Novel crystallization conditions for tandem variant R67 DHFR yield a wild-type crystal structure

Acta Crystallographica Section F: Structural Biology and Crystallization Communications

Volumn 67, Issue 11, 2011, Pages 1316-1322

  Yachnin, Brahm J ^a,b,c   Colin, Damien Y ^c,d   Volpato, Jordan P ^c,d   Ebert, Maximilian ^c,d   Pelletier, Joelle N ^c,d   Berghuis, Albert M ^a,b,c  

^a MCGILL UNIVERSITY   (Canada)

^b Groupe de Recherche GRASP   (Canada)

^c Groupe de Recherche PROTEO   (Canada)

^d UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

antibiotic resistance; dihydrofolate reductase; in situ proteolysis; protein degradation; type II DHFR

Indexed keywords

DIHYDROFOLATE REDUCTASE;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; CRYSTALLIZATION; GENETICS; MUTATION; PROMOTER REGION; PROTEIN QUATERNARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; MODELS, MOLECULAR; MUTATION; PROMOTER REGIONS, GENETIC; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; TETRAHYDROFOLATE DEHYDROGENASE;

BACTERIA (MICROORGANISMS);

EID: 80955155595     PISSN: None     EISSN: 17443091     Source Type: Journal    
DOI: 10.1107/S1744309111030417     Document Type: Article

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