Proteolytic cleavage of chemerin protein is necessary for activation to the active form, chem157S, which functions as a signaling molecule in glioblastoma

Journal of Biological Chemistry

Volumn 286, Issue 45, 2011, Pages 39510-39519

  Yamaguchi, Yasuto ^a   Du, Xiao Yan ^a   Zhao, Lei ^a   Morser, John ^a,c   Leung, Lawrence L K ^b,c  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VA PALO ALTO HEALTH CARE SYSTEM   (United States)

^c MC5156 ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTIVE IMMUNITY; ADIPOCYTE DIFFERENTIATION; AGONIST ACTIVITY; C TERMINUS; CEREBRO SPINAL FLUIDS; CHEMOATTRACTANTS; CHEMOKINES; EDMAN DEGRADATION; GLIOBLASTOMAS; IN-SILICO; ISOFORMS; MOLAR RATIO; PROTEOLYTIC CLEAVAGE; PROTEOLYTIC PROCESSING; SIGNALING MOLECULES;

BIOCHEMISTRY; MASS SPECTROMETRY; TISSUE;

ASSAYS;

CALCIUM ION; CHEM155A PROTEIN; CHEM157S PROTEIN; CHEM163S PROTEIN; CHEMERIN PROTEIN; CHEMERIN RECEPTOR; CHEMOATTRACTANT; CHEMOKINE RECEPTOR; ISOPROTEIN; MESSENGER RNA; PLASMIN; RECEPTOR; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CALCIUM MOBILIZATION; CALCIUM TRANSPORT; CANCER GRADING; CARBOXY TERMINAL SEQUENCE; CHEMOTAXIS; COMPUTER MODEL; CONTROLLED STUDY; ENZYME ACTIVITY; GLIOBLASTOMA; HUMAN; HUMAN CELL; METHODOLOGY; MOLECULAR BIOLOGY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN CEREBROSPINAL FLUID LEVEL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; SIGNAL TRANSDUCTION;

ANIMALS; CHEMOKINES; CHO CELLS; CRICETINAE; CRICETULUS; FIBRINOLYSIN; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIOBLASTOMA; HUMANS; NEOPLASM PROTEINS; PROTEIN ISOFORMS; PROTEIN STRUCTURE, TERTIARY; PROTEOLYSIS; RECEPTORS, CHEMOKINE; RECOMBINANT PROTEINS; RNA, MESSENGER; RNA, NEOPLASM; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED;

EID: 80655149469     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.258921     Document Type: Article

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