Moderation of psychosocial risk factors through dysfunction of the hypothalamic-pituitary-adrenal stress axis in the onset of chronic widespread musculoskeletal pain: Findings of a population-based prospective cohort study

Arthritis and Rheumatism

Volumn 56, Issue 1, 2007, Pages 360-371

  McBeth, J ^a   Silman, A J ^a   Gupta, A ^a   Chiu, Y H ^a   Ray, D ^a   Morriss, R ^b   Dickens, C ^a   King, Y ^a   Macfarlane, G J ^a,c  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b ROYAL LIVERPOOL UNIVERSITY HOSPITAL   (United Kingdom)

^c UNIVERSITY OF ABERDEEN   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DEXAMETHASONE; HYDROCORTISONE;

ADULT; ANXIETY DISORDER; ARTICLE; ATTITUDE TO ILLNESS; CHRONIC PAIN; CHRONIC WIDESPREAD PAIN; DEPRESSION; DISEASE PREDISPOSITION; FEMALE; GENERAL HEALTH QUESTIONNAIRE; HORMONE DETERMINATION; HOSPITAL ANXIETY AND DEPRESSION SCALE; HUMAN; HYDROCORTISONE BLOOD LEVEL; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; ILLNESS ATTITUDE SCALE; IMMUNOASSAY; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MALE; PAIN; PATIENT ATTITUDE; PREDICTION; PRIORITY JOURNAL; PSYCHOLOGICAL ASPECT; QUESTIONNAIRE; RATING SCALE; RISK FACTOR; SALIVA LEVEL; SLEEP DISORDER; SLEEP PROBLEM SCALE; SOCIAL ASPECT; STRESS;

ADULT; AGED; CHRONIC DISEASE; COHORT STUDIES; FEMALE; GREAT BRITAIN; HUMANS; HYDROCORTISONE; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; MALE; MIDDLE AGED; MUSCULOSKELETAL DISEASES; ODDS RATIO; PAIN; PAIN MEASUREMENT; PITUITARY-ADRENAL SYSTEM; PROSPECTIVE STUDIES; RISK FACTORS; STRESS, PSYCHOLOGICAL;

EID: 33846238504     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.22336     Document Type: Article

References (32)

1. Croft PR, Rigby AS, Boswell R, Schollum J, Silman AJ. The prevalence of chronic widespread pain in the general population. J Rheumatol 1993;20:710-3.
2. Macfarlane GJ, McBeth J, Silman AJ. Widespread body pain and mortality: prospective population based study. Br Med J 2001;323:662-5.
3. McBeth J, Macfarlane GJ, Benjamin S, Silman AJ. Features of somatization predict the onset of chronic widespread pain: results of a large population-based study. Arthritis Rheum 2001;44:940-6.
4. Gupta A, Silman AJ. Psychological stress and fibromyalgia: a review of the evidence suggesting a neuroendocrine link. Arthritis Res Ther 2004;6:98-106.
5. Crofford LJ, Pillemer SR, Kalogeras KT, Cash JM, Michelson D, Kling MA, et al. Hypothalamic-pituitary-adrenal axis perturbations in patients with fibromyalgia. Arthritis Rheum 1994;37:1583-92.
6. Griep EN, Boersma JW, Lentjes EG, Prins AP, Van der Korst JK, de Kloet ER. Function of the hypothalamic-pituitary-adrenal axis in patients with fibromyalgia and low back pain. J Rheumatol 1998;25:1374-81.
7. Griep EN, Boersma JW, de Kloet ER. Altered reactivity of the hypothalamic-pituitary-adrenal axis in the primary fibromyalgia syndrome. J Rheumatol 1993;20:469-74.
8. Wolfe F, Smythe HA, Yunus MB, Bennett RM, Bombardier C, Goldenberg DL, et al. The American College of Rheumatology 1990 criteria for the classification of fibromyalgia: report of the Multicenter Criteria Committee. Arthritis Rheum 1990;33:160-72.
9. McBeth J, Chiu YH, Silman AJ, Ray D, Morriss R, Dickens C, et al. Hypothalamic-pituitary-adrenal stress axis function and the relationship with chronic widespread pain and its antecedents. Arthritis Res Ther 2005;7:R992-1000.
10. Goldberg DP, Williams P. Users' guide to the General Health Questionnaire. Windsor (UK): Nfer-Nelson; 1988.
11. Kellner R, Hernandez J, Pathak D. Hypochondriacal fear and beliefs, anxiety, and somatisation. Br J Psychiatry 1992;160:525-32.
12. Speckens AE, Spinhoven P, Sloekers PP, Bolk JH, van Hemert AM. A validation study of the Whitely Index, the Illness Attitude Scales, and the Somatosensory Amplification Scale in general medical and general practice patients. J Psychosom Res 1996;40:95-104.
13. Zigmond AS, Snaith RP. The Hospital Anxiety and Depression Scale. Acta Psychiatr Scand 1983;67:361-70.
14. Jenkins CD, Stanton BA, Niemcryk SJ, Rose RM. A scale for the estimation of sleep problems in clinical research. J Clin Epidemiol 1988;41:313-21.
15. Brugha T, Bebbington P, Tennant C, Hurry J. The List of Threatening Experiences: a subset of 12 life event categories with considerable long-term contextual threat. Psychol Med 1985;15:189-94.
16. Van Rossum EF, Koper JW, van den Beld AW, Uitterlinden AG, Arp P, Ester W, et al. Identification of the BclI polymorphism in the glucocorticoid receptor gene: association with sensitivity to glucocorticoids in vivo and body mass index. Clin Endocrinol (Oxf) 2003;59:585-92.
17. Stevens A, Ray DW, Zeggini E, John S, Richards HL, Griffiths CE, et al. Glucocorticoid sensitivity is determined by a specific glucocorticoid receptor haplotype. J Clin Endocrinol Metab 2004;89:892-7.
18. Neeck G. Neuroendocrine and hormonal perturbations and relations to the serotonergic system in fibromyalgia patients. Scand J Rheumatol Suppl 2000;113:8-12.
19. Henry JL. Concepts of pain sensation and its modulation. J Rheumatol 1989;16:104-12.
20. Crofford LJ. The hypothalamic-pituitary-adrenal stress axis in fibromyalgia and chronic fatigue syndrome. Z Rheumatol 1998;57:67-71.
21. Hudson JI, Pliner LF, Hudson MS, Goldenberg DL, Melby JC. The dexamethasone suppression test in fibrositis. Biol Psychiatry 1984;19:1489-93.
22. Ferraccioli G, Cavalieri F, Salaffi F, Fontana S, Scita F, Nolli M, et al. Neuroendocrinologic findings in primary fibromyalgia (soft tissue chronic pain syndrome) and in other chronic rheumatic conditions (rheumatoid arthritis, low back pain). J Rheumatol 1990;17:869-73.
23. McCain GA, Tilbe KS. Diurnal hormone variation in fibromyalgia syndrome: a comparison with rheumatoid arthritis. J Rheumatol 1989;16 Suppl 19:154-7.
24. Crofford LJ, Young EA, Engleberg NC, Korszun A, Brucksch CB, McClure LA, et al. Basal circadian and pulsatile ACTH and cortisol secretion in patients with fibromyalgia and/or chronic fatigue syndrome. Brain Behav Immun 2004;18:314-25.
25. Van Voorhees E, Scarpa A. The effects of child maltreatment on the hypothalamic-pituitary-adrenal axis. Trauma Violence Abuse 2004;5:333-52.
26. Nicolson NA. Childhood parental loss and cortisol levels in adult men. Psychoneuroendocrinology 2004;29:1012-8.
27. Wust S, Entringer S, Federenko IS, Schlotz W, Hellhammer DH. Birth weight is associated with salivary cortisol responses to psychosocial stress in adult life. Psychoneuroendocrinology 2005;30:591-8.
28. Offenbaecher M, Bondy B, de Jonge S, Glatzeder K, Kruger M, Schoeps P, et al. Possible association of fibromyalgia with a polymorphism in the serotonin transporter gene regulatory region. Arthritis Rheum 1999;42:2482-8.
29. Gursoy S. Absence of association of the serotonin transporter gene polymorphism with the mentally healthy subset of fibromyalgia patients. Clin Rheumatol 2002;21:194-7.
30. Gursoy S, Erdal E, Herken H, Madenci E, Alasehirli B. Association of T102C polymorphism of the 5-HT2A receptor gene with psychiatric status in fibromyalgia syndrome. Rheumatol Int 2001;21:58-61.
31. Russell IJ, Orr MD, Littman B, Vipraio GA, Alboukrek D, Michalek JE, et al. Elevated cerebrospinal fluid levels of Substance P in patients with the fibromyalgia syndrome. Arthritis Rheum 1994;37:37:1593-601.
32. Aggarwal VR, McBeth J, Zakrzewska JM, Lunt M, Macfarlane GJ. The epidemiology of chronic syndromes that are frequently unexplained: do they have common associated factors? Int J Epidemiol 2006;35:468-76.