Tandem mass spectrometric characterization of thiol peptides modified by the chemoselective cationic sulfhydryl reagent (4-iodobutyl) triphenylphosphonium - Effects of a cationic thiol derivatization on peptide fragmentation

Journal of the American Society for Mass Spectrometry

Volumn 22, Issue 10, 2011, Pages 1771-1783

  Wang, Jing ^a   Zhang, Jie ^a   Arbogast, Brian ^a   Maier, Claudia S ^a  

^a OREGON STATE UNIVERSITY   (United States)

Author keywords

Fixed charge modification; Peptide fragmentation; Proline effect; Thiol specific modification

Indexed keywords

ALKYLATION REAGENTS; AMIDE BOND; CHARGE STATE; CHEMOSELECTIVE; CLEAVAGE SITES; COLLISION-INDUCED DISSOCIATION; CYSTEINE RESIDUES; DERIVATIZATIONS; FIXED CHARGES; IMPACT FRAGMENTATION; LOW ENERGIES; PEPTIDE BACKBONES; PEPTIDE FRAGMENTATION; PHOSPHONIUM MOIETY; PROLINE EFFECT; PROTON AFFINITY; QUADRUPOLES; RELATIVE ABUNDANCE; SULFHYDRYL; TANDEM MASS SPECTROMETRIC; TANDEM MASS SPECTROMETRY; THIOL GROUPS; THIOL PEPTIDES; THIOL-SPECIFIC MODIFICATION; TIME OF FLIGHT;

AMIDES; AMINO ACIDS; CAMS; CHEMICAL BONDS; CHEMICAL MODIFICATION; MASS SPECTROMETERS; MASS SPECTROMETRY; POSITIVE IONS;

PEPTIDES;

(4 IODOBUTYL)TRIPHENYLPHOSPHONIUM; ALANINE; ALANYLCYSTYLALANYLALANINE; ALANYLCYSTYLALANYLPROLYLALANINE; ALANYLPROLYLALANYLCYSTYLALANINE; BUTYLTRIPHENYLPHOSPHONIUM; CYSTEINE; PEPTIDE FRAGMENT; PHOSPHINE DERIVATIVE; PROLINE; THIOL PROTEINASE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CHEMICAL ANALYSIS; CHEMICAL BOND; CHEMICAL STRUCTURE; COLLISIONALLY ACTIVATED DISSOCIATION; CONTROLLED STUDY; DERIVATIZATION; FRAGMENTATION REACTION; NONHUMAN; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MODIFICATION; PROTEIN MOTIF; PROTON TRANSPORT; RAT; TANDEM MASS SPECTROMETRY;

AMINO ACID SEQUENCE; ANIMALS; CATIONS; MOLECULAR SEQUENCE DATA; ONIUM COMPOUNDS; ORGANOPHOSPHORUS COMPOUNDS; PEPTIDE FRAGMENTS; PROLINE; RATS; SULFHYDRYL COMPOUNDS; TANDEM MASS SPECTROMETRY;

EID: 80755159120     PISSN: 10440305     EISSN: 18791123     Source Type: Journal    
DOI: 10.1007/s13361-011-0192-y     Document Type: Article

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