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Volumn 13, Issue 6, 2011, Pages 521-527

Recent advances in the understanding of genetic susceptibility to chronic pain and somatic symptoms

Author keywords

Chronic pain; Chronic widespread pain; Fibromyalgia; Genetic susceptibility; Genetics; Heritability; Low back pain; Polymorphism; Somatic symptoms; Susceptibility

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR; CATECHOL METHYLTRANSFERASE; CORTICOTROPIN RECEPTOR; GUANOSINE TRIPHOSPHATE CYCLOHYDROLASE I; MU OPIATE RECEPTOR; POTASSIUM CHANNEL KV9.1; PROOPIOMELANOCORTIN; SEROTONIN 2A RECEPTOR; SEROTONIN TRANSPORTER; SODIUM CHANNEL NAV1.7; TRANSCORTIN; UNCLASSIFIED DRUG; VOLTAGE GATED POTASSIUM CHANNEL;

EID: 80755136554     PISSN: 15233774     EISSN: 15346307     Source Type: Journal    
DOI: 10.1007/s11926-011-0208-4     Document Type: Article
Times cited : (30)

References (50)
  • 1
    • 47249138323 scopus 로고    scopus 로고
    • Localized or widespread musculoskeletal pain: Does it matter?
    • 18077092 10.1016/j.pain.2007.11.002
    • Y Kamaleri B Natvig CM Ihlebaek D Bruusgaard 2008 Localized or widespread musculoskeletal pain: does it matter? Pain 138 41 46 18077092 10.1016/j.pain.2007.11.002
    • (2008) Pain , vol.138 , pp. 41-46
    • Kamaleri, Y.1    Natvig, B.2    Ihlebaek, C.M.3    Bruusgaard, D.4
  • 2
    • 34250803204 scopus 로고    scopus 로고
    • Epidemiology of chronic musculoskeletal pain
    • DOI 10.1016/j.berh.2007.03.003, PII S152169420700037X, General Musculoskeletal Conditions
    • J McBeth K Jones 2007 Epidemiology of chronic musculoskeletal pain Best Pract Res Clin Rheumatol 21 403 425 17602991 10.1016/j.berh.2007.03.003 (Pubitemid 46972006)
    • (2007) Best Practice and Research in Clinical Rheumatology , vol.21 , Issue.3 , pp. 403-425
    • McBeth, J.1    Jones, K.2
  • 3
    • 33645802799 scopus 로고    scopus 로고
    • The epidemiology of chronic syndromes that are frequently unexplained: Do they have common associated factors?
    • 16303810 10.1093/ije/dyi265
    • VR Aggarwal J McBeth JM Zakrzewska, et al. 2006 The epidemiology of chronic syndromes that are frequently unexplained: do they have common associated factors? Int J Epidemiol 35 468 476 16303810 10.1093/ije/dyi265
    • (2006) Int J Epidemiol , vol.35 , pp. 468-476
    • Aggarwal, V.R.1    McBeth, J.2    Zakrzewska, J.M.3
  • 4
    • 34047101951 scopus 로고    scopus 로고
    • The role of psychosocial factors in predicting the onset of chronic widespread pain: Results from a prospective population-based study
    • DOI 10.1093/rheumatology/kel363
    • A Gupta AJ Silman D Ray, et al. 2007 The role of psychosocial factors in predicting the onset of chronic widespread pain: results from a prospective population-based study Rheumatol (Oxford) 46 666 671 10.1093/rheumatology/kel363 1:STN:280:DC%2BD2s7nvFSnsw%3D%3D (Pubitemid 46523314)
    • (2007) Rheumatology , vol.46 , Issue.4 , pp. 666-671
    • Gupta, A.1    Silman, A.J.2    Ray, D.3    Morriss, R.4    Dickens, C.5    MacFarlane, G.J.6    Chiu, Y.H.7    Nicholl, B.8    McBeth, J.9
  • 5
    • 63449108990 scopus 로고    scopus 로고
    • Adverse events in childhood and chronic widespread pain in adult life: Results from the 1958 British Birth Cohort Study
    • 19304391 10.1016/j.pain.2009.02.003
    • GT Jones C Power GJ Macfarlane 2009 Adverse events in childhood and chronic widespread pain in adult life: results from the 1958 British Birth Cohort Study Pain 143 92 96 19304391 10.1016/j.pain.2009.02.003
    • (2009) Pain , vol.143 , pp. 92-96
    • Jones, G.T.1    Power, C.2    MacFarlane, G.J.3
  • 6
    • 33646493363 scopus 로고    scopus 로고
    • Importance of genetic influences on chronic widespread pain
    • 16646040 10.1002/art.21798 1:CAS:528:DC%2BD28XlsFWjs70%3D
    • K Kato PF Sullivan B Evengard NL Pedersen 2006 Importance of genetic influences on chronic widespread pain Arthritis Rheum 54 1682 1686 16646040 10.1002/art.21798 1:CAS:528:DC%2BD28XlsFWjs70%3D
    • (2006) Arthritis Rheum , vol.54 , pp. 1682-1686
    • Kato, K.1    Sullivan, P.F.2    Evengard, B.3    Pedersen, N.L.4
  • 7
    • 1842780898 scopus 로고    scopus 로고
    • Structural, Psychological, and Genetic Influences on Low Back and Neck Pain: A Study of Adult Female Twins
    • AJ MacGregor T Andrew PN Sambrook TD Spector 2004 Structural, psychological, and genetic influences on low back and neck pain: a study of adult female twins Arthritis Rheum 51 160 167 15077255 10.1002/art.20236 (Pubitemid 38468697)
    • (2004) Arthritis Care and Research , vol.51 , Issue.2 , pp. 160-167
    • MacGregor, A.J.1    Andrew, T.2    Sambrook, P.N.3    Spector, T.D.4
  • 8
    • 70349759521 scopus 로고    scopus 로고
    • Heritability of spinal pain and consequences of spinal pain: A comprehensive genetic epidemiologic analysis using a population-based sample of 15,328 twins ages 20-71 years
    • 19790135 10.1002/art.24607
    • J Hartvigsen J Nielsen KO Kyvik, et al. 2009 Heritability of spinal pain and consequences of spinal pain: a comprehensive genetic epidemiologic analysis using a population-based sample of 15,328 twins ages 20-71 years Arthritis Rheum 61 1343 1351 19790135 10.1002/art.24607
    • (2009) Arthritis Rheum , vol.61 , pp. 1343-1351
    • Hartvigsen, J.1    Nielsen, J.2    Kyvik, K.O.3
  • 9
    • 0035089834 scopus 로고    scopus 로고
    • Widespread pain among 11-year-old Finnish twin pairs
    • DOI 10.1002/1529-0131(200102)44:2<481::AID-ANR68>3.0.CO;2-X
    • M Mikkelsson J Kaprio JJ Salminen, et al. 2001 Widespread pain among 11-year-old Finnish twin pairs Arthritis Rheum 44 481 485 11229481 10.1002/1529-0131(200102)44:2<481::AID-ANR68>3.0.CO;2-X 1:STN:280:DC%2BD3M7lvFSisg%3D%3D (Pubitemid 32207043)
    • (2001) Arthritis and Rheumatism , vol.44 , Issue.2 , pp. 481-485
    • Ihn, H.1    Yamane, K.2    Kubo, M.3    Tamaki, K.4
  • 10
    • 42149086601 scopus 로고    scopus 로고
    • Genetic and environmental influences on non-specific low back pain in children: A twin study
    • 18205017 10.1007/s00586-008-0605-1
    • A El-Metwally M Mikkelsson M Stahl, et al. 2008 Genetic and environmental influences on non-specific low back pain in children: a twin study Eur Spine J 17 502 508 18205017 10.1007/s00586-008-0605-1
    • (2008) Eur Spine J , vol.17 , pp. 502-508
    • El-Metwally, A.1    Mikkelsson, M.2    Stahl, M.3
  • 11
    • 1542514853 scopus 로고    scopus 로고
    • Heredity of Low Back Pain in a Young Population: A Classical Twin Study
    • DOI 10.1375/13690520460741408
    • L Hestbaek IA Iachine C Leboeuf-Yde, et al. 2004 Heredity of low back pain in a young population: a classical twin study Twin Res 7 16 26 15053850 10.1375/13690520460741408 (Pubitemid 38332542)
    • (2004) Twin Research , vol.7 , Issue.1 , pp. 16-26
    • Hestbaek, L.1    Iachine, I.A.2    Leboeuf-Yde, C.3    Kyvik, K.O.4    Manniche, C.5
  • 12
    • 33646184868 scopus 로고    scopus 로고
    • Heritability of neck pain: A population-based study of 33,794 Danish twins
    • 10.1093/rheumatology/kei224 1:STN:280:DC%2BD283itV2jtQ%3D%3D
    • R Fejer J Hartvigsen KO Kyvik 2006 Heritability of neck pain: a population-based study of 33,794 Danish twins Rheumatol (Oxford) 45 589 594 10.1093/rheumatology/kei224 1:STN:280:DC%2BD283itV2jtQ%3D%3D
    • (2006) Rheumatol (Oxford) , vol.45 , pp. 589-594
    • Fejer, R.1    Hartvigsen, J.2    Kyvik, K.O.3
  • 13
    • 58149215495 scopus 로고    scopus 로고
    • Change in the number of musculoskeletal pain sites: A 14-year prospective study
    • 18977088 10.1016/j.pain.2008.09.013
    • Y Kamaleri B Natvig CM Ihlebaek, et al. 2009 Change in the number of musculoskeletal pain sites: a 14-year prospective study Pain 141 25 30 18977088 10.1016/j.pain.2008.09.013
    • (2009) Pain , vol.141 , pp. 25-30
    • Kamaleri, Y.1    Natvig, B.2    Ihlebaek, C.M.3
  • 14
    • 77955764740 scopus 로고    scopus 로고
    • Pain reporting at different body sites is explained by a single underlying genetic factor
    • 10.1093/rheumatology/keq170 1:CAS:528:DC%2BC3cXhtVektbbE
    • FM Williams TD Spector AJ MacGregor 2010 Pain reporting at different body sites is explained by a single underlying genetic factor Rheumatol (Oxford) 49 1753 1755 10.1093/rheumatology/keq170 1:CAS:528:DC%2BC3cXhtVektbbE This twin study demonstrated that the heritability of self-reported pain is not influenced by site
    • (2010) Rheumatol (Oxford) , vol.49 , pp. 1753-1755
    • Williams, F.M.1    Spector, T.D.2    MacGregor, A.J.3
  • 15
    • 80053228155 scopus 로고    scopus 로고
    • High heritability for concurrent low back and neck-shoulder pain - A study of twins
    • E-pub
    • Nyman T, Mulder M, Iliadou A, et al. High heritability for concurrent low back and neck-shoulder pain-a study of twins. Spine (Phila Pa 1976). 2010, E-pub
    • (2010) Spine (Phila Pa 1976)
    • Nyman, T.1    Mulder, M.2    Iliadou, A.3
  • 16
    • 33745685822 scopus 로고    scopus 로고
    • Idiopathic pain disorders-pathways of vulnerability
    • 16777329 10.1016/j.pain.2006.04.015
    • L Diatchenko AG Nackley GD Slade, et al. 2006 Idiopathic pain disorders-pathways of vulnerability Pain 123 226 230 16777329 10.1016/j.pain.2006.04.015
    • (2006) Pain , vol.123 , pp. 226-230
    • Diatchenko, L.1    Nackley, A.G.2    Slade, G.D.3
  • 17
    • 66149166219 scopus 로고    scopus 로고
    • A population-based twin study of functional somatic syndromes
    • 18578896 10.1017/S0033291708003784
    • K Kato PF Sullivan B Evengard NL Pedersen 2008 A population-based twin study of functional somatic syndromes Psychol Med 39 497 505 18578896 10.1017/S0033291708003784 This twin study showed that there are likely to be affective and sensory genetic components to functional syndromes, as well as common and unique susceptibility genes for these syndromes
    • (2008) Psychol Med , vol.39 , pp. 497-505
    • Kato, K.1    Sullivan, P.F.2    Evengard, B.3    Pedersen, N.L.4
  • 18
    • 0036668017 scopus 로고    scopus 로고
    • Back-neck pain and symptoms of anxiety and depression: A population-based twin study
    • 12214782 10.1017/S0033291702005950 1:STN:280:DC%2BD38vls1Wmsw%3D%3D
    • T Reichborn-Kjennerud C Stoltenberg K Tambs, et al. 2002 Back-neck pain and symptoms of anxiety and depression: a population-based twin study Psychol Med 32 1009 1020 12214782 10.1017/S0033291702005950 1:STN:280: DC%2BD38vls1Wmsw%3D%3D
    • (2002) Psychol Med , vol.32 , pp. 1009-1020
    • Reichborn-Kjennerud, T.1    Stoltenberg, C.2    Tambs, K.3
  • 19
    • 42949112011 scopus 로고    scopus 로고
    • Exploring the genetic susceptibility of chronic widespread pain: The tender points in genetic association studies
    • DOI 10.1093/rheumatology/ken027
    • KL Limer BI Nicholl W Thomson J McBeth 2008 Exploring the genetic susceptibility of chronic widespread pain: the tender points in genetic association studies Rheumatol (Oxford) 47 572 577 10.1093/rheumatology/ken027 1:CAS:528:DC%2BD1cXkvFymt7w%3D (Pubitemid 351619192)
    • (2008) Rheumatology , vol.47 , Issue.5 , pp. 572-577
    • Limer, K.L.1    Nicholl, B.I.2    Thomson, W.3    Mcbeth, J.4
  • 22
    • 77349086822 scopus 로고    scopus 로고
    • Genetic variation in the beta2-adrenergic receptor but not catecholamine-O-methyltransferase predisposes to chronic pain: Results from the 1958 British Birth Cohort Study
    • 20167428 10.1016/j.pain.2010.01.023 1:CAS:528:DC%2BC3cXivFegsb4%3D
    • LJ Hocking BH Smith GT Jones, et al. 2010 Genetic variation in the beta2-adrenergic receptor but not catecholamine-O-methyltransferase predisposes to chronic pain: results from the 1958 British Birth Cohort Study Pain 149 143 151 20167428 10.1016/j.pain.2010.01.023 1:CAS:528:DC%2BC3cXivFegsb4%3D This was a large birth cohort study demonstrating an association between ADRB2 and the extent and chronification of pain
    • (2010) Pain , vol.149 , pp. 143-151
    • Hocking, L.J.1    Smith, B.H.2    Jones, G.T.3
  • 23
    • 78149489881 scopus 로고    scopus 로고
    • No evidence for a role of the catechol-O-methyltransferase (COMT) pain sensitivity haplotype in chronic widespread pain
    • 20570835 10.1136/ard.2009.126086
    • BI Nicholl KL Holliday GJ Macfarlane, et al. 2010 No evidence for a role of the catechol-O-methyltransferase (COMT) pain sensitivity haplotype in chronic widespread pain Ann Rheum Dis 69 2009 2012 20570835 10.1136/ard.2009.126086
    • (2010) Ann Rheum Dis , vol.69 , pp. 2009-2012
    • Nicholl, B.I.1    Holliday, K.L.2    MacFarlane, G.J.3
  • 24
    • 79958802470 scopus 로고    scopus 로고
    • Serotonin receptor (5-HT 2A) and catechol-O-methyltransferase (COMT) gene polymorphisms: Triggers of fibromyalgia?
    • 21125150 10.1590/S0482-50042010000200004
    • JB Matsuda FR Barbosa LJ Morel, et al. 2010 Serotonin receptor (5-HT 2A) and catechol-O-methyltransferase (COMT) gene polymorphisms: triggers of fibromyalgia? Rev Bras Reumatol 50 141 149 21125150 10.1590/S0482- 50042010000200004
    • (2010) Rev Bras Reumatol , vol.50 , pp. 141-149
    • Matsuda, J.B.1    Barbosa, F.R.2    Morel, L.J.3
  • 25
    • 59649093445 scopus 로고    scopus 로고
    • A functional polymorphism in the catechol-O-methyltransferase gene is associated with osteoarthritis-related pain
    • 19180497 10.1002/art.24175
    • JB van Meurs AG Uitterlinden L Stolk, et al. 2009 A functional polymorphism in the catechol-O-methyltransferase gene is associated with osteoarthritis-related pain Arthritis Rheum 60 628 629 19180497 10.1002/art.24175
    • (2009) Arthritis Rheum , vol.60 , pp. 628-629
    • Van Meurs, J.B.1    Uitterlinden, A.G.2    Stolk, L.3
  • 26
    • 77949632853 scopus 로고    scopus 로고
    • Genetic influences on the dynamics of pain and affect in fibromyalgia
    • 20230086 10.1037/a0018647
    • PH Finan AJ Zautra MC Davis, et al. 2010 Genetic influences on the dynamics of pain and affect in fibromyalgia Health Psychol 29 134 142 20230086 10.1037/a0018647
    • (2010) Health Psychol , vol.29 , pp. 134-142
    • Finan, P.H.1    Zautra, A.J.2    Davis, M.C.3
  • 27
    • 78149456950 scopus 로고    scopus 로고
    • The genetic influence on the cortical processing of experimental pain and the moderating effect of pain status
    • 21049025 10.1371/journal.pone.0013641
    • H Vossen G Kenis B Rutten, et al. 2010 The genetic influence on the cortical processing of experimental pain and the moderating effect of pain status PLoS One 5 e13641 21049025 10.1371/journal.pone.0013641
    • (2010) PLoS One , vol.5 , pp. 13641
    • Vossen, H.1    Kenis, G.2    Rutten, B.3
  • 29
    • 67650069658 scopus 로고    scopus 로고
    • Association of adrenergic receptor gene polymorphisms with different fibromyalgia syndrome domains
    • 19565482 10.1002/art.24655 1:CAS:528:DC%2BD1MXptlKrsLg%3D
    • G Vargas-Alarcon JM Fragoso D Cruz-Robles, et al. 2009 Association of adrenergic receptor gene polymorphisms with different fibromyalgia syndrome domains Arthritis Rheum 60 2169 2173 19565482 10.1002/art.24655 1:CAS:528:DC%2BD1MXptlKrsLg%3D
    • (2009) Arthritis Rheum , vol.60 , pp. 2169-2173
    • Vargas-Alarcon, G.1    Fragoso, J.M.2    Cruz-Robles, D.3
  • 30
    • 70350620288 scopus 로고    scopus 로고
    • Meta-analysis of the relevance of the OPRM1 118A>G genetic variant for pain treatment
    • 19683391 10.1016/j.pain.2009.07.013 1:CAS:528:DC%2BD1MXhtlygs7fM
    • C Walter J Lotsch 2009 Meta-analysis of the relevance of the OPRM1 118A>G genetic variant for pain treatment Pain 146 270 275 19683391 10.1016/j.pain.2009.07.013 1:CAS:528:DC%2BD1MXhtlygs7fM
    • (2009) Pain , vol.146 , pp. 270-275
    • Walter, C.1    Lotsch, J.2
  • 31
    • 61849086376 scopus 로고    scopus 로고
    • Expansion of the human mu-opioid receptor gene architecture: Novel functional variants
    • 19103668 10.1093/hmg/ddn439 1:CAS:528:DC%2BD1MXisFSmt7s%3D
    • SA Shabalina DV Zaykin P Gris, et al. 2009 Expansion of the human mu-opioid receptor gene architecture: novel functional variants Hum Mol Genet 18 1037 1051 19103668 10.1093/hmg/ddn439 1:CAS:528:DC%2BD1MXisFSmt7s%3D
    • (2009) Hum Mol Genet , vol.18 , pp. 1037-1051
    • Shabalina, S.A.1    Zaykin, D.V.2    Gris, P.3
  • 32
    • 75349090421 scopus 로고    scopus 로고
    • Do genetic predictors of pain sensitivity associate with persistent widespread pain?
    • 19775452 10.1186/1744-8069-5-56
    • KL Holliday BI Nicholl GJ Macfarlane, et al. 2009 Do genetic predictors of pain sensitivity associate with persistent widespread pain? Mol Pain 5 56 19775452 10.1186/1744-8069-5-56
    • (2009) Mol Pain , vol.5 , pp. 56
    • Holliday, K.L.1    Nicholl, B.I.2    MacFarlane, G.J.3
  • 34
    • 36849036949 scopus 로고    scopus 로고
    • Mutations in sodium-channel gene SCN9A cause a spectrum of human genetic pain disorders
    • DOI 10.1172/JCI33297
    • JP Drenth SG Waxman 2007 Mutations in sodium-channel gene SCN9A cause a spectrum of human genetic pain disorders J Clin Investig 117 3603 3609 18060017 10.1172/JCI33297 1:CAS:528:DC%2BD2sXhsVals7bP (Pubitemid 350224065)
    • (2007) Journal of Clinical Investigation , vol.117 , Issue.12 , pp. 3603-3609
    • Drenth, J.P.H.1    Waxman, S.G.2
  • 35
    • 77950429077 scopus 로고    scopus 로고
    • Pain perception is altered by a nucleotide polymorphism in SCN9A
    • 20212137 10.1073/pnas.0913181107 1:CAS:528:DC%2BC3cXjvFaqur0%3D
    • F Reimann JJ Cox I Belfer, et al. 2010 Pain perception is altered by a nucleotide polymorphism in SCN9A Proc Natl Acad Sci U S A 107 5148 5153 20212137 10.1073/pnas.0913181107 1:CAS:528:DC%2BC3cXjvFaqur0%3D This study identified a common nonsynonymous polymorphism associated with pain intensity in multiple pain phenotypes in an ion channel gene, SCN9A, in which mutations have caused severe pain disorders and congenital insensitivity to pain
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 5148-5153
    • Reimann, F.1    Cox, J.J.2    Belfer, I.3
  • 36
    • 73549101494 scopus 로고    scopus 로고
    • A sodium channel gene SCN9A polymorphism that increases nociceptor excitability
    • 20033988 10.1002/ana.21895 1:CAS:528:DC%2BC3cXhtlamsLY%3D
    • M Estacion TP Harty JS Choi, et al. 2009 A sodium channel gene SCN9A polymorphism that increases nociceptor excitability Ann Neurol 66 862 866 20033988 10.1002/ana.21895 1:CAS:528:DC%2BC3cXhtlamsLY%3D
    • (2009) Ann Neurol , vol.66 , pp. 862-866
    • Estacion, M.1    Harty, T.P.2    Choi, J.S.3
  • 37
    • 80755137515 scopus 로고    scopus 로고
    • Role of the Na(V)1.7 R1150W amino acid change in susceptibility to symptomatic knee osteoarthritis and multiple regional pain
    • Valdes AM, Arden NK, Vaughn FL, et al. Role of the Na(V)1.7 R1150W amino acid change in susceptibility to symptomatic knee osteoarthritis and multiple regional pain. Arthritis Care Res. (Hoboken). 2010
    • (2010) Arthritis Care Res. (Hoboken)
    • Valdes, A.M.1    Arden, N.K.2    Vaughn, F.L.3
  • 38
    • 78049443982 scopus 로고    scopus 로고
    • Pain as a channelopathy
    • 21041956 10.1172/JCI43158 1:CAS:528:DC%2BC3cXhsVWgtb3N
    • R Raouf K Quick JN Wood 2010 Pain as a channelopathy J Clin Investig 120 3745 3752 21041956 10.1172/JCI43158 1:CAS:528:DC%2BC3cXhsVWgtb3N
    • (2010) J Clin Investig , vol.120 , pp. 3745-3752
    • Raouf, R.1    Quick, K.2    Wood, J.N.3
  • 39
    • 77956390028 scopus 로고    scopus 로고
    • Multiple chronic pain states are associated with a common amino acid-changing allele in KCNS1
    • 20724292 10.1093/brain/awq195
    • M Costigan I Belfer RS Griffin, et al. 2010 Multiple chronic pain states are associated with a common amino acid-changing allele in KCNS1 Brain 133 2519 2527 20724292 10.1093/brain/awq195
    • (2010) Brain , vol.133 , pp. 2519-2527
    • Costigan, M.1    Belfer, I.2    Griffin, R.S.3
  • 40
    • 78149472321 scopus 로고    scopus 로고
    • A genome-wide drosophila screen for heat nociception identifies alpha2delta3 as an evolutionarily conserved pain gene
    • 21074052 10.1016/j.cell.2010.09.047 1:CAS:528:DC%2BC3cXhsVahtbvK
    • GG Neely A Hess M Costigan, et al. 2010 A genome-wide drosophila screen for heat nociception identifies alpha2delta3 as an evolutionarily conserved pain gene Cell 143 628 638 21074052 10.1016/j.cell.2010.09.047 1:CAS:528: DC%2BC3cXhsVahtbvK
    • (2010) Cell , vol.143 , pp. 628-638
    • Neely, G.G.1    Hess, A.2    Costigan, M.3
  • 41
    • 2942566415 scopus 로고    scopus 로고
    • Psychological stress and fibromyalgia: A review of the evidence suggesting a neuroendocrine link
    • A Gupta AJ Silman 2004 Psychological stress and fibromyalgia: a review of the evidence suggesting a neuroendocrine link Arthritis Res Ther 6 98 106 15142258 10.1186/ar1176 1:CAS:528:DC%2BD2cXot1Wlsro%3D (Pubitemid 38735664)
    • (2004) Arthritis Research and Therapy , vol.6 , Issue.3 , pp. 98-106
    • Gupta, A.1    Silman, A.J.2
  • 42
    • 79953678962 scopus 로고    scopus 로고
    • HTR2A polymorphisms are associated with chronic widespread pain and the extent of musculoskeletal pain: Results from two population-based cohorts
    • 21305503 10.1002/art.30185 1:CAS:528:DC%2BC3MXksFWrs7Y%3D
    • BI Nicholl KL Holliday GJ Macfarlane, et al. 2011 HTR2A polymorphisms are associated with chronic widespread pain and the extent of musculoskeletal pain: results from two population-based cohorts Arthritis Rheum 63 810 818 21305503 10.1002/art.30185 1:CAS:528:DC%2BC3MXksFWrs7Y%3D This was a two-stage genetic study implicating a region in the serotonin receptor 2A gene as important in susceptibility to CWP and the extent of pain reporting
    • (2011) Arthritis Rheum , vol.63 , pp. 810-818
    • Nicholl, B.I.1    Holliday, K.L.2    MacFarlane, G.J.3
  • 44
    • 77955553364 scopus 로고    scopus 로고
    • No relationship between the ins del polymorphism of the serotonin transporter promoter and pain perception in fibromyalgia patients and healthy controls
    • 20080425 10.1016/j.ejpain.2009.12.004 1:CAS:528:DC%2BC3cXovFeltbg%3D
    • S Potvin A Larouche E Normand, et al. 2010 No relationship between the ins del polymorphism of the serotonin transporter promoter and pain perception in fibromyalgia patients and healthy controls Eur J Pain 14 742 746 20080425 10.1016/j.ejpain.2009.12.004 1:CAS:528:DC%2BC3cXovFeltbg%3D
    • (2010) Eur J Pain , vol.14 , pp. 742-746
    • Potvin, S.1    Larouche, A.2    Normand, E.3
  • 45
    • 79952659840 scopus 로고    scopus 로고
    • Perception of thermal pain and the thermal grill illusion is associated with polymorphisms in the serotonin transporter gene
    • 21423614 10.1371/journal.pone.0017752 1:CAS:528:DC%2BC3MXktVWjsbo%3D
    • F Lindstedt TB Lonsdorf M Schalling, et al. 2011 Perception of thermal pain and the thermal grill illusion is associated with polymorphisms in the serotonin transporter gene PLoS One 6 e17752 21423614 10.1371/journal.pone. 0017752 1:CAS:528:DC%2BC3MXktVWjsbo%3D
    • (2011) PLoS One , vol.6 , pp. 17752
    • Lindstedt, F.1    Lonsdorf, T.B.2    Schalling, M.3
  • 46
    • 79953134062 scopus 로고    scopus 로고
    • Conditioned pain modulation is associated with common polymorphisms in the serotonin transporter gene
    • 21464942 10.1371/journal.pone.0018252 1:CAS:528:DC%2BC3MXksFCgtL8%3D
    • F Lindstedt J Berrebi E Greayer, et al. 2011 Conditioned pain modulation is associated with common polymorphisms in the serotonin transporter gene PLoS One 6 e18252 21464942 10.1371/journal.pone.0018252 1:CAS:528: DC%2BC3MXksFCgtL8%3D
    • (2011) PLoS One , vol.6 , pp. 18252
    • Lindstedt, F.1    Berrebi, J.2    Greayer, E.3
  • 47
    • 33846238504 scopus 로고    scopus 로고
    • Moderation of psychosocial risk factors through dysfunction of the hypothalamic-pituitary-adrenal stress axis in the onset of chronic widespread musculoskeletal pain: Findings of a population-based prospective cohort study
    • DOI 10.1002/art.22336
    • J McBeth AJ Silman A Gupta, et al. 2007 Moderation of psychosocial risk factors through dysfunction of the hypothalamic-pituitary-adrenal stress axis in the onset of chronic widespread musculoskeletal pain: findings of a population-based prospective cohort study Arthritis Rheum 56 360 371 17195240 10.1002/art.22336 1:STN:280:DC%2BD2s%2FltlWhuw%3D%3D (Pubitemid 46106210)
    • (2007) Arthritis and Rheumatism , vol.56 , Issue.1 , pp. 360-371
    • McBeth, J.1    Silman, A.J.2    Gupta, A.3    Chiu, Y.H.4    Ray, D.5    Morriss, R.6    Dickens, C.7    King, Y.8    Macfarlane, G.J.9
  • 48
    • 77949450904 scopus 로고    scopus 로고
    • Genetic variation in the hypothalamic-pituitary-adrenal stress axis influences susceptibility to musculoskeletal pain: Results from the EPIFUND study
    • 19723618 10.1136/ard.2009.116137
    • KL Holliday BI Nicholl GJ Macfarlane, et al. 2010 Genetic variation in the hypothalamic-pituitary-adrenal stress axis influences susceptibility to musculoskeletal pain: results from the EPIFUND study Ann Rheum Dis 69 556 560 19723618 10.1136/ard.2009.116137
    • (2010) Ann Rheum Dis , vol.69 , pp. 556-560
    • Holliday, K.L.1    Nicholl, B.I.2    MacFarlane, G.J.3
  • 49
    • 77953824896 scopus 로고    scopus 로고
    • Genetic variation in neuroendocrine genes associates with somatic symptoms in the general population: Results from the EPIFUND study
    • 20403506 10.1016/j.jpsychores.2010.01.024
    • KL Holliday GJ Macfarlane BI Nicholl, et al. 2010 Genetic variation in neuroendocrine genes associates with somatic symptoms in the general population: results from the EPIFUND study J Psychosom Res 68 469 474 20403506 10.1016/j.jpsychores.2010.01.024 This was a population-based study implicating neuroendocrine mechanisms in the genetic susceptibility of reporting somatic symptoms
    • (2010) J Psychosom Res , vol.68 , pp. 469-474
    • Holliday, K.L.1    MacFarlane, G.J.2    Nicholl, B.I.3
  • 50
    • 67249117049 scopus 로고    scopus 로고
    • Potential etiologic and functional implications of genome-wide association loci for human diseases and traits
    • 19474294 10.1073/pnas.0903103106 1:CAS:528:DC%2BD1MXot1Cgur4%3D
    • LA Hindorff P Sethupathy HA Junkins, et al. 2009 Potential etiologic and functional implications of genome-wide association loci for human diseases and traits Proc Natl Acad Sci U S A 106 9362 9367 19474294 10.1073/pnas.0903103106 1:CAS:528:DC%2BD1MXot1Cgur4%3D
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 9362-9367
    • Hindorff, L.A.1    Sethupathy, P.2    Junkins, H.A.3


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