The effect of intra-articular autogenous bone marrow injection on healing of an acute posterior cruciate ligament injury in rabbits

Arthroscopy - Journal of Arthroscopic and Related Surgery

Volumn 27, Issue 7, 2011, Pages 965-977

  Kim, Eugene ^a   Jeong, Hwa Jae ^a   Park, Se Jin ^a   Kim, Dong Hoon ^a   Jung, Young Bok ^b   Kim, Sang Jun ^b   Choi, Yun Suk ^a   Lim, Jong Jun ^a   Choi, Kyubo ^a   Sohn, Jin Hee ^a   Chae, Seoung Wan ^a   Shin, Hun Kyu ^a  

^a Sungkyunkwan University School of Medicine   (South Korea)

^b Chung Ang University College of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN FIBER; EPIDERMAL GROWTH FACTOR RECEPTOR; GROWTH FACTOR; TRANSFORMING GROWTH FACTOR BETA1; VASCULOTROPIN;

ACUTE POSTERIOR CRUCIATE LIGAMENT RUPTURE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOGENOUS BONE MARROW TRANSPLANTATION; BLOOD VESSEL; BONE MARROW; BONE MARROW TRANSPLANTATION; CELL PROLIFERATION; CONTROLLED STUDY; FEMUR; FIBROBLAST; FRACTURE HEALING; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; INJECTION; KNEE; KNEE LIGAMENT; KNEE LIGAMENT INJURY; NONHUMAN; POSTERIOR CRUCIATE LIGAMENT RECONSTRUCTION; PROTEIN EXPRESSION; RABBIT; SURGICAL TECHNIQUE; TIBIA; TISSUE REPAIR; TREATMENT OUTCOME; TREATMENT RESPONSE;

ACUTE DISEASE; ANIMALS; BLOOD VESSELS; BONE MARROW TRANSPLANTATION; COLLAGEN; IMMUNOHISTOCHEMISTRY; INJECTIONS, INTRA-ARTICULAR; POSTERIOR CRUCIATE LIGAMENT; RABBITS; RUPTURE; TIME FACTORS; TRANSPLANTATION, AUTOLOGOUS; WOUND HEALING;

EID: 80955179509     PISSN: 07498063     EISSN: 15263231     Source Type: Journal    
DOI: 10.1016/j.arthro.2011.02.011     Document Type: Article

References (33)

1. J.M. Murphy, D.J. Fink, E.B. Hunziker, and F.P. Barry Stem cell therapy in a caprine model of osteoarthritis Arthritis Rheum 48 2003 3464 3474 (Pubitemid 37531912)
2. B. Grigolo, G. Lisignoli, G. Desando, and F.P. Barry Osteoarthritis treated with mesenchymal stem cells on hyaluronan-based scaffold in rabbit Tissue Eng Part C Methods 15 2009 647 658
3. K.A. Hildebrand, S.L. Woo, D.W. Smith, and F.P. Barry The effects of platelet-derived growth factor-BB on healing of the rabbit medial collateral ligament An in vivo study Am J Sports Med 26 1998 549 554 (Pubitemid 28346042)
4. E. Kondo, K. Yasuda, M. Yamanaka, A. Minami, and H. Tohyama Effects of administration of exogenous growth factors on biomechanical properties of the elongation-type anterior cruciate ligament injury with partial laceration Am J Sports Med 33 2005 188 196
5. A. Alm, and B. Stromberg Vascular anatomy of the patellar and cruciate ligaments A microangiographic and histologic investigation in the dog Acta Chir Scand Suppl 445 1974 25 35
6. K.D. Shelbourne, T.J. Davis, and D.V. Patel The natural history of acute, isolated, nonoperatively treated posterior cruciate ligament injuries A prospective study Am J Sports Med 27 1999 276 283 (Pubitemid 29239605)
7. Y.B. Jung, S.K. Tae, Y.S. Lee, H.J. Jung, C.H. Nam, and S.J. Park Active non-operative treatment of acute isolated posterior cruciate ligament injury with cylinder cast immobilization Knee Surg Sports Traumatol Arthrosc 16 2008 729 733
8. Y.B. Jung, H.J. Jung, J.J. Yang, and F.P. Barry Characterization of spontaneous healing of chronic posterior cruciate ligament injury: Analysis of instability and magnetic resonance imaging J Magn Reson Imaging 27 2008 1336 1340
9. P.M. Keller, K.D. Shelbourne, J.R. McCarroll, and A.C. Rettig Nonoperatively treated isolated posterior cruciate ligament injuries Am J Sports Med 21 1993 132 136 (Pubitemid 23026958)
10. S. Iwata, Y. Suda, T. Nagura, and F.P. Barry Clinical disability in posterior cruciate ligament deficient patients does not relate to knee laxity, but relates to dynamic knee function during stair descending Knee Surg Sports Traumatol Arthrosc 15 2007 335 342
11. S. Iwata, Y. Suda, T. Nagura, H. Matsumoto, T. Otani, and Y. Toyama Posterior instability near extension is related to clinical disability in isolated posterior cruciate ligament deficient patients Knee Surg Sports Traumatol Arthrosc 15 2007 343 349
12. E. Eriksson Why are some PCL-ruptures almost symptom free and others have "giving-way" problems? Knee Surg Sports Traumatol Arthrosc 15 2007 319
13. J.S. Torg, T.M. Barton, H. Pavlov, and R. Stine Natural history of the posterior cruciate ligament-deficient knee Clin Orthop Relat Res 1989 208 216 (Pubitemid 19226506)
14. U. Bosch, W.J. Kasperczyk, H.J. Oestern, and H. Tscherne Healing phases in autogenous posterior cruciate ligament replacement. A decision aid for after-care. A biomechanical and histologic study Unfallchirurg 93 1990 187 196 (in German) (Pubitemid 20163750)
15. C. Frank, D. Amiel, and W.H. Akeson Healing of the medial collateral ligament of the knee A morphological and biochemical assessment in rabbits Acta Orthop Scand 54 1983 917 923 (Pubitemid 14210699)
16. C. Frank, D. McDonald, J. Wilson, D. Eyre, and N. Shrive Rabbit medial collateral ligament scar weakness is associated with decreased collagen pyridinoline crosslink density J Orthop Res 13 1995 157 165
17. D. Amiel, C.N. Nagineni, S.H. Choi, and J. Lee Intrinsic properties of ACL and MCL cells and their responses to growth factors Med Sci Sports Exerc 27 1995 844 851
18. M.M. Murray, S.D. Martin, T.L. Martin, and M. Spector Histological changes in the human anterior cruciate ligament after rupture J Bone Joint Surg Am 82 2000 1387 1397
19. R.G. Burwell The function of bone marrow in the incorporation of a bone graft Clin Orthop Relat Res 1985 125 141 (Pubitemid 16138039)
20. J. Connolly, R. Guse, L. Lippiello, and R. Dehne Development of an osteogenic bone-marrow preparation J Bone Joint Surg Am 71 1989 684 691 (Pubitemid 19179655)
21. G. Laws, and M. Walton Fibroblastic healing of grade II ligament injuries Histological and mechanical studies in the sheep J Bone Joint Surg Br 70 1988 390 396
22. J. Lee, F.L. Harwood, W.H. Akeson, and D. Amiel Growth factor expression in healing rabbit medial collateral and anterior cruciate ligaments Iowa Orthop J 18 1998 19 25
23. R. Kuroda, M. Kurosaka, S. Yoshiya, and K. Mizuno Localization of growth factors in the reconstructed anterior cruciate ligament: Immunohistological study in dogs Knee Surg Sports Traumatol Arthrosc 8 2000 120 126
24. H.P. Gerber, T.H. Vu, A.M. Ryan, J. Kowalski, Z. Werb, and N. Ferrara VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation Nat Med 5 1999 623 628 (Pubitemid 29289424)
25. H. Lu, L. Qin, W. Cheung, K. Lee, W. Wong, and K. Leung Low-intensity pulsed ultrasound accelerated bone-tendon junction healing through regulation of vascular endothelial growth factor expression and cartilage formation Ultrasound Med Biol 34 2008 1248 1260 (Pubitemid 352010463)
26. K.D. Shelbourne, R.W. Jennings, and T.N. Vahey Magnetic resonance imaging of posterior cruciate ligament injuries: Assessment of healing Am J Knee Surg 12 1999 209 213
27. H. Dejour, and G. Walch Chronic posterior instabilities Orthopade 16 1987 149 156 (in German)
28. B.K. Lee, G.S. Eom, and Y.C. Kee Posterior laxity after conservative treatment of the acute injured posterior cruciate ligament J Korean Knee Soc 15 2003 97 101
29. M. Agung, M. Ochi, S. Yanada, and F.P. Barry Mobilization of bone marrow-derived mesenchymal stem cells into the injured tissues after intraarticular injection and their contribution to tissue regeneration Knee Surg Sports Traumatol Arthrosc 14 2006 1307 1314 (Pubitemid 44800660)
30. M.T. Cheng, H.W. Yang, T.H. Chen, and O.K. Lee Isolation and characterization of multipotent stem cells from human cruciate ligaments Cell Prolif 42 2009 448 460
31. A. Kanaya, M. Deie, N. Adachi, M. Nishimori, S. Yanada, and M. Ochi Intra-articular injection of mesenchymal stromal cells in partially torn anterior cruciate ligaments in a rat model Arthroscopy 23 2007 610 617 (Pubitemid 46873895)
32. W.G. Rodkey, S.P. Arnoczky, and J.R. Steadman Healing of a surgically created partial detachment of the posterior cruciate ligament using marrow stimulation: An experimental study in dogs J Knee Surg 19 2006 14 18
33. Y. Ma, X. Zhang, J. Wang, and F.P. Barry Effect of bone morphogenetic protein-12 gene transfer on posterior cruciate ligament healing in a rabbit model Am J Sports Med 37 2009 599 609