myelocytic leukemia (CML). Chin Acad Med Sci Beijing 1985, 611-613.
-
(1985)
Chin Acad Med Sci Beijing
, pp. 611-613
-
-
Gan, W.J.1
Yang, T.2
Wen, S.3
-
29
-
-
0033168929
-
The cancer anti-apoptosis mouse survivin gene: Characterization of locus and transcriptional requirements of basal and cell cycle-dependent expression
-
Li F., Altieri D.C. The cancer anti-apoptosis mouse survivin gene: Characterization of locus and transcriptional requirements of basal and cell cycle-dependent expression. Cancer Res 1999, 59:3143-3151.
-
(1999)
Cancer Res
, vol.59
, pp. 3143-3151
-
-
Li, F.1
Altieri, D.C.2
-
30
-
-
57049102388
-
Survivin expression in renal cell carcinoma
-
Zamparese R., Pannone G., Santoro A., et al. Survivin expression in renal cell carcinoma. Cancer Invest 2008, 26:929-935.
-
(2008)
Cancer Invest
, vol.26
, pp. 929-935
-
-
Zamparese, R.1
Pannone, G.2
Santoro, A.3
-
31
-
-
36349015992
-
The tumor gene survivin is highly expressed in adult renal tubular cells: Implications for a pathophysiological role in the kidney
-
Lechler P., Wu X., Bernhardt W., et al. The tumor gene survivin is highly expressed in adult renal tubular cells: Implications for a pathophysiological role in the kidney. Am J Pathol 2007, 171:1483-1498.
-
(2007)
Am J Pathol
, vol.171
, pp. 1483-1498
-
-
Lechler, P.1
Wu, X.2
Bernhardt, W.3
-
32
-
-
34250209885
-
Survivin and b7-h1 are collaborative predictors of survival and represent potential therapeutic targets for patients with renal cell carcinoma
-
Krambeck A.E., Dong H., Thompson R.H., et al. Survivin and b7-h1 are collaborative predictors of survival and represent potential therapeutic targets for patients with renal cell carcinoma. Clin Cancer Res 2007, 13:1749-1756.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 1749-1756
-
-
Krambeck, A.E.1
Dong, H.2
Thompson, R.H.3
-
33
-
-
33846519318
-
Expression of survivin in renal cell carcinomas: Association with pathologic features and clinical outcome
-
Byun S.S., Yeo W.G., Lee S.E., et al. Expression of survivin in renal cell carcinomas: Association with pathologic features and clinical outcome. Urology 2007, 69:34-37.
-
(2007)
Urology
, vol.69
, pp. 34-37
-
-
Byun, S.S.1
Yeo, W.G.2
Lee, S.E.3
-
34
-
-
33744777482
-
Survivin associates with cell proliferation in renal cancer cells: Regulation of survivin expression by insulin-like growth factor-1, interferon-γ and a novel NF- κB inhibitor
-
Sato A., Oya M., Ito K., et al. Survivin associates with cell proliferation in renal cancer cells: Regulation of survivin expression by insulin-like growth factor-1, interferon-γ and a novel NF- κB inhibitor. Int J Oncol 2006, 28:841-846.
-
(2006)
Int J Oncol
, vol.28
, pp. 841-846
-
-
Sato, A.1
Oya, M.2
Ito, K.3
-
35
-
-
0036643519
-
Distinct in vivo expression patterns of survivin splice variants in renal cell carcinomas
-
Mahotka C., Krieg T., Krieg A., et al. Distinct in vivo expression patterns of survivin splice variants in renal cell carcinomas. Int J Cancer 2002, 100:30-36.
-
(2002)
Int J Cancer
, vol.100
, pp. 30-36
-
-
Mahotka, C.1
Krieg, T.2
Krieg, A.3
|