Transketolase in Trypanosoma brucei

Molecular and Biochemical Parasitology

Volumn 179, Issue 1, 2011, Pages 1-7

  Stoffel, Sabine A ^a   Alibu, Vincent P ^b   Hubert, Jane ^c   Ebikeme, Charles ^d   Portais, Jean Charles ^c   Bringaud, Frédéric ^d   Schweingruber, M Ernst ^e   Barrett, Michael P ^b  

^a Pevion Biotech AG   (Switzerland)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

^c UMR792 INGÉNIERIE DES SYSTÈMES BIOLOGIQUES ET DES PROCÉDÉS   (France)

^d CNRS University Bordeaux Segalen   (France)

^e UNIVERSITY OF BERN   (Switzerland)

Author keywords

Metabolic profiling; Metabolism; Pentose phosphate pathway; Transketolase; Trypanosoma brucei

Indexed keywords

RIBOSE 5 PHOSPHATE; SUGAR PHOSPHATE; TRANSKETOLASE; UNCLASSIFIED DRUG; XYLULOSE 5 PHOSPHATE;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CELLULAR DISTRIBUTION; CYTOSOL; ENZYME ACTIVITY; ENZYME ANALYSIS; ESCHERICHIA COLI; GENE DELETION; GENE EXPRESSION; GENOME; GLYCOSOME; HETEROLOGOUS EXPRESSION; LIFE CYCLE; NONHUMAN; PEROXISOMAL TARGETING SIGNAL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PURIFICATION; TRYPANOSOMA BRUCEI;

TRYPANOSOMA BRUCEI;

EID: 80955179572     PISSN: 01666851     EISSN: 18729428     Source Type: Journal    
DOI: 10.1016/j.molbiopara.2011.04.006     Document Type: Article

References (47)

1. T. Wood Physiological functions of the pentose phosphate pathway Cell Biochem Funct 4 1986 241 247
2. M.P. Barrett The pentose phosphate pathway and parasitic protozoa Parasitol Today 13 1997 11 16 (Pubitemid 27072541)
3. G. Schenk, R. Layfield, J.M. Candy, R.G. Duggleby, and P.F. Nixon Molecular evolutionary analysis of the thiamine-diphosphate-dependent enzyme, transketolase J Mol Evol 44 1997 552 572 (Pubitemid 27227501)
4. L.M. Lois, N. Campos, S.R. Putra, K. Danielsen, M. Rohmer, and A. Boronat Cloning and characterization of a gene from Escherichia coli encoding a transketolase-like enzyme that catalyzes the synthesis of D-1-deoxyxylulose 5-phosphate, a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis Proc Natl Acad Sci U S A 95 1998 2105 2110
5. M.J. Waites, and J.R. Quayle The interrelation transketolase and dihydroxyacetone synthase activities in the methylotrophic yeast Candida boidinii J Gen Microbiol 124 1981 309 316 (Pubitemid 11000977)
6. C.M. Sax, C. Salamon, W.T. Kays, J. Guo, F.X. Yu, R.A. Cuthbertson, and J. Piatigorsky Transketolase is a major protein in the mouse cornea J Biol Chem 271 1996 33568 33574 (Pubitemid 27010173)
7. F. Domain, X.R. Bina, S.B. Levy, and A. Transketolase an enzyme in central metabolism, derepresses the marRAB multiple antibiotic resistance operon of Escherichia coli by interaction with MarR Mol Microbiol 66 2007 383 394 (Pubitemid 47482383)
8. G. Schneider, and Y. Lindqvist Crystallography and mutagenesis of transketolase: mechanistic implications for enzymatic thiamine catalysis Biochim Biophys Acta 1385 1998 387 398 (Pubitemid 28310802)
9. P. Asztalos, C. Parthier, R. Golbik, M. Kleinschmidt, G. Hübner, M.S. Weiss, R. Friedemann, G. Wille, and K. Tittmann Strain and near attack conformers in enzymic thiamin catalysis: X-ray crystallographic snapshots of bacterial transketolase in covalent complex with donor ketoses xylulose 5-phosphate and fructose 6-phosphate, and in noncovalent complex with acceptor aldose ribose 5-phosphate Biochemistry 46 2007 12037 12052 (Pubitemid 350022361)
10. S. Gerhardt, S. Echt, M. Busch, J. Freigang, G. Auerbach, G. Bader, W.F. Martin, A. Bacher, R. Huber, and M. Fischer Structure and properties of an engineered transketolase from maize Plant Physiol 132 2003 1941 1949 (Pubitemid 37024155)
11. N.J. Veitch, D.A. Maugeri, J.J. Cazzulo, Y. Lindqvist, and M.P. Barrett Transketolase from Leishmania mexicana has a dual subcellular localisation Biochem J 382 2004 759 767 (Pubitemid 39243943)
12. A. Schellenberger Sixty years of thiamine diphosphate biochemistry Biochim Biophys Acta 1385 1998 177 186 (Pubitemid 28310787)
13. G. Schenk, R.G. Duggleby, and P.F. Nixon Properties and functions of the thiamin diphosphate dependent enzyme transketolase Int J Biochem Cell Biol 30 1998 1297 1318 (Pubitemid 29002974)
14. G.A. Kochetov, and I.A. Sevostyanova Binding of the coenzyme and formation of the transketolase active center IUBMB Life 57 2005 491 497 (Pubitemid 41112987)
15. R.V. Ospanov, G.A. Kochetov, and B.I. Kurganov Theoretical model of interactions between ligand-binding sites in a dimeric protein and its application for the analysis of thiamine diphosphate binding to yeast transketolase Biophys Chem 124 2006 106 114
16. R.V. Ospanov, G.A. Kochetov, and B.I. Kurganov Influence of donor substrate on kinetic parameters of thiamine diphosphate binding to transketolase Biochemistry 72 2007 84 92 (Pubitemid 46219191)
17. H. Juhnke, B. Krems, P. Kotter, and K.D. Entian Mutants that show increased sensitivity to hydrogen peroxide reveal an important role for the pentose phosphate pathway in protection of yeast against oxidative stress Mol Gen Genet 252 1996 456 464
18. K.H. Slekar, D.J. Kosman, and V.C. Culotta The yeast copper/zinc superoxide dismutase and the pentose phosphate pathway play overlapping roles in oxidative stress protection J Biol Chem 271 1996 28831 28836 (Pubitemid 26382581)
19. L. Sabate, R. Franco, E.I. Canela, J.J. Centelles, and M. Cascante A model of the pentose phosphate pathway in rat liver cells Mol Cell Biochem 142 1995 9 17
20. L.G. Boros, J.L. Brandes, F.I. Yusuf, M. Cascante, R.D. Williams, and W.J. Schirmer Inhibition of the oxidative and nonoxidative pentose phosphate pathways by somatostatin: a possible mechanism of antitumor action Med Hypotheses 50 1998 501 506 (Pubitemid 28307913)
21. B. Comín-Anduix, J. Boren, S. Martinez, C. Moro, J.J. Centelles, R. Trebukhina, N. Petushok, W.N. Lee, L.G. Boros, and M. Cascante The effect of thiamine supplementation on tumour proliferation, A metabolic control analysis study Eur J Biochem 268 2001 4177 4182 (Pubitemid 32862878)
22. F.R. Opperdoes, and P. Borst Localization of nine glycolytic enzymes in a microbody-like organelle in Trypanosoma brucei: the glycosome FEBS Lett 80 1977 360 364 (Pubitemid 8168985)
23. P.A. Michels, F. Bringaud, M. Herman, and V. Hannaert Metabolic functions of glycosomes in trypanosomatids Biochim Biophys Acta 1763 2006 1463 1477 (Pubitemid 44880465)
24. S. Besteiro, M.P. Barrett, L. Rivire, and F. Bringaud Energy generation in insect stages of Trypanosoma brucei: metabolism in flux Trends Parasitol 21 2005 185 191 (Pubitemid 40381257)
25. C.N. Cronin, D.P. Nolan, and H.P. Voorheis The enzymes of the classical pentose phosphate pathway display differential activities in procyclic and bloodstream forms of Trypanosoma brucei FEBS Lett 244 1989 26 30 (Pubitemid 19050480)
26. F. Duffieux, J. Van Roy, P.A. Michels, and F.R. Opperdoes The enzymes of the classical pentose phosphate pathway display differential activities in procyclic and bloodstream forms of Trypanosoma brucei J Biol Chem 275 2000 27559 27565
27. D.A. Maugeri, J.J. Cazzulo, R.J. Burchmore, M.P. Barrett, and P.O. Ogbunude Pentose phosphate metabolism in Leishmania mexicana Mol Biochem Parasitol 130 2003 117 125 (Pubitemid 37289129)
28. D.A. Maugeri, and J.J. Cazzulo The pentose phosphate pathway in Trypanosoma cruzi FEMS Microbiol Lett 234 2004 117 123 (Pubitemid 38515760)
29. M. Igoillo-Esteve, and J.J. Cazzulo The glucose-6-phosphate dehydrogenase from Trypanosoma cruzi: its role in the defense of the parasite against oxidative stress Mol Biochem Parasitol 149 2006 170 181 (Pubitemid 44279091)
30. M. Igoillo-Esteve, D. Maugeri, A.L. Stern, P. Beluardi, and J.J. Cazzulo The pentose phosphate pathway in Trypanosoma cruzi: a potential target for the chemotherapy of Chagas disease An Acad Bras Cienc 79 2007 649 663 (Pubitemid 350248758)
31. C. Colasante, M. Ellis, T. Ruppert, and F. Voncken Comparative proteomics of glycosomes from bloodstream form and procyclic culture form Trypanosoma brucei brucei Proteomics 6 2006 3275 3293 (Pubitemid 43886146)
32. F.R. Opperdoes, and J.P. Szikora In silico prediction of the glycosomal enzymes of Leishmania major and trypanosomes Mol Biochem Parasitol 147 2006 193 206
33. M.P. Cunningham, and Vickerman K Antigenic analysis in the Trypanosoma brucei group, using the agglutination reaction Trans R Soc Trop Med Hyg 56 1962 48 59
34. R. Brun, and M. Schönenberger Cultivation and in vitro cloning or procyclic culture forms of Trypanosoma brucei in a semi-defined medium Acta Trop 36 1979 289 292 (Pubitemid 10181444)
35. H. Hirumi, and K. Hirumi Continuous cultivation of Trypanosoma brucei blood stream forms in a medium containing a low concentration of serum protein without feeder cell layers J. Parasitol 75 1989 985 989 (Pubitemid 20099178)
36. V.P. Alibu, L. Storm, S. Haile, C. Clayton, and D. Horn A doubly inducible system for RNA interference and rapid RNAi plasmid construction in Trypanosoma brucei Mol Biochem Parasitol 139 2005 75 82 (Pubitemid 40029598)
37. H. Irmer, and C. Clayton Degradation of the unstable EP1 mRNA in Trypanosoma brucei involves initial destruction of the 3'-untranslated region Nucl Acids Res 29 2001 4707 4715 (Pubitemid 33095032)
38. V.B. Carruthers, L.H. van der Ploeg, and G.A. Cross DNA-mediated transformation of bloodstream-form Trypanosoma brucei Nucl Acids Res 21 1993 2537 2538 (Pubitemid 23180853)
39. C. Naula, V.P. Alibu, J.M. Brock, N.J. Veitch, R.J. Burchmore, and M.P. Barrett A new erythrose 4-phosphate dehydrogenase coupled assay for transketolase J. Biochem Biophys Met 70 2008 1185 1187
40. J. Sambrook, T. Maniatis, and E. Fritsch Molecular Cloning: A Laboratory Manual Cold Spring Harbor 1989 Laboratory Press Cold Spring Harbor, NY
41. R. Hauser, M. Pypaert, T. Häusler, E.K. Horn, and A. Schneider In vitro import of proteins into mitochondria of Trypanosoma brucei and Leishmania tarentolae J Cell Sci 109 1996 517 523 (Pubitemid 26057132)
42. C. Wittmann, J.O. Krömer, P. Kiefer, T. Binz, and E. Heinzle Impact of the cold shock phenomenon on quantification of intracellular metabolites in bacteria Anal Biochem 327 2004 135 139 (Pubitemid 38367993)
43. C. Ebikeme, J. Hubert, M. Biran, G. Gouspillou, P. Morand, N. Plazolles, F. Guegan, P. Diolez, J.M. Franconi, J.C. Portais, and F. Bringaud Ablation of succinate production from glucose metabolism in the procyclic trypanosomes induces metabolic switches to the Gly3p/DHAP shuttle and to proline metabolism J Biol Chem 285 2010 32312 32324
44. L. Wu, M.R. Mashego, J.C. van Dam, A.M. Proell, J.L. Vinke, C. Ras, W.A. van Winden, W.M. van Gulik, and J.J. Heijnen Quantitative analysis of the microbial metabolome by isotope dilution mass spectrometry using uniformly 13C-labeled cell extracts Anal Biochem 336 2005 164 171 (Pubitemid 40038013)
45. T.N. Siegel, D.R. Hekstra, X. Wang, S. Dewell, and G.A. Cross Genome-wide analysis of mRNA abundance in two life-cycle stages of Trypanosoma brucei and identification of splicing and polyadenylation sites Nucleic Acids Res 38 2010 4946 4957
46. B.C. Jensen, D. Sivam, C.T. Kifer, P.J. Myler, and M. Parsons Widespread variation in transcript abundance within and across developmental stages of Trypanosoma brucei BMC Genomics 10 2009 482
47. N.J. Veitch, P.C. Johnson, U. Trivedi, S. Terry, D. Wildridge, and A. MacLeod Digital gene expression analysis of two life cycle stages of the human-infective parasite, Trypanosoma brucei gambiense reveals differentially expressed clusters of co-regulated genes BMC Genomics 11 2010 124