Development of an analytical strategy based on liquid chromatography-high resolution mass spectrometry for measuring perfluorinated compounds in human breast milk: Application to the generation of preliminary data regarding perinatal exposure in France

Chemosphere

Volumn 85, Issue 3, 2011, Pages 473-480

  Kadar, Hanane ^a   Veyrand, Bruno ^a   Barbarossa, Andrea ^d   Pagliuca, Giampiero ^d   Legrand, Arnaud ^c   Bosher, Cécile ^c   Boquien, Clair Yves ^b,e,f   Durand, Sophie ^a   Monteau, Fabrice ^a   Antignac, Jean Philippe ^a,b   Le Bizec, Bruno ^a  

^a Waters Corporation   (France)

^b Universite de Nantes   (France)

^c Hopital Mere Enfant CHU de Nantes   (France)

^d UNIVERSITY OF BOLOGNA   (Italy)

^e CEMAGREF   (France)

^f Laboratoire d'Acoustique Environnementale)   (France)

Author keywords

Breast milk; High resolution mass spectrometry; Perfluorinated compounds; Perinatal exposure

Indexed keywords

ENDOCRINE DISRUPTERS; LIQUIDS; MASS SPECTROMETRY;

BREAST MILK; ENDOCRINE DISRUPTING PROPERTIES; HIGH RESOLUTION MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY COUPLED TO TANDEM MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY-HIGH RESOLUTION MASS SPECTROMETRIES; PERFLUORINATED COMPOUND (PFCS); PERFLUORINATED COMPOUNDS; PERINATAL EXPOSURE;

HIGH PRESSURE LIQUID CHROMATOGRAPHY;

PERFLUORO BUTANOIC ACID; PERFLUORO COMPOUND; PERFLUORO DECANOIC ACID; PERFLUORO DODECANOIC ACID; PERFLUORO HEPTANOIC ACID; PERFLUORO HEXANOIC ACID; PERFLUORO NONANOIC ACID; PERFLUORO OCTANOIC ACID; PERFLUORO PENTANOIC ACID; PERFLUORO UNDECANOIC ACID; PERFLUORO [1,2 13 C 2]DECANOIC ACID; PERFLUORO [1,2 13 C 2]DODECANOIC ACID; PERFLUORO [1,2,3,4 13 C 4] BUTANOIC ACID; PERFLUORO [1,2,3,4 13 C 4]OCTANOIC ACID; PERFLUORO [1,2,4,5,6,7 13 C 2]UNDECANOIC ACID; PERFLUORO [13 C 9]NONANOIC ACID; PERFLUOROOCTANESULFONATE POTASSIUM; POTASSIUM PERFLUORO 1 BUTANESULFONATE; POTASSIUM PERFLUORO 1 HEPTANESULFONATE; POTASSIUM PERFLUORO 1 HEXANESULFONATE; SODIUM PERFLUORO 1 OCTANESULFINATE ACID; SODIUM PERFLUORO 1 [1,2,3,4 13 C 4] OCTANESULFINATE; SODIUM PERFLUORO 1 [1,2,3,4 13 C 4]OCTANESULFONATE; SODIUM PERFLUORO 1 [18 O 2]HEXANESULFONATE; UNCLASSIFIED DRUG;

ENDOCRINE DISRUPTOR; HEALTH RISK; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MILK; ORGANIC POLLUTANT; POLLUTION EXPOSURE; POLLUTION MONITORING; PUBLIC HEALTH;

ARTICLE; BREAST MILK; FEMALE; FRANCE; HALOGENATION; HUMAN; IONIZATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PERINATAL PERIOD;

EUROPE;

EID: 80555131181     PISSN: 00456535     EISSN: 18791298     Source Type: Journal    
DOI: 10.1016/j.chemosphere.2011.07.077     Document Type: Article

References (42)

1. 3M, 2003. Perfluorooctanoic acid, physicochemicals properties and environmental fate.
2. Abbott B.D., Wolf C.J., Das K.P., Zehr R.D., Schmid J.E., Lindstrom A.B., Strynar M.J., Lau C. Developmental toxicity of perfluorooctane sulfonate (PFOS) is not dependent on expression of peroxisome proliferator activated receptor-alpha (PPAR[alpha]) in the mouse. Reprod. Toxicol. 2009, 27:258-265.
3. Apelberg B.J., Goldman L.R., Calafat A.M., Herbstman J.B., Kuklenyik Z., Heidler J., Needham L.L., Halden R.U., Witter F.R. Determinants of fetal exposure to polyfluoroalkyl compounds in Baltimore, Maryland. Environ. Sci. Technol. 2007, 41:3891-3897.
4. Benskin M.S., Bataineh M., Martin J.W. Simultaneous characterization of perfluoroalkyl carboxylate, sulfonate, and sulfonamide isomers by LC-MS. Anal. Chem. 2007, 79:6455-6464.
5. Berger U., Haukås M. Validation of a screening method based on liquid chromatography coupled to high-resolution mass spectrometry for analysis of perfluoroalkylated substances in biota. J. Chromatogr. A 2005, 1081:210-217.
6. Berger U., Langlois I., Oehme M., Kallenborn R. Comparison of three types of mass spectrometers for high performance liquid chromatography/mass spectrometry analysis of perfluoroalkylated substances and flurotelomers alcohols. Eur. J. MassSpectrom 2004, 10:579-588.
7. Bernsmann T., Fürst P. Determination of perfluorinated compounds in human milk. Organohalogen Compd. 2008, 70:718-721.
8. Bets K.S. What is the evidence telling us?. Environ. Health Perspect. 2007, 115:250-256.
9. Borg D., Bogdanska J., Sundström M., Nobel S., Håkansson H., Bergman Å., DePierre J.W., Halldin K., Bergström U. Tissue distribution of 35S-labelled perfluorooctane sulfonate (PFOS) in C57Bl/6 mice following late gestational exposure. Reprod. Toxicol. 2010, 30:558-565.
10. Chan E., Sandhu M., Benskin J.P., Ralitsch M., Thibault N., Birkholz D., Martin J.W. Endogenous high-performance liquid chromatography/tandem mass spectrometry interferences and the case of perfluorohexane sulfonate (PFHxS) in human serum; are we overestimating exposure. Rapid Commun. Mass Spectrom. 2009, 23:1405-1410.
11. Fei C., McLaughlin J.K., Lipworth L., Olsen J. Maternal levels of perfluorinated chemicals and subfecundity. Human Reprod. 2009, 24:1200-1205.
12. Fromme H., Albrecht M., Angerer J., Drexler H., Gruber L., Schlummer M., Parlar H., Körner W., Wanner A., Heitmann D., Roscher E., Bolte G. Integrated Exposure Assessment Survey (INES): Exposure to persistent and bioaccumulative chemicals in Bavaria, Germany. Int. J. Hyg. Environ. Health 2007, 210:345-349.
13. Fromme H., Mosch C., Morovitz M., Alba-Alejandre I., Boehmer S., Kiranoglu M., Faber F., Hannibal I., Genzel-Boroviczény O., Koletzko B., Volkel W. Pre- and postnatal exposure to perfluorinated compounds (PFCs). Environ. Sci. Technol. 2010, 44:7123-7129.
14. Giesy J.P., Kannan K. Global distribution of perfluorooctane sulfonate in wildlife. Environ. Sci. Technol. 2001, 35:1339-1342.
15. Hansen K.J., Johnson H.O., Eldridge J.S., Butenhoff J.L., Dick L.A. Quantitative Characterization of trace levels of PFOS and PFOA in the Tennessee river. Environ. Sci. Technol. 2002, 36:1681-1685.
16. Hölzer J., Göen T., Rauchfuss K., Kraft M., Angerer J., Kleeschulte P., Wilhelm M. One-year follow-up of perfluorinated compounds in plasma of German residents from Arnsberg formerly exposed to PFOA-contaminated drinking water. Int. J. Hyg. Environ. Health 2009, 212:499-504.
17. Inoue K., Okada F., Ito R., Kato S., Sasaki S., Nakajima S., Uno A., Saijo Y., Sata F., Yoshimura Y., Kishi R., Nakazawa H. Perfluorooctane sulfonate (PFOS) and related perfluorinated compounds in human maternal and cord blood samples: assessment of PFOS exposure in a susceptible population during pregnancy. Environ. Health Perspect. 2004, 112:1204-1216.
18. Kärrman, A., Ericson, I., Van Bavel, B., Lindstrom, G. Analysis and occurence of perfluorinated chemicals in breast milk and serum from swedish Women, 1996-2005, Report 2006.
19. Kärrman A., Ericson I., Van Bavel B., Darnerud P.O., Aune M., Glynn A., Lignell S., Lindström G. Exposure of perfluorinated chemicals through lactation: Llevels of matched human milk and serum and a temporal trend, 1996-2004, in Sweden. Environ. Health Perspect. 2007, 115:226-230.
20. Kissa, E., 2001. Structure of fluorinated surfactants. Fluorinated Surfactants and Repellents, second ed. pp. 1-21.
21. Kuklenyik Z., Reich J.A., Tully J.S., Needham L.L., Calafat A.M. Automated solid-phase extraction and measurement of perfluorinated organic acids and amides in human serum and milk. Environ. Sci. Technol. 2004, 38:3698-3704.
22. Liao C., Wang T., Cui L., Zhou Q., Duan S., Jiang G. Changes in synaptic transmission, calcium current, and neurite growth by perfluorinated compounds are dependent on the chain length and functional group. Environ. Sci. Technol. 2009, 43:2099-2104.
23. Liu C., Du Y., Zhou B. Evaluation of estrogenic activities and mechanism of action of perfluorinated chemicals determined by vitellogenin induction in primary cultured tilapia hepatocytes. Aquat. Toxicol. 2007, 85:267-277.
24. Liu J., Li J., Zhao Y., Wang Y., Zhang L., Wu Y. The occurrence of perfluorinated alkyl compounds in human milk from different regions of China. Environ. Int. 2010, 36:433-438.
25. Llorca M., Farré M., Picó Y., Teijón M.L., Álvarez J.G., Barceló D. Infant exposure of perfluorinated compounds: Levels in breast milk and commercial baby food. Environ. Int. 2010, 36:584-592.
26. Luebker D.J., Case M.T., York R.G., Moore J.A., Hansen K.J., Butenhoff J.L. Two-generation reproduction and cross-foster studies of perfluorooctanesulfonate (PFOS) in rats. Toxicology 2005, 215:126-148.
27. Mosch C., Kiranoglu M., Fromme H., Völkel W. Simultaneous quantitation of perfluoroalkyl acids in human serum and breast milk using on-line sample preparation by HPLC column switching coupled to ESI-MS/MS. J. Chrom. B 2010, 878:2652-2658.
28. Nakata A., Katsumata T., Iwasaki Y., Ito R., Saito K., Izumi S., Makino T., Kishi R., Nakazawa H. Measurement of perfluorinated compounds in human milk and house dust. Organohalogen Compd. 2007, 69:2844-2846.
29. OCDE (Organisation of Economic Co-operation and Development), 2002. Hazard assessment of perfluorooctane sulfonate (PFOS) and its salts.
30. Prevedouros K., Cousins I.T., Buck R.C., Korzeniowski S.H. Sources, fate and transport of perfluorocarboxylates. Environ. Sci. Technol. 2005, 40:32-44.
31. Roosens L., D'Hollander W., Bervoets L., Reynders H., Van Campenhout K., Cornelis C., Van Den Heuvel R., Koppen G., Covaci A. Brominated flame retardants and perfluorinated chemicals, two groups of persistent contaminants in Belgian human blood and milk. Environ. Pollut. 2010, 158:2546-2552.
32. Rylander, C., Brustad, M., Falk H., M. Sandanger, T., 2009. Dietary predictors and plasma concentrations of perfluorinated compounds in a coastal population from Northern Norway 2009.
33. Simcik M.F., Dorweiler K.J. Ratio of perfluorochemical concentrations as a tracer of atmospheric deposition to surface waters. Environ. Sci. Technol 2005, 39:8678-8683.
34. So M.K., Yamashita N., Taniyasu S., Jiang Q., Giesy J.P., Chen K., Lam P.K.S. Health risks in infants associated with exposure to perfluorinated compounds in human breast milk from zhoushan. China Environ. Sci. Technol. 2006, 40:2924-2929.
35. Taniyasu S., Kannan K., Horii Y., Hanari N., Yamashita N. A Survey of perfluorooctane sulfonate and related perfluorinated organic compounds in water, fish, birds, and humans from Japan. Environ. Sci. Technol 2003, 37:2634-2639.
36. Tao L., Kannan K., Wong C.M., Arcaro K.F., Butenhoff J.L. Perfluorinated compounds in human milk from massachusetts. USA Environ. Sci. Technol. 2008, 42:3096-3101.
37. Tao L., Ma J., Kunisue T., Libelo E.L., Tanabe S., Kannan K. Perfluorinated compounds in human breast milk from several Asian countries, and in infant formula and dairy milk from the United States. Environ. Sci. Technol. 2008, 42:8597-8602.
38. US EPA (Environment Protection Agency), 2005. Draft risk assessment of the potential human health effects associated with exposure to perfluorooctanoic acid and its salts, United States.
39. Völkel W., Genzel-Boroviczény O., Demmelmair H., Gebauer C., Koletzko B., Twardella D., Raab U., Fromme H. Perfluorooctane sulphonate (PFOS) and perfluorooctanoic acid (PFOA) in human breast milk: results of a pilot study. Int. J. Hyg. Environ. Health 2008, 211:440-446.
40. Von Ehrenstein O.S., Fenton S.E., Kato K., Kuklenyik Z., Calafat A.M., Hines E.P. Polyfluoroalkyl chemicals in the serum and milk of breastfeeding women. Reprod. Toxicol. 2009, 27:239-245.
41. Wang T., Wang Y., Liao C., Cai Y., Jiang G. Perspectives on the inclusion of perfluorooctane sulfonate into the stockholm convention on persistent organic pollutants1. Environ. Sci. Technol. 2009, 43:5171-5175.
42. Wang F., Liu W., Jin Y., Dai J., Yu W., Liu X., Liu L. Transcriptional effects of prenatal and neonatal exposure to PFOS in developing rat brain. Environ. Sci. Technol. 2010, 44:1847-1853.