Acute visual neglect and extinction: Distinct functional state of the visuospatial attention system

Brain

Volumn 134, Issue 11, 2011, Pages 3310-3325

  Umarova, Roza M ^a   Saur, Dorothee ^a,b   Kaller, Christoph P ^a   Vry, Magnus Sebastian ^a   Glauche, Volkmar ^a   Mader, Irina ^a   Hennig, Jürgen ^a   Weiller, Cornelius ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

^b UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

extinction; neglect; parietal hyperactivation; visuospatial attention

Indexed keywords

ADULT; AGED; ARTICLE; BRAIN REGION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; MALE; MIDDLE CEREBRAL ARTERY; NUCLEAR MAGNETIC RESONANCE IMAGING; OCCIPITAL CORTEX; PARIETAL CORTEX; PREFRONTAL CORTEX; PRIORITY JOURNAL; RIGHT HEMISPHERE; STROKE; VISION; VISUAL DEPRIVATION; VISUAL DISORDER; VISUAL FIELD;

EID: 81055133569     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/awr220     Document Type: Article

References (92)

1. Ashburner J, Friston KJ. Unified segmentation. Neuroimage 2005; 26: 839-51. (Pubitemid 40825026)
2. Baron JC. Depression of energy metabolism in distant brain structures: studies with positron emission tomography in stroke patients. Semin Neurol 1989; 9: 281-5. (Pubitemid 20081692)
3. Bartolomeo P, Chokron S. Left unilateral neglect or right hyperattention? Neurology 1999; 53: 2023-7.
4. Bartolomeo P, Thiebaut de Schotten M, Doricchi F. Left unilateral neglect as a disconnection syndrome. Cereb Cortex 2007; 17: 2479-90. (Pubitemid 47537832)
5. Beis JM, Keller C, Morin N, Bartolomeo P, Bernati T, Chokron S, et al. Right spatial neglect after left hemisphere stroke: qualitative and quantitative study. Neurology 2004; 63: 1600-5. (Pubitemid 39507575)
6. Bestmann S, Swayne O, Blankenburg F, Ruff CC, Teo J, Weiskopf N, et al. The role of contralesional dorsal premotor cortex after stroke as studied with concurrent TMS-fMRI. J Neurosci 2010; 30: 11926-37.
7. Bird CM, Malhotra P, Parton A, Coulthard E, Rushworth MF, Husain M. Visual neglect after right posterior cerebral artery infarction. J Neurol Neurosurg Psychiatry 2006; 77: 1008-12. (Pubitemid 44338518)
8. Bogousslavsky J, Miklossy J, Regli F, Deruaz JP, Assal G, Delaloye B. Subcortical neglect: neuropsychological, SPECT, and neuropathological correlations with anterior choroidal artery territory infarction. Ann Neurol 1988; 23: 448-52.
9. Brain WR. Visual diisorientation with special reference to lesions of the right cerebral hemisphere. Brain 1941; 64: 273-90.
10. Buchel C, Josephs O, Rees G, Turner R, Frith CD, Friston KJ. The functional anatomy of attention to visual motion. A functional MRI study. Brain 1998; 121: 1281-94. (Pubitemid 28327405)
11. Buxbaum LJ, Ferraro MK, Veramonti T, Farne A, Whyte J, Ladavas E, et al. Hemispatial neglect: Subtypes, neuroanatomy, and disability. Neurology 2004; 62: 749-56. (Pubitemid 38298951)
12. Cicek M, Gitelman D, Hurley RS, Nobre A, Mesulam M. Anatomical physiology of spatial extinction. Cereb Cortex 2007; 17: 2892-8. (Pubitemid 350129445)
13. Committeri G, Pitzalis S, Galati G, Patria F, Pelle G, Sabatini U, et al. Neural bases of personal and extrapersonal neglect in humans. Brain 2007; 130: 431-41. (Pubitemid 46181096)
14. Corbetta M, Kincade MJ, Lewis C, Snyder AZ, Sapir A. Neural basis and recovery of spatial attention deficits in spatial neglect. Nat Neurosci 2005; 8: 1603-10. (Pubitemid 41573676)
15. Corbetta M, Kincade JM, Ollinger JM, McAvoy MP, Shulman GL. Voluntary orienting is dissociated from target detection in human posterior parietal cortex. Nat Neurosci 2000; 3: 292-7. (Pubitemid 30140793)
16. Corbetta M, Shulman GL. Control of goal-directed and stimulus-driven attention in the brain. Nat Rev Neurosci 2002; 3: 201-15. (Pubitemid 135706590)
17. Critchley M. The phenomenon of tactile inattention with special reference to parietal lesions. Brain 1949; 72: 538-61.
18. Crinion J, Ashburner J, Leff A, Brett M, Price C, Friston K. Spatial normalization of lesioned brains: performance evaluation and impact on fMRI analysis. Neuroimage 2007; 37: 866-75. (Pubitemid 47248302)
19. Doricchi F, Thiebaut de Schotten M, Tomaiuolo F, Bartolomeo P. White matter (dis)connections and gray matter (dys)functions in visual neglect: gaining insights into the brain networks of spatial awareness. Cortex 2008; 44: 983-95.
20. Driver J, Mattingley JB. Parietal neglect and visual awareness. Nat Neurosci 1998; 1: 17-22. (Pubitemid 128652636)
21. Driver J, Vuilleumier P, Eimer M, Rees G. Functional magnetic resonance imaging and evoked potential correlates of conscious and unconscious vision in parietal extinction patients. Neuroimage 2001; 14: S68-75. (Pubitemid 32554532)
22. Eickhoff SB, Stephan KE, Mohlberg H, Grefkes C, Fink GR, Amunts K, et al. A new SPM toolbox for combining probabilistic cytoarchitectonic maps and functional imaging data. Neuroimage 2005; 25: 1325-35. (Pubitemid 40591672)
23. Ellis AW, Jordan JL, Sullivan CA. Unilateral neglect is not unilateral: evidence for additional neglect of extreme right space. Cortex 2006; 42: 861-8. (Pubitemid 46768741)
24. Friston K, Ashburner JT, Kiebel S, Nichols T, Penny W, editors. Statistical parametric mapping. The analysis of functional brain images. London: Academic Press; 2007. p. 647.
25. Gerloff C, Bushara K, Sailer A, Wassermann EM, Chen R, Matsuoka T, et al. Multimodal imaging of brain reorganization in motor areas of the contralesional hemisphere of well recovered patients after capsular stroke. Brain 2006; 129: 791-808. (Pubitemid 43278240)
26. Giessing C, Thiel CM, Stephan KE, Rosler F, Fink GR. Visuospatial attention: how to measure effects of infrequent, unattended events in a blocked stimulus design. Neuroimage 2004; 23: 1370-81. (Pubitemid 40260360)
27. Glascher J. Visualization of group inference data in functional neuroima-ging. Neuroinformatics 2009; 7: 73-82.
28. Gottesman RF, Kleinman JT, Davis C, Heidler-Gary J, Newhart M, Kannan V, et al. Unilateral neglect is more severe and common in older patients with right hemispheric stroke. Neurology 2008; 71: 1439-44.
29. Halligan PW, Fink GR, Marshall JC, Vallar G. Spatial cognition: evidence from visual neglect. Trends Cogn Sci 2003; 7: 125-33. (Pubitemid 36294173)
30. Hamzei F, Knab R, Weiller C, Rother J. The influence of extra-and intracranial artery disease on the BOLD signal in FMRI. Neuroimage 2003; 20: 1393-9. (Pubitemid 37268156)
31. Heilman KM, Van Den Abell T. Right hemisphere dominance for attention: the mechanism underlying hemispheric asymmetries of inattention (neglect). Neurology 1980; 30: 327-30. (Pubitemid 10133775)
32. Heilman K, Watson R, Valenstein E. Neglect and related disorders. In: Heilman K, Valenstein E, editors. Clinical neuropsychology. Oxford University Press; 2003. p. 296-346.
33. Hillis AE, Chang S, Heidler-Gary J, Newhart M, Kleinman JT, Davis C, et al. Neural correlates of modality-specific spatial extinction. J Cogn Neurosci 2006; 18: 1889-98. (Pubitemid 44674287)
34. Hillis AE, Newhart M, Heidler J, Barker PB, Herskovits EH, Degaonkar M. Anatomy of spatial attention: insights from perfusion imaging and hemispatial neglect in acute stroke. J Neurosci 2005; 25: 3161-7. (Pubitemid 40463551)
35. Husain M, Kennard C. Visual neglect associated with frontal lobe infarction. J Neurol 1996; 243: 652-7. (Pubitemid 26321011)
36. Husain M, Shapiro K, Martin J, Kennard C. Abnormal temporal dynamics of visual attention in spatial neglect patients. Nature 1997; 385: 154-6. (Pubitemid 27034215)
37. Jehkonen M, Laihosalo M, Kettunen JE. Impact of neglect on functional outcome after stroke: a review of methodological issues and recent research findings. Restor Neurol Neurosci 2006; 24: 209-15. (Pubitemid 44763323)
38. Johansen-Berg H, Rushworth MF, Bogdanovic MD, Kischka U, Wimalaratna S, Matthews PM. The role of ipsilateral premotor cortex in hand movement after stroke. Proc Natl Acad Sci USA 2002; 99: 14518-23. (Pubitemid 35257703)
39. Karnath HO, Ferber S, Himmelbach M. Spatial awareness is a function of the temporal not the posterior parietal lobe. Nature 2001; 411: 950-3. (Pubitemid 32601491)
40. Karnath HO, Fruhmann Berger M, Kuker W, Rorden C. The anatomy of spatial neglect based on voxelwise statistical analysis: a study of 140 patients. Cereb Cortex 2004; 14: 1164-72. (Pubitemid 39268905)
41. Karnath HO, Himmelbach M, Kuker W. The cortical substrate of visual extinction. Neuroreport 2003; 14: 437-42. (Pubitemid 36337946)
42. Kinsbourne M. A model for the mechanism of unilateral neglect of space. Trans Am Neurol Assoc 1970; 95: 143-6.
43. Koch G, Oliveri M, Cheeran B, Ruge D, Lo Gerfo E, Salerno S, et al. Hyperexcitability of parietal-motor functional connections in the intact left-hemisphere of patients with neglect. Brain 2008; 131: 3147-55.
44. Krug K. A common neuronal code for perceptual processes in visual cortex? Comparing choice and attentional correlates in V5/MT. Philos Trans R Soc Lond B Biol Sci 2004; 359: 929-41. (Pubitemid 38784081)
45. Liu TT. Efficiency, power, and entropy in event-related fMRI with multiple trial types. Part II: design of experiments. Neuroimage 2004; 21: 401-13. (Pubitemid 38115030)
46. Luaute J, Michel C, Rode G, Pisella L, Jacquin-Courtois S, Costes N, et al. Functional anatomy of the therapeutic effects of prism adaptation on left neglect. Neurology 2006; 66: 1859-67. (Pubitemid 44049817)
47. Lumer ED, Friston KJ, Rees G. Neural correlates of perceptual rivalry in the human brain. Science 1998; 280: 1930-4. (Pubitemid 28299399)
48. Lynch JC, McLaren JW. Deficits of visual attention and saccadic eye movements after lesions of parietooccipital cortex in monkeys. J Neurophysiol 1989; 61: 74-90. (Pubitemid 19038760)
49. Malhotra P, Jager HR, Parton A, Greenwood R, Playford ED, Brown MM, et al. Spatial working memory capacity in unilateral neglect. Brain 2005; 128: 424-35. (Pubitemid 40222611)
50. Marshall JW, Baker HF, Ridley RM. Contralesional neglect in monkeys with small unilateral parietal cortical ablations. Behav Brain Res 2002; 136: 257-65. (Pubitemid 35246411)
51. Mesulam MM. A cortical network for directed attention and unilateral neglect. Ann Neurol 1981; 10: 309-25. (Pubitemid 11027068)
52. Mesulam MM. Large-scale neurocognitive networks and distributed processing for attention, language, and memory. Ann Neurol 1990; 28: 597-613.
53. Monakow CV. Aphasie und diaschisis. Neurologisches Centralbaltt 1906; 25: 1026-38.
54. Mort DJ, Malhotra P, Mannan SK, Rorden C, Pambakian A, Kennard C, et al. The anatomy of visual neglect. Brain 2003; 126: 1986-97. (Pubitemid 37059438)
55. Musso M, Weiller C, Kiebel S, Muller SP, Bulau P, Rijntjes M. Training-induced brain plasticity in aphasia. Brain 1999; 122: 1781-90. (Pubitemid 29425680)
56. Payne BR, Lomber SG, Geeraerts S, van der Gucht E, Vandenbussche E. Reversible visual hemineglect. Proc Natl Acad Sci USA 1996; 93: 290-4. (Pubitemid 26038145)
57. Perry RJ, Zeki S. The neurology of saccades and covert shifts in spatial attention: an event-related fMRI study. Brain 2000; 123: 2273-88.
58. Posner MI, Walker JA, Friedrich FJ, Rafal RD. Effects of parietal injury on covert orienting of attention. J Neurosci 1984; 4: 1863-74. (Pubitemid 14055541)
59. Rees G, Wojciulik E, Clarke K, Husain M, Frith C, Driver J. Neural correlates of conscious and unconscious vision in parietal extinction. Neurocase 2002; 8: 387-93. (Pubitemid 36138840)
60. Rees G, Wojciulik E, Clarke K, Husain M, Frith C, Driver J. Unconscious activation of visual cortex in the damaged right hemisphere of a parietal patient with extinction. Brain 2000; 123: 1624-33. (Pubitemid 30481186)
61. Riecker A, Groschel K, Ackermann H, Schnaudigel S, Kassubek J, Kastrup A. The role of the unaffected hemisphere in motor recovery after stroke. Hum Brain Mapp 2010; 31: 1017-29.
62. Ringman JM, Saver JL, Woolson RF, Clarke WR, Adams HP. Frequency, risk factors, anatomy, and course of unilateral neglect in an acute stroke cohort. Neurology 2004; 63: 468-74. (Pubitemid 39031376)
63. Rorden C, Fruhmann Berger M, Karnath HO. Disturbed line bisection is associated with posterior brain lesions. Brain Res 2006; 1080: 17-25.
64. Saalmann YB, Pigarev IN, Vidyasagar TR. Neural mechanisms of visual attention: how top-down feedback highlights relevant locations. Science 2007; 316: 1612-5. (Pubitemid 46982033)
65. Saur D, Lange R, Baumgaertner A, Schraknepper V, Willmes K, Rijntjes M, et al. Dynamics of language reorganization after stroke. Brain 2006; 129: 1371-84. (Pubitemid 43999371)
66. Schaechter JD, Perdue KL. Enhanced cortical activation in the contrale-sional hemisphere of chronic stroke patients in response to motor skill challenge. Cereb Cortex 2008; 18: 638-47. (Pubitemid 351264234)
67. Shinoura N, Suzuki Y, Yamada R, Tabei Y, Saito K, Yagi K. Damage to the right superior longitudinal fasciculus in the inferior parietal lobe plays a role in spatial neglect. Neuropsychologia 2009; 47: 2600-3.
68. Stone SP, Halligan PW, Marshall JC, Greenwood RJ. Unilateral neglect: a common but heterogeneous syndrome. Neurology 1998; 50: 1902-5. (Pubitemid 28283282)
69. Thimm M, Fink GR, Sturm W. Neural correlates of recovery from acute hemispatial neglect. Restor Neurol Neurosci 2008; 26: 481-92.
70. Ticini LF, de Haan B, Klose U, Nagele T, Karnath HO. The role of temporo-parietal cortex in subcortical visual extinction. J Cogn Neurosci 2010; 22: 2141-50.
71. Treue S, Maunsell JH. Attentional modulation of visual motion processing in cortical areas MT and MST. Nature 1996; 382: 539-41. (Pubitemid 26260695)
72. Treue S, Maunsell JH. Effects of attention on the processing of motion in macaque middle temporal and medial superior temporal visual cortical areas. J Neurosci 1999; 19: 7591-602. (Pubitemid 29404615)
73. Umarova RM, Saur D, Schnell S, Kaller CP, Vry MS, Glauche V, et al. Structural connectivity for visuospatial attention: significance of ventral pathways. Cereb Cortex 2010; 20: 121-9.
74. Urbanski M, Thiebaut De Schotten M, Rodrigo S, Catani M, Oppenheim C, Touzé E. Brain networks of spatial awareness: Evidence from diffusion tensor imaging tractography. J Neurol Neurosurg Psychiatry 2008; 79: 598-601. (Pubitemid 351571884)
75. Vallar G. Extrapersonal visual unilateral spatial neglect and its neuroanat-omy. Neuroimage 2001; 14: S52-8. (Pubitemid 32554530)
76. Vallar G, Perani D. The anatomy of unilateral neglect after right-hemisphere stroke lesions. A clinical/CT-scan correlation study in man. Neuropsychologia 1986; 24: 609-22. (Pubitemid 17181136)
77. Vallar G, Rusconi ML, Bignamini L, Geminiani G, Perani D. Anatomical correlates of visual and tactile extinction in humans: a clinical CT scan study. J Neurol Neurosurg Psychiatry 1994; 57: 464-70. (Pubitemid 24118143)
78. Vandenberghe R, Geeraerts S, Molenberghs P, Lafosse C, Vandenbulcke M, Peeters K, et al. Attentional responses to unattended stimuli in human parietal cortex. Brain 2005; 128: 2843-57. (Pubitemid 41746638)
79. Verdon V, Schwartz S, Lovblad KO, Hauert CA, Vuilleumier P. Neuroanatomy of hemispatial neglect and its functional components: a study using voxel-based lesion-symptom mapping. Brain 2010; 133: 880-94.
80. Vossel S, Eschenbeck P, Weiss PH, Weidner R, Saliger J, Karbe H, et al. Visual extinction in relation to visuospatial neglect after right-hemispheric stroke: quantitative assessment and statistical lesion-symptom mapping. J Neurol Neurosurg Psychiatry 2011; 82: 862-8.
81. Vuilleumier PO, Rafal RD. A systematic study of visual extinction. Between-and within-field deficits of attention in hemispatial neglect. Brain 2000; 123: 1263-79. (Pubitemid 30312116)
82. Vuilleumier P, Armony JL, Clarke K, Husain M, Driver J, Dolan RJ. Neural response to emotional faces with and without awareness: event-related fMRI in a parietal patient with visual extinction and spatial neglect. Neuropsychologia 2002; 40: 2156-66.
83. Vuilleumier P, Sagiv N, Hazeltine E, Poldrack RA, Swick D, Rafal RD, et al. Neural fate of seen and unseen faces in visuospatial neglect: a combined event-related functional MRI and event-related potential study. Proc Natl Acad Sci USA 2001; 98: 3495-500. (Pubitemid 32220873)
84. Vuilleumier P, Schwartz S, Verdon V, Maravita A, Hutton C, Husain M, et al. Abnormal attentional modulation of retinotopic cortex in parietal patients with spatial neglect. Curr Biol 2008; 18: 1525-9.
85. Weiller C, Chollet F, Friston KJ, Wise RJ, Frackowiak RS. Functional reorganization of the brain in recovery from striatocapsular infarction in man. Ann Neurol 1992; 31: 463-72.
86. Weiller C, Isensee C, Rijntjes M, Huber W, Mü ller S, Bier D, et al. Recovery from Wernicke's aphasia: a positron emission tomographic study. Ann Neurol 1995; 37: 723-32.
87. Weiller C, Juptner M, Fellows S, Rijntjes M, Leonhardt G, Kiebel S, et al. Brain representation of active and passive movements. Neuroimage 1996; 4: 105-10. (Pubitemid 26337403)
88. Weiller C, Willmes K, Reiche W, Thron A, Isensee C, Buell U, et al. The case of aphasia or neglect after striatocapsular infarction. Brain 1993; 116: 1509-25. (Pubitemid 24038865)
89. Wilson B, Cockburn J, Haligan PW. Behavioural inattention test. Titchfield, Hants: Thames Valley Company; 1987.
90. Witt ST, Laird AR, Meyerand ME. Functional neuroimaging correlates of finger-tapping task variations: an ALE meta-analysis. Neuroimage 2008; 42: 343-56.
91. Zaitsev M, Dold C, Sakas G, Hennig J, Speck O. Magnetic resonance imaging of freely moving objects: prospective real-time motion correction using an external optical motion tracking system. Neuroimage 2006; 31: 1038-50. (Pubitemid 43851344)
92. Zaitsev M, Hennig J, Speck O. Point spread function mapping with parallel imaging techniques and high acceleration factors: fast, robust, and flexible method for echo-planar imaging distortion correction. Magn Reson Med 2004; 52: 1156-66. (Pubitemid 39453290)