Immunohistochemical comparison of MUC1, CA125, and Her2Neu in invasive micropapillary carcinoma of the urinary tract and typical invasive urothelial carcinoma with retraction artifact

Modern Pathology

Volumn 22, Issue 5, 2009, Pages 660-667

  Sangoi, Ankur R ^a   Higgins, John P ^a   Rouse, Robert V ^a,b   Schneider, Anne G ^c   McKenney, Jesse K ^a,c,d  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VA PALO ALTO HEALTH CARE SYSTEM   (United States)

^c UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^d STANFORD UNIVERSITY   (United States)

Author keywords

CA125; Her2Neu; Immunohistochemistry; Micropapillary; MUC1; Urinary

Indexed keywords

BIOLOGICAL MARKER; CA 125 ANTIGEN; CANCER ANTIBODY; EPIDERMAL GROWTH FACTOR RECEPTOR 2; MUCIN 1; TUMOR MARKER;

ADULT; AGED; ARTICLE; BLADDER CARCINOMA; BREAST CARCINOMA; CLINICAL ARTICLE; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOPHENOTYPING; IMMUNOREACTIVITY; INVASIVE CARCINOMA; MALE; PAPILLARY CARCINOMA; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; URINARY TRACT CARCINOMA; URINARY TRACT MICROPAPILLARY CARCINOMA; UROTHELIUM;

AGED; AGED, 80 AND OVER; ARTIFACTS; CA-125 ANTIGEN; CARCINOMA, PAPILLARY; CARCINOMA, TRANSITIONAL CELL; DIAGNOSIS, DIFFERENTIAL; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; IMMUNOPHENOTYPING; MALE; MIDDLE AGED; MUCIN-1; NEOPLASM STAGING; RECEPTOR, ERBB-2; SENSITIVITY AND SPECIFICITY; TUMOR MARKERS, BIOLOGICAL; URINARY BLADDER NEOPLASMS;

EID: 67349136325     PISSN: 08933952     EISSN: 15300285     Source Type: Journal    
DOI: 10.1038/modpathol.2009.16     Document Type: Article

References (29)

1. Amin MB, Ro JY, el-Sharkawy T, et al. Micropapillary variant of transitional cell carcinoma of the urinary bladder. Histologic pattern resembling ovarian papillary serous carcinoma. Am J Surg Pathol 1994;18: 1224-1232.
2. Amin MB, Tamboli P, Merchant SH, et al. Micropapillary component in lung adenocarcinoma: a distinctive histologic feature with possible prognostic significance. Am J Surg Pathol 2002;26:358-364.
3. Nagao T, Gaffey TA, Visscher DW, et al. Invasive micropapillary salivary duct carcinoma: a distinct histologic variant with biologic significance. Am J Surg Pathol 2004;28:319-326.
4. Nassar H. Carcinomas with micropapillary morphology: clinical significance and current concepts. Adv Anat Pathol 2004;11:297-303.
5. Sakamoto K, Watanabe M, De La Cruz C, et al. Primary invasive micropapillary carcinoma of the colon. Histopathology 2005;47:479-484.
6. Siriaunkgul S, Tavassoli FA. Invasive micropapillary carcinoma of the breast. Mod Pathol 1993;6:660-662.
7. Alvarado-Cabrero I, Sierra-Santiesteban FI, Mantilla- Morales A, et al. Micropapillary carcinoma of the urothelial tract. A clinicopathologic study of 38 cases. Ann Diagn Pathol 2005;9:1-5.
8. Munakata S, Tahara H, Kojima K, et al. Micropapillary urothelial carcinoma of the renal pelvis: report of a case and review of the literature. Med Sci Monit 2007;13:CS47-CS52.
9. Oh YL, Kim KR. Micropapillary variant of transitional cell carcinoma of the ureter. Pathol Int 2000;50: 52-56.
10. Perez-Montiel D, Hes O, Michal M, et al. Micropapillary urothelial carcinoma of the upper urinary tract: clinicopathologic study of five cases. Am J Clin Pathol 2006;126:86-92.
11. Perez-Montiel D, Wakely PE, Hes O, et al. High-grade urothelial carcinoma of the renal pelvis: clinicopathologic study of 108 cases with emphasis on unusual morphologic variants. Mod Pathol 2006;19:494-503.
12. Vang R, Abrams J. A micropapillary variant of transitional cell carcinoma arising in the ureter. Arch Pathol Lab Med 2000;124:1347-1348.
13. Johansson SL, Borghede G, Holmang S. Micropapillary bladder carcinoma: a clinicopathological study of 20 cases. J Urol 1999;161:1798-1802.
14. Kuroda N, Tamura M, Ohara M, et al. Invasive micropapillary carcinoma of the urinary bladder: an immunohistochemical study of neoplastic and stromal cells. Int J Urol 2006;13:1015-1018.
15. Maranchie JK, Bouyounes BT, Zhang PL, et al. Clinical and pathological characteristics of micropapillary transitional cell carcinoma: a highly aggressive variant. J Urol 2000;163:748-751.
16. Nassar H, Pansare V, Zhang H, et al. Pathogenesis of invasive micropapillary carcinoma: role of MUC1 glycoprotein. Mod Pathol 2004;17:1045-1050.
17. Ohtsuki Y, Ochi K, Okada Y, et al. Micropapillary component of urothelial carcinoma detected in transurethral resection of bladder tumor (TUR-BT) tissues: a case report. Med Mol Morphol 2008;41:113-116.
18. Regalado JJ. Mixed micropapillary and trophoblastic carcinoma of bladder: report of a first case with new immunohistochemical evidence of urothelial origin. Hum Pathol 2004;35:382-384.
19. Samaratunga H, Khoo K. Micropapillary variant of urothelial carcinoma of the urinary bladder; a clinicopathological and immunohistochemical study. Histopathology 2004;45:55-64.
20. Zhang HSR, Ali-Fehmi R, Bianco F, et al. Characteristic immunohistochemical profiles and aggressive behavior of micropapillary and other histological variants and subtypes of urothelial carcinoma. Mod Pathol 2004;17(Suppl 1):186A (782).
21. Wolff AC, Hammond ME, Schwartz JN, et al. American society of clinical oncology/college of American pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer. Arch Pathol Lab Med 2007;131:18.
22. Zhai QJ, Black J, Ayala AG, et al. Histologic variants of infiltrating urothelial carcinoma. Arch Pathol Lab Med 2007;131:1244-1256.
23. Kamat AM, Dinney CP, Gee JR, et al. Micropapillary bladder cancer: a review of the University of Texas M. D. Anderson Cancer Center experience with 100 consecutive patients. Cancer 2007;110:62-67.
24. Kamat AM, Gee JR, Dinney CP, et al. The case for early cystectomy in the treatment of nonmuscle invasive micropapillary bladder carcinoma. J Urol 2006;175: 881-885.
25. McKenney J. News in brief: the clinical management of 'superficial' (pT1/cT1) micropapillary carcinoma of the urinary bladder: are times changing? Adv Anat Pathol 2007;14:444-445.
26. McKenney JK, Gomez JA, Desai S, et al. Morphologic expressions of urothelial carcinoma in situ: a detailed evaluation of its histologic patterns with emphasis on carcinoma in situ with microinvasion. Am J Surg Pathol 2001;25:356-362.
27. Luna-More S, Gonzalez B, Acedo C, et al. Invasive micropapillary carcinoma of the breast. A new special type of invasive mammary carcinoma. Pathol Res Pract 1994;190:668-674.
28. Acs G, Dumoff KL, Solin LJ, et al. Extensive retraction artifact correlates with lymphatic invasion and nodal metastasis and predicts poor outcome in early stage breast carcinoma. Am J Surg Pathol 2007;31:129-140.
29. Acs G, Paragh G, Chuang ST, et al. The presence of micropapillary features and retraction artifact in core needle biopsy material predicts lymph node metastasis in breast carcinoma. Am J Surg Pathol 2009;33: 202-210.