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Volumn 459, Issue 4, 2011, Pages 367-375

The role of tumor hypoxia in MUC1-positive breast carcinomas

Author keywords

Breast cancer; HIF 1 ; Hypoxia; MUC1; NF B; Tissue microarray

Indexed keywords

CARBONATE DEHYDRATASE IX; ESTROGEN RECEPTOR; HYPOXIA INDUCIBLE FACTOR 1; I KAPPA B KINASE ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MUCIN 1; PROGESTERONE RECEPTOR; PROTEIN P53; VASCULOTROPIN;

EID: 80855123672     PISSN: 09456317     EISSN: 14322307     Source Type: Journal    
DOI: 10.1007/s00428-011-1142-6     Document Type: Article
Times cited : (21)

References (41)
  • 1
    • 33644845663 scopus 로고    scopus 로고
    • Expression of checkpoint kinase 2 in breast carcinomas: Correlation with key regulators of tumor cell proliferation, angiogenesis, and survival
    • 16437383 1:CAS:528:DC%2BD28Xls1Srsrw%3D
    • A Ribeiro-Silva MA Moutinho HB Moura, et al. 2006 Expression of checkpoint kinase 2 in breast carcinomas: correlation with key regulators of tumor cell proliferation, angiogenesis, and survival Histol Histopathol 21 373 382 16437383 1:CAS:528:DC%2BD28Xls1Srsrw%3D
    • (2006) Histol Histopathol , vol.21 , pp. 373-382
    • Ribeiro-Silva, A.1    Moutinho, M.A.2    Moura, H.B.3
  • 2
    • 77953672808 scopus 로고    scopus 로고
    • Relationships between hypoxia markers and the leptin system, estrogen receptors in human primary and metastatic breast cancer: Effects of preoperative chemotherapy
    • 10.1186/1471-2407-10-320
    • M Koda L Kanczuga-Koda M Sulkowska, et al. 2010 Relationships between hypoxia markers and the leptin system, estrogen receptors in human primary and metastatic breast cancer: effects of preoperative chemotherapy BMC Cancer 10 1 8 10.1186/1471-2407-10-320
    • (2010) BMC Cancer , vol.10 , pp. 1-8
    • Koda, M.1    Kanczuga-Koda, L.2    Sulkowska, M.3
  • 3
    • 77954473120 scopus 로고    scopus 로고
    • The saponin monomer of dwarf lilyturf tuber, DT-13, reduces human breast cancer cell adhesion and migration during hypoxia via regulation of tissue factor
    • 20606312 10.1248/bpb.33.1192 1:CAS:528:DC%2BC3cXhtFert7vJ
    • L Sun S Lin R Zhao, et al. 2010 The saponin monomer of dwarf lilyturf tuber, DT-13, reduces human breast cancer cell adhesion and migration during hypoxia via regulation of tissue factor Biol Pharm Bull 33 1192 1198 20606312 10.1248/bpb.33.1192 1:CAS:528:DC%2BC3cXhtFert7vJ
    • (2010) Biol Pharm Bull , vol.33 , pp. 1192-1198
    • Sun, L.1    Lin, S.2    Zhao, R.3
  • 4
    • 77955097923 scopus 로고    scopus 로고
    • Hypoxia-specific targets in cancer therapy: Role of splice variants
    • D Vordermark 2010 Hypoxia-specific targets in cancer therapy: role of splice variants BMC Med 12 1 3
    • (2010) BMC Med , vol.12 , pp. 1-3
    • Vordermark, D.1
  • 5
    • 77954564670 scopus 로고    scopus 로고
    • Hypoxia and metabolic phenotypes during breast carcinogenesis: Expression of HIF-1α, GLUT1, and CAIX
    • 20526721 10.1007/s00428-010-0938-0 1:CAS:528:DC%2BC3cXotlyqt70%3D
    • CL Chen JS Chu WC Su 2010 Hypoxia and metabolic phenotypes during breast carcinogenesis: expression of HIF-1α, GLUT1, and CAIX Virchows Arch 457 53 61 20526721 10.1007/s00428-010-0938-0 1:CAS:528:DC%2BC3cXotlyqt70%3D
    • (2010) Virchows Arch , vol.457 , pp. 53-61
    • Chen, C.L.1    Chu, J.S.2    Su, W.C.3
  • 6
    • 0035503362 scopus 로고    scopus 로고
    • Expression of hypoxia-inducible carbonic anhydrase-9 relates to angiogenic pathways and independently to poor outcome in non-small cell lung cancer
    • A Giatromanolaki MI Koukourakis E Sivridis, et al. 2001 Expression of hypoxia-inducible carbonic anhydrase-9 relates to angiogenic pathways and independently to poor outcome in non-small cell lung cancer Cancer Res 61 7992 7998 11691824 1:CAS:528:DC%2BD3MXotlars7s%3D (Pubitemid 33049392)
    • (2001) Cancer Research , vol.61 , Issue.21 , pp. 7992-7998
    • Giatromanolaki, A.1    Koukourakis, M.I.2    Sivridis, E.3    Pastorek, J.4    Wykoff, C.C.5    Gatter, K.C.6    Harris, A.L.7
  • 7
    • 0031985662 scopus 로고    scopus 로고
    • Immunohistochemical detection of the MUC1 gene product in human cancers grown in scid mice
    • U Schumacher E Adam 1998 Immunohistochemical detection of the MUC1 gene product in human cancers grown in scid mice J Histochem Cytochem 46 127 134 9405502 10.1177/002215549804600116 1:CAS:528:DyaK1cXlsVGi (Pubitemid 28030518)
    • (1998) Journal of Histochemistry and Cytochemistry , vol.46 , Issue.1 , pp. 127-134
    • Schumacher, U.1    Adam, E.2
  • 8
    • 25144504517 scopus 로고    scopus 로고
    • Expression of mucins (MUC1, MUC2, MUC3, MUC4, MUC5AC and MUC6) and their prognostic significance in human breast cancer
    • DOI 10.1038/modpathol.3800445, PII 3800445
    • EA Rakha WG Boyce DA El-Rehim, et al. 2005 Expression of mucins (MUC1, MUC2, MUC3, MUC4, MUC5AC and MUC6) and their prognostic significance in human breast cancer Mod Pathol 18 1295 1304 15976813 10.1038/modpathol.3800445 1:CAS:528:DC%2BD2MXhtVWiu7fN (Pubitemid 41348648)
    • (2005) Modern Pathology , vol.18 , Issue.10 , pp. 1295-1304
    • Rakha, E.A.1    Boyce, R.W.G.2    El-Rehim, D.A.3    Kurien, T.4    Green, A.R.5    Paish, E.C.6    Robertson, J.F.R.7    Ellis, I.O.8
  • 9
    • 0031701559 scopus 로고    scopus 로고
    • Altered mucin expression is a field change that accompanies mucinous (colloid) breast carcinoma histogenesis
    • JT O'Connell S Zhi-Ming D Ehud, et al. 1998 Altered mucin expression is a field change that accompanies mucinous (colloid) breast carcinoma histogenesis Hum Pathol 29 1517 1523 9865841 10.1016/S0046-8177(98)90024-7 (Pubitemid 28563988)
    • (1998) Human Pathology , vol.29 , Issue.12 , pp. 1517-1523
    • O'Connell, J.T.1    Shao, Z.-M.2    Drori, E.3    Basbaum, C.B.4    Barsky, S.H.5
  • 10
    • 67449127094 scopus 로고    scopus 로고
    • Direct targeting of the mucin 1 oncoprotein blocks survival and tumorigenicity of human breast carcinoma cells
    • 19491255 10.1158/0008-5472.CAN-09-0854 1:CAS:528:DC%2BD1MXnt1equrg%3D
    • D Raina R Ahmad MD Joshi, et al. 2009 Direct targeting of the mucin 1 oncoprotein blocks survival and tumorigenicity of human breast carcinoma cells Cancer Res 69 5133 5141 19491255 10.1158/0008-5472.CAN-09-0854 1:CAS:528:DC%2BD1MXnt1equrg%3D
    • (2009) Cancer Res , vol.69 , pp. 5133-5141
    • Raina, D.1    Ahmad, R.2    Joshi, M.D.3
  • 11
  • 14
    • 0141955228 scopus 로고    scopus 로고
    • An anti-MUC1-antibody - Interleukin-2 fusion protein that activates resting NK cells to lysis of MUC1-positive tumour cells
    • DOI 10.1038/sj.bjc.6601267
    • C Heuser M Ganser A Hombach, et al. 2003 An anti-MUC1-antibody- interleukin-2 fusion protein that activates resting NK cells to lysis of MUC1-positive tumour cells Br J Cancer 89 1130 1139 12966437 10.1038/sj.bjc.6601267 1:CAS:528:DC%2BD3sXntVKnsrk%3D (Pubitemid 37243025)
    • (2003) British Journal of Cancer , vol.89 , Issue.6 , pp. 1130-1139
    • Heuser, C.1    Ganser, M.2    Hombach, A.3    Brand, H.4    Denton, G.5    Hanisch, F.-G.6    Abken, H.7
  • 15
    • 33745942997 scopus 로고    scopus 로고
    • MUC1 alters oncogenic events and transcription in human breast cancer cells
    • DOI 10.1186/bcr1515
    • CL Hattrup SJ Gendler 2006 MUC1 alters oncogenic events and transcription in human breast cancer cells Breast Cancer Res 8 R37 16846534 10.1186/bcr1515 (Pubitemid 44057562)
    • (2006) Breast Cancer Research , vol.8 , Issue.4
    • Hattrup, C.L.1    Gendler, S.J.2
  • 16
    • 66149151809 scopus 로고    scopus 로고
    • MUC1-induced transcriptional programs associated with tumorigenesis predict outcome in breast and lung cancer
    • 19318547 10.1158/0008-5472.CAN-08-4513 1:CAS:528:DC%2BD1MXjvVWis74%3D
    • NN Khodarev SP Pitroda MA Beckett, et al. 2009 MUC1-induced transcriptional programs associated with tumorigenesis predict outcome in breast and lung cancer Cancer Res 69 2833 2837 19318547 10.1158/0008-5472.CAN-08-4513 1:CAS:528:DC%2BD1MXjvVWis74%3D
    • (2009) Cancer Res , vol.69 , pp. 2833-2837
    • Khodarev, N.N.1    Pitroda, S.P.2    Beckett, M.A.3
  • 17
    • 35648951666 scopus 로고    scopus 로고
    • MUC1 expression is repressed by protein inhibitor of activated signal transducer and activator of transcription-y
    • DOI 10.1210/me.2006-0539
    • MJ Brayman N Dharmaraj E Lagow, et al. 2007 MUC1 expression is repressed by protein inhibitor of activated signal transducer and activator of transcription-y Mol Endocrinol 21 2725 2737 17717071 10.1210/me.2006-0539 1:CAS:528:DC%2BD2sXht1ynsrfO (Pubitemid 350035154)
    • (2007) Molecular Endocrinology , vol.21 , Issue.11 , pp. 2725-2737
    • Brayman, M.J.1    Dharmaraj, N.2    Lagow, E.3    Carson, D.D.4
  • 18
    • 65649099349 scopus 로고    scopus 로고
    • A potent, imaging adenoviral vector driven by the cancer-selective mucin-1 promoter that targets breast cancer metastasis
    • 19366829 10.1158/1078-0432.CCR-08-2666 1:CAS:528:DC%2BD1MXltFOrtbg%3D
    • ST Huyn JB Burton M Sato, et al. 2009 A potent, imaging adenoviral vector driven by the cancer-selective mucin-1 promoter that targets breast cancer metastasis Clin Cancer Res 15 3126 3134 19366829 10.1158/1078-0432.CCR-08-2666 1:CAS:528:DC%2BD1MXltFOrtbg%3D
    • (2009) Clin Cancer Res , vol.15 , pp. 3126-3134
    • Huyn, S.T.1    Burton, J.B.2    Sato, M.3
  • 19
    • 0042818006 scopus 로고    scopus 로고
    • Human MUC1 carcinoma antigen regulates intracellular oxidant levels and the apoptotic response to oxidative stress
    • DOI 10.1074/jbc.M301987200
    • L Yin Y Li J Ren, et al. 2003 Human MUC1 carcinoma antigen regulates intracellular oxidant levels and the apoptotic response to oxidative stress J Biol Chem 278 35458 3564 12826677 10.1074/jbc.M301987200 1:CAS:528: DC%2BD3sXntVajsr0%3D (Pubitemid 37102316)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.37 , pp. 35458-35464
    • Yin, L.1    Li, Y.2    Ren, J.3    Kuwahara, H.4    Kufe, D.5
  • 20
    • 0029801151 scopus 로고    scopus 로고
    • Breast cancer immunotherapy: Current status and future prospects
    • V Apostolopoulos IF Mckenzie GA Pietersz 1996 Breast cancer immunotherapy: current status and future prospects Immunol Cell Biol 74 457 464 8912009 10.1038/icb.1996.76 1:CAS:528:DyaK28XmvFKmsbs%3D (Pubitemid 26342131)
    • (1996) Immunology and Cell Biology , vol.74 , Issue.5 , pp. 457-464
    • Apostolopoulos, V.1    McKenzie, I.F.C.2    Pietersz, G.A.3
  • 21
    • 0009941731 scopus 로고    scopus 로고
    • Prognostic factors in breast cancer. College of American Pathologists Consensus Statement 1999
    • 10888772 1:STN:280:DC%2BD3czptVKrtQ%3D%3D
    • PL Fitzgibbons DL Page D Weaver, et al. 2000 Prognostic factors in breast cancer. College of American Pathologists Consensus Statement 1999 Arch Pathol Lab Med 124 966 978 10888772 1:STN:280:DC%2BD3czptVKrtQ%3D%3D
    • (2000) Arch Pathol Lab Med , vol.124 , pp. 966-978
    • Fitzgibbons, P.L.1    Page, D.L.2    Weaver, D.3
  • 22
    • 60549088737 scopus 로고    scopus 로고
    • BRCA1 expression and molecular alterations in familial breast cancer
    • 19012246 1:STN:280:DC%2BD1cjksVCjtw%3D%3D
    • A Mangia A Chiriatti S Tommasi, et al. 2009 BRCA1 expression and molecular alterations in familial breast cancer Histol Histopathol 24 69 76 19012246 1:STN:280:DC%2BD1cjksVCjtw%3D%3D
    • (2009) Histol Histopathol , vol.24 , pp. 69-76
    • Mangia, A.1    Chiriatti, A.2    Tommasi, S.3
  • 23
    • 77950690403 scopus 로고    scopus 로고
    • Epidermal growth factor receptor and vascular endothelial growth factor receptor 2 are specific biomarkers in triple-negative breast cancer. Results from a controlled randomized trial with long-term follow-up
    • 20135347 10.1007/s10549-010-0758-6
    • L Rydén K Jirstro M Haglund, et al. 2010 Epidermal growth factor receptor and vascular endothelial growth factor receptor 2 are specific biomarkers in triple-negative breast cancer. Results from a controlled randomized trial with long-term follow-up Breast Cancer Res Treat 120 491 498 20135347 10.1007/s10549-010-0758-6
    • (2010) Breast Cancer Res Treat , vol.120 , pp. 491-498
    • Rydén, L.1    Jirstro, K.2    Haglund, M.3
  • 24
    • 67349136325 scopus 로고    scopus 로고
    • Immunohistochemical comparison of MUC1, CA125, and Her2Neu in invasive micropapillary carcinoma of the urinary tract and typical invasive urothelial carcinoma with retraction artifact
    • 19270645 10.1038/modpathol.2009.16 1:CAS:528:DC%2BD1MXlt1SltLc%3D
    • AR Sangoi JP Higgins RV Rouse, et al. 2009 Immunohistochemical comparison of MUC1, CA125, and Her2Neu in invasive micropapillary carcinoma of the urinary tract and typical invasive urothelial carcinoma with retraction artifact Mod Pathol 22 660 667 19270645 10.1038/modpathol.2009.16 1:CAS:528: DC%2BD1MXlt1SltLc%3D
    • (2009) Mod Pathol , vol.22 , pp. 660-667
    • Sangoi, A.R.1    Higgins, J.P.2    Rouse, R.V.3
  • 25
    • 0141678107 scopus 로고    scopus 로고
    • Revision of breast cancer staging: The 6th edition of the TNM Classification
    • DOI 10.1002/ssu.10021
    • SE Singletary FL Greene 2003 Revision of breast cancer staging: the 6th edition of the TNM classification Semin Surg Oncol 21 53 59 12923916 10.1002/ssu.10021 (Pubitemid 37127474)
    • (2003) Seminars in Surgical Oncology , vol.21 , Issue.1 , pp. 53-59
    • Singletary, S.E.1    Greene, F.L.2
  • 26
    • 0036022141 scopus 로고    scopus 로고
    • Synergistic stimulation of MUC1 expression in normal breast epithelia and breast cancer cells by interferon-γ and tumor necrosis factor-α
    • DOI 10.1002/jcb.10261
    • EL Lagow DD Carson 2002 Synergistic stimulation of MUC1 expression in normal breast epithelia and breast cancer cells by interferon-γ and tumor necrosis factor-α J Cell Biochem 86 759 772 12210742 10.1002/jcb.10261 1:CAS:528:DC%2BD38XmtVOhurs%3D (Pubitemid 34839977)
    • (2002) Journal of Cellular Biochemistry , vol.86 , Issue.4 , pp. 759-772
    • Lagow, E.L.1    Carson, D.D.2
  • 27
    • 36749092728 scopus 로고    scopus 로고
    • MUC1 oncoprotein activates the IκB kinase β complex and constitutive NF-κB signalling
    • DOI 10.1038/ncb1661, PII NCB1661
    • R Ahmad D Raina V Trivedi, et al. 2007 MUC1 oncoprotein activates the IκB kinase β complex and constitutive NF-κB signalling Nat Cell Biol 9 1419 1427 18037881 10.1038/ncb1661 1:CAS:528:DC%2BD2sXhtlOns7bN (Pubitemid 350201755)
    • (2007) Nature Cell Biology , vol.9 , Issue.12 , pp. 1419-1427
    • Ahmad, R.1    Raina, D.2    Trivedi, V.3    Ren, J.4    Rajabi, H.5    Kharbanda, S.6    Kufe, D.7
  • 28
    • 0032566317 scopus 로고    scopus 로고
    • Estrogen receptor does not directly regulate the murine Muc-1 promoter
    • DOI 10.1016/S0303-7207(98)00141-5, PII S0303720798001415
    • X Zhou MM DeSouza J Julian, et al. 1998 Estrogen receptor does not directly regulate the murine Muc-1 promoter Mol Cell Endocrinol 143 65 78 9806351 10.1016/S0303-7207(98)00141-5 1:CAS:528:DyaK1cXls1yjsb8%3D (Pubitemid 28458743)
    • (1998) Molecular and Cellular Endocrinology , vol.143 , Issue.1-2 , pp. 65-78
    • Zhou, X.1    DeSouza, M.M.2    Julian, J.3    Gendler, S.J.4    Carson, D.D.5
  • 29
    • 71549131622 scopus 로고    scopus 로고
    • Slight activation of nuclear factor kappa-B is associated with increased hepatic stellate cell apoptosis in human schistosomal fibrosis
    • 19781518 10.1016/j.actatropica.2009.09.008 1:CAS:528:DC%2BD1MXhtlyjtr7O
    • MM Braz FS Ramalho RL Cardoso, et al. 2010 Slight activation of nuclear factor kappa-B is associated with increased hepatic stellate cell apoptosis in human schistosomal fibrosis Acta Trop 113 66 71 19781518 10.1016/j.actatropica. 2009.09.008 1:CAS:528:DC%2BD1MXhtlyjtr7O
    • (2010) Acta Trop , vol.113 , pp. 66-71
    • Braz, M.M.1    Ramalho, F.S.2    Cardoso, R.L.3
  • 31
    • 0037352170 scopus 로고    scopus 로고
    • Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: A target for cancer chemotherapy
    • DOI 10.1038/sj.leu.2402824
    • F Chang JT Lee PM Navolanic, et al. 2003 Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: a target for cancer chemotherapy Leukemia 17 590 603 12646949 10.1038/sj.leu.2402824 1:CAS:528:DC%2BD3sXitFentb0%3D (Pubitemid 36395654)
    • (2003) Leukemia , vol.17 , Issue.3 , pp. 590-603
    • Chang, F.1    Lee, J.T.2    Navolanic, P.M.3    Steelman, L.S.4    Shelton, J.G.5    Blalock, W.L.6    Franklin, R.A.7    McCubrey, J.A.8
  • 32
    • 77957940286 scopus 로고    scopus 로고
    • Significance of topoisomerase IIIβ expression in breast ductal carcinomas: Strong associations with disease-specific survival and metastasis
    • 20950730 10.1016/j.humpath.2010.01.027 1:CAS:528:DC%2BC3cXhtlSqurnM
    • JP Oliveira-Costa J Zanetti LR Oliveira, et al. 2010 Significance of topoisomerase IIIβ expression in breast ductal carcinomas: strong associations with disease-specific survival and metastasis Hum Pathol 41 1624 1630 20950730 10.1016/j.humpath.2010.01.027 1:CAS:528:DC%2BC3cXhtlSqurnM
    • (2010) Hum Pathol , vol.41 , pp. 1624-1630
    • Oliveira-Costa, J.P.1    Zanetti, J.2    Oliveira, L.R.3
  • 33
    • 27244443082 scopus 로고    scopus 로고
    • Proliferation marker Ki-67 in early breast cancer
    • 16192605 10.1200/JCO.2005.07.501 1:CAS:528:DC%2BD2MXhtFCrsbfK
    • A Urruticoechea IE Smith M Dowsett 2005 Proliferation marker Ki-67 in early breast cancer J Clin Oncol 23 7212 7220 16192605 10.1200/JCO.2005.07.501 1:CAS:528:DC%2BD2MXhtFCrsbfK
    • (2005) J Clin Oncol , vol.23 , pp. 7212-7220
    • Urruticoechea, A.1    Smith, I.E.2    Dowsett, M.3
  • 34
    • 77954761483 scopus 로고    scopus 로고
    • Suppression of hypoxia-induced HIF-1a accumulation by VEGFR inhibitors: Different profiles of AAL993 versus SU5416 and KRN633
    • 20378243 10.1016/j.canlet.2010.03.010 1:CAS:528:DC%2BC3cXovFymsLc%3D
    • HS Ban M Uno H Nakamura 2010 Suppression of hypoxia-induced HIF-1a accumulation by VEGFR inhibitors: different profiles of AAL993 versus SU5416 and KRN633 Cancer Lett 296 17 26 20378243 10.1016/j.canlet.2010.03.010 1:CAS:528:DC%2BC3cXovFymsLc%3D
    • (2010) Cancer Lett , vol.296 , pp. 17-26
    • Ban, H.S.1    Uno, M.2    Nakamura, H.3
  • 35
    • 78549245097 scopus 로고    scopus 로고
    • NF-kB mediates aberrant activation of HIF-1 in malignant lymphoma
    • 10.1016/j.exphem.2010.08.007 1:CAS:528:DC%2BC3cXhsVGnsLrL
    • Q Qiao Y Nozaki K Sakoe, et al. 2010 NF-kB mediates aberrant activation of HIF-1 in malignant lymphoma Exp Hemathol 38 1199 1208 10.1016/j.exphem.2010. 08.007 1:CAS:528:DC%2BC3cXhsVGnsLrL
    • (2010) Exp Hemathol , vol.38 , pp. 1199-1208
    • Qiao, Q.1    Nozaki, Y.2    Sakoe, K.3
  • 36
    • 79951676430 scopus 로고    scopus 로고
    • Ras regulates interleukin-1β-induced HIF-1α transcriptional activity in glioblastoma
    • 20865400 10.1007/s00109-010-0683-5 1:CAS:528:DC%2BC3MXntVCqsA%3D%3D
    • V Sharma D Dixit N Koul, et al. 2011 Ras regulates interleukin-1β- induced HIF-1α transcriptional activity in glioblastoma J Mol Med 89 123 136 20865400 10.1007/s00109-010-0683-5 1:CAS:528:DC%2BC3MXntVCqsA%3D%3D
    • (2011) J Mol Med , vol.89 , pp. 123-136
    • Sharma, V.1    Dixit, D.2    Koul, N.3
  • 37
    • 78149316509 scopus 로고    scopus 로고
    • Adenomatous polyposis coli and hypoxia-inducible factor-1α have an antagonistic connection
    • 20844082 10.1091/mbc.E10-04-0312 1:CAS:528:DC%2BC3cXhsFWhs7rL
    • IP Newton NS Kenneth PL Appleton, et al. 2010 Adenomatous polyposis coli and hypoxia-inducible factor-1α have an antagonistic connection Mol Biol Cell 21 3630 3638 20844082 10.1091/mbc.E10-04-0312 1:CAS:528:DC%2BC3cXhsFWhs7rL
    • (2010) Mol Biol Cell , vol.21 , pp. 3630-3638
    • Newton, I.P.1    Kenneth, N.S.2    Appleton, P.L.3
  • 38
    • 67649525776 scopus 로고    scopus 로고
    • Angiogenesis in pre-malignant conditions
    • 19406633 10.1016/j.ejca.2009.04.007 1:CAS:528:DC%2BD1MXotFCjs7g%3D
    • M Raica AM Cimpeana D Ribatti 2009 Angiogenesis in pre-malignant conditions Eur J Cancer 45 1924 1934 19406633 10.1016/j.ejca.2009.04.007 1:CAS:528:DC%2BD1MXotFCjs7g%3D
    • (2009) Eur J Cancer , vol.45 , pp. 1924-1934
    • Raica, M.1    Cimpeana, A.M.2    Ribatti, D.3
  • 39
    • 67649881466 scopus 로고    scopus 로고
    • Effect of raloxifene on vascular endothelial growth factor expression in breast carcinomas of postmenopausal women
    • 19489979 10.1111/j.1365-2184.2009.00615.x
    • BB Silva AR Santos CG Pires, et al. 2009 Effect of raloxifene on vascular endothelial growth factor expression in breast carcinomas of postmenopausal women Cell Prolif 42 506 510 19489979 10.1111/j.1365-2184.2009.00615.x
    • (2009) Cell Prolif , vol.42 , pp. 506-510
    • Silva, B.B.1    Santos, A.R.2    Pires, C.G.3
  • 40
    • 0034071994 scopus 로고    scopus 로고
    • Coexpression of MUC1 glycoprotein with multiple angiogenic factors in non-small cell lung cancer suggests coactivation of angiogenic and migration pathways
    • A Giatromanolaki MI Koukourakis E Sivridis, et al. 2000 Coexpression of MUC1 glycoprotein with multiple angiogenic factors in non-small cell lung cancer suggests coactivation of angiogenic and migration pathways Clin Cancer Res 6 1917 1921 10815916 1:CAS:528:DC%2BD3cXktVWisLc%3D (Pubitemid 30305090)
    • (2000) Clinical Cancer Research , vol.6 , Issue.5 , pp. 1917-1921
    • Giatromanolaki, A.1    Koukourakis, M.I.2    Sivridis, E.3    O'Byrne, K.4    Cox, G.5    Thorpe, P.E.6    Gatter, K.C.7    Harris, A.L.8
  • 41
    • 68749119335 scopus 로고    scopus 로고
    • Angiogenesis is associated with the onset of hyperplasia in human ductal breast disease
    • 19623180 10.1038/sj.bjc.6605196 1:CAS:528:DC%2BD1MXpvFyisLg%3D
    • JE Bluff SR Menakuru SS Cross, et al. 2009 Angiogenesis is associated with the onset of hyperplasia in human ductal breast disease Br J Cancer 101 666 672 19623180 10.1038/sj.bjc.6605196 1:CAS:528:DC%2BD1MXpvFyisLg%3D
    • (2009) Br J Cancer , vol.101 , pp. 666-672
    • Bluff, J.E.1    Menakuru, S.R.2    Cross, S.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.