Adolescent neurobehavioral characteristics, alcohol sensitivities, and intake: Setting the stage for alcohol use disorders?

Child Development Perspectives

Volumn 5, Issue 4, 2011, Pages 231-238

  Spear, Linda Patia ^a  

^a BINGHAMTON UNIVERSITY   (United States)

Author keywords

Adolescent; Alcohol; Animal models; Aversive stimuli; Brain development; Rewarding stimuli; Social facilitation

Indexed keywords

EID: 80855124033     PISSN: 17508592     EISSN: 17508606     Source Type: Journal    
DOI: 10.1111/j.1750-8606.2011.00182.x     Document Type: Review

References (88)

1. Aberg, M., Wade, D., Wall, E., & Izenwasser, S. (2007). Effect of MDMA (ecstasy) on activity and cocaine conditioned place preference in adult and adolescent rats. Neurotoxicology and Teratology, 29, 37-46.
2. Acheson, S. K., Stein, R. M., & Swartzwelder, H. S. (1998). Impairment of semantic and figural memory by acute ethanol: Age-dependent effects. Alcoholism: Clinical and Experimental Research, 22, 1437-1442.
3. Ahlström, S. K., & Österberg, E. L. (2004). International perspectives on adolescent and young adult drinking. Alcohol Research and Health, 28, 258-268.
4. Badanich, K. A., Adler, K. J., & Kirstein, C. L. (2006). Adolescents differ from adults in cocaine conditioned place preference and cocaine-induced dopamine in the nucleus accumbens septi. European Journal of Pharmacology, 550, 95-106.
5. Beck, K. H., Thombs, D. L., & Summons, T. G. (1993). The social context of drinking scales: Construct validation and relationship to indicants of abuse in an adolescent population. Addictive Behaviors, 18, 159-169.
6. Begleiter, H., & Porjesz, B. (1999). What is inherited in the predisposition toward alcoholism: A proposed model? Alcoholism: Clinical and Experimental Research, 23, 1125-1135.
7. Behar, D., Berg, C. J., Rapoport, J. L., Nelson, W., Linnoila, M., Cohen, M., et al. (1983). Behavioral and physiological effects of ethanol in high-risk and control children: A pilot study. Alcoholism: Clinical and Experimental Research, 7, 404-410.
8. Bell, R. L., Rodd, Z. A., Sable, H. J. K., Schultz, J. A., Hsu, C. C., Lumeng, L., et al. (2006). Daily patterns of ethanol drinking in peri-adolescent and adult alcohol-preferring (P) rats. Pharmacology, Biochemistry and Behavior, 83, 35-46.
9. Benes, F. M., Turtle, M., Khan, Y., & Farol, P. (1994). Myclination of key relay zone the hippocampal formation occurs in the human brain during childhood, adolescence, and adulthood. Archives of General Psychiatry, 51, 477-484.
10. Berridge, K. C., & Kringelbach, M. L. (2008). Affective neuroscience of pleasure: Reward in humans and animals. Psychopharmacology, 199, 457-480.
11. Brenhouse, H. C., & Andersen, S. L. (2008). Delayed extinction and stronger reinstatement of cocaine conditioned place preference in adolescent rats, compared to adults. Behavioral Neuroscience, 122, 460-465.
12. Brooks-Kayal, A. R., Shumate, M. D., Rikhter, T. Y., Kelly, M. E., & Coulter, D. A. (2001). Gamma-aminobutyric acid(A) receptor subunit expression predicts functional changes in hippocampal dentate granule cells during postnatal development. Journal of Neuroscience, 77, 1266-1278.
13. Casey, B. J., Getz, S., & Galvan, A. (2008). The adolescent brain. Developmental Review, 28, 62-77.
14. Cha, Y. M., White, A. M., Kuhn, C. M., Wilson, W. A., & Swartzwelder, H. S. (2006). Differential effects of delta9-THC on learning in adolescent and adult rats. Pharmacology, Biochemistry and Behavior, 83, 448-455.
15. Clark, D. B., Thatcher, D. L., & Tapert, S. F. (2008). Alcohol, psychological dysregulation, and adolescent brain development. Alcoholism: Clinical and Experimental Research, 32, 1-11.
16. Crews, F. T., Braun, C. J., Hoplight, B., Switzer III, R. C., & Knapp, D. J. (2000). Binge ethanol consumption causes differential brain damage in young adolescent rats compared with adult rats. Alcoholism: Clinical and Experimental Research, 24, 1712-1723.
17. Dawson, D. A., Grant, B. F., & Li, T.-K. (2007). Impact of age at first drink on stress-reactive drinking. Alcoholism: Clinical and Experimental Research, 31, 69-77.
18. De Bellis, M. D., Narasimhan, A., Thatcher, D. L., Keshavan, M. S., Soloff, P., & Clark, D. B. (2005). Prefrontal cortex, thalamus, and cerebellar volumes in adolescents and young adults with adolescent-onset alcohol use disorders and comorbid mental disorders. Alcoholism: Clinical and Experimental Research, 29, 1590-1600.
19. Dick, D. M. (in press). Developmental changes in genetic influences on alcohol use and dependence. Child Development Perspectives, XX, XXX-XXX.
20. Dickinson, S. D., Kashawny, S. K., Thiebes, K. P., & Charles, D. Y. (2009). Decreased sensitivity to ethanol reward in adolescent mice as measured by conditioned place preference. Alcoholism: Clinical and Experimental Research, 33(7), 1-6.
21. Doremus, T. L., Brunell, S. C., Rajendran, P., & Spear, L. P. (2005). Factors influencing elevated ethanol consumption in adolescent relative to adult rats. Alcoholism: Clinical and Experimental Research, 29, 1796-1808.
22. Doremus-Fitzwater, T. L., & Spear, L. P. (2007). Developmental differences in acute ethanol withdrawal in adolescent and adult rats. Alcoholism: Clinical and Experimental Research, 31, 1-12.
23. Doremus-Fitzwater, T. L., Varlinskaya, E. I., & Spear, L. P. (2010). Motivational systems in adolescence: Possible implications for age differences in substance abuse and other risk-taking behaviors. Brain and Cognition, 72, 114-123.
24. Douglas, L. A., Varlinskaya, E. I., & Spear, L. P. (2003). Novel object place conditioning in adolescent and adult male and female rats: Effects of social isolation. Physiology and Behavior, 80, 317-325.
25. Douglas, L. A., Varlinskaya, E. I., & Spear, L. P. (2004). Rewarding properties of social interactions in adolescent and adult male and female rats: Impact of social versus isolate housing of subjects and partners. Developmental Psychobiology, 45, 153-162.
26. Eckardt, M. J., File, S. E., Gessa, G. L., Grant, K. A., Guerri, C., Hoffman, P. L., et al. (1998). Effects of moderate alcohol consumption on the central nervous system. Alcoholism: Clinical and Experimental Research, 22, 998-1040.
27. Ehlers, C. L., Slutske, W. S., Gilder, D. A., Lau, P., & Wilhelmsen, K. C. (2006). Age at first intoxication and alcohol use disorders in Southwest California Indians. Alcoholism: Clinical and Experimental Research, 30, 1856-1865.
28. Enright, R. D., Levy Jr, V. M., Harris, D., & Lapsley, D. K. (1987). Do economic conditions influence how theorists view adolescents? Journal of Youth and Adolescence, 16, 541-559.
29. A receptor-mediated inhibition in dentate gyrus changes from adolescence to adulthood. Journal of Neurophysiology, 97, 3806-3811.
30. Gardner, M., & Steinberg, L. (2005). Peer influence on risk taking, risk preference, and risky decision making in adolescence and adulthood: An experimental study. Developmental Psychology, 41, 625-635.
31. Gogtay, N., Giedd, J. N., Lusk, L., Hayashi, K. M., Greenstein, D., Vaituzis, A. C., et al. (2004). Dynamic mapping of human cortical development during childhood through early adulthood. Proceedings of the National Academy of Sciences, 101, 8174-8179.
32. Grant, B. F., & Dawson, D. A. (1997). Age at onset of alcohol use and its association with DSM-IV alcohol abuse and dependence: Results from the National Longitudinal Alcohol Epidemiologic Survey. Journal of Substance Abuse, 9, 103-110.
33. Grant, B. F., Harford, T. C., Muthen, B. O., Yi, H.-Y., Hasin, D. S., & Stinson, F. S. (2007). DSM-IV alcohol dependence and abuse: Further evidence of validity in the general population. Drug and Alcohol Dependence, 86, 154-166.
34. Green, A. S., & Grahame, N. J. (2008). Ethanol drinking in rodents: Is free-choice drinking related to the reinforcing effects of ethanol? Alcohol, 42(1), 1-11.
35. Hargreaves, G. A., Quinn, H., Kashem, M. A., Matsumoto, I., & McGregor, I. S. (2008). Proteomic analysis demonstrates adolescent vulnerability to lasting hippocampal changes following chronic alcohol consumption. Alcoholism: Clinical and Experimental Research, 32(11), 1-9.
36. Infurna, R. N., & Spear, L. P. (1979). Developmental changes in amphetamine-induced taste aversions. Pharmacology Biochemistry and Behavior, 11, 31-35.
37. Johnston, L. D., O'Malley, P. M., Bachman, J. G., & Schulenberg, J. E. (2008). Monitoring the future; national results on adolescent drug use. Overview of key findings, 2007 (NIH Publication No. 08-6418).
38. Kasanetz, F., & Manzoni, O. J. (2009). Maturation of excitatory synaptic transmission of the rat nucleus accumbens from juvenile to adult. Journal of Neurophysiology, 101, 2516-2527.
39. Lenroot, R. K., & Giedd, J. N. (2006). Brain development in children and adolescents: Insights from anatomical magnetic resonance imaging. Neuroscience and Biobehavioral Reviews, 30, 718-729.
40. Lenroot, R. K., Gogtay, N., Greenstein, D. K., Wells, G. L., Clasen, L. S., Blumenthal, J. D., et al. (2007). Sexual dimorphism of brain developmental trajectories during childhood and adolescence. Neuroimage, 36, 1065-1073.
41. Li, Q., Wilson, W. A., & Swartzwelder, H. S. (2002). Differential effect of ethanol on NMDA EPSCs in pyramidal cells in the posterior cingulate cortex of juvenile and adult rats. Journal of Neurophysiology, 87, 705-711.
42. Markwiese, B. J., Acheson, S. K., Levin, E. D., Wilson, W. A., & Swartzwelder, H. S. (1998). Differential effects of ethanol on memory in adolescent and adult rats. Alcoholism: Clinical and Experimental Research, 22, 416-421.
43. McBride, W. J., & Li, T.-K. (1998). Animal models of alcoholism: Neurobiology of high alcohol-drinking behavior in rodents. Pharmacology, Biochemistry and Behavior, 71, 509-515.
44. Mellanby, E. (1919). Alcohol: Its absorption into and disappearance from the blood under different conditions (Special Report Series No. 31, National Research Council). London: Medical Research Committee.
45. Moy, S. S., Duncan, G. E., Knapp, D. J., & Breese, G. R. (1998). Sensitivity to ethanol across development in rats: Comparison to [3H] zolpidem binding. Alcoholism: Clinical and Experimental Research, 22, 1485-1492.
46. Odgers, C. L., Caspi, A., Nagin, D. S., Piquero, A. R., Slutske, W. S., Milne, B. J., et al. (2008). Is it important to prevent early exposure to drugs and alcohol among adolescents? Psychological Science, 19, 1037-1044.
47. Østby, Y., Tamnes, C. K., Fjell, A. M., Westlye, L. T., Due-Tonnessen, P., & Walhovd, K. B. (2009). Heterogeneity in subcortical brain development: A structural magnetic resonance imaging study of brain maturation from 8 to 30years. Journal of Neuroscience, 29, 11772-11782.
48. Pautassi, R. M., Myers, M., Spear, L. P., Molina, J. C., & Spear, N. E. (2008). Adolescent, but not adult, rats exhibit ethanol-mediated appetitive second-order conditioning. Alcoholism: Clinical and Experimental Research, 32, 1-12.
49. Pyapali, G., Turner, D., Wilson, W., & Swartzwelder, H. (1999). Age and dose-dependent effects of ethanol on the induction of hippocampal long-term potentiation. Alcohol, 19, 107-111.
50. Rakic, P., Bourgeois, J.-P., & Goldman-Rakic, P. S. (1994). Synaptic development of the cerebral cortex: Implications for learning, memory, and mental illness. In J. van Pelt, M. A. Corner, H. B. M. Uylings, & F. H. Lopes da Silva (Eds.), The self-organizing brain: From growth cones to functional networks (Vol. 102, pp. 227-243). Amsterdam: Elsevier Science.
51. Ristuccia, R. C., & Spear, L. P. (2008). Autonomic responses to ethanol in adolescent and adult rats: A dose-response analysis. Alcohol, 42, 623-629.
52. Rodd-Henricks, Z. A., Bell, R. L., Kuc, K. A., Murphy, J. M., McBride, W. J., Lumeng, L., et al. (2002). Effects of ethanol exposure on subsequent acquisition and extinction of ethanol self-administration and expression of alcohol-seeking behavior in adult alcohol-preferring (P) rats: I. Periadolescent exposure. Alcoholism: Clinical and Experimental Research, 26, 1632-1641.
53. Rubia, K., Smith, A. B., Taylor, E., & Brammer, M. (2007). Linear age-correlated functional development of right inferior fronto-otriato-cerebellar networks during response inhibition and anterior cingulate during error-related processes. Human Brain Mapping, 27, 973-993.
54. Sabeti, J., & Gruol, D. L. (2008). Emergence of NMDAR-independent long-term potentiation at hippocampal CA1 synapses following early adolescent exposure to chronic intermittent ethanol: Role for sigma-receptors. Hippocampus, 18, 148-168.
55. Salami, M., Itami, C., Tsumoto, T., & Kimura, F. (2003). Change of conduction velocity by regional myelination yields constant latency irrespective of distance between thalamus and cortex. Proceedings of the National Academy of Sciences, 100, 6174-6179.
56. Schlegel, A. (2009) Cross-cultural issues in the study of adolescent development. In R. M. Lerner & L. Steinberg (Eds.), Handbook of Adolescent Psychology: Vol. 2. Contextual influences on adolescent development (pp. 570-589). Hoboken, NJ: Wiley.
57. Schramm-Sapyta, N. L., Cha, Y. M., Chaudhry, S., Wilson, W. A., Swartzwelder, H. S., & Kuhn, C. M. (2007). Differential anxiogenic, aversive, and locomotor effects of THC in adolescent and adult rats. Psychopharmacology, 191, 867-877.
58. Schuckit, M. A. (1994). Low level of response to alcohol as a predictor of future alcoholism. American Journal of Psychiatry, 151, 184-189.
59. Shram, M. J., Funk, D., Li, X., & Le, A. D. (2006). Periadolescent and adult rats respond differently in tests measuring the rewarding and aversive effects of nicotine. Psychopharmacology, 186, 201-208.
60. Silveri, M. M., & Spear, L. P. (1998). Decreased sensitivity to the hypnotic effects of ethanol early in ontogeny. Alcoholism: Clinical and Experimental Research, 22, 670-676.
61. Silveri, M. M., & Spear, L. P. (2001). Acute, rapid and chronic tolerance during ontogeny: Observations when equating ethanol perturbation across age. Alcoholism: Clinical and Experimental Research, 25, 1301-1308.
62. A pharmacological manipulations on ethanol sensitivity in immature and mature animals. Alcoholism: Clinical and Experimental Research, 26, 449-456.
63. A pharmacological manipulations on acute and rapid tolerance to ethanol during ontogeny. Alcoholism: Clinical and Experimental Research, 28, 884-894.
64. Slotkin, T. A. (2002). Nicotine and the adolescent brain: Insights from an animal model. Neurotoxicology and Teratology, 24, 369-384.
65. Sowell, E., Thompson, P., Peterson, B., Mattson, S., Welcome, S., Henkenius, A., et al. (2002). Mapping cortical gray matter asymmetry patterns in adolescents with heavy prenatal alcohol exposure. Neuroimage, 17, 1807-1819.
66. Spear, L. P. (2000). The adolescent brain and age-related behavioral manifestations. Neuroscience and Biobehavioral Reviews, 24, 417-463.
67. Spear, L. P. (2007). Assessment of adolescent neurotoxicity: Rationale and methodological considerations. Neurotoxicology and Teratology, 29, 1-9.
68. Spear, L. P. (2010). The behavioral neuroscience of adolescence. New York: W.W. Norton.
69. Spear, L. P., & Varlinskaya, E. I. (2005). Low dose effects in psychopharmacology: Ontogenetic considerations. Nonlinearity in Biology, Toxicology and Medicine, 3, 97-111.
70. Squeglia, L. M., Jacobus, J., & Taper, S. F. (2009). The influence of substance use on adolescent brain development. Clinical EEG and Neuroscience, 40, 31-38.
71. Steinberg, L. (2005). Cognitive and affective development in adolescence. Trends in Cognitive Sciences, 9, 69-74.
72. Steinberg, L. (2008). A social neuroscience perspective on adolescence. Trends in Cognitive Science, 9, 69-74.
73. Substance Abuse and Mental Health Services Administration. (2006). Results from the 2005 National Survey on Drug Use and Health: National findings (National Survey on Drug use and Health Series H-30, DHHS publication SMA 06-4194). Rockville, MD: Author.
74. Tapert, S. F., & Schweinsburg, A. D. (2005). The human adolescent brain and alcohol use disorders. In M. Galanter (Ed.), Recent developments in alcoholism: Vol. 17. Alcohol problems in adolescents and young adults (pp. 177-197). New York: Kluwer Academic/Plenum.
75. Torres, O. V., Tejeda, H. A., Natividad, L. A., & O'Dell, L. E. (2008). Enhanced vulnerability to the rewarding effects of nicotine during the adolescent period of development. Pharmacology, Biochemistry and Behavior, 90, 658-663.
76. Varlinskaya, E. I., & Spear, L. P. (2004). Acute ethanol withdrawal (hangover) and social behavior in adolescent and adult male and female Sprague-Dawley rats. Alcoholism: Clinical and Experimental Research, 28, 40-50.
77. Varlinskaya, E. I., & Spear, L. P. (2006). Ontogeny of acute tolerance to ethanol-induced social inhibition in Sprague-Dawley rats. Alcoholism: Clinical and Experimental Research, 30, 1833-1844.
78. Varlinskaya, E. I., & Spear, L. P. (2007). Chronic tolerance to the social consequences of ethanol in adolescent and adult Sprague-Dawley rats. Neurotoxicology and Teratology, 29, 23-30.
79. Varlinskaya, E. I., & Spear, L. P. (2009). Ethanol-induced social facilitation in adolescent rats: Role of endogenous activity at mu opioid receptors. Alcoholism: Clinical and Experimental Research, 33, 991-1000.
80. Vastola, B. J., Douglas, L. A., Varlinskaya, E. I., & Spear, L. P. (2002). Nicotine-induced conditioned place preference in adolescent and adult rats. Physiology & Behavior, 77, 107-114.
81. Vetter, C. S., Doremus-Fitzwater, T. L., & Spear, L. P. (2007). Time-course of elevated ethanol intake in adolescent relative to adult rats under continuous, voluntary-access conditions. Alcoholism: Clinical and Experimental Research, 31, 1159-1168.
82. Vetter-O'Hagen, C., Varlinskaya, E. I., & Spear, L. (2009). Sex differences in ethanol intake and sensitivity to aversive effects during adolescence and adulthood. Alcohol and Alcoholism, 44, 547-554.
83. White, A. M., Roberts, D. C., & Best, P. J. (2002). Context-specific tolerance to the ataxic effects of alcohol. Pharmacology Biochemistry and Behavior, 72, 107-110.
84. Wilmouth, C. E., & Spear, L. P. (2009). Hedonic sensitivity in adolescent and adult rats: Taste reactivity and voluntary sucrose consumption. Pharmacology, Biochemistry and Behavior, 92, 566-573.
85. Young, S. Y. N., Hansen, C. J., Gibson, R. L., & Ryan, M. A. K. (2006). Risky alcohol use, age at onset of drinking, and adverse childhood experiences in young men entering the US Marine Corps. Archives of Pediatric and Adolescent Medicine, 160, 1207-1214.
86. A receptor subunit distribution during brain maturation and aging. Brain Research, 1099, 73-81.
87. Zakharova, E., Leoni, G., Kichko, I., & Izenwasser, S. (2009). Differential effects of methamphetamine, cocaine on conditioned place preference and locomotor activity in adult and adolescent male rats. Behavioural Brain Research, 198, 45-50.
88. Zucker, R. A., Heitzeg, M. M., & Nigg, J. T. (2011). Parsing the undercontrol-disinhibition pathway to substance use disorders: A multilevel developmental problem. Child Development Perspectives, 5, 248-255.