Cilostazol inhibits matrix invasion and modulates the gene expressions of MMP-9 and TIMP-1 in PMA-differentiated THP-1 cells

European Journal of Pharmacology

Volumn 670, Issue 2-3, 2011, Pages 419-426

  Chuang, Shih Yi ^a   Yang, Su Hui ^a   Chen, Tzi Ya ^a   Pang, Jong Hwei S ^a  

^a CHANG GUNG UNIVERSITY   (Taiwan)

Author keywords

Atherosclerosis; Cilostazol; Invasion; MMP 9; THP 1; TIMP 1

Indexed keywords

CILOSTAZOL; CYCLIC AMP; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PHORBOL 12 ACETATE 13 MYRISTATE; RNA; TISSUE INHIBITOR OF METALLOPROTEINASE 1;

ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; ENZYME ACTIVITY; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; MACROPHAGE; MONOCYTE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING; ZYMOGRAPHY;

ACTIVE TRANSPORT, CELL NUCLEUS; AMP-ACTIVATED PROTEIN KINASES; ATHEROSCLEROSIS; CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL NUCLEUS; CYCLIC AMP; ENZYME INHIBITORS; EXTRACELLULAR MATRIX; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MACROPHAGES; MATRIX METALLOPROTEINASE 9; MONOCYTES; NF-KAPPA B; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; RNA, MESSENGER; TETRADECANOYLPHORBOL ACETATE; TETRAZOLES; TISSUE INHIBITOR OF METALLOPROTEINASE-1; TUNICA INTIMA;

EID: 80755189998     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2011.08.040     Document Type: Article

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