Glial dysfunction in abstinent methamphetamine abusers

Journal of Cerebral Blood Flow and Metabolism

Volumn 30, Issue 5, 2010, Pages 950-960

  Sailasuta, Napapon ^a   Abulseoud, Osama ^b   Harris, Kent C ^a   Ross, Brian D ^a,c  

^a HUNTINGTON MEDICAL RESEARCH INSTITUTES   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c Rudi Schulte Research Institute   (United States)

Author keywords

Acetate; Glutamate; MR spectroscopy; Neurochemistry; Neuronal?glial interaction; Neurotransmitters

Indexed keywords

BICARBONATE; GLUTAMIC ACID; METHAMPHETAMINE;

ADULT; ARTICLE; BRAIN METABOLISM; CARBON NUCLEAR MAGNETIC RESONANCE; CELL DAMAGE; CITRIC ACID CYCLE; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG ABUSE; FEMALE; FRONTAL CORTEX; GLIAL DYSFUNCTION; GRAY MATTER; HUMAN; PRIORITY JOURNAL;

ACETATES; ADULT; AMPHETAMINE-RELATED DISORDERS; BICARBONATES; BRAIN; CARBON ISOTOPES; DRUG USERS; FEMALE; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MALE; METHAMPHETAMINE; NEUROGLIA; OXIDATION-REDUCTION; PILOT PROJECTS;

EID: 77952010140     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1038/jcbfm.2009.261     Document Type: Article

References (46)

1. Abulseoud O, Sailasuta N, Hernandez M, Ross BD (2009) Impact of depression on cerebral and cognitive function in abstinent methamphetamine users. Proc Int Soc Magn Reson Med 17:210
2. Agabiti E, Todisco T, Grassi V, Sorbini CA (1973) Calculation of plasma bicarbonates using Henderson-Hasselbach equation. Influence of pK changes as a function of pH. Minerva Nefrol 20:23-7
3. 13C- magnetic resonance spectroscopy to studies of neuronal/glial relationships. Dev Neurosci 20:277-88
4. 13C]glucose MRS in chronic hepatic encephalopathy in man. Magn Reson Med 45:981-93
5. Bluml S, Moreno-Torres A, Shic F, Nguy CH, Ross BD (2002) Tricarboxylic acid cycle of glia in the in vivo human brain. NMR Biomed 15:1-5
6. Bluml S, Zuckerman E, Tan J, Ross BD (1998) Protondecoupled 31P magnetic resonance spectroscopy reveals osmotic and metabolic disturbances in human hepatic encephalopathy. J Neurochem 71:1564-76
7. Cerdan S (2003) 13C NMR and cerebral biochemistry. NMR Biomed 16:301-2
8. 13C NMR. J Biol Chem 265:12916-26
9. Cerdan S, Seelig J (1990) NMR studies of metabolism. Annu Rev Biophys Chem 19:43-67
10. 13C nuclear magnetic resonance. Endocrinology 136:296-305
11. Ernst T, Chang L, Leonido-Yee M, Speck O (2000) Evidence for long-term neurotoxicity associated with methamphetamine abuse: a 1H MRS study. Neurology 54:1344-1349
12. First MB, Frances AJ, Pincus HA, Vettorello N, Davis WW (1994) DSM-IV in progress. Changes in substancerelated, schizophrenic, and other primarily adult disorders. Hosp Community Psychiatry 45:18-20
13. Gass JT, Olive MF (2008) Glutamatergic substrates of drug addiction and alcoholism. Biochem Pharmacol 75:218-265
14. Gropman AL, Sailasuta N, Harris KC, Abulseoud O, Ross BD (2009) Ornithine transcarbamylase deficiency with persistent abnormality in cerebral glutamate metabolism in adults. Radiology 252:833-41
15. 13C nuclear magnetic resonance. Adv Exp Med Biol 331:35-40
16. Kalivas PW, Lalumiere RT, Knackstedt L, Shen H (2009) Glutamate transmission in addiction. Neuropharmacology 56 (Suppl 1) : 169-73
17. Kim SJ, Lyoo IK, Hwang J, Sung YH, Lee HY, Lee DS, Jeong DU, Renshaw PF (2005) Frontal glucose hypometabolism in abstinent methamphetamine users. Neuropsychopharmacology 30:1383-91 (Pubitemid 40848092)
18. Kim YT, Lee SW, Kwon DH, Seo JH, Ahn BC, Lee J (2009) Dose-dependent frontal hypometabolism on FDG-PET in methamphetamine abusers. J Psychiatr Res 43:1166-1170
19. 13C nuclear magnetic resonance spectroscopy: elucidation of the dominant pathway for neurotransmitter glutamate repletion and measurement of astrocytic oxidative metabolism. J Neurosci 22:1523-31
20. 13C MRS using very low RF power for proton decoupling. Magn Reson Med 57:265-71
21. Lin AP, Shic F, Enriquez C, Ross BD (2003) Reduced glutamate neurotransmission in patients with Alzheimer's disease-an in vivo (13) C magnetic resonance spectroscopy study. Magma 16:29-42
22. London ED, Ernst M, Grant S, Bonson K, Weinstein A (2000) Orbitofrontal cortex and human drug abuse: functional imaging. Cereb Cortex 10:334-42
23. London ED, Berman SM, Voytek B, Simon SL, Mandelkern MA, Monterosso J, Thompson PM, Brody AL, Geaga JA, Hong MS, Hayashi KM, Rawson RA, Ling W (2005) Cerebral metabolic dysfunction and impaired vigilance in recently abstinent methamphetamine abusers. Biol Psychiatry 58:770-8
24. Mason GF, Gruetter R, Rothman DL, Behar KL, Shulman RG, Novotny EJ (1995) Simultaneous determination of the rates of the TCA cycle, glucose utilization, alphaketoglutarate/glutamate exchange, and glutamine synthesis in human brain by NMR. J Cereb Blood Flow Metab 15:12-25
25. 13C] magnetic resonance spectroscopy at 4.1T. J Cereb Blood Flow Metab 19:1179-88
26. Moreno A, Bluml S, Hwang JH, Ross BD (2001) Alternative 1-(13) C glucose infusion protocols for clinical (13) C MRS examinations of the brain. Magn Reson Med 46:39-48
27. Muir D, Berl S, Clarke DD (1986) Acetate and fluoroacetate as possible markers for glial metabolism in vivo. Brain Res 380:336-40
28. Nordahl TE, Salo R, Natsuaki Y, Galloway GP, Waters C, Moore CD, Kile S, Buonocore MH (2005) Methamphetamine users in sustained abstinence: a proton magnetic resonance spectroscopy study. Arch Gen Psychiatry 62:444-52
29. Nordahl TE, Salo R, Possin K, Gibson DR, Flynn N, Leamon M, Galloway GP, Pfefferbaum A, Spielman DM, Adalsteinsson E, Sullivan EV (2002) Low N-acetyl-aspartate and high choline in the anterior cingulum of recently abstinent methamphetamine-dependent subjects: a preliminary proton MRS study. Magnetic resonance spectroscopy. Psychiatry Res 116:43-52
30. Rebec GV, Sun W (2005) Neuronal substrates of relapse to cocaine-seeking behavior: role of prefrontal cortex. J Exp Anal Behav 84:653-66 (Pubitemid 43339129)
31. Ross B, Lin A, Harris K, Bhattacharya P, Schweinsburg B (2003) Clinical experience with 13C MRS in vivo. NMR Biomed 16:358-69
32. Rothman DL, Behar KL, Hyder F, Shulman RG (2003) In vivo NMR studies of the glutamate neurotransmitter flux and neuroenergetics: implications for brain function. Annu Rev Physiol 65:401-27
33. Sailasuta N, Robertson LW, Harris KC, Gropman AL, Allen PS, Ross BD (2008) Clinical NOE 13C MRS for neuropsychiatric disorders of the frontal lobe. J Magn Reson 195:219-25
34. Salo R, Nordahl TE, Natsuaki Y, Leamon MH, Galloway GP, Waters C, Moore CD, Buonocore MH (2007) Attentional control and brain metabolite levels in methamphetamine abusers. Biol Psychiatry 61:1272-80
35. Sekine Y, Minabe Y, Kawai M, Suzuki K, Iyo M, Isoda H, Sakahara H, Ashby Jr CR., Takei N, Mori N (2002) Metabolite alterations in basal ganglia associated with methamphetamine-related psychiatric symptoms. A proton MRS study. Neuropsychopharmacology 27:453-461
36. 13C NMR. Proc Natl Acad Sci USA 96:8235-40
37. Shen J, Rothman DL (2002) Magnetic resonance spectroscopic approaches to studying neuronal:glial interactions. Biol Psychiatry 52:694-700
38. 13C MR spectra acquired from human brain in vivo. J Magn Reson 162:259-68
39. Siesjo BK (1964) The relation between the bicarbonate concentration in blood plasma and in brain tissue. Experientia 20:455-6
40. Stephans SE, Yamamoto BK (1994) Methamphetamineinduced neurotoxicity: roles for glutamate and dopamine efflux. Synapse 17:203-9
41. Sung YH, Cho SC, Hwang J, Kim SJ, Kim H, Bae S, Kim N, Chang KH, Daniels M, Renshaw PF, Lyoo IK (2007) Relationship between N-acetyl-aspartate in gray and white matter of abstinent methamphetamine abusers and their history of drug abuse: a proton magnetic resonance spectroscopy study. Drug Alcohol Depend 88:28-35
42. Volkow ND, Chang L, Wang GJ, Fowler JS, Franceschi D, Sedler M, Gatley SJ, Miller E, Hitzemann R, Ding YS, Logan J (2001) Loss of dopamine transporters in methamphetamine abusers recovers with protracted abstinence. J Neurosci 21:9414-8
43. Volkow ND, Fowler JS, Wang GJ, Goldstein RZ (2002) Role of dopamine, the frontal cortex and memory circuits in drug addiction: insight from imaging studies. Neurobiol Learn Mem 78:610-24
44. Wang GJ, Volkow ND, Chang L, Miller E, Sedler M, Hitzemann R, Zhu W, Logan J, Ma Y, Fowler JS (2004) Partial recovery of brain metabolism in methamphetamine abusers after protracted abstinence. Am J Psychiatry 161:242-8
45. Waniewski RA, Martin DL (1998) Preferential utilization of acetate by astrocytes is attributable to transport. J Neurosci 18:5225-33
46. Xu V, Chan H, Lin AP, Sailasuta N, Valencerina S, Tran T, Hovener J, Ross BD (2008) MR spectroscopy in diagnosis and neurological decision-making. Semin Neurol 28:407-22