Taking an integrated approach: Managing women with phytoestrogens

Climacteric

Volumn 14, Issue SUPPL. 2, 2011, Pages 2-7

  Panay, N ^a  

^a QUEEN CHARLOTTE S AND CHELSEA HOSPITAL   (United Kingdom)

Author keywords

complementary; hrt; isoflavones; Menopause; phytoestrogen; red clover; soy

Indexed keywords

CIMICIFUGA RACEMOSA EXTRACT; GINKGO BILOBA EXTRACT; GINSENG EXTRACT; HYPERICUM PERFORATUM EXTRACT; ISOFLAVONE DERIVATIVE; PHYTOESTROGEN; SEROTONIN UPTAKE INHIBITOR; WARFARIN;

ALTERNATIVE MEDICINE; ARTICLE; BONE DENSITY; BREAST; CARDIOVASCULAR DISEASE; DIET SUPPLEMENTATION; DIET THERAPY; DIZZINESS; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; ENDOMETRIUM; ENDOMETRIUM HYPERPLASIA; FEAR; FEMALE; GASTROINTESTINAL SYMPTOM; HEADACHE; HERB; HORMONE SUBSTITUTION; HOT FLUSH; HUMAN; HYPOTENSION; INFORMED CONSENT; LIFESTYLE MODIFICATION; LIMB PAIN; LIVER DYSFUNCTION; MENOPAUSAL SYNDROME; MENOPAUSE; OSTEOPOROSIS; OUTCOME ASSESSMENT; PATIENT COUNSELING; PRIORITY JOURNAL; PSYCHOLOGICAL ASPECT; RANDOMIZED CONTROLLED TRIAL (TOPIC); RATING SCALE; RED CLOVER; RISK BENEFIT ANALYSIS; SKIN ALLERGY; VASOMOTOR DISORDER; VOMITING;

BREAST; CARDIOVASCULAR DISEASES; COMPLEMENTARY THERAPIES; DIETARY SUPPLEMENTS; ENDOMETRIUM; FEMALE; HOT FLASHES; HUMANS; ISOFLAVONES; MENOPAUSE; OSTEOPOROSIS, POSTMENOPAUSAL; PHYTOESTROGENS; PHYTOTHERAPY; PLACEBOS; RANDOMIZED CONTROLLED TRIALS AS TOPIC; TRIFOLIUM;

EID: 81055124397     PISSN: 13697137     EISSN: 14730804     Source Type: Journal    
DOI: 10.3109/13697137.2011.626367     Document Type: Article

References (20)

1. Beck V, Unterrieder E, Krenn L, Kubelka W, Jungbauer A. Comparison of hormonal activity (estrogen, androgen and progestin) of standardized plant extracts for large scale use in hormone replacement therapy. J Steroid Biochem Mol Biol 2003; 84:259-68 (Pubitemid 36514843)
2. Dornstauder E, Jisa E, Unterrieder I, Krenn L, Kubelka W, Jungbauer A. Estrogenic activity of two standardized red clover extracts (Menoflavon) intended for large scale use in hormone replacement therapy. J Steroid Biochem Mol Biol 2001;78:67-75 (Pubitemid 32786788)
3. Clarke DB, Bailey V, Lloyd AS. Determination of phytoestrogens in dietary supplements by LC-MS/MS. Food Addit Contam Part A Chem Anal Control Expo Risk Assess 2008; 25:534-47 (Pubitemid 351910955)
4. Setchell KD, Brown NM, Lydeking-Olsen E. The clinical importance of the metabolite equol-a clue to the effectiveness of soy and its isoflavones. J Nutr 2002;132:3577-84 (Pubitemid 35435031)
5. Jeri AR. The use of an isoflavone supplement to relieve hot flushes. Female Patient 2002;27:47-9
6. van de Weijer PH, Barentsen R. Isoflavones from red clover (Promensil) significantly reduce menopausal hot flush symptoms compared with placebo. Maturitas 2002;42:187-93 (Pubitemid 34876810)
7. Hidalgo LA, Chedraui PA, Morocho N, Ross S, San Miguel G. The effect of red clover isoflavones on menopausal symptoms, lipids and vaginal cytology in menopausal women: a randomized, double-blind, placebo-controlled study. Gynecol Endocrinol 2005;21:257-64 (Pubitemid 43041746)
8. Coon JT, Pittler MH, Ernst E. Trifolium pratense isoflavones in the treatment of menopausal hot flushes: a systematic review and meta-analysis. Phytomedicine 2007;14:153-9 (Pubitemid 46136954)
9. Lipovac M, Chedraui P, Gruenhut C, et al . The effect of red clover isoflavone supplementation over vasomotor and menopausal symptoms in postmenopausal women. Gynecol Endocrinol 2011 Aug 26. Epub ahead of print
10. Atkinson C, Compston JE, Day NE, Dowsett M, Bingham SA. The effects of phytoestrogen isoflavones on bone density in women: a double-blind, randomized, placebo-controlled trial. Am J Clin Nutr 2004;79:326-33 (Pubitemid 41095988)
11. Clifton-Bligh PB, Baber RJ, Fulcher GR, Nery ML, Moreton T. The effect of isoflavones extracted from red clover (Rimostil) on lipid and bone metabolism. Menopause 2001;8:259-65 (Pubitemid 32645959)
12. Nestel PJ, Pomeroy S, Kay S, et al. Isoflavones from red clover improve systemic arterial compliance but not plasma lipids in menopausal women. J Clin Endocrinol Metab 1999;84:895-8 (Pubitemid 29138214)
13. Atkinson C, Warren RM, Sala E, et al. Red-clover-derived isoflavones and mammographic breast density: a double-blind, randomized, placebo-controlled trial [ISRCTN42940165]. Breast Cancer Res 2004;6:R170-9
14. Powles TJ, Howell A, Evans DG, et al. Red clover isoflavones are safe and well tolerated in women with a family history of breast cancer. Menopause Int 2008;14:6-12
15. Shu XO, Jin F, Dai Q, et al . Soyfood intake during adolescence and subsequent risk of breast cancer among Chinese women. Cancer Epidemiol Biomarkers Prev 2001;10:483-8 (Pubitemid 32701634)
16. Hale GE, Hughes CL, Robboy SJ, Agarwal SK, Bievre M. A double-blind randomized study on the effects of red clover isoflavones on the endometrium. Menopause 2001;8:338-46 (Pubitemid 32826166)
17. Imhof M, Gocan A, Reithmayr F, et al. Effects of a red clover extract (MF11RCE) on endometrium and sex hormones in postmenopausal women. Maturitas 2006;55:76-81 (Pubitemid 44109945)
18. Baber RJ, Templeman C, Morton T, Kelly GE, West L. Randomized placebo-controlled trial of an isoflavone supplement and menopausal symptoms in women. Climacteric 1999;2:85-92 (Pubitemid 29333647)
19. W oods R, Colville N, Blazquez J, et al. Effects of red clover isoflavones (Promensil) versus placebo on uterine endometrium, vaginal maturation index and the uterine artery in healthy postmenopausal women. J Br Menopause Soc 2003;S2:23
20. Lipovac M, Chedraui P, Gruenhut C, Gocan A, Stammler M, Imhof M. Improvement of postmenopausal depressive and anxiety symptoms after treatment with isoflavones derived from red clover extracts. Maturitas 2010;65:258-61