Effects of lowered serotonin transmission on cocaine-induced striatal dopamine response: PET [ 11C]raclopride study in humans

British Journal of Psychiatry

Volumn 199, Issue 5, 2011, Pages 391-397

  Cox, Sylvia M L ^a   Benkelfat, Chawki ^a   Dagher, Alain ^a   Delaney, J Scott ^a   Durand, France ^a   Kolivakis, Theodore ^a   Casey, Kevin F ^a   Leyton, Marco ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

COCAINE; DOPAMINE; RACLOPRIDE C 11; SEROTONIN; TRYPTOPHAN;

ADULT; AMINO ACID BLOOD LEVEL; ARTICLE; DOPAMINERGIC SYSTEM; EUPHORIA; FEMALE; HUMAN; MALE; NEUROTRANSMISSION; POSITRON EMISSION TOMOGRAPHY; SELF REPORT; SEROTONIN RELEASE; VISUAL ANALOG SCALE; WITHDRAWAL SYNDROME;

ADMINISTRATION, INTRANASAL; ADULT; ANALYSIS OF VARIANCE; COCAINE; COCAINE-RELATED DISORDERS; CORPUS STRIATUM; DOPAMINE; DOPAMINE UPTAKE INHIBITORS; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; POSITRON-EMISSION TOMOGRAPHY; RACLOPRIDE; RADIOPHARMACEUTICALS; SEROTONIN; TRYPTOPHAN; YOUNG ADULT;

EID: 80655148028     PISSN: 00071250     EISSN: 14721465     Source Type: Journal    
DOI: 10.1192/bjp.bp.110.084178     Document Type: Article

References (39)

1. Virkkunen M, Rawlings R, Tokola R, Poland RE, Guidotti A, Nemeroff C, et al. CSF biochemistries, glucose metabolism, and diurnal activity rhythms in alcoholic, violent offenders, fire setters, and healthy volunteers. Arch Gen Psychiatry 1994; 51: 20-7. (Pubitemid 24028994)
2. Leyton M, Okazawa H, Diksic M, Paris J, Rosa P, Mzengeza S, et al. Brain regional alpha-[11C]methyl-L-tryptophan trapping in impulsive subjects with borderline personality disorder. Am J Psychiatry 2001; 158: 775-82. (Pubitemid 32429847)
3. Seo D, Patrick CJ, Kennealy PJ. Role of serotonin and dopamine system interactions in the neurobiology of impulsive aggression and its comorbidity with other clinical disorders. Aggress Violent Behav 2008; 13: 383-95.
4. Kapur S, Remington G. Serotonin-dopamine interaction and its relevance to schizophrenia. Am J Psychiatry 1996; 153: 466-76. (Pubitemid 26113309)
5. Guan XM, McBride WJ. Serotonin microinfusion into the ventral tegmental area increases accumbens dopamine release. Brain Res Bull 1989; 23: 541-7. (Pubitemid 20035318)
6. Minabe Y, Emori K, Ashby CR Jr. The depletion of brain serotonin levels by para-chlorophenylalanine administration significantly alters the activity of midbrain dopamine cells in rats: an extracellular single cell recording study. Synapse 1996; 22: 46-53. (Pubitemid 26020415)
7. Carta M, Collu M, Fadda F, Stancampiano R. Augmented cocaine-induced accumbal dopamine efflux, motor activity and place preference in rats fed with a tryptophan-deficient diet. Neurosci Lett 2006; 401: 125-9.
8. Czoty PW, Ginsburg BC, Howell LL. Serotonergic attenuation of the reinforcing and neurochemical effects of cocaine in squirrel monkeys. J Pharmacol Exp Ther 2002; 300: 831-7. (Pubitemid 34164986)
9. Molina PE, Ahmed N, Gatley J, Volkow ND, Abumrad NN. L-tryptophan attenuation of the dopaminergic and behavioral responses to cocaine. Life Sci 2001; 69: 1897-906. (Pubitemid 32835272)
10. Fletcher PJ, Korth KM, Chambers JW. Selective destruction of brain serotonin neurons by 5,7-dihydroxytryptamine increases responding for a conditioned reward. Psychopharmacology (Berl) 1999; 147: 291-9. (Pubitemid 30010550)
11. Walsh SL, Cunningham KA. Serotonergic mechanisms involved in the discriminative stimulus, reinforcing and subjective effects of cocaine. Psychopharmacology (Berl) 1997; 130: 41-58. (Pubitemid 27107783)
12. Peltier R, Schenk S. Effects of serotonergic manipulations on cocaine self-administration in rats. Psychopharmacology (Berl) 1993; 110: 390-4. (Pubitemid 23074560)
13. Cox SM, Benkelfat C, Dagher A, Delaney JS, Durand F, McKenzie SA, et al. Striatal dopamine responses to intranasal cocaine self-administration in humans. Biol Psychiatry 2009; 65: 846-50.
14. First MB, Spitzer RL, Gibbon M, Williams JBW. Structural Clinical Interview for DSM-IV-TR Axis I Disorders: Research Version, Non-patient Edition. (SCID-I/NP). Biometrics Research, 2002.
15. Heatherton TF, Kozlowski LT, Frecker RC, Fagerstrom KO. The Fagerstrom Test for Nicotine Dependence: a revision of the Fagerstrom Tolerance Questionnaire. Br J Addict 1991; 86: 1119-27.
16. Young SN, Smith SE, Pihl RO, Ervin FR. Tryptophan depletion causes a rapid lowering of mood in normal males. Psychopharmacology (Berl) 1985; 87: 173-7. (Pubitemid 16253342)
17. Sled JG, Zijdenbos AP, Evans AC. A nonparametric method for automatic correction of intensity nonuniformity in MRI data. IEEE Trans Med Imaging 1998; 17: 87-97. (Pubitemid 128742012)
18. Talairach J, Tournoux P. Co-planar Stereotaxic Atlas of the Human Brain. Georg Thieme Verlag, 1988.
19. Collins DL, Neelin P, Peters TM, Evans AC. Automatic 3D intersubject registration of MR volumetric data in standardized Talairach space. J Comput Assist Tomogr 1994; 18: 192-205. (Pubitemid 24100002)
20. Evans AC, Marrett S, Neelin P, Collins L, Worsley K, Dai W, et al. Anatomical mapping of functional activation in stereotactic coordinate space. Neuroimage 1992; 1: 43-53.
21. Costes N, Dagher A, Larcher K, Evans AC, Collins DL, Reilhac A. Motion correction of multi-frame PET data in neuroreceptor mapping: simulation based validation. Neuroimage 2009; 47: 1496-505.
22. Gunn RN, Lammertsma AA, Hume SP, Cunningham VJ. Parametric imaging of ligand-receptor binding in PET using a simplified reference region model. Neuroimage 1997; 6: 279-87. (Pubitemid 28018717)
23. Laruelle M. Imaging synaptic neurotransmission with in vivo binding competition techniques: a critical review. J Cereb Blood Flow Metab 2000; 20: 423-51. (Pubitemid 30164887)
24. Aston JA, Gunn RN, Worsley KJ, Ma Y, Evans AC, Dagher A. A statistical method for the analysis of positron emission tomography neuroreceptor ligand data. Neuroimage 2000; 12: 245-56.
25. Worsley KJ, Marrett S, Neelin P, Vandal AC, Friston KJ, Evans AC. A unified statistical approach for determining significant signals in images of cerebral activation. Hum Brain Mapp 1996; 4: 58-73. (Pubitemid 26195721)
26. Hervé D, Pickel VM, Joh TH, Beaudet A. Serotonin axon terminals in the ventral tegmental area of the rat: fine structure and synaptic input to dopaminergic neurons. Brain Res 1987; 435: 71-83. (Pubitemid 18009774)
27. Fibiger HC, Miller JJ. An anatomical and electrophysiological investigation of the serotonergic projection from the dorsal raphe nucleus to the substantia nigra in the rat. Neuroscience 1977; 2: 975-87.
28. Carta M, Fadda F, Stancampiano R. Tryptophan-deficient diet increases the neurochemical and behavioral response to amphetamine. Brain Res 2006; 1094: 86-91. (Pubitemid 43927621)
29. Gervais J, Rouillard C. Dorsal raphe stimulation differentially modulates dopaminergic neurons in the ventral tegmental area and substantia nigra. Synapse 2000; 35: 281-91. (Pubitemid 30090557)
30. Haber SN, Kim KS, Mailly P, Calzavara R. Reward-related cortical inputs define a large striatal region in primates that interface with associative cortical connections, providing a substrate for incentive-based learning. J Neurosci 2006; 26: 8368-76. (Pubitemid 44309851)
31. Robinson, TE, Berridge KC. Review. The incentive sensitization theory of addiction: some current issues. Philos Trans R Soc Lond B Biol Sci 2008; 363: 3137-46.
32. Grace AA, Floresco SB, Goto Y, Lodge DJ. Regulation of firing of dopaminergic neurons and control of goal-directed behaviors. Trends Neurosci 2007; 30: 220-7. (Pubitemid 46654234)
33. Koob GF, Volkow ND. Neurocircuitry of addiction. Neuropsychopharmacology 2010; 35: 217-38.
34. Leyton, M. The neurobiology of desire: dopamine and the regulation of mood and motivational states in humans. In Pleasures of the Brain (eds ML Kringelbach, KC Berridge). Oxford University Press, 2009.
35. Schultz W. Behavioral dopamine signals. Trends Neurosci 2007; 30: 203-10. (Pubitemid 46654238)
36. Phillips AG, Vacca G, Ahn S. A top-down perspective on dopamine, motivation and memory. Pharmacol Biochem Behav 2008; 90: 236-49. (Pubitemid 351790712)
37. McDonald RJ, White NM. A triple dissociation of memory systems: hippocampus, amygdala, and dorsal striatum. Behav Neurosci 1993; 107: 3-22. (Pubitemid 23187254)
38. Everitt BJ, Robbins TW. Neural systems of reinforcement for drug addiction: from actions to habits to compulsion. Nat Neurosci 2005; 8: 1481-9. (Pubitemid 41573659)
39. Aronson SC, Black JE, McDougle CJ, Scanley BE, Jatlow P, Kosten TR, et al. Serotonergic mechanisms of cocaine effects in humans. Psychopharmacology (Berl) 1995; 119: 179-85.