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Volumn 60, Issue 12, 2011, Pages 1754-1763

Early use of immunosuppressives or TNF antagonists for the treatment of Crohn's disease: Time for a change

Author keywords

[No Author keywords available]

Indexed keywords

6 MERCAPTOPURINE DERIVATIVE; ADALIMUMAB; AZATHIOPRINE; BIOLOGICAL MARKER; CERTOLIZUMAB PEGOL; CORTICOSTEROID; IMMUNOSUPPRESSIVE AGENT; INFLIXIMAB; MERCAPTOPURINE; METHOTREXATE; PLACEBO; PREDNISONE; TUMOR NECROSIS FACTOR INHIBITOR;

EID: 80655133081     PISSN: 00175749     EISSN: 14683288     Source Type: Journal    
DOI: 10.1136/gutjnl-2011-300934     Document Type: Review
Times cited : (113)

References (83)
  • 2
    • 0035188740 scopus 로고    scopus 로고
    • Behaviour of Crohn's disease according to the Vienna classification: Changing pattern over the course of the disease
    • DOI 10.1136/gut.49.6.777
    • Louis E, Collard A, Oger AF, et al. Behaviour of Crohn's disease according to the Vienna classification: changing pattern over the course of the disease. Gut 2001;49:777-82. (Pubitemid 33096034)
    • (2001) Gut , vol.49 , Issue.6 , pp. 777-782
    • Louis, E.1    Collard, A.2    Oger, A.F.3    Degroote, E.4    Aboul, N.E.Y.F.5    Belaiche, J.6
  • 4
    • 77957346794 scopus 로고    scopus 로고
    • Risk factors associated with progression to intestinal complications of Crohn's disease in a population-based cohort
    • Thia KT, Sandborn WJ, Harmsen WS, et al. Risk factors associated with progression to intestinal complications of Crohn's disease in a population-based cohort. Gastroenterology 2010;139:1147-55.
    • (2010) Gastroenterology , vol.139 , pp. 1147-1155
    • Thia, K.T.1    Sandborn, W.J.2    Harmsen, W.S.3
  • 5
    • 70450164329 scopus 로고    scopus 로고
    • Endpoints for clinical trials evaluating disease modification and structural damage in adults with Crohn's disease
    • D'Haens GR, Fedorak R, Lemann M, et al. Endpoints for clinical trials evaluating disease modification and structural damage in adults with Crohn's disease. Inflamm Bowel Dis 2009;15:1599-604.
    • (2009) Inflamm Bowel Dis , vol.15 , pp. 1599-1604
    • D'Haens, G.R.1    Fedorak, R.2    Lemann, M.3
  • 6
    • 77953718691 scopus 로고    scopus 로고
    • Current evidence for a strategic approach to the management of rheumatoid arthritis with disease-modifying antirheumatic drugs: A systematic literature review informing the EULAR recommendations for the management of rheumatoid arthritis
    • Knevel R, Schoels M, Huizinga TW, et al. Current evidence for a strategic approach to the management of rheumatoid arthritis with disease-modifying antirheumatic drugs: a systematic literature review informing the EULAR recommendations for the management of rheumatoid arthritis. Ann Rheum Dis 2010;69:987-94.
    • (2010) Ann Rheum Dis , vol.69 , pp. 987-994
    • Knevel, R.1    Schoels, M.2    Huizinga, T.W.3
  • 7
    • 77954984854 scopus 로고    scopus 로고
    • Efficacy of initial methotrexate monotherapy versus combination therapy with a biological agent in early rheumatoid arthritis: A meta-analysis of clinical and radiographic remission
    • Kuriya B, Arkema EV, Bykerk VP, et al. Efficacy of initial methotrexate monotherapy versus combination therapy with a biological agent in early rheumatoid arthritis: a meta-analysis of clinical and radiographic remission. Ann Rheum Dis 2010;69:1298-304.
    • (2010) Ann Rheum Dis , vol.69 , pp. 1298-1304
    • Kuriya, B.1    Arkema, E.V.2    Bykerk, V.P.3
  • 8
    • 67549115310 scopus 로고    scopus 로고
    • Clinical and radiological efficacy of initial vs delayed treatment with infliximab plus methotrexate in patients with early rheumatoid arthritis
    • van der Kooij SM, le Cessie S, Goekoop-Ruiterman YP, et al. Clinical and radiological efficacy of initial vs delayed treatment with infliximab plus methotrexate in patients with early rheumatoid arthritis. Ann Rheum Dis 2009;68:1153-8.
    • (2009) Ann Rheum Dis , vol.68 , pp. 1153-1158
    • Van Der Kooij, S.M.1    Le Cessie, S.2    Goekoop-Ruiterman, Y.P.3
  • 9
    • 77149169736 scopus 로고    scopus 로고
    • Early Crohn disease: A proposed definition for use in disease-modification trials
    • Peyrin-Biroulet L, Loftus EV Jr, Colombel JF, et al. Early Crohn disease: a proposed definition for use in disease-modification trials. Gut 2010;59:141-7.
    • (2010) Gut , vol.59 , pp. 141-147
    • Peyrin-Biroulet, L.1    Loftus Jr., E.V.2    Colombel, J.F.3
  • 10
    • 58149393184 scopus 로고    scopus 로고
    • Perianal disease predicts changes in Crohn's disease phenotype-results of a population-based study of inflammatory bowel disease phenotype
    • Tarrant KM, Barclay ML, Frampton CM, et al. Perianal disease predicts changes in Crohn's disease phenotype-results of a population-based study of inflammatory bowel disease phenotype. Am J Gastroenterol 2008;103:3082-93.
    • (2008) Am J Gastroenterol , vol.103 , pp. 3082-3093
    • Tarrant, K.M.1    Barclay, M.L.2    Frampton, C.M.3
  • 13
    • 79955844087 scopus 로고    scopus 로고
    • Development of the Crohn's disease digestive damage score, the Lemann score
    • Pariente B, Cosnes J, Danese S, et al. Development of the Crohn's disease digestive damage score, the Lemann score. Inflamm Bowel Dis 2011;17:1415-22.
    • (2011) Inflamm Bowel Dis , vol.17 , pp. 1415-1422
    • Pariente, B.1    Cosnes, J.2    Danese, S.3
  • 14
    • 53249121838 scopus 로고    scopus 로고
    • The International Classification of Functioning Disability and Health: Its development process and content validity
    • Cieza A, Stucki G. The International Classification of Functioning Disability and Health: its development process and content validity. Eur J Phys Rehabil Med 2008;44:303-13.
    • (2008) Eur J Phys Rehabil Med , vol.44 , pp. 303-313
    • Cieza, A.1    Stucki, G.2
  • 17
    • 4344602852 scopus 로고    scopus 로고
    • Guidelines for the management of inflammatory bowel disease in adults
    • Carter MJ, Lobo AJ, Travis SP. Guidelines for the management of inflammatory bowel disease in adults. Gut 2004;53(Suppl 5):V1-16.
    • (2004) Gut , vol.53 , Issue.SUPPL. 5
    • Carter, M.J.1    Lobo, A.J.2    Travis, S.P.3
  • 18
    • 0028267896 scopus 로고
    • Frequency of glucocorticoid resistance and dependency in Crohn's disease
    • Munkholm P, Langholz E, Davidsen M, et al. Frequency of glucocorticoid resistance and dependency in Crohn's disease. Gut 1994;35:360-2.
    • (1994) Gut , vol.35 , pp. 360-362
    • Munkholm, P.1    Langholz, E.2    Davidsen, M.3
  • 20
    • 0025219580 scopus 로고
    • Clinical, biological, and endoscopic picture of attacks of Crohn's disease. Evolution on prednisolone
    • Modigliani R, Mary JY, Simon JF, et al. Clinical, biological, and endoscopic picture of attacks of Crohn's disease. Evolution on prednisolone. Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives. Gastroenterology 1990;98:811-18. (Pubitemid 20095830)
    • (1990) Gastroenterology , vol.98 , Issue.4 , pp. 811-818
    • Modigliani, R.1    Mary, J.-Y.2    Simon, J.-F.3    Cortot, A.4    Soule, J.-C.5    Gendre, J.-P.6    Rene, E.7
  • 21
    • 33646147141 scopus 로고    scopus 로고
    • Serious infections and mortality in association with therapies for Crohn's disease: TREAT registry
    • Lichtenstein GR, Feagan BG, Cohen RD, et al. Serious infections and mortality in association with therapies for Crohn's disease: TREAT registry. Clin Gastroenterol Hepatol 2006;4:621-30.
    • (2006) Clin Gastroenterol Hepatol , vol.4 , pp. 621-630
    • Lichtenstein, G.R.1    Feagan, B.G.2    Cohen, R.D.3
  • 22
    • 0028790186 scopus 로고
    • A controlled double blind study of azathioprine in the management of Crohn's disease
    • Candy S, Wright J, Gerber M, et al. A controlled double blind study of azathioprine in the management of Crohn's disease. Gut 1995;37:674-8.
    • (1995) Gut , vol.37 , pp. 674-678
    • Candy, S.1    Wright, J.2    Gerber, M.3
  • 24
    • 67650416300 scopus 로고    scopus 로고
    • Azathioprine or 6-mercaptopurine for maintenance of remission in Crohn's disease
    • CD000067
    • Prefontaine E, Sutherland LR, Macdonald JK, et al. Azathioprine or 6-mercaptopurine for maintenance of remission in Crohn's disease. Cochrane Database Syst Rev 2009;(1):CD000067.
    • (2009) Cochrane Database Syst Rev , Issue.1
    • Prefontaine, E.1    Sutherland, L.R.2    Macdonald, J.K.3
  • 25
    • 0029134702 scopus 로고
    • Azathioprine and 6-mercaptopurine in Crohn disease. A meta-analysis
    • Pearson DC, May GR, Fick GH, et al. Azathioprine and 6-mercaptopurine in Crohn disease. A meta-analysis. Ann Intern Med 1995;123:132-42.
    • (1995) Ann Intern Med , vol.123 , pp. 132-142
    • Pearson, D.C.1    May, G.R.2    Fick, G.H.3
  • 27
  • 28
  • 29
    • 0033770169 scopus 로고    scopus 로고
    • A multicenter trial of 6-mercaptopurine and prednisone in children with newly diagnosed Crohn's disease
    • Markowitz J, Grancher K, Kohn N, et al. A multicenter trial of 6-mercaptopurine and prednisone in children with newly diagnosed Crohn's disease. Gastroenterology 2000;119:895-902.
    • (2000) Gastroenterology , vol.119 , pp. 895-902
    • Markowitz, J.1    Grancher, K.2    Kohn, N.3
  • 30
    • 77956171908 scopus 로고    scopus 로고
    • Factors that determine risk for surgery in pediatric patients with Crohn's disease
    • Schaefer ME, Machan JT, Kawatu D, et al. Factors that determine risk for surgery in pediatric patients with Crohn's disease. Clin Gastroenterol Hepatol 2010;8:789-94.
    • (2010) Clin Gastroenterol Hepatol , vol.8 , pp. 789-794
    • Schaefer, M.E.1    Machan, J.T.2    Kawatu, D.3
  • 31
    • 80655139467 scopus 로고    scopus 로고
    • Early use of azathioprine has a steroid sparing effect on recently diagnosed Crohn's disease patients
    • Presented at
    • Sans M, Lopez-San Roman A, Esteve M, et al. Early use of azathioprine has a steroid sparing effect on recently diagnosed Crohn's disease patients. Presented at Digestive Disease Week, 7-10 May 2011, Chicago.
    • Digestive Disease Week, 7-10 May 2011, Chicago
    • Sans, M.1    Lopez-San Roman, A.2    Esteve, M.3
  • 32
    • 79958228566 scopus 로고    scopus 로고
    • Impact of azathioprine and tumour necrosis factor antagonists on the need for surgery in newly diagnosed Crohn's disease
    • Peyrin-Biroulet L, Oussalah A, Williet N, et al. Impact of azathioprine and tumour necrosis factor antagonists on the need for surgery in newly diagnosed Crohn's disease. Gut 2011;60:930-6.
    • (2011) Gut , vol.60 , pp. 930-936
    • Peyrin-Biroulet, L.1    Oussalah, A.2    Williet, N.3
  • 33
    • 77955096659 scopus 로고    scopus 로고
    • Natural history of Crohn's disease in a population-based cohort from Cardiff (1986-2003): A study of changes in medical treatment and surgical resection rates
    • Ramadas AV, Gunesh S, Thomas GA, et al. Natural history of Crohn's disease in a population-based cohort from Cardiff (1986-2003): a study of changes in medical treatment and surgical resection rates. Gut 2010;59:1200-6.
    • (2010) Gut , vol.59 , pp. 1200-1206
    • Ramadas, A.V.1    Gunesh, S.2    Thomas, G.A.3
  • 34
    • 53049110159 scopus 로고    scopus 로고
    • Natural history of pediatric Crohn's disease: A population-based cohort study
    • Vernier-Massouille G, Balde M, Salleron J, et al. Natural history of pediatric Crohn's disease: a population-based cohort study. Gastroenterology 2008;135:1106-13.
    • (2008) Gastroenterology , vol.135 , pp. 1106-1113
    • Vernier-Massouille, G.1    Balde, M.2    Salleron, J.3
  • 35
    • 12344291265 scopus 로고    scopus 로고
    • Impact of the increasing use of immunosuppressants in Crohn's disease on the need for intestinal surgery
    • DOI 10.1136/gut.2004.045294
    • Cosnes J, Nion-Larmurier I, Beaugerie L, et al. Impact of the increasing use of immunosuppressants in Crohn's disease on the need for intestinal surgery. Gut 2005;54:237-41. (Pubitemid 40139240)
    • (2005) Gut , vol.54 , Issue.2 , pp. 237-241
    • Cosnes, J.1    Nion-Larmurier, I.2    Beaugerie, L.3    Afchain, P.4    Tiret, E.5    Gendre, J.-P.6
  • 36
    • 31044442965 scopus 로고    scopus 로고
    • The PREMIER study: A multicenter, randomized, double-blind clinical trial of combination therapy with adalimumab plus methotrexate versus methotrexate alone or adalimumab alone in patients with early, aggressive rheumatoid arthritis who had not had previous methotrexate treatment
    • DOI 10.1002/art.21519
    • Breedveld FC, Weisman MH, Kavanaugh AF, et al. The PREMIER study: a multicenter, randomized, double-blind clinical trial of combination therapy with adalimumab plus methotrexate versus methotrexate alone or adalimumab alone in patients with early, aggressive rheumatoid arthritis who had not had previous methotrexate treatment. Arthritis Rheum 2006;54:26-37. (Pubitemid 43122183)
    • (2006) Arthritis and Rheumatism , vol.54 , Issue.1 , pp. 26-37
    • Breedveld, F.C.1    Weisman, M.H.2    Kavanaugh, A.F.3    Cohen, S.B.4    Pavelka, K.5    Van Vollenhoven, R.6    Sharp, J.7    Perez, J.L.8    Spencer-Green, G.T.9
  • 38
    • 33644895018 scopus 로고    scopus 로고
    • Predictors of joint damage in patients with early rheumatoid arthritis treated with high-dose methotrexate with or without concomitant infliximab: Results from the ASPIRE trial
    • Smolen JS, Van Der Heijde DM, St Clair EW, et al. Predictors of joint damage in patients with early rheumatoid arthritis treated with high-dose methotrexate with or without concomitant infliximab: results from the ASPIRE trial. Arthritis Rheum 2006;54:702-10.
    • (2006) Arthritis Rheum , vol.54 , pp. 702-710
    • Smolen, J.S.1    Van Der Heijde, D.M.2    St Clair, E.W.3
  • 40
    • 77950988234 scopus 로고    scopus 로고
    • Infliximab, azathioprine, or combination therapy for Crohn's disease
    • Colombel JF, Sandborn WJ, Reinisch W, et al. Infliximab, azathioprine, or combination therapy for Crohn's disease. N Engl J Med 2010;362:1383-95.
    • (2010) N Engl J Med , vol.362 , pp. 1383-1395
    • Colombel, J.F.1    Sandborn, W.J.2    Reinisch, W.3
  • 41
    • 77954423661 scopus 로고    scopus 로고
    • Increased response and remission rates in short-duration Crohn's disease with subcutaneous certolizumab pegol: An analysis of PRECiSE 2 randomized maintenance trial data
    • Schreiber S, Colombel JF, Bloomfield R, et al. Increased response and remission rates in short-duration Crohn's disease with subcutaneous certolizumab pegol: an analysis of PRECiSE 2 randomized maintenance trial data. Am J Gastroenterol 2010;105:1574-82.
    • (2010) Am J Gastroenterol , vol.105 , pp. 1574-1582
    • Schreiber, S.1    Colombel, J.F.2    Bloomfield, R.3
  • 42
    • 34848887711 scopus 로고    scopus 로고
    • Early Crohn's disease shows high levels of remission to therapy with adalimumab: Sub-analysis of CHARM
    • Schreiber S, Reinisch W, Colombel JF, et al. Early Crohn's disease shows high levels of remission to therapy with adalimumab: sub-analysis of CHARM. Gastroenterology 2007;132:147A.
    • (2007) Gastroenterology , vol.132
    • Schreiber, S.1    Reinisch, W.2    Colombel, J.F.3
  • 43
    • 33645958908 scopus 로고    scopus 로고
    • Infliximab plus azathioprine for steroid-dependent Crohn's disease patients: A randomized placebo-controlled trial
    • Lemann M, Mary JY, Duclos B, et al. Infliximab plus azathioprine for steroid-dependent Crohn's disease patients: a randomized placebo-controlled trial. Gastroenterology 2006;130:1054-61.
    • (2006) Gastroenterology , vol.130 , pp. 1054-1061
    • Lemann, M.1    Mary, J.Y.2    Duclos, B.3
  • 44
    • 53049083113 scopus 로고    scopus 로고
    • A randomized trial of methotrexate in combination with infliximab for the treatment of Crohn's disease
    • Feagan BG, MacDonald V, Panaccione R, et al. A randomized trial of methotrexate in combination with infliximab for the treatment of Crohn's disease. Gastroenterology 2008;135:294-5A.
    • (2008) Gastroenterology , vol.135
    • Feagan, B.G.1    MacDonald, V.2    Panaccione, R.3
  • 45
    • 75449114677 scopus 로고    scopus 로고
    • Mucosal healing predicts sustained clinical remission in patients with early-stage Crohn's disease
    • Baert F, Moortgat L, Van Assche G, et al. Mucosal healing predicts sustained clinical remission in patients with early-stage Crohn's disease. Gastroenterology 2010;138:463-8.
    • (2010) Gastroenterology , vol.138 , pp. 463-468
    • Baert, F.1    Moortgat, L.2    Van Assche, G.3
  • 46
    • 33749432435 scopus 로고    scopus 로고
    • Association of Trough Serum Infliximab to Clinical Outcome After Scheduled Maintenance Treatment for Crohn's Disease
    • DOI 10.1016/j.cgh.2006.06.025, PII S154235650600677X
    • Maser EA, Villela R, Silverberg MS, et al. Association of trough serum infliximab to clinical outcome after scheduled maintenance treatment for Crohn's disease. Clin Gastroenterol Hepatol 2006;4:1248-54. (Pubitemid 44512213)
    • (2006) Clinical Gastroenterology and Hepatology , vol.4 , Issue.10 , pp. 1248-1254
    • Maser, E.A.1    Villela, R.2    Silverberg, M.S.3    Greenberg, G.R.4
  • 47
    • 77951974444 scopus 로고    scopus 로고
    • Clinical utility of measuring infliximab and human anti-chimeric antibody concentrations in patients with inflammatory bowel disease
    • Afif W, Loftus EV Jr, Faubion WA, et al. Clinical utility of measuring infliximab and human anti-chimeric antibody concentrations in patients with inflammatory bowel disease. Am J Gastroenterol 2010;105:1133-9.
    • (2010) Am J Gastroenterol , vol.105 , pp. 1133-1139
    • Afif, W.1    Loftus Jr., E.V.2    Faubion, W.A.3
  • 49
    • 58649121974 scopus 로고    scopus 로고
    • Infliximab prevents Crohn's disease recurrence after ileal resection
    • Regueiro M, Schraut W, Baidoo L, et al. Infliximab prevents Crohn's disease recurrence after ileal resection. Gastroenterology 2009;136:441-50.
    • (2009) Gastroenterology , vol.136 , pp. 441-450
    • Regueiro, M.1    Schraut, W.2    Baidoo, L.3
  • 51
    • 34247586997 scopus 로고    scopus 로고
    • Changes in clinical characteristics, course, and prognosis of inflammatory bowel disease during the last 5 decades: A population-based study from Copenhagen, Denmark
    • DOI 10.1002/ibd.20036
    • Jess T, Riis L, Vind I, et al. Changes in clinical characteristics, course, and prognosis of inflammatory bowel disease during the last 5 decades: a population-based study from Copenhagen, Denmark. Inflamm Bowel Dis 2007;13:481-9. (Pubitemid 46668255)
    • (2007) Inflammatory Bowel Diseases , vol.13 , Issue.4 , pp. 481-489
    • Jess, T.1    Riis, L.2    Vind, I.3    Winther, K.V.4    Borg, S.5    Binder, V.6    Langholz, E.7    Thomsen, O.O.8    Munkholm, P.9
  • 52
    • 0029014305 scopus 로고
    • Disease activity courses in a regional cohort of Crohn's disease patients
    • Munkholm P, Langholz E, Davidsen M, et al. Disease activity courses in a regional cohort of Crohn's disease patients. Scand J Gastroenterol 1995;30:699-706.
    • (1995) Scand J Gastroenterol , vol.30 , pp. 699-706
    • Munkholm, P.1    Langholz, E.2    Davidsen, M.3
  • 54
    • 77951569388 scopus 로고    scopus 로고
    • Biomarkers in early rheumatoid arthritis: Longitudinal associations with inflammation and joint destruction measured by magnetic resonance imaging and conventional radiographs
    • Syversen SW, Haavardsholm EA, Boyesen P, et al. Biomarkers in early rheumatoid arthritis: longitudinal associations with inflammation and joint destruction measured by magnetic resonance imaging and conventional radiographs. Ann Rheum Dis 2010;69:845-50.
    • (2010) Ann Rheum Dis , vol.69 , pp. 845-850
    • Syversen, S.W.1    Haavardsholm, E.A.2    Boyesen, P.3
  • 55
    • 77957261808 scopus 로고    scopus 로고
    • Radiographic progression and remission rates in early rheumatoid arthritis - MRI bone oedema and anti-CCP predicted radiographic progression in the 5-year extension of the double-blind randomised CIMESTRA trial
    • Hetland ML, Stengaard-Pedersen K, Junker P, et al. Radiographic progression and remission rates in early rheumatoid arthritis - MRI bone oedema and anti-CCP predicted radiographic progression in the 5-year extension of the double-blind randomised CIMESTRA trial. Ann Rheum Dis 2010;69:1789-95.
    • (2010) Ann Rheum Dis , vol.69 , pp. 1789-1795
    • Hetland, M.L.1    Stengaard-Pedersen, K.2    Junker, P.3
  • 56
    • 0037379422 scopus 로고    scopus 로고
    • Early development of stricturing or penetrating pattern in Crohn's disease is influenced by disease location, number of flares, and smoking but not by NOD2/CARD15 genotype
    • DOI 10.1136/gut.52.4.552
    • Louis E, Michel V, Hugot JP, et al. Early development of stricturing or penetrating pattern in Crohn's disease is influenced by disease location, number of flares, and smoking but not by NOD2/CARD15 genotype. Gut 2003;52:552-7. (Pubitemid 36363410)
    • (2003) Gut , vol.52 , Issue.4 , pp. 552-557
    • Louis, E.1    Michel, V.2    Hugot, J.P.3    Reenaers, C.4    Fontaine, F.5    Delforge, M.6    El, Y.F.7    Colombel, J.F.8    Belaiche, J.9
  • 57
    • 70349567522 scopus 로고    scopus 로고
    • Perianal disease, small bowel disease, smoking, prior steroid or early azathioprine/biological therapy are predictors of disease behavior change in patients with Crohn's disease
    • Lakatos PL, Czegledi Z, Szamosi T, et al. Perianal disease, small bowel disease, smoking, prior steroid or early azathioprine/biological therapy are predictors of disease behavior change in patients with Crohn's disease. World J Gastroenterol 2009;15:3504-10.
    • (2009) World J Gastroenterol , vol.15 , pp. 3504-3510
    • Lakatos, P.L.1    Czegledi, Z.2    Szamosi, T.3
  • 59
    • 0033971379 scopus 로고    scopus 로고
    • Risk factors for surgery and postoperative recurrence in Crohn's disease
    • DOI 10.1097/00000658-200001000-00006
    • Bernell O, Lapidus A, Hellers G. Risk factors for surgery and postoperative recurrence in Crohn's disease. Ann Surg 2000;231:38-45. (Pubitemid 30043937)
    • (2000) Annals of Surgery , vol.231 , Issue.1 , pp. 38-45
    • Bernell, O.1    Lapidus, A.2    Hellers, G.3
  • 62
    • 74049136834 scopus 로고    scopus 로고
    • Disability in inflammatory bowel diseases: Developing ICF Core Sets for patients with inflammatory bowel diseases based on the international classification of functioning, disability, and health
    • Peyrin-Biroulet L, Cieza A, Sandborn WJ, et al. Disability in inflammatory bowel diseases: developing ICF Core Sets for patients with inflammatory bowel diseases based on the international classification of functioning, disability, and health. Inflamm Bowel Dis 2010;16:15-22.
    • (2010) Inflamm Bowel Dis , vol.16 , pp. 15-22
    • Peyrin-Biroulet, L.1    Cieza, A.2    Sandborn, W.J.3
  • 63
    • 84855216805 scopus 로고    scopus 로고
    • Development of the first disability index for inflammatory bowel disease based on the international classification of functioning, disability and health
    • Published Online First: 5 June doi:10.1136/gutjnl-2011-300049
    • Peyrin-Biroulet L, Cieza A, Sandborn WJ, et al. Development of the first disability index for inflammatory bowel disease based on the international classification of functioning, disability and health. Gut. Published Online First: 5 June 2011. doi:10.1136/gutjnl-2011-300049.
    • (2011) Gut
    • Peyrin-Biroulet, L.1    Cieza, A.2    Sandborn, W.J.3
  • 65
    • 80855128813 scopus 로고    scopus 로고
    • Combination of genetic and quantitative serological immune markers are associated with complicated Crohn's disease behavior
    • Published Online First: 9 March doi:10.1002/ibd.21661
    • Lichtenstein GR, Targan SR, Dubinsky MC, et al. Combination of genetic and quantitative serological immune markers are associated with complicated Crohn's disease behavior. Inflamm Bowel Dis. Published Online First: 9 March 2011. doi:10.1002/ibd.21661.
    • (2011) Inflamm Bowel Dis
    • Lichtenstein, G.R.1    Targan, S.R.2    Dubinsky, M.C.3
  • 66
    • 0036120291 scopus 로고    scopus 로고
    • Long term outcome of patients with active Crohn's disease exhibiting extensive and deep ulcerations at colonoscopy
    • DOI 10.1016/S0002-9270(02)03970-9, PII S0002927002039709
    • Allez M, Lemann M, Bonnet J, et al. Long term outcome of patients with active Crohn's disease exhibiting extensive and deep ulcerations at colonoscopy. Am J Gastroenterol 2002;97:947-53. (Pubitemid 34408253)
    • (2002) American Journal of Gastroenterology , vol.97 , Issue.4 , pp. 947-953
    • Allez, M.1    Lemann, M.2    Bonnet, J.3    Cattan, P.4    Jian, R.5    Modigliani, R.6
  • 67
    • 34547503869 scopus 로고    scopus 로고
    • Mucosal Healing in Inflammatory Bowel Disease: Results From a Norwegian Population-Based Cohort
    • DOI 10.1053/j.gastro.2007.05.051, PII S001650850701102X
    • Froslie KF, Jahnsen J, Moum BA, et al. Mucosal healing in inflammatory bowel disease: results from a Norwegian population-based cohort. Gastroenterology 2007;133:412-22. (Pubitemid 47187355)
    • (2007) Gastroenterology , vol.133 , Issue.2 , pp. 412-422
    • Froslie, K.F.1    Jahnsen, J.2    Moum, B.A.3    Vatn, M.H.4
  • 68
    • 70350172248 scopus 로고    scopus 로고
    • Mucosal healing predicts long-term outcome of maintenance therapy with infliximab in Crohn's disease
    • Schnitzler F, Fidder H, Ferrante M, et al. Mucosal healing predicts long-term outcome of maintenance therapy with infliximab in Crohn's disease. Inflamm Bowel Dis 2009;15:1295-301.
    • (2009) Inflamm Bowel Dis , vol.15 , pp. 1295-1301
    • Schnitzler, F.1    Fidder, H.2    Ferrante, M.3
  • 69
    • 63849101007 scopus 로고    scopus 로고
    • Long-term outcome of treatment with infliximab in 614 patients with Crohn's disease: Results from a single-centre cohort
    • Schnitzler F, Fidder H, Ferrante M, et al. Long-term outcome of treatment with infliximab in 614 patients with Crohn's disease: results from a single-centre cohort. Gut 2009;58:492-500.
    • (2009) Gut , vol.58 , pp. 492-500
    • Schnitzler, F.1    Fidder, H.2    Ferrante, M.3
  • 70
    • 70350513112 scopus 로고    scopus 로고
    • Adverse events associated with common therapy regimens for moderate-to-severe Crohn's disease
    • Marehbian J, Arrighi HM, Hass S, et al. Adverse events associated with common therapy regimens for moderate-to-severe Crohn's disease. Am J Gastroenterol 2009;104:2524-33.
    • (2009) Am J Gastroenterol , vol.104 , pp. 2524-2533
    • Marehbian, J.1    Arrighi, H.M.2    Hass, S.3
  • 74
    • 77956526755 scopus 로고    scopus 로고
    • Risk factors for serious infections in patients receiving infliximab and other Crohn's disease therapies: TREAT Registry data
    • Presented at
    • Lichtenstein GR, Cohen RD, Feagan BG, et al. Risk factors for serious infections in patients receiving infliximab and other Crohn's disease therapies: TREAT Registry data. Presented at Digestive Disease Week, 1-5 May 2010, New Orleans.
    • Digestive Disease Week, 1-5 May 2010, New Orleans
    • Lichtenstein, G.R.1    Cohen, R.D.2    Feagan, B.G.3
  • 75
    • 73949147970 scopus 로고    scopus 로고
    • Overall and cause-specific mortality in Crohn's disease: A meta-analysis of population-based studies
    • Duricova D, Pedersen N, Elkjaer M, et al. Overall and cause-specific mortality in Crohn's disease: a meta-analysis of population-based studies. Inflamm Bowel Dis 2010;16:347-53.
    • (2010) Inflamm Bowel Dis , vol.16 , pp. 347-353
    • Duricova, D.1    Pedersen, N.2    Elkjaer, M.3
  • 76
    • 70349314937 scopus 로고    scopus 로고
    • Inflammatory bowel disease and lymphoproliferative disorders: The dust is starting to settle
    • Sokol H, Beaugerie L. Inflammatory bowel disease and lymphoproliferative disorders: the dust is starting to settle. Gut 2009;58:1427-36.
    • (2009) Gut , vol.58 , pp. 1427-1436
    • Sokol, H.1    Beaugerie, L.2
  • 77
    • 70449100743 scopus 로고    scopus 로고
    • Lymphoproliferative disorders in patients receiving thiopurines for inflammatory bowel disease: A prospective observational cohort study
    • Beaugerie L, Brousse N, Bouvier AM, et al. Lymphoproliferative disorders in patients receiving thiopurines for inflammatory bowel disease: a prospective observational cohort study. Lancet 2009;374:1617-25.
    • (2009) Lancet , vol.374 , pp. 1617-1625
    • Beaugerie, L.1    Brousse, N.2    Bouvier, A.M.3
  • 78
    • 67949112671 scopus 로고    scopus 로고
    • Risk of lymphoma associated with combination anti-tumor necrosis factor and immunomodulator therapy for the treatment of Crohn's disease: A meta-analysis
    • Siegel CA, Marden SM, Persing SM, et al. Risk of lymphoma associated with combination anti-tumor necrosis factor and immunomodulator therapy for the treatment of Crohn's disease: a meta-analysis. Clin Gastroenterol Hepatol 2009;7:874-81.
    • (2009) Clin Gastroenterol Hepatol , vol.7 , pp. 874-881
    • Siegel, C.A.1    Marden, S.M.2    Persing, S.M.3
  • 79
    • 78650239266 scopus 로고    scopus 로고
    • A systematic review of factors that contribute to hepatosplenic T-cell lymphoma in patients with inflammatory bowel disease
    • Kotlyar DS, Osterman MT, Diamond RH, et al. A systematic review of factors that contribute to hepatosplenic T-cell lymphoma in patients with inflammatory bowel disease. Clin Gastroenterol Hepatol 2011;9:36-41.
    • (2011) Clin Gastroenterol Hepatol , vol.9 , pp. 36-41
    • Kotlyar, D.S.1    Osterman, M.T.2    Diamond, R.H.3
  • 80
    • 17444386376 scopus 로고    scopus 로고
    • Unemployment and disability in patients with moderately to severely active Crohn's disease
    • DOI 10.1097/01.mcg.0000159220.70290.41
    • Feagan BG, Bala M, Yan S, et al. Unemployment and disability in patients with moderately to severely active Crohn's disease. J Clin Gastroenterol 2005;39:390-5. (Pubitemid 40548076)
    • (2005) Journal of Clinical Gastroenterology , vol.39 , Issue.5 , pp. 390-395
    • Feagan, B.G.1    Bala, M.2    Yan, S.3    Olson, A.4    Hanauer, S.5
  • 82
    • 57249103566 scopus 로고    scopus 로고
    • Direct health care costs of Crohn's disease and ulcerative colitis in US children and adults
    • Kappelman MD, Rifas-Shiman SL, Porter CQ, et al. Direct health care costs of Crohn's disease and ulcerative colitis in US children and adults. Gastroenterology 2008;135:1907-13.
    • (2008) Gastroenterology , vol.135 , pp. 1907-1913
    • Kappelman, M.D.1    Rifas-Shiman, S.L.2    Porter, C.Q.3
  • 83
    • 70450215225 scopus 로고    scopus 로고
    • Treatment of very early rheumatoid arthritis with symptomatic therapy, disease-modifying antirheumatic drugs, or biologic agents: A cost-effectiveness analysis
    • Finckh A, Bansback N, Marra CA, et al. Treatment of very early rheumatoid arthritis with symptomatic therapy, disease-modifying antirheumatic drugs, or biologic agents: a cost-effectiveness analysis. Ann Intern Med 2009;151:612-21.
    • (2009) Ann Intern Med , vol.151 , pp. 612-621
    • Finckh, A.1    Bansback, N.2    Marra, C.A.3


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