An extracellular signal-regulated kinase 2 survival pathway mediates resistance of human mesothelioma cells to asbestos-induced injury

American Journal of Respiratory Cell and Molecular Biology

Volumn 45, Issue 5, 2011, Pages 906-914

  Shukla, Arti ^a   Barrett, Trisha F ^a   MacPherson, Maximilian B ^a   Hillegass, Jedd M ^a   Fukagawa, Naomi K ^a   Swain, William A ^b   O'Byrne, Kenneth J ^c   Testa, Joseph R ^d   Pass, Harvey I ^e   Faux, Stephen P ^b   Mossman, Brooke T ^a  

^a UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF LEICESTER   (United Kingdom)

^c ST JAMES S HOSPITAL   (Ireland)

^d FOX CHASE CANCER CENTER   (United States)

^e NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Asbestos; Epidermal growth factor receptor; Mesothelioma; Protein kinase B AKT; Toxicity

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; CROCIDOLITE; EPIDERMAL GROWTH FACTOR RECEPTOR; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SMALL INTERFERING RNA;

ARTICLE; CANCER CELL CULTURE; CARCINOGENESIS; CELL SURVIVAL; CELL TRANSFORMATION; CELL VIABILITY; CONCENTRATION RESPONSE; CYTOTOXICITY; HUMAN; HUMAN CELL; MALIGNANT MESOTHELIOMA; MESOTHELIOMA CELL; MESOTHELIUM CELL; PROTEIN PHOSPHORYLATION; SIMIAN VIRUS 40; TRANSIENT TRANSFECTION; TUMOR CELL;

ASBESTOS, CROCIDOLITE; CELL LINE; CELL SURVIVAL; ENZYME INHIBITORS; GENE EXPRESSION; HUMANS; MAP KINASE KINASE 1; MAP KINASE KINASE 2; MESOTHELIOMA; MITOGEN-ACTIVATED PROTEIN KINASE 1; PLEURAL NEOPLASMS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

MAMMALIA; SIMIAN VIRUS 40;

EID: 80555157648     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.2010-0282OC     Document Type: Article

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