Retinoic acid drives aryl hydrocarbon receptor expression and is instrumental to dioxin-induced toxicity during palate development

Environmental Health Perspectives

Volumn 119, Issue 11, 2011, Pages 1590-1595

  Jacobs, Hugues ^a   Dennefeld, Christine ^a   Féret, Betty ^a   Viluksela, Matti ^b   Håkansson, Helen ^c   Mark, Manuel ^a,d   Ghyselinck, Norbert B ^a  

^a UNIVERSITÉ DE STRASBOURG   (France)

^b NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^c KAROLINSKA INSTITUTE   (Sweden)

^d UNIVERSITY HOSPITAL OF STRASBOURG   (France)

Author keywords

2,3,7,8 tetrachlorodibenzo p dioxin tcdd; Ahr; Cleft; Mesenchyme; Mouse; Nasal epithelium; Rar; Retinaldehyde dehydrogenase (raldh); Teratogenesis

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; AROMATIC HYDROCARBON RECEPTOR; LACTATE DEHYDROGENASE; RETINOIC ACID; RETINOIC ACID RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CLEFT PALATE; CONTROLLED STUDY; EMBRYO DEVELOPMENT; ENVIRONMENTAL EXPOSURE; GENE FUNCTION; GENE LOCATION; GENETIC CONSERVATION; GESTATIONAL AGE; MARKER GENE; MUTATIONAL ANALYSIS; NONHUMAN; NOSE MUCOSA; NULL ALLELE; PALATE DEVELOPMENT; PALATE MALFORMATION; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; RALDH3 GENE; RARALPHA GENE; RARGAMMA GENE; REPORTER GENE; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

ANIMALS; CLEFT PALATE; MESODERM; MICE; MICE, TRANSGENIC; MODELS, ANIMAL; PALATE; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, ARYL HYDROCARBON; RECEPTORS, RETINOIC ACID; RETINAL DEHYDROGENASE; TETRACHLORODIBENZODIOXIN; TRETINOIN;

ATRA; MUS; VERTEBRATA;

EID: 80555146654     PISSN: 00916765     EISSN: 15529924     Source Type: Journal    
DOI: 10.1289/ehp.1003075     Document Type: Article

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