Striatal Dopamine Responses to Intranasal Cocaine Self-Administration in Humans

Biological Psychiatry

Volumn 65, Issue 10, 2009, Pages 846-850

  Cox, Sylvia M L ^a   Benkelfat, Chawki ^a   Dagher, Alain ^a   Delaney, J Scott ^a   Durand, France ^a   McKenzie, Samuel A ^a   Kolivakis, Theodore ^a   Casey, Kevin F ^a   Leyton, Marco ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

Cocaine; cortisol; dopamine; reward; sensitization; vulnerability

Indexed keywords

COCAINE; DOPAMINE; PLACEBO; PSYCHOSTIMULANT AGENT; RACLOPRIDE C 11;

ADULT; ARTICLE; CLINICAL ARTICLE; COCAINE DEPENDENCE; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINE BLOOD LEVEL; DOPAMINERGIC ACTIVITY; DRUG SELF ADMINISTRATION; DRUG SENSITIVITY; DRUG USE; FEMALE; HUMAN; LIFESPAN; MALE; POSITRON EMISSION TOMOGRAPHY; PREDICTION; PRIORITY JOURNAL; PUTAMEN; STRIATE CORTEX; SUBSTANCE ABUSE;

ADMINISTRATION, INTRANASAL; BASAL GANGLIA; COCAINE; DOPAMINE; FEMALE; HUMANS; HYDROCORTISONE; MALE; PHENYLALANINE; POSITRON-EMISSION TOMOGRAPHY; PUTAMEN; RACLOPRIDE; RECEPTORS, DOPAMINE D2; SELF ADMINISTRATION; TYROSINE; YOUNG ADULT;

EID: 65049088481     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopsych.2009.01.021     Document Type: Article

References (35)

1. Di Chiara G., and Imperato A. Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats. Proc Natl Acad Sci U S A 85 (1988) 5274-5278
2. Di Ciano P., Blaha C.D., and Phillips A.G. Changes in dopamine oxidation currents in the nucleus accumbens during unlimited-access self-administration of d-amphetamine by rats. Behav Pharmacol 7 (1996) 714-729
3. Hemby S.E., Co C., Koves T.R., Smith J.E., and Dworkin S.I. Differences in extracellular dopamine concentrations in the nucleus accumbens during response-dependent and response-independent cocaine administration in the rat. Psychopharmacology (Berl) 133 (1997) 7-16
4. Stewart J., de Wit H., and Eikelboom R. Role of unconditioned and conditioned drug effects in the self-administration of opiates and stimulants. Psychol Rev 91 (1984) 251-268
5. Robinson T.E., and Berridge K.C. Review. The incentive sensitization theory of addiction: some current issues. Philos Trans R Soc Lond B Biol Sci 363 (2008) 3137-3146
6. Leyton M. Conditioned and sensitized responses to stimulant drugs in humans. Prog Neuropsychopharmacol Biol Psychiatry 31 (2007) 1601-1613
7. Volkow N.D., Fowler J.S., Wang G.J., Swanson J.M., and Telang F. Dopamine in drug abuse and addiction: results of imaging studies and treatment implications. Arch Neurol 64 (2007) 1575-1579
8. Volkow N.D., Wang G.J., Fischman M.W., Foltin R.W., Fowler J.S., Abumrad N.N., et al. Relationship between subjective effects of cocaine and dopamine transporter occupancy. Nature 386 (1997) 827-830
9. Schlaepfer T.E., Pearlson G.D., Wong D.F., Marenco S., and Dannals R.F. PET study of competition between intravenous cocaine and [11C]raclopride at dopamine receptors in human subjects. Am J Psychiatry 154 (1997) 1209-1213
10. First M.B., Spitzer R.L., Gibbon M., and Williams J.B.W. Structural Clinical Interview for DSM-IV-TR Axis I Disorders, Research Version, Nonpatient Edition. (SCID-I/NP) (2002), Biometrics Research, New York State Psychiatric Institute, New York
11. Heatherton T.F., Kozlowski L.T., Frecker R.C., and Fagerstrom K.O. The Fagerstrom Test for Nicotine Dependence: a revision of the Fagerstrom Tolerance Questionnaire. Br J Addict 86 (1991) 1119-1127
12. Young S.N., Smith S.E., Pihl R.O., and Ervin F.R. Tryptophan depletion causes a rapid lowering of mood in normal males. Psychopharmacology (Berl) 87 (1985) 173-177
13. Sled J.G., Zijdenbos A.P., and Evans A.C. A nonparametric method for automatic correction of intensity nonuniformity in MRI data. IEEE Trans Med Imaging 17 (1998) 87-97
14. Talairach J., and Tournoux P. Co-planar Stereotaxic Atlas of the Human Brain (1988), Georg Thieme Verlag, Stuttgart, Germany
15. Collins D.L., Neelin P., Peters T.M., and Evans A.C. Automatic 3D intersubject registration of MR volumetric data in standardized Talairach space. J Comput Assist Tomogr 18 (1994) 192-205
16. Evans A.C., Marrett S., Neelin P., Collins L., Worsley K., Dai W., et al. Anatomical mapping of functional activation in stereotactic coordinate space. Neuroimage 1 (1992) 43-53
17. Perruchot F., Reilhac A., Grova C., Evans A.C., and Dagher A. Motion correction of multi-frame PET data. IEEE 5 (2004) 3186-3190 Presented at the IEEE Nuclear Science Symposium and Medical Imaging Conference, Honolulu, Hawaii.
18. Gunn R.N., Lammertsma A.A., Hume S.P., and Cunningham V.J. Parametric imaging of ligand-receptor binding in PET using a simplified reference region model. Neuroimage 6 (1997) 279-287
19. Aston J.A., Gunn R.N., Worsley K.J., Ma Y., Evans A.C., and Dagher A. A statistical method for the analysis of positron emission tomography neuroreceptor ligand data. Neuroimage 12 (2000) 245-256
20. Worsley K.J., Marrett S., Neelin P., Vandal A.C., Friston K.J., and Evans A.C. A unified statistical approach for determining significant signals in images of cerebral activation. Human Brain Mapping 4 (1996) 58-73
21. Mawlawi O., Martinez D., Slifstein M., Broft A., Chatterjee R., Hwang D.R., et al. Imaging human mesolimbic dopamine transmission with positron emission tomography: I. Accuracy and precision of D(2) receptor parameter measurements in ventral striatum. J Cereb Blood Flow Metab 21 (2001) 1034-1057
22. Martinez D., Slifstein M., Broft A., Mawlawi O., Hwang D.R., Huang Y., et al. Imaging human mesolimbic dopamine transmission with positron emission tomography. Part II: amphetamine-induced dopamine release in the functional subdivisions of the striatum. J Cereb Blood Flow Metab 23 (2003) 285-300
23. Collins D.L., Holmes C.J., Peters T.M., and Evans A.C. Automatic 3D model-based neuroanatomical segmentation. Human Brain Mapping 3 (1995) 190-208
24. Bradberry C.W., Barrett-Larimore R.L., Jatlow P., and Rubino S.R. Impact of self-administered cocaine and cocaine cues on extracellular dopamine in mesolimbic and sensorimotor striatum in rhesus monkeys. J Neurosci 20 (2000) 3874-3883
25. Stewart J. Neurobiology of conditioning to drugs of abuse. In: Kalivas P., and Samson H. (Eds). The Neurobiology of Drug and Alcohol Addiction (1992), New York Academy of Sciences, New York 335-346
26. Leyton M. The neurobiology of desire: Dopamine and the regulation of mood and motivational states in humans. In: Berridge K.C., and Kringelbach M.L. (Eds). Pleasures of the Brain (2009), Oxford University Press, Oxford
27. Leyton M., Boileau I., Benkelfat C., Diksic M., Baker G., and Dagher A. Amphetamine-induced increases in extracellular dopamine, drug wanting, and novelty seeking: A PET/[11C]raclopride study in healthy men. Neuropsychopharmacology 27 (2002) 1027-1035
28. Vezina P. Sensitization of midbrain dopamine neuron reactivity and the self-administration of psychomotor stimulant drugs. Neurosci Biobehav Rev 27 (2004) 827-839
29. Kalivas P.W., and Stewart J. Dopamine transmission in the initiation and expression of drug- and stress-induced sensitization of motor activity. Brain Res Brain Res Rev 16 (1991) 223-244
30. Boileau I., Dagher A., Leyton M., Gunn R.N., Baker G.B., Diksic M., et al. Modeling sensitization to stimulants in humans: An [11C]raclopride/positron emission tomography study in healthy men. Arch Gen Psychiatry 63 (2006) 1386-1395
31. Volkow N.D., Wang G.J., Fowler J.S., Logan J., Gatley S.J., Hitzemann R., et al. Decreased striatal dopaminergic responsiveness in detoxified cocaine-dependent subjects. Nature 386 (1997) 830-833
32. Martinez D., Narendran R., Foltin R.W., Slifstein M., Hwang D.R., Broft A., et al. Amphetamine-induced dopamine release: markedly blunted in cocaine dependence and predictive of the choice to self-administer cocaine. Am J Psychiatry 164 (2007) 622-629
33. Chefer V.I., and Shippenberg T.S. Changes in basal and cocaine-evoked extracellular dopamine uptake and release in the rat nucleus accumbens during early abstinence from cocaine: Quantitative determination under transient conditions. Neuroscience 112 (2002) 907-919
34. Di Ciano P., Blaha C.D., and Phillips A.G. Inhibition of dopamine efflux in the rat nucleus accumbens during abstinence after free access to d-amphetamine. Behav Brain Res 128 (2002) 1-12
35. Vezina P., and Leyton M. Conditioned cues and the expression of stimulant sensitization in animals and humans. Neuropharmacology 56 suppl 1 (2009) 160-168