Effect of transmission reduction by insecticide-treated bednets (ITNs) on antimalarial drug resistance in Western Kenya

PLoS ONE

Volumn 6, Issue 11, 2011, Pages

  Shah, Monica ^a,b   Kariuki, Simon ^c   Vanden Eng, Jodi ^a   Blackstock, Anna J ^a,b   Garner, Kimberly ^b   Gatei, Wangeci ^a   Gimnig, John E ^a   Lindblade, Kim ^a   Terlouw, Dianne ^d   ter Kuile, Feiko ^d   Hawley, William A ^a,e   Phillips Howard, Penelope ^c,f   Nahlen, Bernard ^g   Walker, Edward ^h   Hamel, Mary J ^a,c   Slutsker, Laurence ^a   Shi, Ya Ping ^a  

^a CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^b ATLANTA RESEARCH AND EDUCATION FOUNDATION   (United States)

^c KENYA MEDICAL RESEARCH INSTITUTE   (Kenya)

^d LIVERPOOL SCHOOL OF TROPICAL MEDICINE   (United Kingdom)

^e UNICEF   (United States)

^f LIVERPOOL JOHN MOORES UNIVERSITY   (United Kingdom)

^g President's Malaria Initiative   (United States)

^h Michigan State University ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHLOROQUINE; INSECTICIDE; PYRIMETHAMINE PLUS SULFADOXINE; ANTIMALARIAL AGENT; CARRIER PROTEIN; MDR1 PROTEIN, PLASMODIUM FALCIPARUM; MULTIDRUG RESISTANCE PROTEIN; PFCRT PROTEIN, PLASMODIUM FALCIPARUM; PROTOZOAL PROTEIN; PYRIMETHAMINE; SULFADOXINE; SULFADOXINE-PYRIMETHAMINE;

ADULT; ANTIMALARIAL DRUG RESISTANCE; ARTICLE; BED NET; BLOOD SMEAR; CHILD; CONTROLLED STUDY; DISEASE SURVEILLANCE; FEMALE; GENE IDENTIFICATION; GENE LOCUS; GENE MUTATION; GENETIC ASSOCIATION; HUMAN; INSECT CONTROL; KENYA; MALE; MIXED INFECTION; NONHUMAN; PARASITE TRANSMISSION; PLASMODIUM FALCIPARUM; PRESCHOOL CHILD; SINGLE NUCLEOTIDE POLYMORPHISM; ADOLESCENT; CLINICAL TRIAL; DISEASE TRANSMISSION; DRUG COMBINATION; DRUG EFFECT; DRUG RESISTANCE; GENETICS; GENOTYPE; MALARIA FALCIPARUM; MULTIVARIATE ANALYSIS; MUTATION;

PLASMODIUM FALCIPARUM;

ADOLESCENT; ADULT; ANTIMALARIALS; CHILD; CHLOROQUINE; DRUG COMBINATIONS; DRUG RESISTANCE; FEMALE; GENOTYPE; HUMANS; INSECTICIDE-TREATED BEDNETS; KENYA; MALARIA, FALCIPARUM; MALE; MEMBRANE TRANSPORT PROTEINS; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; MULTIVARIATE ANALYSIS; MUTATION; PLASMODIUM FALCIPARUM; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTOZOAN PROTEINS; PYRIMETHAMINE; SULFADOXINE; YOUNG ADULT;

EID: 80855128831     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0026746     Document Type: Article

References (38)

1. World Health Organization (2009) World malaria report 2009 Geneva World Health Organization pp. xx,66.
2. Zimmerman PA, (2003) Roll back of Plasmodium falciparum antifolate resistance by insecticide-treated nets. Am J Trop Med Hyg 69: 236-237.
3. Hastings IM, Watkins WM, (2005) Intensity of malaria transmission and the evolution of drug resistance. Acta Trop 94: 218-229.
4. Wiseman V, Hawley WA, ter Kuile FO, Phillips-Howard PA, Vulule JM, et al. (2003) The cost-effectiveness of permethrin-treated bed nets in an area of intense malaria transmission in western Kenya. Am J Trop Med Hyg 68: 161-167.
5. Hill J, Lines J, Rowland M, (2006) Insecticide-treated nets. Adv Parasitol 61: 77-128.
6. Gimnig JE, Vulule JM, Lo TQ, Kamau L, Kolczak MS, et al. (2003) Impact of permethrin-treated bed nets on entomologic indices in an area of intense year-round malaria transmission. Am J Trop Med Hyg 68: 16-22.
7. Lengeler C, (2004) Insecticide-treated nets for malaria control: real gains. Bull World Health Organ 82: 84.
8. Gamble C, Ekwaru JP, ter Kuile FO, (2006) Insecticide-treated nets for preventing malaria in pregnancy. Cochrane Database Syst Rev pp. CD003755.
9. Alifrangis M, Lemnge MM, Ronn AM, Segeja MD, Magesa SM, et al. (2003) Increasing prevalence of wildtypes in the dihydrofolate reductase gene of Plasmodium falciparum in an area with high levels of sulfadoxine/pyrimethamine resistance after introduction of treated bed nets. Am J Trop Med Hyg 69: 238-243.
10. Mharakurwa S, Mutambu SL, Mudyiradima R, Chimbadzwa T, Chandiwana SK, et al. (2004) Association of house spraying with suppressed levels of drug resistance in Zimbabwe. Malar J 3: 35.
11. Diallo DA, Sutherland C, Nebie I, Konate AT, Ord R, et al. (2007) Sustained use of insecticide-treated curtains is not associated with greater circulation of drug-resistant malaria parasites, or with higher risk of treatment failure among children with uncomplicated malaria in Burkina Faso. Am J Trop Med Hyg 76: 237-244.
12. Talisuna AO, Okello PE, Erhart A, Coosemans M, D'Alessandro U, (2007) Intensity of malaria transmission and the spread of Plasmodium falciparum resistant malaria: a review of epidemiologic field evidence. Am J Trop Med Hyg 77: 170-180.
13. Talisuna AO, Erhart A, Samarasinghe S, Van Overmeir C, Speybroeck N, et al. (2006) Malaria transmission intensity and the rate of spread of chloroquine resistant Plasmodium falciparum: Why have theoretical models generated conflicting results? Infect Genet Evol 6: 241-248.
14. Talisuna AO, Langi P, Mutabingwa TK, Van Marck E, Speybroeck N, et al. (2003) Intensity of transmission and spread of gene mutations linked to chloroquine and sulphadoxine-pyrimethamine resistance in falciparum malaria. Int J Parasitol 33: 1051-1058.
15. Wongsrichanalai C, Pickard AL, Wernsdorfer WH, Meshnick SR, (2002) Epidemiology of drug-resistant malaria. Lancet Infect Dis 2: 209-218.
16. Kublin JG, Dzinjalamala FK, Kamwendo DD, Malkin EM, Cortese JF, et al. (2002) Molecular markers for failure of sulfadoxine-pyrimethamine and chlorproguanil-dapsone treatment of Plasmodium falciparum malaria. J Infect Dis 185: 380-388.
17. Figueiredo P, Benchimol C, Lopes D, Bernardino L, do Rosario VE, et al. (2008) Prevalence of pfmdr1, pfcrt, pfdhfr and pfdhps mutations associated with drug resistance, in Luanda, Angola. Malar J 7: 236.
18. Lindblade KA, Eisele TP, Gimnig JE, Alaii JA, Odhiambo F, et al. (2004) Sustainability of reductions in malaria transmission and infant mortality in western Kenya with use of insecticide-treated bednets: 4 to 6 years of follow-up. JAMA 291: 2571-2580.
19. Phillips-Howard PA, ter Kuile FO, Nahlen BL, Alaii JA, Gimnig JE, et al. (2003) The efficacy of permethrin-treated bed nets on child mortality and morbidity in western Kenya II. Study design and methods. Am J Trop Med Hyg 68: 10-15.
20. ter Kuile FO, Terlouw DJ, Phillips-Howard PA, Hawley WA, Friedman JF, et al. (2003) Impact of permethrin-treated bed nets on malaria and all-cause morbidity in young children in an area of intense perennial malaria transmission in western Kenya: cross-sectional survey. Am J Trop Med Hyg 68: 100-107.
21. Singer LM, Mirel LB, ter Kuile FO, Branch OH, Vulule JM, et al. (2003) The effects of varying exposure to malaria transmission on development of antimalarial antibody responses in preschool children. XVI. Asembo Bay Cohort Project. J Infect Dis 187: 1756-1764.
22. ter Kuile FO, Terlouw DJ, Kariuki SK, Phillips-Howard PA, Mirel LB, et al. (2003) Impact of permethrin-treated bed nets on malaria, anemia, and growth in infants in an area of intense perennial malaria transmission in western Kenya. Am J Trop Med Hyg 68: 68-77.
23. Phillips-Howard PA, Wannemuehler KA, ter Kuile FO, Hawley WA, Kolczak MS, et al. (2003) Diagnostic and prescribing practices in peripheral health facilities in rural western Kenya. Am J Trop Med Hyg 68: 44-49.
24. Alker AP, Mwapasa V, Meshnick SR, (2004) Rapid real-time PCR genotyping of mutations associated with sulfadoxine-pyrimethamine resistance in Plasmodium falciparum. Antimicrob Agents Chemother 48: 2924-2929.
25. Purfield A, Nelson A, Laoboonchai A, Congpuong K, McDaniel P, et al. (2004) A new method for detection of pfmdr1 mutations in Plasmodium falciparum DNA using real-time PCR. Malar J 3: 9.
26. Wilson PE, Kazadi W, Kamwendo DD, Mwapasa V, Purfield A, et al. (2005) Prevalence of pfcrt mutations in Congolese and Malawian Plasmodium falciparum isolates as determined by a new Taqman assay. Acta Trop 93: 97-106.
27. Hastings IM, Nsanzabana C, Smith TA, (2010) A comparison of methods to detect and quantify the markers of antimalarial drug resistance. Am J Trop Med Hyg 83: 489-495.
28. Menegon M, Talha AA, Severini C, Elbushra SM, Mohamedani AA, et al. (2010) Frequency distribution of antimalarial drug resistance alleles among Plasmodium falciparum isolates from Gezira State, central Sudan, and Gedarif State, eastern Sudan. Am J Trop Med Hyg 83: 250-257.
29. Osman ME, Mockenhaupt FP, Bienzle U, Elbashir MI, Giha HA, (2007) Field-based evidence for linkage of mutations associated with chloroquine (pfcrt/pfmdr1) and sulfadoxine-pyrimethamine (pfdhfr/pfdhps) resistance and for the fitness cost of multiple mutations in P. falciparum. Infect Genet Evol 7: 52-59.
30. Gatei W, Kariuki S, Hawley W, ter Kuile F, Terlouw D, et al. (2010) Effects of transmission reduction by insecticide-treated bed nets (ITNs) on parasite genetics population structure: I. The genetic diversity of Plasmodium falciparum parasites by microsatellite markers in western Kenya. Malar J 9: 353.
31. Iyer JK, Milhous WK, Cortese JF, Kublin JG, Plowe CV, (2001) Plasmodium falciparum cross-resistance between trimethoprim and pyrimethamine. Lancet 358: 1066-1067.
32. Terlouw DJ, Nahlen BL, Courval JM, Kariuki SK, Rosenberg OS, et al. (2003) Sulfadoxine-pyrimethamine in treatment of malaria in Western Kenya: increasing resistance and underdosing. Antimicrob Agents Chemother 47: 2929-2932.
33. Spalding MD, Eyase FL, Akala HM, Bedno SA, Prigge ST, et al. (2010) Increased prevalence of the pfdhfr/phdhps quintuple mutant and rapid emergence of pfdhps resistance mutations at codons 581 and 613 in Kisumu, Kenya. Malar J 9: 338.
34. Hamel MJ, Greene C, Chiller T, Ouma P, Polyak C, et al. (2008) Does cotrimoxazole prophylaxis for the prevention of HIV-associated opportunistic infections select for resistant pathogens in Kenyan adults? Am J Trop Med Hyg 79: 320-330.
35. Malisa AL, Pearce RJ, Abdulla S, Mshinda H, Kachur PS, et al. (2010) Drug coverage in treatment of malaria and the consequences for resistance evolution-evidence from the use of sulphadoxine/pyrimethamine. Malar J 9: 190.
36. Hastings IM, D'Alessandro U, (2000) Modelling a predictable disaster: the rise and spread of drug-resistantmalaria. Parasitol Today 16: 340-347.
37. Laufer MK, Thesing PC, Eddington ND, Masonga R, Dzinjalamala FK, et al. (2006) Return of chloroquine antimalarial efficacy in Malawi. N Engl J Med 355: 1959-1966.
38. Kublin JG, Cortese JF, Njunju EM, Mukadam RA, Wirima JJ, et al. (2003) Reemergence of chloroquine-sensitive Plasmodium falciparum malaria after cessation of chloroquine use in Malawi. J Infect Dis 187: 1870-1875.