Brominated flame retardants and perfluorinated chemicals, two groups of persistent contaminants in Belgian human blood and milk

Environmental Pollution

Volumn 158, Issue 8, 2010, Pages 2546-2552

  Roosens, Laurence ^a   D'Hollander, Wendy ^a   Bervoets, Lieven ^a   Reynders, Hans ^b   Van Campenhout, Karen ^b   Cornelis, Christa ^c   Van Den Heuvel, Rosette ^c   Koppen, Gudrun ^c   Covaci, Adrian ^a  

^a UNIVERSITY OF ANTWERP   (Belgium)

^b Flemish Government   (Belgium)

^c FLEMISH INSTITUTE FOR TECHNOLOGICAL RESEARCH VITO   (Belgium)

Author keywords

Adolescent; Adult; Belgium; BFRs; Biomonitoring; Exposure; Human blood; Human milk; Newborn; PFCs

Indexed keywords

ADOLESCENT; ADULT; BELGIUM; BFRS; BIOMONITORING; EXPOSURE; HUMAN BLOODS; HUMAN MILK; NEWBORN; PFCS;

ACIDS; ETHERS; FIRE FIGHTING EQUIPMENT; FLAME RETARDANTS;

BLOOD;

FLAME RETARDANT; HEXABROMOCYCLODODECANE; PERFLUORO COMPOUND; PERFLUOROOCTANESULFONIC ACID; PERFLUOROOCTANOIC ACID; POLYBROMINATED DIPHENYL ETHER; ALKANESULFONIC ACID; BROMINATED HYDROCARBON; DIPHENYL ETHER DERIVATIVE; FLUORINATED HYDROCARBON; FLUOROCARBON; OCTANOIC ACID DERIVATIVE; POLLUTANT;

BIOMONITORING; BLOOD; BROMINE; ESTIMATION METHOD; MILK; POLLUTION EXPOSURE;

ADOLESCENT; ADULT; AGE DISTRIBUTION; AGED; ARTICLE; BELGIUM; BIOLOGICAL MONITORING; BLOOD; BLOOD SAMPLING; CALIBRATION; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; FEMALE; FOOD CONTAMINATION; HUMAN; MILK; NEWBORN; PERINATAL PERIOD; PLACENTAL TRANSFER; PRENATAL EXPOSURE; QUALITY CONTROL; SERUM; UMBILICAL CORD BLOOD; ANALYSIS; BREAST MILK; ENVIRONMENTAL MONITORING; FETUS BLOOD; MALE; METABOLISM; MIDDLE AGED; POLLUTANT; POLLUTION; STATISTICS AND NUMERICAL DATA; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; ALKANESULFONIC ACIDS; BELGIUM; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL MONITORING; ENVIRONMENTAL POLLUTANTS; ENVIRONMENTAL POLLUTION; FEMALE; FETAL BLOOD; FLAME RETARDANTS; FLUOROCARBONS; HALOGENATED DIPHENYL ETHERS; HUMANS; HYDROCARBONS, BROMINATED; HYDROCARBONS, FLUORINATED; INFANT, NEWBORN; MALE; MIDDLE AGED; MILK, HUMAN; OCTANOIC ACIDS; YOUNG ADULT; CAPRYLATES;

BELGIUM;

EID: 77958171830     PISSN: 02697491     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.envpol.2010.05.022     Document Type: Article

References (65)

1. 3M Environmental and Health Assessment of Perfluoroctane Sulfonic Acid and Its Salts AR226-1486 2003 U.S. Environmental Protection Agency Public Docket
2. M. Alaee, P. Arias, A. Sjodin, and A. Bergman An overview of commercially used brominated flame retardants, their applications, their use patterns in different countries-regions and possible modes of release Environment International 29 2003 683 689
3. J.P. Antignac, R. Cariou, D. Zalko, A. Berrebi, J.P. Cravedi, D. Maume, P. Marchand, F. Monteau, A. Riu, F. Andre, and B. Le Bizec Exposure assessment of French women and their newborn to brominated flame retardants: determination of tri- to deca- polybrominated diphenyl ethers (PBDEs) in maternal adipose tissue, serum, breast milk and cord serum Environmental Pollution 157 2009 164 173
4. B.J. Apelberg, L.R. Goldman, A.M. Calafat, J.B. Herbstman, Z. Kuklenyik, J. Heidler, L.L. Needham, R.U. Halden, and F.R. Writter Determinants of fetal exposure to polyfluoroalkyl compounds in Baltimore, Maryland Environmental Science and Technology 41 2007 3891 3897
5. T. Bernsmann, and P. Fürst Determination of perfluorinated compounds in human milk Organohalogen Compounds 70 2008 718 721
6. K. Betts New thinking on flame retardants Environmental Health Perspectives 116 2008 210 213
7. A.M. Calafat, L.L. Needham, Z. Kuklenyik, J.A. Reidy, J.S. Tully, A. Aguilar-Villalobos, and L.P. Naeher Perfluorinated chemicals in selected residents of the American continent Chemosphere 63 2006 490 496
8. A.M. Calafat, Z. Kuklenyik, J.A. Reidy, S.P. Caudill, J.S. Tully, and L.L. Needham Serum concentrations of 11 polyfluoroalkyl compounds in the U.S. population: data from the National Health and Nutrition Examination Survey (NHANES) 1999-2000 Environmental Science and Technology 41 2007 2237 2242
9. D. Carrizo, and J. Grimalt Influence of breastfeeding in the accumulation of polybrominated diphenyl ethers during the first years of child growth Environmental Science and Technology 41 2007 4907 4912
10. A. Colles, G. Koppen, V. Hanot, V. Nelen, M.C. Dewolf, E. Noël, R. Malisch, A. Kotz, K. Kypke, P. Biot, C. Vinkx, and G. Schoeters Fourth WHO-coordinated survey of human milk for persistent organic pollutants (POPs): Belgian results Chemosphere 73 2008 907 914
11. A. Covaci, S. Voorspoels, L. Roosens, W. Jacobs, R. Blust, and H. Neels Polybrominated diphenyl ethers (PBDEs) and polychlorinated biphenyls (PCBs) in human liver and adipose tissue samples from Belgium Chemosphere 73 2008 170 175
12. A. Covaci, L. Roosens, A.C. Dirtu, N. Waegeneers, I. Van Overmeire, H. Neels, and L. Goeyens Brominated flame retardants in Belgian home-produced eggs: levels and contamination sources Science of the Total Environment 407 2009 4387 4396
13. A. Covaci, and S. Voorspoels Optimization of the determination of polybrominated diphenyl ethers in human serum using solid-phase extraction and gas chromatography-electron capture negative ionization mass spectrometry Journal of Chromatography B 827 2005 216 223
14. T. Dauwe, K. Van de Vijver, W. De Coen, and M. Eens PFOS levels in the blood and liver of a small insectivorous songbird near a fluorochemical plant Environment International 33 2007 357 361
15. Directive 2003/11/EC of the European Parliament and of the Council of 6 Feburary 2003 amending for the 24th time Council directive 76/769/EEC relating to restrictions on the marketing and use of certain dangerous substances and preparations (pentabromodiphenyl ether and octabromodiphenyl ether) Official Journal L 042 15/02/2003
16. Directive 2006/122/EC of the European Parliament relating to Perfluorooctane sulfonate (PFOS), perfluorooctanoic acid (PFOA) and their salts Scientific Opinion of the Panel on Contaminants in the Food chain (Question No EFSA-Q-2004-163).
17. J. Dobbing, and J. Sands Comparative aspects of the brain growth spurt Early Human Development 3 1979 79 83
18. I. Ericson, M. Gomez, M. Nadal, B. van Bavel, G. Lindstorm, and J.L. Domingo Perfluorinated chemicals in blood of residents in Catalonia (Spain) in relation to age and gender: a pilot study Environment International 33 2007 616 623
19. I. Ericson, R. Marti-Cid, M. Nadal, B. van Bavel, G. Lindstrom, and J.L. Domingo Human exposure to perfluorinated chemicals through the diet: intake of perfluorinated compounds in foods from the Catalan (Spain) Market Journal of Agricultural and Food Chemistry 56 2008 1787 1794
20. B. Fangstrom, L. Hovander, A. Bignert, I. Athanassiadis, L. Linderholm, P. Grandjean, P. Weihe, and A. Bergman Concentrations of polybrominated diphenyl ethers, polychlorinated biphenyls, and polychlorobiphenylols in serum from pregnant Faroese women and their children 7 years later Environmental Science and Technology 39 2005 9457 9463
21. M. Frederiksen, K. Vorkamp, M. Thomsen, and L.E. Knudsen Human internal and external exposure to PBDEs - a review of levels and sources International Journal of Hygiene and Environmental Health 212 2009 109 134
22. H. Fromme, M. Schlummer, A. Möller, L. Gruber, G. Wolz, J. Ungewiß, S. Böhmer, W. Dekant, R. Mayer, B. Liebl, and D. Twardella Exposure of an adult population to perfluorinated substances using duplicate diet portions and biomonitoring data Environmental Science and Technology 41 2007 7928 7933
23. H. Fromme, W. Körner, N. Shahin, A. Wanner, M. Albrecht, S. Boehmer, H. Parlar, R. Mayer, B. Liebl, and G. Bolte Human exposure to polybrominated diphenyl ethers (PBDE), as evidenced by data from a duplicate diet study, indoor air, house dust, and biomonitoring in Germany Environment International 35 2009 1125 1135
24. H. Geyer, K. Schramm, P.O. Darnerud, M. Aune, E. Feicht, F. Fried, B. Henkelmann, D. Lenoir, P. Schmid, and T.A. McDonald Terminal elimination half-lives of the brominated flame retardants TBBPA, HBCD, and lower brominated PBDEs in humans Organohalogen Compounds 66 2004 3867 3872
25. I. Glorieux, and J. Minnen Website "Belgisch tijdsbudgetonderzoek" 2008 http://www.time-use.be
26. B. Gomara, L. Herrero, J.J. Ramos, J.R. Mateo, M.A. Fernandez, J.F. Garcia, and M.J. Gonzalez Distribution of polybrominated diphenyl ethers in human umbilical cord serum, paternal serum, maternal serum, placentas, and breast milk from Madrid population, Spain Environmental Science and Technology 41 2007 6961 6968
27. S. Harrad, C.A. de Wit, M.A.E. Abdallah, C. Bergh, J.A. Björklund, A. Covaci, P.O. Darnerud, J. de Boer, M. Diamond, S. Huber, P. Leonards, M. Mandalakis, C. Östman, L.S. Haug, C. Thomsen, and T.F. Webster Indoor contamination with hexabromocyclododecanes, polybrominated diphenyl ethers and perfluoroalkyl compounds: an important exposure pathway for people? Environmental Science and Technology 41 2010 3221 3231
28. M. Hauks, U. Berger, H. Hop, B. Gulliksen, and G.W. Gabrielsen Bioaccumulation of per- and polyfluorinated alkyl substances (PFAS) in selected species from the Barents Sea food web Environmental Pollution 148 2007 360 371
29. J.B. Herbstman, A. Sjödin, B.J. Apelberg, F.R. Witter, D.G. Patterson Jr., R.U. Halden, R.S. Jones, A. Park, Y. Zhang, J. Heidler, L.L. Needham, and L.R. Goldman Determinants of prenatal exposure to polychlorinated biphenyls (PCBs) and polybrominated diphenyl ethers (PBDEs) in an urban population Environmental Health Perspectives 115 2007 1794 1800
30. J. Hölzer, O. Midasch, K. Rauchfuss, M. Kraft, R. Reupert, J. Angerer, P. Kleeschulte, N. Marschall, and M. Wilhelm Biomonitoring of perfluorinated compounds in children and adults exposed to perfluorooctanoate (PFOA)-contaminated drinking water Environmental Health Perspectives 116 2008 651 657
31. Holmström, K.E., Berglund, M., Järnberg, U., 2005. Exposure to perfluorinated acids in 108 Swedish women in relation to methylmercury and fish consumption. Poster ANA003. 9th International Symposium on Fluorinated Alkyl Organics in the Environment, August 2005, Toronto, Canada.
32. K. Inoue, F. Okada, R. Ito, S. Kato, S. Sasaki, S. Nakajima, A. Uno, Y. Saijo, F. Sata, Y. Yoshimura, R. Kishi, and H. Nakazawa Perfluorooctane sulfonate (PFOS) and related perfluorinated compounds in human maternal and cord blood samples: assessment of PFOS exposure in a susceptible population during pregnancy Environmental Health Perspectives 112 2004 1204 1207
33. N. Johansson, H. Viberg, A. Fredriksson, and P. Eriksson Neonatal exposure to deca-brominated diphenyl ether (PBDE 209) causes dose-response changes in spontaneous behaviour and cholinergic susceptibility in adult mice Neurotoxicology 29 2008 911 919
34. K. Kannan, S. Corsolini, J. Falandysz, G. Fillmann, K. Kumar, B.G. Loganathan, M.A. Mohd, J. Oliveiro, N. Van Wouwe, J.H. Yang, and K.M. Aldous Perfluorooctane sulfonate and related fluorochemicals in human blood from several countries Environmental Science and Technology 38 2004 4489 4495
35. A. Kärrman, B. van Bavel, U. Järnberg, L. Hardell, and G. Lindström Perfluorinated chemicals in relation to other persistent organic pollutants in human blood Chemosphere 64 2006 1582 1591
36. A. Kärrman, I. Ericson, B. van Bavel, P.O. Darnerud, M. Aune, A. Glynn, S. Lignell, and G. Lindström Exposure of perfluorinated chemicals through lactation: levels of matched human milk and serum and a temporal trend, 1996-2004, in Sweden Evironmental Health Perspectives 115 2007 226 230
37. K. Kato, A.M. Calafat, L.Y. Wong, A. Wanigatunga, S.P. Caudill, and L.L. Needham Polyfluoroalkyl compounds in pooled sera from children participating in the National Health and Nutrition Examination Survey 2001#2002 Environmental Science and Technology 43 2009 2641 2647
38. Y. Kawashiro, H. Fukata, M. Imori-Inoue, K. Kuboyona, T. Jotaki, H. Takigami, S. Sakai, and C. Mori Perinatal exposure to brominated flame retardants and polychlorinated biphenyls in Japan Endocrine Journal 55 2008 1071 1084
39. B.D. Key, R.D. Howell, and C.S. Criddle Fluorinated organics in the biosphere Environmental Science and Technology 31 1997 2454 2455
40. S. Lignell, M. Aune, P.O. Darnerud, S. Cnattingius, and A. Glynn Persistent organochlorine and organobromine compounds in mother's milk from Sweden1996-2006: compound-specific temporal trends Environmental Research 109 2009 760 767
41. A. Mazdai, N.G. Dodder, M.P. Abernathy, R.A. Hites, and R.M. Bigsby Polybrominated diphenyl ethers in maternal and fetal blood samples Environmental Health Perspectives 111 2003 1249 1252
42. L. Meijer, J. Weiss, M. Van Velzen, A. Brouwer, A. Bergman, and P.J.J. Sauer Serum concentrations of neutral and phenolic organohalogens in pregnant women and some of their infants in the Netherlands Environmental Science and Technology 42 2008 3428 3433
43. O. Midasch, T. Schettgen, and J. Angerera Pilot study on the perfluorooctanesulfonate and perfluorooctanoate exposure of the German general population International Journal of Hygiene and Environmental and Environmental Health 209 2006 489 496
44. O. Midasch, H. Drexler, N. Hart, M.W. Beckmann, and J. Angerer Transplacental exposure of neonates to perfluorooctane sulfonate and perfluorooctanoate: a pilot study International Archives of Occupational and Environmental Health 80 2007 643 648
45. G.W. Olsen, J.M. Burris, D.J. Ehresman, J.W. Froehlich, A.M. Seacat, J.L. Butenhoff, and L.R. Zobel Half-life of serum elimination of perfluorooctanesurfonate, perfluorohexanexulfonate, and perfluorooctanoate in retired fluorochemical production workers Environmental Health Perspectives 115 2007 1298 1305
46. L. Roosens, M.A.E. Abdallah, S. Harrad, H. Neels, and A. Covaci Factors influencing concentrations of polybrominated diphenyl ethers (PBDEs) in students from Antwerp, Belgium Environmental Science and Technology 43 2009 3535 3541
47. L. Roosens, M.A.E. Abdallah, S. Harrad, H. Neels, and A. Covaci Exposure to hexabromocyclododecanes via dust ingestion, but not diet, correlates with concentrations in human serum - preliminary results Environmental Health Perspectives 117 2009 1707 1712
48. L. Roosens, C. Cornelis, W. D'Hollander, L. Bervoets, H. Reynders, K. Van Campenhout, R. Van Den Heuvel, H. Neels, and A. Covaci Exposure of the Flemish population to brominated flame retardants: model and risk assessment Environment International 36 2010 368 376
49. A. Schecter, O. Päpke, K.C. Tung, J. Joseph, T.R. Harris, and J. Dahlgren Polybrominated diphenyl ether flame retardants in the U.S. Population: current levels, temporal trends, and comparison with dioxins, dibenzofurans, and polychlorinated biphenyls Journal of Occupational and Environmental Medicine 47 2005 199 211
50. A. Schecter, T.R. Harris, N. Shah, A. Musumba, and O. Papke Brominated flame retardants in US food Molecular Nutrition and Food Research 52 2008 266 272
51. Z.H. Shi, Y.N. Wu, J.G. Li, Y.F. Zhao, and J.F. Feng Dietary exposure assessment of Chinese adults and nursing infants to tetrabromobisphenol-A and hexabromocyclododecanes: occurrence measurements in foods and human milk Environmental Science and Technology 43 2009 4314 4319
52. M.K. So, N. Yamashita, S. Taniyasu, Q. Jinang, J.P. Giesy, K. Chen, and P.K. Lam Health risks in infants associated with exposure to perfluorinated compounds in human breast milk from Zhoushan, China Environmental Science and Technology 40 2006 720 751
53. H.M. Stapleton, A. Sjodin, R. Jones, S. Niehuser, Y. Zhang, and D.G. Patterson Serum levels of polybrominated diphenyl ethers (PBDEs) in foam recyclers and carpet installers working in the United States Environmental Science and Technology 42 2008 3453 3458
54. Stockholm convention http://chm.pops.int/Convention/Pressrelease/ COP4Geneva9May2009 /tabid/542/ language/en-US/Default.aspx 2009
55. S. Taniyasu, K. Kannan, M. So, A. Gulkowska, E. Sinclair, and T. Okazawa Analysis of fluortelomer alcohols, fluortelomer acids and short- and long- chain perfluorinated acids in water and biota Journal of Chromatography A 1093 2005 89 97
56. L. Tao, K. Kannan, C.H. Wong, K.F. Arcaro, and J.L. Butenhoff Perfluorinated compounds in human milk form Massachusetts, U.S.A. Environmental Science and Technology 42 2008 3096 3101
57. L.M.L. Toms, F. Harden, O. Paepke, P. Hobson, J.J. Ryan, and J.F. Mueller Higher accumulation of polybrominated diphenyl ethers (PBDEs) in infants than in adults Environmental Science and Technology 42 2008 7510 7515
58. L. Toms, A. Sjödin, F. Harden, P. Hobson, R. Jones, E. Edenfield, and J.F. Mueller Serum polybrominated diphenyl ether (PBDE) levels are higher in children (2-5 years of age) than in infants and adults Environmental Health Perspectives 117 2009 1461 1465
59. L.T.M. Van der Ven, T. Van de Kuil, P.E.G. Leonards, W. Slob, H. Lilienthal, S. Litens, M. Herlin, H. Hkansson, R.C. Cantón, M. Van den Berg, T.J. Visser, H. Van Loveren, J.G. Vos, and A.H. Piersma Endocrine effects of hexabromocyclododecane (HBCD) in a one-generation reproduction study in Wistar rats Toxicology Letters 185 2009 51 62
60. R. Vestergren, T. Ian, I.T. Cousins, D. Trudel, M. Wormuth, and M. Scheringer Estimating the contribution of precursor compounds in consumer exposure to PFOS and PFOA Chemosphere 73 2008 1617 1624
61. W. Völkel, O. Genzel-Boroviczeny, H. Demmelmair, C. Gebauer, B. Koletzko, D. Twardella, U. Raab, and H. Fromme Perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) in human breast milk. Results of a pilot study International Journal of Hygiene and Environmental Health 211 2008 440 446
62. R. de Winter-Sorkina, M.I. Bakker, R.A. Baumann, R. Hoogerbrugge, and M.J. Zeilmaker Exposure Assessment of Dutch Nursing Infants to BFRs via Breast Milk 2003 RIVM Bilthoven, the Netherlands
63. L.W.Y. Yeung, M.K. So, G. Jiang, S. Taniyasu, N. Yamashita, M. Song, Y. Wu, J.P. Giesy, K.S. Guruge, and P.K.S. Lam Perfluorooctanesulfonate and related fluorchemicals in human blood samples from China Environmental Science and Technology 40 2006 715 720
64. L. Zhu, B. Ma, and R.A. Hites Brominated flame retardants in serum from the general population in Northern China Environmental Science and Technology 43 2009 6963 6968
65. L. Zhu, B. Ma, Y. Li, Y. Wu, and Y. Gong Distribution of polybrominated diphenyl ethers in breast milk from North China: implication of exposure pathways Chemosphere 74 2009 1429 1434