1-Oxoeudesm-11(13)-ene-12,8α-lactone-induced apoptosis via ROS generation and mitochondria activation in MCF-7 cells

Archives of Pharmacal Research

Volumn 34, Issue 8, 2011, Pages 1323-1329

  Cui, Min ^a   Zhang, Yahong ^c   Liu, Shanshan ^a   Xie, Weidong ^a   Ji, Mei ^b   Lou, Hongxiang ^b   Li, Xia ^a,b  

^a SHANDONG UNIVERSITY   (China)

^b SHANDONG UNIVERSITY   (China)

^c HENAN UNIVERSITY   (China)

Author keywords

Apoptosis; Aster himalaicus; Eudesmane; MCF 7; OEL; ROS

Indexed keywords

1 OXOEUDESM 11(13) ENE 12,8ALPHA LACTONE; 3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; 4',6 DIAMIDINO 2 PHENYLINDOLE; ANTINEOPLASTIC AGENT; CASPASE 9; CYTOCHROME C; PHOSPHATIDYLSERINE; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; ASTER HIMALAICUS; CELL STRAIN; CELL STRAIN MCF 7; CELLULAR, SUBCELLULAR AND MOLECULAR BIOLOGICAL PHENOMENA AND FUNCTIONS; CHROMATIN CONDENSATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME MODIFICATION; EXTRACELLULAR SPACE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MITOCHONDRIA ACTIVATION; MITOCHONDRIAL MEMBRANE POTENTIAL; PROTEIN EXPRESSION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BREAST NEOPLASMS; CELL FRACTIONATION; CELL LINE, TUMOR; CELL SURVIVAL; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; HEPATOCYTES; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INDOLES; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; REACTIVE OXYGEN SPECIES; SESQUITERPENES, EUDESMANE; TETRAZOLIUM SALTS; THIAZOLES;

EID: 80855140924     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-011-0812-x     Document Type: Article

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