Intra-articular Injection of Mesenchymal Stromal Cells in Partially Torn Anterior Cruciate Ligaments in a Rat Model

Arthroscopy - Journal of Arthroscopic and Related Surgery

Volumn 23, Issue 6, 2007, Pages 610-617

  Kanaya, Atsushi ^a   Deie, Masataka ^a   Adachi, Nobuo ^a   Nishimori, Makoto ^a   Yanada, Shinobu ^a   Ochi, Mitsuo ^a  

^a HIROSHIMA UNIVERSITY   (Japan)

Author keywords

Anterior cruciate ligament; Green fluorescent protein; Intra articular injection; Ligament healing; Mesenchymal stromal cells

Indexed keywords

GREEN FLUORESCENT PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTERIOR CRUCIATE LIGAMENT INJURY; ARTICLE; BIOMECHANICS; CONTROLLED STUDY; MALE; MESENCHYME CELL; NONHUMAN; RAT; SCORING SYSTEM; SURGICAL TECHNIQUE;

ANIMALS; ANTERIOR CRUCIATE LIGAMENT; BIOMECHANICS; DISEASE MODELS, ANIMAL; INJECTIONS, INTRA-ARTICULAR; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; RATS; RATS, SPRAGUE-DAWLEY; STROMAL CELLS; WOUND HEALING;

EID: 34249868740     PISSN: 07498063     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.arthro.2007.01.013     Document Type: Article

References (23)

1. Noyes F.R., Mooar L.A., Moorman III C.T., and McGinniss G.H. Partial tears of the anterior cruciate ligament. Progression to complete ligament deficiency. J Bone Joint Surg Br 71 (1989) 825-833
2. Fruensgaard S., and Johannsen H.V. Incomplete ruptures of the anterior cruciate ligament. J Bone Joint Surg Br 71 (1989) 526-530
3. Kleiner J.B., Roux R.D., Amiel D., and Woo S.L.-Y. Primary healing of the anterior cruciate ligament. Trans Orthop Res Soc 11 (1986) 131
4. Nagineni C.N., Amiel D., Green M.H., Berchuck M., and Akeson W.H. Characterization of the intrinsic properties of the anterior cruciate and medial collateral ligament cells. J Orthop Res 10 (1992) 465-475
5. Fujimoto E., Sumen Y., Ochi M., and Ikuta Y. Spontaneous healing of acute anterior cruciate ligament (ACL) injuries-Conservative treatment using an extension block soft brace without anterior stabilization. Arch Orthop Trauma Surg 122 (2002) 212-216
6. Van Eijk F., Saris D.B.F., Riesle J., et al. Tissue engineering of ligaments: A comparison of bone marrow stromal cells, anterior cruciate ligament, and skin fibroblast as cell source. Tissue Eng 10 (2004) 893-903
7. Chen J., Altman G.H., Karageorgiou V., et al. Human bone marrow stromal cell and ligament fibroblast responses on RGD-modified silk fibers. J Biomed Mater Res A 67 (2003) 559-570
8. Murphy J.M., Fink D.J., Hunziker E.B., and Barry F.P. Stem cell therapy in a caprine model of osteoarthritis. Arthritis Rheum 48 (2003) 3464-3474
9. Agung M., Ochi M., Yanada S., et al. Mobilization of bone marrow-derived mesenchymal stem cells into the injured tissues after intraarticular injection and their contribution to tissue regeneration. Knee Surg Sports Traumatol Arthrosc 14 (2006) 1307-1314
10. Rodeo S.A., Seneviratne A., Suzuki K., Felker K., Wickiewicz T.L., and Warren R.F. Histological analysis of human meniscal allografts. A preliminary report. J Bone Joint Surg Am 82 (2000) 1071-1082
11. Deie M., Ochi M., and Ikuta Y. High intrinsic healing potential of human anterior cruciate ligament. Acta Orthop Scand 66 (1995) 28-32
12. Frank C., Schachar N., and Dittrich D. Natural history of healing in the repaired medial collateral ligament. J Orthop Res 1 (1983) 179-188
13. Frank C., Amiel D., Woo S.L.-Y., and Akeson W. Normal ligament properties and ligament healing. Clin Orthop Relat Res (1985) 15-25
14. Bray R.C., Leonard C.A., and Salo P.T. Vascular physiology and long-term healing of partial ligament tears. J Orthop Res 20 (2002) 984-989
15. Weissman I.L. Translating stem and progenitor cell biology to the clinic: Barriers and opportunities. Science 287 (2000) 1442-1446
16. Lee J., Harwood F.L., Akeson W.H., and Amiel D. Growth factor expression in healing rabbit medial collateral and anterior cruciate ligaments. Iowa Orthop J 18 (1998) 19-25
17. Kuroda R., Kurosaka M., Yoshiya S., and Mizuno K. Localization of growth factors in the reconstructed anterior cruciate ligament: Immunohistological study in dogs. Knee Surg Sports Traumatol Arthrosc 8 (2000) 120-126
18. Murray M.M., Spindler K.P., Devin C., et al. Use of a collagen-platelet rich plasma scaffold to stimulate healing of a central defect in the canine ACL. J Orthop Res 24 (2006) 820-830
19. Huibregtse B.A., Jhonstone B., Goldberg V.M., and Caplan A.I. Effect of age and sampling site on the chondro-osteogenic potential of rabbit marrow-derived mesenchymal progenitor cells. J Orthop Res 18 (2000) 18-24
20. Kotobuki N., Hirose M., Takakura Y., and Ohgushi H. Cultured autologous human cells for hard tissue regeneration: Preparation and characterization of mesenchymal stem cells from bone marrow. Artif Organs 28 (2004) 33-39
21. Hefti F.L., Kress A., Fasel J., and Morscher E.W. Healing of the transected anterior cruciate ligament in the rabbit. J Bone Joint Surg Am 73 (1991) 373-383
22. O'Donoghue D.H., Rockwood Jr. C.A., Frank G.R., Jack S.C., and Kenyon R. Repair of the anterior cruciate ligament in dogs. J Bone Joint Surg Am 48 (1996) 503-519
23. Wiig M.E., Amiel D., VandeBerg J., Kitabayashi L., Harwood F.L., and Arfors K.E. The early effect of high molecular weight hyaluronan (hyaluronic acid) on anterior cruciate ligament healing: An experimental study in rabbits. J Orthop Res 8 (1990) 425-434