In viva magnetic resonance spectroscopy of human brain: The biophysical basis of dementia

Biophysical Chemistry

Volumn 68, Issue 1-3, 1997, Pages 161-172

  Ross, Brian D ^a   Bluml, Stefan ^a   Cowan, Robert ^a   Danielsen, Else ^a   Farrow, Neil ^a   Gruetter, Rolf ^a  

^a HUNTINGTON MEDICAL RESEARCH INSTITUTES   (United States)

Author keywords

Alzheimer disease; Neurochemistry disorders; Neuronal markers; Neurotransmitters; Nuclear magnetic resonance spectroscopy

Indexed keywords

ALZHEIMER DISEASE; BIRTH INJURY; BRAIN DISEASE; CONFERENCE PAPER; DEMENTIA; DIAGNOSTIC IMAGING; GLYCOLYSIS; HUMAN; HUMAN TISSUE; IN VIVO STUDY; MONITORING; NEUROTRANSMITTER RELEASE; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; ANIMAL; BIOPHYSICS; BRAIN; METABOLISM; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE; REVIEW;

ANIMALS; BIOPHYSICS; BRAIN; DEMENTIA; HUMANS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR;

EID: 0031283198     PISSN: 03014622     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0301-4622(97)00032-X     Document Type: Conference Paper

References (65)

1. K.R. Thulborn, G.H. du Boulay, O.K. Radda, Proc. of the Xth Int. Symp. on Cerebral Blood Flow and Metab., 1981.
2. E.B. Cady, M.J. Dawson, P.L. Hope et al., Non-invasive investigation of cerebral metabolism in newborn infants by phosphorus nuclear magnetic resonance spectroscopy, Lancet 1 (1983) 1059-1062.
3. P.L. Hope, E.B. Cady, P.S. Tofts et al., Cerebral energy metabolism studied with phosphorus NMR spectroscopy in normal and birth-asphyxiated infants, Lancet 1 (1984) 366-370.
4. P.A. Hamilton, P.L. Hope, E.B. Cady, D.T. Delpy, J.S. Wyatt, E.O.R. Reynolds, Impaired energy metabolism in brains of newborn infants with increased cerebral echodensities, Lancet 2 (1986) 1242-1246.
5. P.A. Bottomley, H.R. Hart, W.A. Edelstein et al., NMR imaging/spectroscopy system to study both anatomy and metabolism, Lancet 1 (1983) 273-274.
6. R.D. Oberhaensli, D. Hilton Jones, P.J. Bore, L.J. Hands, R.P. Rampling, G.K. Radda, Biochemical investigation of human tumours in vivo with phosphorus-31 magnetic resonance spectroscopy, Lancet 2 (1986) 8-11.
7. K.M.A. Welch, Proc. 11th Soc. of Magn. Resonance in Medicine, Berlin, 1 (1992) 901.
8. J.W. Pettegrew, N.J. Minstew, MM. Cohen, S.J. Kopp, T. Glonek, P-31 NMR changes in Alzheimer and Huntington diseased brain, Neurology 34 (1984) 281.
9. H.H. Tallan, Studies on the distribution of N-acetyl-L-aspartic acid in brain, J. Biol. Chem. 224 (1957) 41-45.
10. 1H NMR study of cerebral hypoxia in vivo, Proc. Natl. Acad. Sci. USA 80 (1983) 4945-4948.
11. B. Ross, T. Michaelis, Clinical applications of magnetic resonance spectroscopy, Magn. Reson. Quart. 10 (1994) 191-247.
12. J. Frahm, H. Bruhn, M.L. Gyngcll, K.-D. Merboldt, W. Hänicke, R. Sauter, Localized proton NMR spectroscopy in different regions of the human brain in vivo. Relaxation times and concentrations of cerebral metabolites, Magn. Reson. Med. 11 (1989) 47-63.
13. J. Frahm, T. Michaelis, K.-D. Merboldt. H. Bruhn, M.L. Gyngell, W. Hänicke, Improvements in localized proton NMR spectroscopy of human brain. Water suppression, short echo times, and 1 ml resolution, J. Magn. Reson. 90 (1990) 464-473.
14. J. Frahm, T. Michaelis, K.-D. Merboldt et al., Localized NMR spectroscopy in vivo: progress and problems, NMR Biomed. 2 (5/6) (1988) 188-195.
15. 1H NMR spectra of metabolites in the human brain, Proc. Natl. Acad. sci. USA 85 (1988) 1821-1825.
16. R. Kreis, N.A. Farrow, B.D. Ross, Diagnosis of hepatic encephalopathy by proton magnetic resonance spectroscopy, Lancet 336 (1990) 635-636.
17. 1H NMR spectra of human brain in vivo, NMR Biomed. 4(1991) 90-98.
18. 31P NMR, Proc. Natl. Acad. Sci. USA 80 (1983) 2748-2751.
19. B.D. Ross, R. Kreis, T. Ernst, Clinical tools for the 90's: Magnetic resonance spectroscopy and metabolite imaging, Eur. J. Radiol. 14 (1992) 128-140.
20. B.L. Miller, R. Moats, T. Shonk, T. Ernst, S. Woolley, B.D. Ross, Alzheimer disease: Depiction of increased cerebral myo-inositol with proton MR spectroscopy, Radiology 187 (1993) 433-437.
21. 1H MRS permits new diagnostic accuracy in patients with Alzheimer disease, TAMU Newslett. 413 (1993) 13-14.
22. R.A. Moats, T. Ernst, T.K. Shonk, B.D. Ross, Abnormal cerebral metabolite concentrations in patients with probable Alzheimer disease, Magn. Reson. Med. 32 (1994) 110-115.
23. T.K. Shonk, R.A. Moats, P. Gifford et al., Probable Alzheimer disease: Diagnosis with Proton MR Spectroscopy, Radiology 195 (1995) 65-72.
24. T. Michaelis, J. Videen, M.S. Linsey, B.D. Ross, Proc. 2nd Society of Magn. Resonance, San Francisco, 1 (1994) 306.
25. R. Kreis, B.D. Ross, Cerebral metabolic disturbances in patients with sub-acute and chronic diabetes mellitus by proton magnetic resonance spectroscopy, Radiology 184 (1992) 123-130.
26. J.H. Lee, E. Arcinue, B.D. Ross, Organic osmolytes in the brain of an infant with hypernatremia, New Eng. J. Med. 331 (7) (1994) 439-442.
27. 1H NMR spectroscopy in patients with chronic hepatic encephalopathy. Analysis of changes in cerebral glutamine, choline and inositols, NMR Biomed. 4 (1991) 109-116.
28. 1H MRS, Radiology 182 (1992) 19-27.
29. B.D. Ross, S. Jacobson, F. Villamil et al., Subclinical hepatic encephalopathy: Proton MR spectroscopic abnormalities, Radiology 193 (1994) 457-463.
30. J.S. Videen, T. Michaelis, P. Pinto, B.D. Ross, Human cerebral osmolytes during chronic hyponatremia: A proton magnetic resonance spectroscopy study, J. Clin. Invest. 95 (1995) 788-793.
31. R.A. Moats, T. Shonk, Evaluation of an automated MRS examination: Application in Alzheimer disease, Am. J. Neuroradiol. 16(1995) 1779-1782.
32. R.A. Moats, L. Watson, T. Shonk et al., Added value of automated clinical MRS of the brain, J. Comput. Assist. Tomogr. 19 (3) (1995) 480-491.
33. D.J. Selkoe, Alzheimer's disease: A central role for amyloid, J. Neuropath. Exptl. Neurol. 53 (1994) 438-447.
34. J.N. Kanfer, J.W. Pettegrew, J. Moossy, D.G.D.O. McCartney, Alterations of selected enzymes of phospholipid metabolism in Alzheimer's disease brain tissue as compared to non-Al-zheimer's demented controls, Biochem. Res. 18 (3) (1993) 331-334.
35. W.J. Strittmatter, A.M. Saunders, D. Schmechel et al., Apolipoprotein E: High-avidity binding to β-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease, Proc. Natl. Acad. Sci. USA 90 (1993) 1977-1981.
36. A.M. Saunders, W.J. Strittmatter, D. Schmechel, Association of apolipoprotein E allele e4 with late onset familial and sporadic Alzheimer's disease, Neurology 43 (1994) 1467-1472.
37. B.T. Hyman, R.D. Terry, Apolipoprotein E, amyloid and Alzheimer's disease: An editorial, J. Neuropath. Exptl. Neurology 53 (1994) 427-428.
38. N. Maltby, G.A. Broe, H. Creasey, A.F. Jorm, H. Christensen, W.S. Brooks, Efficacy of tacrine and lecithin in mild to moderate Alzheimer's disease: double blind trial, Brit. Med. J. 308(1994) 879-883.
39. M.P. Honchar, G.P. Vogler, B.G. Gish, W.R. Sherman, Evidence that phosphoinositide metabolism in rat cerebral cortex stimulated by pilocarpine, physostigmine and pargyline in vivo is not changed by chronic lithium treatment, Neurochem. 55 (1990) 1521-1525.
40. E.D. Kennedy, J.R.A. Challiss, C.L. Ragan, S.F. Nahorski, Reduced inositol polyphosphate accumulation and inositol supply induced by lithium in stimulated cerebral cortex slices, Biochem. J. 267 (1990) 781-786.
41. C.E. Stokes, J.N. Hawthorne, Reduced phosphoinositide concentrations in anterior temporal cortex of Alzheimer-Diseased brains, J. Neurochem. 48 (1987) 1018-1021.
42. J. Jolles, J. Bothmer, M Markerink, R. Ravid, Phosphatidylinositol kinase is reduced in Alzheimer's disease, J. Neurochem. 58 (1992) 2326-2329.
43. R.A. Moats, T. Shonk, T. Ernst, B.L. Miller, B.D. Ross, Proc. 12th Soc. of Magn. Resonance in Med., New York, 1 (1993) 230.
44. T. Shonk, B.D. Ross, Role of increased cerebral myo-inositol in the dementia of Down syndrome, Magn. Reson. Med. 33 (1995) 858-861.
45. T. Dyrks, A. Weidemann, G. Multhaup et al., Identification, transmembrane orientation and biogenesis of the amyloid A4 precursor of Alzheimer disease, EMBO J. 7 (1988) 949-957.
46. T. Henriksson, R.M. Barbour, S. Braa et al., Analysis and quantification of the β-amyloid precursor protein in the cerebrospinal fluid of Alzheimer's disease patients with a monoclonal antibody-based immunoassay, J. Neurochem. 56 (1991) 1037-1042.
47. B.A. Yankner, M.-M. Mesulam, β-Amyloid and the pathogenesis of Alzheimer's disease, New Engl. J. Med. 325 (326) (1991) 1849-1857.
48. K. Beyreuther, T. Dyrks, C. Hilbich, et al., in: Down Syndrome and Alzheimer Disease. Wiley-Liss, Sussex, 1992, pp. 159-182.
49. R.S. Badar-Goffer, O. Ben-Yoseph, H.S. Bachelard, P.G. Morris, Neuronal-glial metabolism under depolarizing conditions, Biochem. J. 282 (1992) 225-230.
50. B.R. Fruen, B.R. Lester, Downs syndrome fibroblasts exhibit enhanced ml uptake, Biochem. J. 270 (1990) 119-123.
51. B.R. Fruen, B.R. Lester, Inositol and inositol 1,4,5-triphosphate content of Down syndrome fibroblasts exhibiting enhanced inositol uptake, Fed. Eur. Biochem. Soc. 295 (1991) 43-47.
52. J.H. Allison, R.L. Boshans, L.M. Hallcher, P.M. Packman, W.R. Sherman, The effects of lithium on myo-inositol levels in layers of frontal cerebral cortex, in cerebellum, and in corpus callosum of the rat, J. Neurochem. 34 (2) (1980) 456-458.
53. M.J. Berridge, C.P. Downes, M.R. Hanley, Neural and developmental actions of lithium: A unifying hypothesis, Cell 59 (1989) 411-419.
54. M.R. Hirvonen, K. Savolainen, Lithium-induced decrease of brain inositol and increase of brain inosilol-1-phosphate is transient, Neurochem. Res. 16 (1991) 905-911.
55. M.D. Tricklebank, L. Singh, A. Jackson, R.J. Oles, Evidence that a proconvulsant action of lithium is mediated by inhibition of myo-inositol phosphatase in mouse brain, Brain Res. 558 (1991) 145-148.
56. N.E. Preece, D.G. Gadian, J. Houseman, S.R. Williams, Lithium-induced modulation of cerebral inositol phosphate metabolism in the rat: a multinuclear magnetic resonance study in vivo, Lithium 3 (1992) 287-297.
57. S.J. Pollack, J.R. Atack, M.R. Knowles et al., Mechanism of inositol monophosphatase, the putative target of lithium therapy, Proc. Natl. Acad. Sci. USA 91 (1994) 5766-5770.
58. J.M. Baraban, Commentary: Toward a crystal-clear view of lithium's site of action, Proc. Natl. Acad. Sci. USA 91 (1994) 5738-5739.
59. R. Kreis, T. Ernst, B.D. Ross, Absolute quantitation of water and metabolites in the human brain. Part II: Metabolite concentrations, J. Magn. Reson. 102 (1) (1993) 9-19.
60. R. Gruetter, E.R. Danielsen, B.D. Ross, Proc. Eur. Soc. of Magn. Resonance in Med. and Biol., Prague, 1996.
61. S. Bluml, L.J. Haseler, E.R. Danielsen, B.D. Ross, Proc. 4th Soc. of Magn. Resonance, New York, 1 (1996) 467.
62. E.R. Danielsen, S. Bluml, B.D. Ross, Proc. 4th Soc. of Magn. Resonance, New York, 2 (1996) 1231.
63. S. Bluml, E.R. Danielsen, Proc. Eur. Soc. for Magn. Resonance in Med. and Biol., Prague, 1996.
64. S. Bluml, E.R. Danielsen, B.D. Ross, Proc. 4th Int. Soc. of Magnetic Resonance in Medicine, New York, 1 (1996) 304.
65. K. Kanamori, B.D. Ross, J.C. Chung, E.L. Kuo, Severity of hyperammonemic encephalopathy correlates with brain ammonia level and saturation of glutamine synthetase in vivo, J. Neurochem. 67 (1996) 1584-1594.