Caveolin-1 promotes pancreatic cancer cell differentiation and restores membranous E-cadherin via suppression of the epithelial-mesenchymal transition

Cell Cycle

Volumn 10, Issue 21, 2011, Pages 3692-3700

  Salem, Ahmed F ^a,c   Bonuccelli, Gloria ^a   Bevilacqua, Generoso ^b   Arafat, Hwyda ^d   Pestell, Richard G ^a   Sotgia, Federica ^a   Lisanti, Michael P ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

^c UNIVERSITY OF PISA   (Italy)

^d NATIONAL ORGANIZATION FOR DRUG CONTROL AND RESEARCH NODCAR   (Egypt)

Author keywords

Caveolae; Caveolin 1; Cell differentiation; Chemoresistance; E cadherin; Epithelial mesenchymal transition; Pancreatic cancer

Indexed keywords

BETA CATENIN; CAVEOLIN 1; DOXORUBICIN; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; SMAD PROTEIN; TRANSCRIPTION FACTOR SNAIL; TRANSFORMING GROWTH FACTOR BETA; UVOMORULIN;

ANIMAL TISSUE; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CANCER INHIBITION; CANCER RESISTANCE; CELL CONTACT; CELL DIFFERENTIATION; CELL INVASION; CELL MIGRATION; CONTROLLED STUDY; ENZYME ACTIVATION; EPITHELIAL MESENCHYMAL TRANSITION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PANCREAS CANCER; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN FUNCTION; RECEPTOR DOWN REGULATION; SIGNAL TRANSDUCTION; TUMOR XENOGRAFT;

GASTROPODA;

EID: 80655123603     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.10.21.17895     Document Type: Article

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