Computational investigation and hydrogen/deuterium exchange of the fixed charge derivative tris(2,4,6-trimethoxyphenyl) phosphonium: Implications for the aspartic acid cleavage mechanism

Journal of the American Society for Mass Spectrometry

Volumn 16, Issue 7, 2005, Pages 1067-1080

  Herrmann, Kristin A ^a   Wysocki, Vicki H ^a   Vorpagel, Erich R ^b  

^a University of Arizona   (United States)

^b PACIFIC NORTHWEST NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CHARGE TRANSFER; CONFORMATIONS; DEUTERIUM; ESTERS; HYDROGEN BONDS; MOLECULAR VIBRATIONS; OPTIMIZATION;

ASPARTIC ACID; ELECTROSTATIC POTENTIAL; HYDROGEN/DEUTERIUM EXCHANGE; PROTONATION;

ION EXCHANGE;

ASPARTIC ACID; DEUTERIUM; ESTER DERIVATIVE; HYDROGEN; PEPTIDE; PHOSPHONIUM DERIVATIVE; PROTON; TRIS(2,4,6 TRIMETHOXYPHENYL)PHOSPHONIUM; UNCLASSIFIED DRUG;

AB INITIO CALCULATION; ACIDITY; AMINO ACID ANALYSIS; ARTICLE; CARBOXY TERMINAL SEQUENCE; DEGRADATION KINETICS; DERIVATIZATION; DEUTERIUM HYDROGEN EXCHANGE; ELECTRICITY; FRAGMENTATION REACTION; GEOMETRY; HYDROGEN BOND; MOLECULAR INTERACTION; MOLECULAR MODEL; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN MOTIF; PROTEOMICS; PROTON TRANSPORT; SEPARATION TECHNIQUE; TRANSPORT KINETICS;

AMINO ACID SEQUENCE; ASPARTIC ACID; COMPUTATIONAL BIOLOGY; CYCLOTRONS; DEUTERIUM; HYDROGEN; MOLECULAR SEQUENCE DATA; ORGANOPHOSPHORUS COMPOUNDS; PEPTIDES; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROSCOPY, FOURIER TRANSFORM INFRARED;

EID: 20444457125     PISSN: 10440305     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jasms.2005.03.028     Document Type: Article

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