메뉴 건너뛰기




Volumn 37, Issue 3, 2011, Pages 209-216

Electrophile-modified lipoic derivatives of PDC-E2 elicits anti-mitochondrial antibody reactivity

Author keywords

Anti mitochondrial antibodies; Primary biliary cirrhosis; Pyruvate dehydrogenase; Xenobiotics

Indexed keywords

2 OCTYNOIC ACID; 6,8 BIS(ACETYLTHIO)OCTANOIC ACID; DISULFIDE; ELECTROPHILE; IMMUNOGLOBULIN G; MITOCHONDRION ANTIBODY; OCTANOIC ACID; PYRUVATE DEHYDROGENASE COMPLEX; THIOCTIC ACID; UNCLASSIFIED DRUG; XENOBIOTIC AGENT;

EID: 80755133531     PISSN: 08968411     EISSN: 10959157     Source Type: Journal    
DOI: 10.1016/j.jaut.2011.06.001     Document Type: Article
Times cited : (40)

References (43)
  • 1
    • 77649179578 scopus 로고    scopus 로고
    • Geoepidemiology of autoimmune liver diseases
    • Invernizzi P. Geoepidemiology of autoimmune liver diseases. J Autoimmun 2010, 34:J300-J306.
    • (2010) J Autoimmun , vol.34
    • Invernizzi, P.1
  • 2
    • 39549115685 scopus 로고    scopus 로고
    • The causes of primary biliary cirrhosis: convenient and inconvenient truths
    • Gershwin M.E., Mackay I.R. The causes of primary biliary cirrhosis: convenient and inconvenient truths. Hepatology 2008, 47:737-745.
    • (2008) Hepatology , vol.47 , pp. 737-745
    • Gershwin, M.E.1    Mackay, I.R.2
  • 4
    • 34247633493 scopus 로고    scopus 로고
    • The X and why of xenobiotics in primary biliary cirrhosis
    • Rieger R., Gershwin M.E. The X and why of xenobiotics in primary biliary cirrhosis. J Autoimmun 2007, 28:76-84.
    • (2007) J Autoimmun , vol.28 , pp. 76-84
    • Rieger, R.1    Gershwin, M.E.2
  • 5
    • 75149196666 scopus 로고    scopus 로고
    • Immune tolerance: what is unique about the liver
    • Tiegs G., Lohse A.W. Immune tolerance: what is unique about the liver. J Autoimmun 2010, 34:1-6.
    • (2010) J Autoimmun , vol.34 , pp. 1-6
    • Tiegs, G.1    Lohse, A.W.2
  • 6
    • 75149129437 scopus 로고    scopus 로고
    • CD4 T cells in hepatic immune tolerance
    • Carambia A., Herkel J. CD4 T cells in hepatic immune tolerance. J Autoimmun 2010, 34:23-28.
    • (2010) J Autoimmun , vol.34 , pp. 23-28
    • Carambia, A.1    Herkel, J.2
  • 7
    • 75149177988 scopus 로고    scopus 로고
    • Viral triggers for autoimmunity: is the 'glass of molecular mimicry' half full or half empty?
    • Christen U., Hintermann E., Holdener M., von Herrath M.G. Viral triggers for autoimmunity: is the 'glass of molecular mimicry' half full or half empty?. J Autoimmun 2010, 34:38-44.
    • (2010) J Autoimmun , vol.34 , pp. 38-44
    • Christen, U.1    Hintermann, E.2    Holdener, M.3    von Herrath, M.G.4
  • 8
    • 77649185148 scopus 로고    scopus 로고
    • Defining and analyzing geoepidemiology and human autoimmunity
    • Shapira Y., Agmon-Levin N., Shoenfeld Y. Defining and analyzing geoepidemiology and human autoimmunity. J Autoimmun 2010, 34:J168-J177.
    • (2010) J Autoimmun , vol.34
    • Shapira, Y.1    Agmon-Levin, N.2    Shoenfeld, Y.3
  • 9
    • 70350072273 scopus 로고    scopus 로고
    • Are transient environmental agents involved in the cause of primary biliary cirrhosis? Evidence from space-time clustering analysis
    • McNally R.J., Ducker S., James O.F. Are transient environmental agents involved in the cause of primary biliary cirrhosis? Evidence from space-time clustering analysis. Hepatology 2009, 50:1169-1174.
    • (2009) Hepatology , vol.50 , pp. 1169-1174
    • McNally, R.J.1    Ducker, S.2    James, O.F.3
  • 10
    • 20944443874 scopus 로고    scopus 로고
    • Chemical xenobiotics and mitochondrial autoantigens in primary biliary cirrhosis: identification of antibodies against a common environmental, cosmetic, and food additive, 2-octynoic acid
    • Amano K., Leung P.S., Rieger R., Quan C., Wang X., Marik J., et al. Chemical xenobiotics and mitochondrial autoantigens in primary biliary cirrhosis: identification of antibodies against a common environmental, cosmetic, and food additive, 2-octynoic acid. J Immunol 2005, 174:5874-5883.
    • (2005) J Immunol , vol.174 , pp. 5874-5883
    • Amano, K.1    Leung, P.S.2    Rieger, R.3    Quan, C.4    Wang, X.5    Marik, J.6
  • 11
    • 33747763332 scopus 로고    scopus 로고
    • Identification of 2-nonynoic acid, a cosmetic component, as a potential trigger of primary biliary cirrhosis
    • Rieger R., Leung P.S., Jeddeloh M.R., Kurth M.J., Nantz M.H., Lam K.S., et al. Identification of 2-nonynoic acid, a cosmetic component, as a potential trigger of primary biliary cirrhosis. J Autoimmun 2006, 27:7-16.
    • (2006) J Autoimmun , vol.27 , pp. 7-16
    • Rieger, R.1    Leung, P.S.2    Jeddeloh, M.R.3    Kurth, M.J.4    Nantz, M.H.5    Lam, K.S.6
  • 12
    • 59249094523 scopus 로고    scopus 로고
    • Induction of autoimmune cholangitis in non-obese diabetic (NOD).1101 mice following a chemical xenobiotic immunization
    • Wakabayashi K., Yoshida K., Leung P.S., Moritoki Y., Yang G.X., Tsuneyama K., et al. Induction of autoimmune cholangitis in non-obese diabetic (NOD).1101 mice following a chemical xenobiotic immunization. Clin Exp Immunol 2009, 155:577-586.
    • (2009) Clin Exp Immunol , vol.155 , pp. 577-586
    • Wakabayashi, K.1    Yoshida, K.2    Leung, P.S.3    Moritoki, Y.4    Yang, G.X.5    Tsuneyama, K.6
  • 13
    • 49649091998 scopus 로고    scopus 로고
    • Loss of tolerance in C57BL/6 mice to the autoantigen E2 subunit of pyruvate dehydrogenase by a xenobiotic with ensuing biliary ductular disease
    • Wakabayashi K., Lian Z.X., Leung P.S., Moritoki Y., Tsuneyama K., Kurth M.J., et al. Loss of tolerance in C57BL/6 mice to the autoantigen E2 subunit of pyruvate dehydrogenase by a xenobiotic with ensuing biliary ductular disease. Hepatology 2008, 48:531-540.
    • (2008) Hepatology , vol.48 , pp. 531-540
    • Wakabayashi, K.1    Lian, Z.X.2    Leung, P.S.3    Moritoki, Y.4    Tsuneyama, K.5    Kurth, M.J.6
  • 14
    • 34848883199 scopus 로고    scopus 로고
    • Induction of primary biliary cirrhosis in guinea pigs following chemical xenobiotic immunization
    • Leung P.S., Park O., Tsuneyama K., Kurth M.J., Lam K.S., Ansari A.A., et al. Induction of primary biliary cirrhosis in guinea pigs following chemical xenobiotic immunization. J Immunol 2007, 179:2651-2657.
    • (2007) J Immunol , vol.179 , pp. 2651-2657
    • Leung, P.S.1    Park, O.2    Tsuneyama, K.3    Kurth, M.J.4    Lam, K.S.5    Ansari, A.A.6
  • 15
    • 25144474552 scopus 로고    scopus 로고
    • Primary biliary cirrhosis
    • Kaplan M.M., Gershwin M.E. Primary biliary cirrhosis. N Engl J Med 2005, 353:1261-1273.
    • (2005) N Engl J Med , vol.353 , pp. 1261-1273
    • Kaplan, M.M.1    Gershwin, M.E.2
  • 16
    • 0242490278 scopus 로고    scopus 로고
    • Incidence, clinical spectrum, and outcomes of primary sclerosing cholangitis in a United States community
    • Bambha K., Kim W.R., Talwalkar J., Torgerson H., Benson J.T., Therneau T.M., et al. Incidence, clinical spectrum, and outcomes of primary sclerosing cholangitis in a United States community. Gastroenterology 2003, 125:1364-1369.
    • (2003) Gastroenterology , vol.125 , pp. 1364-1369
    • Bambha, K.1    Kim, W.R.2    Talwalkar, J.3    Torgerson, H.4    Benson, J.T.5    Therneau, T.M.6
  • 18
    • 0031229830 scopus 로고    scopus 로고
    • Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus
    • Hochberg M.C. Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1997, 40:1725.
    • (1997) Arthritis Rheum , vol.40 , pp. 1725
    • Hochberg, M.C.1
  • 19
    • 0038559882 scopus 로고    scopus 로고
    • Immunization with a xenobiotic 6-bromohexanoate bovine serum albumin conjugate induces antimitochondrial antibodies
    • Leung P.S., Quan C., Park O., Van de Water J., Kurth M.J., Nantz M.H., et al. Immunization with a xenobiotic 6-bromohexanoate bovine serum albumin conjugate induces antimitochondrial antibodies. J Immunol 2003, 170:5326-5332.
    • (2003) J Immunol , vol.170 , pp. 5326-5332
    • Leung, P.S.1    Quan, C.2    Park, O.3    Van de Water, J.4    Kurth, M.J.5    Nantz, M.H.6
  • 20
    • 2442473106 scopus 로고    scopus 로고
    • Xenobiotic-induced loss of tolerance in rabbits to the mitochondrial autoantigen of primary biliary cirrhosis is reversible
    • Amano K., Leung P.S., Xu Q., Marik J., Quan C., Kurth M.J., et al. Xenobiotic-induced loss of tolerance in rabbits to the mitochondrial autoantigen of primary biliary cirrhosis is reversible. J Immunol 2004, 172:6444-6452.
    • (2004) J Immunol , vol.172 , pp. 6444-6452
    • Amano, K.1    Leung, P.S.2    Xu, Q.3    Marik, J.4    Quan, C.5    Kurth, M.J.6
  • 21
    • 4043079300 scopus 로고    scopus 로고
    • A novel approach to chemical microarray using ketone-modified macromolecular scaffolds: application in micro cell-adhesion assay
    • Xu Q., Miyamoto S., Lam K.S. A novel approach to chemical microarray using ketone-modified macromolecular scaffolds: application in micro cell-adhesion assay. Mol Divers 2004, 8:301-310.
    • (2004) Mol Divers , vol.8 , pp. 301-310
    • Xu, Q.1    Miyamoto, S.2    Lam, K.S.3
  • 22
    • 0034703453 scopus 로고    scopus 로고
    • Bromide-free TEMPO-mediated oxidation of primary alcohol groups in starch and methyl alpha-D-glucopyranoside
    • Bragd P.L., Besemer A.C., van Bekkum H. Bromide-free TEMPO-mediated oxidation of primary alcohol groups in starch and methyl alpha-D-glucopyranoside. Carbohydr Res 2000, 328:355-363.
    • (2000) Carbohydr Res , vol.328 , pp. 355-363
    • Bragd, P.L.1    Besemer, A.C.2    van Bekkum, H.3
  • 24
    • 0032401970 scopus 로고    scopus 로고
    • Chemoselective ligation reactions with proteins, oligosaccharides and cells
    • Lemieux G.A., Bertozzi C.R. Chemoselective ligation reactions with proteins, oligosaccharides and cells. Trends Biotechnol 1998, 16:506-513.
    • (1998) Trends Biotechnol , vol.16 , pp. 506-513
    • Lemieux, G.A.1    Bertozzi, C.R.2
  • 25
    • 0028960723 scopus 로고
    • Unprotected peptides as building blocks for the synthesis of peptide dendrimers with oxime, hydrazone, and thiazolidine linkages
    • Shao J., Tam J.P. Unprotected peptides as building blocks for the synthesis of peptide dendrimers with oxime, hydrazone, and thiazolidine linkages. J Am Chem Soc 1995, 117:3893-3899.
    • (1995) J Am Chem Soc , vol.117 , pp. 3893-3899
    • Shao, J.1    Tam, J.P.2
  • 26
    • 0035451120 scopus 로고    scopus 로고
    • Immunoreactivity of organic mimeotopes of the E2 component of pyruvate dehydrogenase: connecting xenobiotics with primary biliary cirrhosis
    • Long S.A., Quan C., Van de Water J., Nantz M.H., Kurth M.J., Barsky D., et al. Immunoreactivity of organic mimeotopes of the E2 component of pyruvate dehydrogenase: connecting xenobiotics with primary biliary cirrhosis. J Immunol 2001, 167:2956-2963.
    • (2001) J Immunol , vol.167 , pp. 2956-2963
    • Long, S.A.1    Quan, C.2    Van de Water, J.3    Nantz, M.H.4    Kurth, M.J.5    Barsky, D.6
  • 27
    • 0014772602 scopus 로고
    • Color test for detection of free terminal amino groups in the solid-phase synthesis of peptides
    • Kaiser E., Colescott R.L., Bossinger C.D., Cook P.I. Color test for detection of free terminal amino groups in the solid-phase synthesis of peptides. Anal Biochem 1970, 34:595-598.
    • (1970) Anal Biochem , vol.34 , pp. 595-598
    • Kaiser, E.1    Colescott, R.L.2    Bossinger, C.D.3    Cook, P.I.4
  • 28
    • 67149095289 scopus 로고    scopus 로고
    • Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants
    • Hirschfield G.M., Liu X., Xu C., Lu Y., Xie G., Gu X., et al. Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants. N Engl J Med 2009, 360:2544-2555.
    • (2009) N Engl J Med , vol.360 , pp. 2544-2555
    • Hirschfield, G.M.1    Liu, X.2    Xu, C.3    Lu, Y.4    Xie, G.5    Gu, X.6
  • 29
    • 71649102108 scopus 로고    scopus 로고
    • The genetics of human autoimmune disease
    • Invernizzi P., Gershwin M.E. The genetics of human autoimmune disease. J Autoimmun 2009, 33:290-299.
    • (2009) J Autoimmun , vol.33 , pp. 290-299
    • Invernizzi, P.1    Gershwin, M.E.2
  • 30
    • 77649185475 scopus 로고    scopus 로고
    • Drugs and autoimmunity-a contemporary review and mechanistic approach
    • Chang C., Gershwin M.E. Drugs and autoimmunity-a contemporary review and mechanistic approach. J Autoimmun 2010, 34:J266-J275.
    • (2010) J Autoimmun , vol.34
    • Chang, C.1    Gershwin, M.E.2
  • 31
    • 36348950863 scopus 로고    scopus 로고
    • Antimitochondrial antibodies in acute liver failure: implications for primary biliary cirrhosis
    • Leung P.S., Rossaro L., Davis P.A., Park O., Tanaka A., Kikuchi K., et al. Antimitochondrial antibodies in acute liver failure: implications for primary biliary cirrhosis. Hepatology 2007, 46:1436-1442.
    • (2007) Hepatology , vol.46 , pp. 1436-1442
    • Leung, P.S.1    Rossaro, L.2    Davis, P.A.3    Park, O.4    Tanaka, A.5    Kikuchi, K.6
  • 32
    • 30344461594 scopus 로고    scopus 로고
    • The molecular toxicology of acetaminophen
    • David Josephy P. The molecular toxicology of acetaminophen. Drug Metab Rev 2005, 37:581-594.
    • (2005) Drug Metab Rev , vol.37 , pp. 581-594
    • David Josephy, P.1
  • 33
    • 0024241218 scopus 로고
    • The metabolism of N-acetyl-3,5-dimethyl-p-benzoquinone imine in isolated hepatocytes involves N-deacetylation
    • Rossi L., McGirr L.G., Silva J., O'Brien P.J. The metabolism of N-acetyl-3,5-dimethyl-p-benzoquinone imine in isolated hepatocytes involves N-deacetylation. Mol Pharmacol 1988, 34:674-681.
    • (1988) Mol Pharmacol , vol.34 , pp. 674-681
    • Rossi, L.1    McGirr, L.G.2    Silva, J.3    O'Brien, P.J.4
  • 34
    • 34548133006 scopus 로고    scopus 로고
    • Acetaminophen hepatotoxicity
    • vi
    • Larson A.M. Acetaminophen hepatotoxicity. Clin Liver Dis 2007, 11:525-548. vi.
    • (2007) Clin Liver Dis , vol.11 , pp. 525-548
    • Larson, A.M.1
  • 35
    • 10644262224 scopus 로고    scopus 로고
    • Sidechain biology and the immunogenicity of PDC-E2, the major autoantigen of primary biliary cirrhosis
    • Mao T.K., Davis P.A., Odin J.A., Coppel R.L., Gershwin M.E. Sidechain biology and the immunogenicity of PDC-E2, the major autoantigen of primary biliary cirrhosis. Hepatology 2004, 40:1241-1248.
    • (2004) Hepatology , vol.40 , pp. 1241-1248
    • Mao, T.K.1    Davis, P.A.2    Odin, J.A.3    Coppel, R.L.4    Gershwin, M.E.5
  • 36
    • 0034953329 scopus 로고    scopus 로고
    • Bcl-2-dependent oxidation of pyruvate dehydrogenase-E2, a primary biliary cirrhosis autoantigen, during apoptosis
    • Odin J.A., Huebert R.C., Casciola-Rosen L., LaRusso N.F., Rosen A. Bcl-2-dependent oxidation of pyruvate dehydrogenase-E2, a primary biliary cirrhosis autoantigen, during apoptosis. J Clin Invest 2001, 108:223-232.
    • (2001) J Clin Invest , vol.108 , pp. 223-232
    • Odin, J.A.1    Huebert, R.C.2    Casciola-Rosen, L.3    LaRusso, N.F.4    Rosen, A.5
  • 38
    • 77956627699 scopus 로고    scopus 로고
    • Biliary apotopes and anti-mitochondrial antibodies activate innate immune responses in primary biliary cirrhosis
    • Lleo A., Bowlus C.L., Yang G.X., Invernizzi P., Podda M., Van de Water J., et al. Biliary apotopes and anti-mitochondrial antibodies activate innate immune responses in primary biliary cirrhosis. Hepatology 2010, 52:987-998.
    • (2010) Hepatology , vol.52 , pp. 987-998
    • Lleo, A.1    Bowlus, C.L.2    Yang, G.X.3    Invernizzi, P.4    Podda, M.5    Van de Water, J.6
  • 39
    • 71649095850 scopus 로고    scopus 로고
    • Serum inflammatory cytokines, complement components, and soluble interleukin 2 receptor in primary biliary cirrhosis
    • Barak V., Selmi C., Schlesinger M., Blank M., Agmon-Levin N., Kalickman I., et al. Serum inflammatory cytokines, complement components, and soluble interleukin 2 receptor in primary biliary cirrhosis. J Autoimmun 2009, 33:178-182.
    • (2009) J Autoimmun , vol.33 , pp. 178-182
    • Barak, V.1    Selmi, C.2    Schlesinger, M.3    Blank, M.4    Agmon-Levin, N.5    Kalickman, I.6
  • 42
    • 0343554627 scopus 로고    scopus 로고
    • Persistence of autoantibodies against recombinant mitochondrial and nuclear pore proteins after orthotopic liver transplantation for primary biliary cirrhosis
    • Mattalia A., Luttig B., Rosina F., Leung P.S., Van de Water J., Bauducci M., et al. Persistence of autoantibodies against recombinant mitochondrial and nuclear pore proteins after orthotopic liver transplantation for primary biliary cirrhosis. J Autoimmun 1997, 10:491-497.
    • (1997) J Autoimmun , vol.10 , pp. 491-497
    • Mattalia, A.1    Luttig, B.2    Rosina, F.3    Leung, P.S.4    Van de Water, J.5    Bauducci, M.6
  • 43
    • 0142231998 scopus 로고    scopus 로고
    • Mechanisms leading to autoantibody production: link between inflammation and autoimmunity
    • Ohmori H., Kanayama N. Mechanisms leading to autoantibody production: link between inflammation and autoimmunity. Curr Drug Targets Inflamm Allergy 2003, 2:232-241.
    • (2003) Curr Drug Targets Inflamm Allergy , vol.2 , pp. 232-241
    • Ohmori, H.1    Kanayama, N.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.