Disordering of human telomeric G-Quadruplex with novel antiproliferative anthrathiophenedione

PLoS ONE

Volumn 6, Issue 11, 2011, Pages

  Kaluzhny, Dmitry ^a   Ilyinsky, Nikolay ^b   Shchekotikhin, Andrei ^c   Sinkevich, Yuri ^d   Tsvetkov, Philipp O ^a   Tsvetkov, Vladimir ^e   Veselovsky, Alexander ^e   Livshits, Mikhail ^a   Borisova, Olga ^a   Shtil, Alexander ^f   Shchyolkina, Anna ^a  

^a ENGELHARDT INSTITUTE OF MOLECULAR BIOLOGY   (Russian Federation)

^b MOSCOW INSTITUTE OF PHYSICS AND TECHNOLOGY   (Russian Federation)

^c GAUSE INSTITUTE OF NEW ANTIBIOTICS   (Russian Federation)

^d MENDELEEV UNIVERSITY OF CHEMICAL TECHNOLOGY OF RUSSIA   (Russian Federation)

^e INSTITUTE OF BIOMEDICAL CHEMISTRY   (Russian Federation)

^f N N BLOKHIN RUSSIAN CANCER RESEARCH CENTER   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

4,11 BIS[[2 [(ACETIMIDO)AMINO]ETHYL]AMINO]ANTHRA[2,3 B]THIOPHENE 5,10 DIONE; ANTINEOPLASTIC AGENT; DNA; GUANINE QUADRUPLEX; OLIGONUCLEOTIDE; POTASSIUM ION; SODIUM ION; UNCLASSIFIED DRUG; 4,11 BIS((2 ((ACETIMIDO)AMINO)ETHYL)AMINO)ANTHRA(2,3 B)THIOPHENE 5,10 DIONE; 4,11-BIS((2-((ACETIMIDO)AMINO)ETHYL)AMINO)ANTHRA(2,3-B)THIOPHENE-5,10-DIONE; ANTHRAQUINONE DERIVATIVE; POTASSIUM; SODIUM; THIOPHENE DERIVATIVE;

ARTICLE; BINDING AFFINITY; CELL STRAIN HCT116; CHEMICAL INTERACTION; CIRCULAR DICHROISM; CONFORMATION; CONTROLLED STUDY; DNA STRUCTURE; DRUG CYTOTOXICITY; DRUG DNA BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; ISOTHERMAL TITRATION CALORIMETRY; LIGAND BINDING; MOLECULAR DYNAMICS; SIMULATION; THERMODYNAMICS; ULTRAVIOLET SPECTROSCOPY; CELL PROLIFERATION; CHEMICAL STRUCTURE; COLON TUMOR; DRUG EFFECT; GENETICS; LEUKEMIA; METABOLISM; SYNTHESIS; TELOMERE; TUMOR CELL CULTURE;

ANTHRAQUINONES; CELL PROLIFERATION; CIRCULAR DICHROISM; COLONIC NEOPLASMS; G-QUADRUPLEXES; HUMANS; LEUKEMIA; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; NUCLEIC ACID CONFORMATION; OLIGONUCLEOTIDES; POTASSIUM; SODIUM; TELOMERE; THIOPHENES; TUMOR CELLS, CULTURED;

EID: 81055129661     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0027151     Document Type: Article

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