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Volumn 7, Issue 1, 2011, Pages 495-499

Minimally invasive biomarker confirms glial activation present in Alzheimer's disease: A preliminary study

Author keywords

Alzheimer's disease; Glial activation; Noninvasive biomarker

Indexed keywords

ACETIC ACID C 13; BICARBONATE; GLUTAMIC ACID; GLUTAMINE; STABLE ISOTOPE; UNCLASSIFIED DRUG;

EID: 80955132633     PISSN: 11766328     EISSN: 11782021     Source Type: Journal    
DOI: 10.2147/ndt.s23721     Document Type: Article
Times cited : (25)

References (33)
  • 1
    • 78751635081 scopus 로고    scopus 로고
    • Genome-wide association study of CSF biomarkers Abeta1-42, t-tau, and p-tau181p in the ADNI cohort
    • Kim S, Swaminathan S, Shen L, et al. Genome-wide association study of CSF biomarkers Abeta1-42, t-tau, and p-tau181p in the ADNI cohort. Neurology. 2011;76(1):69-79.
    • (2011) Neurology , vol.76 , Issue.1 , pp. 69-79
    • Kim, S.1    Swaminathan, S.2    Shen, L.3
  • 2
    • 79958102380 scopus 로고    scopus 로고
    • Qualification of the analytical and clinical performance of CSF biomarker analyses in ADNI
    • Shaw LM, Vanderstichele H, Knapik-Czajka M, et al. Qualification of the analytical and clinical performance of CSF biomarker analyses in ADNI. Acta Neuropathol. 2011;121(5):597-609.
    • (2011) Acta Neuropathol , vol.121 , Issue.5 , pp. 597-609
    • Shaw, L.M.1    Vanderstichele, H.2    Knapik-Czajka, M.3
  • 3
    • 77955973836 scopus 로고    scopus 로고
    • Neuroinflammation, microglia and implications for anti-inflammatory treatment in Alzheimer's disease
    • Krause DL, Muller N. Neuroinflammation, microglia and implications for anti-inflammatory treatment in Alzheimer's disease. Int J Alzheimers Dis. 2010;2010:732806.
    • (2010) Int J Alzheimers Dis , vol.2010 , pp. 732806
    • Krause, D.L.1    Muller, N.2
  • 4
    • 72049130805 scopus 로고    scopus 로고
    • Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade
    • Jack CR Jr, Knopman DS, Jagust WJ, et al. Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade. Lancet Neurol. 2010;9(1):119-128.
    • (2010) Lancet Neurol , vol.9 , Issue.1 , pp. 119-128
    • Jack Jr., C.R.1    Knopman, D.S.2    Jagust, W.J.3
  • 5
    • 33645894186 scopus 로고    scopus 로고
    • MRS shows abnormalities before symptoms in familial Alzheimer disease
    • Godbolt AK, Waldman AD, MacManus DG, et al. MRS shows abnormalities before symptoms in familial Alzheimer disease. Neurology.2006;66(5):718-722.
    • (2006) Neurology , vol.66 , Issue.5 , pp. 718-722
    • Godbolt, A.K.1    Waldman, A.D.2    Macmanus, D.G.3
  • 6
    • 0031283198 scopus 로고    scopus 로고
    • In vivo magnetic resonance spectroscopy of human brain: The biophysical basis of dementia
    • Ross BD, Bluml S, Cowan R, Danielsen E, Farrow N, Gruetter R. In vivo magnetic resonance spectroscopy of human brain: the biophysical basis of dementia. Biophys Chem. 1997;68(1-3):161-172.
    • (1997) Biophys Chem , vol.68 , Issue.1-3 , pp. 161-172
    • Ross, B.D.1    Bluml, S.2    Cowan, R.3    Danielsen, E.4    Farrow, N.5    Gruetter, R.6
  • 7
    • 0009743529 scopus 로고    scopus 로고
    • Proton magnetic resonance spectroscopy: The new gold standard for diagnosis of clinical and subclinical hepatic encephalopathy?
    • Ross BD, Danielsen ER, Bluml S. Proton magnetic resonance spectroscopy: the new gold standard for diagnosis of clinical and subclinical hepatic encephalopathy? Dig Dis. 1996;14(Suppl 1):30-39.
    • (1996) Dig Dis , vol.14 , Issue.SUPPL. 1 , pp. 30-39
    • Ross, B.D.1    Danielsen, E.R.2    Bluml, S.3
  • 10
    • 0036522961 scopus 로고    scopus 로고
    • Astroglial contribution to brain energy metabolism in humans revealed by 13C nuclear magnetic resonance spectroscopy: Elucidation of the dominant pathway for neurotransmitter glutamate repletion and measurement of astrocytic oxidative metabolism
    • Lebon V, Petersen KF, Cline GW, et al. Astroglial contribution to brain energy metabolism in humans revealed by 13C nuclear magnetic resonance spectroscopy: elucidation of the dominant pathway for neurotransmitter glutamate repletion and measurement of astrocytic oxidative metabolism. J Neurosci. 2002;22(5):1523-1531.
    • (2002) J Neurosci , vol.22 , Issue.5 , pp. 1523-1531
    • Lebon, V.1    Petersen, K.F.2    Cline, G.W.3
  • 11
    • 0038650885 scopus 로고    scopus 로고
    • In vivo NMR studies of the glutamate neurotransmitter flux and neuroenergetics: Implications for brain function
    • Rothman DL, Behar KL, Hyder F, Shulman RG. In vivo NMR studies of the glutamate neurotransmitter flux and neuroenergetics: implications for brain function. Annu Rev Physiol. 2003;65:401-427.
    • (2003) Annu Rev Physiol , vol.65 , pp. 401-427
    • Rothman, D.L.1    Behar, K.L.2    Hyder, F.3    Shulman, R.G.4
  • 12
    • 0035065635 scopus 로고    scopus 로고
    • 1-(13)C glucose magnetic resonance spectroscopy of pediatric and adult brain disorders
    • Bluml S, Moreno A, Hwang JH, Ross BD. 1-(13)C glucose magnetic resonance spectroscopy of pediatric and adult brain disorders. NMR Biomed. 2001;14(1):19-32.
    • (2001) NMR Biomed , vol.14 , Issue.1 , pp. 19-32
    • Bluml, S.1    Moreno, A.2    Hwang, J.H.3    Ross, B.D.4
  • 15
    • 0014526611 scopus 로고
    • Compartmentation of glutamate metabolism in brain. Evidence for the existence of two different tricarboxylic acid cycles in brain
    • Van den Berg CJ, Krzalic L, Mela P, Waelsch H. Compartmentation of glutamate metabolism in brain. Evidence for the existence of two different tricarboxylic acid cycles in brain. Biochem J. 1969;113(2): 281-290.
    • (1969) Biochem J , vol.113 , Issue.2 , pp. 281-290
    • van den Berg, C.J.1    Krzalic, L.2    Mela, P.3    Waelsch, H.4
  • 17
    • 0022505025 scopus 로고
    • Acetate and fluoroacetate as possible markers for glial metabolism in vivo
    • Muir D, Berl S, Clarke DD. Acetate and fluoroacetate as possible markers for glial metabolism in vivo. Brain Res. 1986;380(2):336-340.
    • (1986) Brain Res , vol.380 , Issue.2 , pp. 336-340
    • Muir, D.1    Berl, S.2    Clarke, D.D.3
  • 18
    • 73949084714 scopus 로고    scopus 로고
    • Altered brain mitochondrial metabolism in healthy aging as assessed by in vivo magnetic resonance spectroscopy
    • Boumezbeur F, Mason GF, de Graaf RA, et al. Altered brain mitochondrial metabolism in healthy aging as assessed by in vivo magnetic resonance spectroscopy. J Cereb Blood Flow Metab. 2010;30(1):211-221.
    • (2010) J Cereb Blood Flow Metab , vol.30 , Issue.1 , pp. 211-221
    • Boumezbeur, F.1    Mason, G.F.2    de Graaf, R.A.3
  • 19
    • 78649447459 scopus 로고    scopus 로고
    • Swift Acetate Glial Assay (SAGA): An accelerated human (1)(3)C MRS brain exam for clinical diagnostic use
    • Sailasuta N, Tran TT, Harris KC, Ross BD. Swift Acetate Glial Assay (SAGA): an accelerated human (1)(3)C MRS brain exam for clinical diagnostic use. J Magn Reson. 2010;207(2):352-355.
    • (2010) J Magn Reson , vol.207 , Issue.2 , pp. 352-355
    • Sailasuta, N.1    Tran, T.T.2    Harris, K.C.3    Ross, B.D.4
  • 21
    • 4544335597 scopus 로고    scopus 로고
    • Mild cognitive impairment as a diagnostic entity
    • Petersen RC. Mild cognitive impairment as a diagnostic entity. J Intern Med. 2004;256(3):183-194.
    • (2004) J Intern Med , vol.256 , Issue.3 , pp. 183-194
    • Petersen, R.C.1
  • 23
    • 77953510479 scopus 로고    scopus 로고
    • Metabolic abnormalities in abstinent methamphetamine dependent subjects
    • Sailasuta N, Abulseoud O, Hernandez M, Haghani P, Ross BD. Metabolic abnormalities in abstinent methamphetamine dependent subjects. Subst Abuse. 2010;2010(4):9-20.
    • (2010) Subst Abuse , vol.2010 , Issue.4 , pp. 9-20
    • Sailasuta, N.1    Abulseoud, O.2    Hernandez, M.3    Haghani, P.4    Ross, B.D.5
  • 24
    • 0027375098 scopus 로고
    • Estimation of metabolite concentrations from localized in vivo proton NMR spectra
    • Provencher SW. Estimation of metabolite concentrations from localized in vivo proton NMR spectra. Magn Reson Med. 1993;30(6): 672-679.
    • (1993) Magn Reson Med , vol.30 , Issue.6 , pp. 672-679
    • Provencher, S.W.1
  • 25
    • 39149143342 scopus 로고    scopus 로고
    • Immune activation of the central nervous system is still present after.4 years of effective highly active antiretroviral therapy
    • Eden A, Price RW, Spudich S, Fuchs D, Hagberg L, Gisslen M. Immune activation of the central nervous system is still present after.4 years of effective highly active antiretroviral therapy. J Infect Dis. 2007;196(12):1779-1783.
    • (2007) J Infect Dis , vol.196 , Issue.12 , pp. 1779-1783
    • Eden, A.1    Price, R.W.2    Spudich, S.3    Fuchs, D.4    Hagberg, L.5    Gisslen, M.6
  • 26
    • 0034881619 scopus 로고    scopus 로고
    • Basal ganglia metabolite abnormalities in minor motor disorders associated with human immunodeficiency virus type 1
    • Von Giesen HJ, Wittsack HJ, Wenserski F, Koller H, Hefter H, Arendt G. Basal ganglia metabolite abnormalities in minor motor disorders associated with human immunodeficiency virus type 1. Arch Neurol. 2001;58(8):1281-1286.
    • (2001) Arch Neurol , vol.58 , Issue.8 , pp. 1281-1286
    • von Giesen, H.J.1    Wittsack, H.J.2    Wenserski, F.3    Koller, H.4    Hefter, H.5    Arendt, G.6
  • 27
    • 45949092844 scopus 로고    scopus 로고
    • Methamphetamine causes microglial activation in the brains of human abusers
    • Sekine Y, Ouchi Y, Sugihara G, et al. Methamphetamine causes microglial activation in the brains of human abusers. J Neurosci. 2008;28(22): 5756-5761.
    • (2008) J Neurosci , vol.28 , Issue.22 , pp. 5756-5761
    • Sekine, Y.1    Ouchi, Y.2    Sugihara, G.3
  • 28
    • 70349782434 scopus 로고    scopus 로고
    • The role of glial cells in drug abuse
    • Miguel-Hidalgo JJ. The role of glial cells in drug abuse. Curr Drug Abuse Rev. 2009;2(1):72-82.
    • (2009) Curr Drug Abuse Rev , vol.2 , Issue.1 , pp. 72-82
    • Miguel-Hidalgo, J.J.1
  • 29
    • 54949085009 scopus 로고    scopus 로고
    • Roscovitine reduces neuronal loss, glial activation, and neurologic deficits after brain trauma
    • Hilton GD, Stoica BA, Byrnes KR, Faden AI. Roscovitine reduces neuronal loss, glial activation, and neurologic deficits after brain trauma. J Cereb Blood Flow Metab. 2008;28(11):1845-1859.
    • (2008) J Cereb Blood Flow Metab , vol.28 , Issue.11 , pp. 1845-1859
    • Hilton, G.D.1    Stoica, B.A.2    Byrnes, K.R.3    Faden, A.I.4
  • 30
    • 77349114038 scopus 로고    scopus 로고
    • Progressive changes in microglia and macrophages in spinal cord and peripheral nerve in the transgenic rat model of amyotrophic lateral sclerosis
    • Graber DJ, Hickey WF, Harris BT. Progressive changes in microglia and macrophages in spinal cord and peripheral nerve in the transgenic rat model of amyotrophic lateral sclerosis. J Neuroinflammation.2010;7:8.
    • (2010) J Neuroinflammation , vol.7 , pp. 8
    • Graber, D.J.1    Hickey, W.F.2    Harris, B.T.3
  • 31
    • 0036850023 scopus 로고    scopus 로고
    • Neuroinflammation in Alzheimer's disease and prion disease
    • Eikelenboom P, Bate C, Van Gool WA, et al. Neuroinflammation in Alzheimer's disease and prion disease. Glia. 2002;40(2):232-239.
    • (2002) Glia , vol.40 , Issue.2 , pp. 232-239
    • Eikelenboom, P.1    Bate, C.2    van Gool, W.A.3
  • 33
    • 1542284679 scopus 로고    scopus 로고
    • Reduced glutamate neurotransmission in patients with Alzheimer's disease - an in vivo (13)C magnetic resonance spectroscopy study
    • Lin AP, Shic F, Enriquez C, Ross BD. Reduced glutamate neurotransmission in patients with Alzheimer's disease - an in vivo (13)C magnetic resonance spectroscopy study. MAGMA. 2003;16(1):29-42.
    • (2003) MAGMA , vol.16 , Issue.1 , pp. 29-42
    • Lin, A.P.1    Shic, F.2    Enriquez, C.3    Ross, B.D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.