Randomized placebo-controlled trial of an isoflavone supplement and menopausal symptoms in women

Climacteric

Volumn 2, Issue 2, 1999, Pages 85-92

  Baber, R J ^a   Templeman, C ^a   Morton, T ^a   Kelly, G E ^b   West, L ^b  

^a UNIVERSITY OF SYDNEY   (Australia)

^b Novogen Ltd   (Australia)

Author keywords

Hot flushes; Isoflavones; Menopause; Randomized trial

Indexed keywords

ISOFLAVONE; ISOFLAVONE DERIVATIVE; SEX HORMONE BINDING GLOBULIN; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BLOOD LEVEL; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DIET SUPPLEMENTATION; DIETARY INTAKE; DRUG URINE LEVEL; FEMALE; HOT FLUSH; HUMAN; MAJOR CLINICAL STUDY; MENOPAUSAL SYNDROME; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SCORING SYSTEM; VAGINA MUCOSA;

EID: 0032816439     PISSN: 13697137     EISSN: None     Source Type: Journal    
DOI: 10.3109/13697139909025571     Document Type: Article

References (22)

1. Rekers H. Mastering the menopause. In Burger H, Boulet MJ, eds. A Portrait of the Menopause. Carnforth, UK: Parthenon Publishing, 1991: 23-43
2. Ismael NN. A study on the menopause in Malaysia. Maturitas 1994;19:205-9
3. Tang GW. The climacteric of Chinese factory workers. Maturitas 1994;19:177-82
4. Guthrie JR, Dennerstein L, Hopper JL, Burger HG. Hot flushes, menstrual status, and hormone levels in a populatio-based sample of midlife women. Obstet Gynecol 1996;88:437-42
5. Miksicek RJ. Interaction of naturally occurring nonsteroidal estrogens with expressed recombinant human estrogen receptor. J Steroid Biochem Mol Biol 1994;49:153-60
6. Collins BM, McLachlan JA, Arnold SF. The estrogenic and antiestrogenic activities of phytochemicals with human estrogen receptor expressed in yeast. Steroids 1997;62:365-72
7. Adlercreutz H, Honjo H, Higashi A, et al. Urinary excretion of lignans and isoflavonoid phytoestrogens in Japanese men and women consuming a traditional Japanese diet. Am J Clin Nutr 1991;54:1093-100
8. Price KR, Fenwick GR. Naturally occurring oestrogens in foods - a review. Food Addit Contam 1985;2:73-106
9. Adlercreutz H, Mazur W. Phyto-oestrogens and Western diseases. Ann Med 1997;29:95-120
10. Goldin BR, Adlercreutz H, Gorbach SL, et al. The relationship between estrogen levels and diets of Caucasian American and Oriental immigrant women. Am J Clin Nutr 1986;44:945-53
11. Albertazzi P, Pansini F, Bonaccorsi G, Zanotti L, Forini E, De Aloysio D. The effect of dietary soy supplementation on hot flushes. Obstet Gynecol 1998;91:6-11
12. Greene JG. A factor analytic study of climacteric symptoms. J Psychosom Res 1976;20:425-30
13. Setchell KD, Welsh MB, Lim CK. High-performance liquid chromatographic analysis of phytoestrogens in soy protein preparations with ultraviolet, electrochemical and thermospray mass spectrometric detection. J Chromatogr 1987;386:315-23
14. Franke AA, Custer LJ, Cerna CM, Narala K. Rapid HPLC analysis of dietary phytoestrogens from legumes and from human urine. Proc Soc Exp Biol Med 1995;208:18-26
15. Nwannenna AI, Lundh TJ, Madej A, Fredriksson G, Bjornhag G. Clinical changes in ovariectomized ewes exposed to phytoestrogens and 17β-estradiol implants. Proc Soc Exp Biol Med 1995;208:92-7
16. Stevenson JC, Gaspard U, Avouac B, et al. Points to consider for the development of new indications for hormone replacement therapies and estrogen-like molecules. Climacteric 1998;1: 12-17
17. Murkies AL, Lombard C, Strauss BJ, Wilcox G, Burger HG, Morton MS. Dietary flour supplementation decreases post-menopausal hot flushes: effect of soy and wheat. Maturitas 1995; 21:189-95
18. Dalais FS, Rice GE, Wahlqvist ML, et al. Effects of dietary phytoestrogens in postmenopausal women. Climacteric 1998;1:124-9
19. Shutt DA, Weston R, Hogan J. Quantitative aspects of phytoestrogen metabolism in sheep fed on subterranean clover. Aust J Agric Res 1998; 21:713-22
20. Setchell KD, Borriello SP, Hulme P, Kirk DN, Axelson M. Nonsteroidal estrogens of dietary origin: possible roles in hormone-dependent disease. Am J Clin Nutr 1984;40:569-78
21. Kelly GE, Joannou GE, Reeder AY, Nelson C, Waring MA. The variable metabolic response to dietary isoflavones in humans. Proc Soc Exp Biol Med 1995;208:40-3
22. Knight DC, Eden JA. A review of the clinical effects of phytoestrogens. Obstet Gynecol 1996; 87:897-904