Ablation of succinate production from glucose metabolism in the procyclic trypanosomes induces metabolic switches to the glycerol 3-phosphate/ dihydroxyacetone phosphate shuttle and to proline metabolism

Journal of Biological Chemistry

Volumn 285, Issue 42, 2010, Pages 32312-32324

  Ebikeme, Charles ^a   Hubert, Jane ^c   Biran, Marc ^a   Gouspillou, Gilles ^a   Morand, Pauline ^a   Plazolles, Nicolas ^b   Guegan, Fabien ^b   Diolez, Philippe ^a   Franconi, Jean Michel ^a   Portais, Jean Charles ^c   Bringaud, Frédé Ric ^a  

^a CNRS University Bordeaux Segalen   (France)

^b University Victor Segalen   (France)

^c UMR792 INGÉNIERIE DES SYSTÈMES BIOLOGIQUES ET DES PROCÉDÉS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; FERMENTATION; GLYCEROL; ION CHROMATOGRAPHY; LIFE CYCLE; MAMMALS; PHYSIOLOGY;

DIHYDROXYACETONE PHOSPHATE; GLUCOSE METABOLISM; GLYCEROL PRODUCTION; GLYCOLYTIC FLUX; METABOLIC ADAPTATION; PROLINE METABOLISM; SUCCINATE PRODUCTION; TRYPANOSOMA BRUCEI;

METABOLISM;

DIHYDROXYACETONE PHOSPHATE; GLUCOSE; GLYCEROL; GLYCEROPHOSPHATE; PROLINE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; SUCCINIC ACID;

AMINO ACID METABOLISM; ARTICLE; CELL LINE; FERMENTATION; GENE EXPRESSION; GLUCOSE METABOLISM; GLYCOLYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ION PAIR CHROMATOGRAPHY; MASS SPECTROMETRY; MITOCHONDRION; MUTANT; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; TRYPANOSOMA BRUCEI;

HEXAPODA; MAMMALIA; TRYPANOSOMA BRUCEI;

EID: 77957775869     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.124917     Document Type: Article

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