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Volumn 94, Issue 4, 1996, Pages 817-823

HERG, a primary human ventricular target of the nonsedating antihistamine terfenadine

Author keywords

delayed rectifier; ketoconazole; oocytes; terfenadine

Indexed keywords

ANTIHISTAMINIC AGENT; MEMBRANE PROTEIN; PROTEIN HERG; TERFENADINE; UNCLASSIFIED DRUG;

EID: 0029761822     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.94.4.817     Document Type: Article
Times cited : (279)

References (39)
  • 1
    • 0004322286 scopus 로고
    • IMS America Ltd, Plymouth Meeting, Pa, 1992
    • 1992 National Prescription Audit. IMS America Ltd, Plymouth Meeting, Pa, 1992.
    • (1992) National Prescription Audit
  • 3
    • 0024533132 scopus 로고
    • Cardiotoxic effect with convulsions in terfenadine overdose
    • Abstract
    • Davies AJ, Harinda V, McEwan A, Chose RR. Cardiotoxic effect with convulsions in terfenadine overdose. Br Med J. 1989;298:325. Abstract.
    • (1989) Br Med J. , vol.298 , pp. 325
    • Davies, A.J.1    Harinda, V.2    McEwan, A.3    Chose, R.R.4
  • 7
    • 0027996327 scopus 로고
    • Terfenadine metabolism in human liver: In vitro inhibition by macrolide antibiotics and azole antifungals
    • Jurima-Romet M, Crawford K, Cyr T, Inaba T. Terfenadine metabolism in human liver: in vitro inhibition by macrolide antibiotics and azole antifungals. Drug Metab Dis. 1994;22:849-857.
    • (1994) Drug Metab Dis. , vol.22 , pp. 849-857
    • Jurima-Romet, M.1    Crawford, K.2    Cyr, T.3    Inaba, T.4
  • 8
    • 0028936268 scopus 로고
    • Cardiac electrophysiological actions of the histamine HI-receptor antagonists astemizole and terfenadine compared with chlorpheniramine and pyrilamine
    • Salata JJ, Jurkiewicz NK, Wallace AA, Stupienski RF III, Guinosso PJ Jr, Lynch JJ Jr. Cardiac electrophysiological actions of the histamine HI-receptor antagonists astemizole and terfenadine compared with chlorpheniramine and pyrilamine. Circ Res. 1995;73: 110-119.
    • (1995) Circ Res. , vol.73 , pp. 110-119
    • Salata, J.J.1    Jurkiewicz, N.K.2    Wallace, A.A.3    Stupienski III, R.F.4    Guinosso Jr., P.J.5    Lynch Jr., J.J.6
  • 9
    • 0028233422 scopus 로고
    • A dynamic model of the cardiac ventricular action potential, I: Simulations of ionic currents and concentration changes
    • Luo C, Rudy Y. A dynamic model of the cardiac ventricular action potential, I: simulations of ionic currents and concentration changes. Circ Res. 1994;74:1071-1096.
    • (1994) Circ Res. , vol.74 , pp. 1071-1096
    • Luo, C.1    Rudy, Y.2
  • 10
    • 0026506174 scopus 로고
    • Contribution of delayed rectifier and inward rectifier to repolarization of the action potential: Pharmacologic separation
    • Martin BCL, Chinn K. Contribution of delayed rectifier and inward rectifier to repolarization of the action potential: pharmacologic separation. J Cardiovasc Pharmacol. 1992;19:830-837.
    • (1992) J Cardiovasc Pharmacol , vol.19 , pp. 830-837
    • Bcl, M.1    Chinn, K.2
  • 12
    • 0014438985 scopus 로고
    • Outward membrane currents activated in the plateau range of potentials in cardiac Purkinje fibers
    • Noble D, Tsien RW. Outward membrane currents activated in the plateau range of potentials in cardiac Purkinje fibers. J Physiol (Lond). 1969;200:205-231.
    • (1969) J Physiol (Lond) , vol.200 , pp. 205-231
    • Noble, D.1    Tsien, R.W.2
  • 13
    • 0025351245 scopus 로고
    • + current: Differential sensitivity to block by class III antiarrhythmic agents
    • + current: differential sensitivity to block by class III antiarrhythmic agents. J Gen Physiol. 1990;96:195-215.
    • (1990) J Gen Physiol , vol.96 , pp. 195-215
    • Sanguinetti, M.C.1    Jurkiewicz, N.K.2
  • 14
    • 0025162922 scopus 로고
    • Time-dependent outward current in guinea pig ventricular myocytes: Gating kinetics of the delayed rectifier
    • Balser JR, Bennet PB, Roden DM. Time-dependent outward current in guinea pig ventricular myocytes: gating kinetics of the delayed rectifier. J Gen Physiol. 1990;96:835-863.
    • (1990) J Gen Physiol , vol.96 , pp. 835-863
    • Balser, J.R.1    Bennet, P.B.2    Roden, D.M.3
  • 15
    • 0023513790 scopus 로고
    • An analysis of the delayed outward current in single ventricular cells of the guinea pig
    • Matsuura H, Ehara T, Imoto Y. An analysis of the delayed outward current in single ventricular cells of the guinea pig. Pflugers Arch. 1987;410:596-603.
    • (1987) Pflugers Arch , vol.410 , pp. 596-603
    • Matsuura, H.1    Ehara, T.2    Imoto, Y.3
  • 16
    • 0027376226 scopus 로고
    • + current similar to Kvl.5 cloned channel currents
    • + current similar to Kvl.5 cloned channel currents. Circ Res. 1993;73:1061-1076.
    • (1993) Circ Res , vol.73 , pp. 1061-1076
    • Wang, Z.1    Fermini, B.2    Nattel, S.3
  • 18
    • 0027474601 scopus 로고
    • Mechanisms of the cardiotoxic actions of terfenadine
    • Woosley RL, Chen Y, Frieman JP, Gillis RA. Mechanisms of the cardiotoxic actions of terfenadine. JAMA. 1993;269:1532-1536.
    • (1993) JAMA , vol.269 , pp. 1532-1536
    • Woosley, R.L.1    Chen, Y.2    Frieman, J.P.3    Gillis, R.A.4
  • 19
    • 0028838078 scopus 로고
    • Blockade of multiple human cardiac potassium currents by the antihistamine terfenadine: Possible mechanism for terfenadine-associated cardiotoxicity
    • Crumb WJ, Wible BA, Arnold DJ, Payne JP, Brown AM. Blockade of multiple human cardiac potassium currents by the antihistamine terfenadine: possible mechanism for terfenadine-associated cardiotoxicity. Mol Pharmacol. 1995;47:181-190.
    • (1995) Mol Pharmacol , vol.47 , pp. 181-190
    • Crumb, W.J.1    Wible, B.A.2    Arnold, D.J.3    Payne, J.P.4    Brown, A.M.5
  • 20
    • 0028927451 scopus 로고
    • Regulation of potassium channels by nonsedating antihistamines
    • Berul CI, Morad M, Regulation of potassium channels by nonsedating antihistamines. Circulation. 1995;91:2220-2225.
    • (1995) Circulation , vol.91 , pp. 2220-2225
    • Berul, C.I.1    Morad, M.2
  • 21
    • 0028292927 scopus 로고
    • A family of potassium channel genes related to eag in Drosophila and mammals
    • Warmke JW, Ganetzky B. A family of potassium channel genes related to eag in Drosophila and mammals. Proc Natl Acad Sci USA. 1994;91:3438-3442.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 3438-3442
    • Warmke, J.W.1    Ganetzky, B.2
  • 23
    • 0029007356 scopus 로고
    • HERG, a human inward rectifier in the voltage-gated potassium channel family
    • Trudeau MC, Watmke JW, Ganetzky B, Robertson GA. HERG, a human inward rectifier in the voltage-gated potassium channel family. Science. 1995;269:92-95.
    • (1995) Science , vol.269 , pp. 92-95
    • Trudeau, M.C.1    Watmke, J.W.2    Ganetzky, B.3    Robertson, G.A.4
  • 27
    • 0028855945 scopus 로고
    • A quantitative description of the E-4031-sensitive repolarization current in rabbit ventricular myocytes
    • Clay JR, Ogbaghebriel A, Paquette T, Sasyniuk BI, Shrier A. A quantitative description of the E-4031-sensitive repolarization current in rabbit ventricular myocytes. Biophys J. 1995;69:1830-1837.
    • (1995) Biophys J , vol.69 , pp. 1830-1837
    • Clay, J.R.1    Ogbaghebriel, A.2    Paquette, T.3    Sasyniuk, B.I.4    Shrier, A.5
  • 29
    • 0030058762 scopus 로고    scopus 로고
    • Class III antiarrhythmic drugs block HERG, a human cardiac delayed rectifier K*channel: Open block by methanesulfonanilides
    • Spector PS, Curran ME, Keating MT, Sanguinetti MC. Class III antiarrhythmic drugs block HERG, a human cardiac delayed rectifier K*channel: open block by methanesulfonanilides. Circ Res. 1996; 78:499-503.
    • (1996) Circ Res , vol.78 , pp. 499-503
    • Spector, P.S.1    Curran, M.E.2    Keating, M.T.3    Sanguinetti, M.C.4
  • 30
    • 0028306696 scopus 로고
    • Frequency-dependent effects of E-4031, almokalant, dofetilide and tedismal on action potential duration: No evidence for 'reverse use-dependent' block
    • Ohler A, Amos GJ, Wettwer E, Ravens U. Frequency-dependent effects of E-4031, almokalant, dofetilide and tedismal on action potential duration: no evidence for 'reverse use-dependent' block. Naunyn Schmiedebergs Arch Pharmacol. 1994;349:602-610.
    • (1994) Naunyn Schmiedebergs Arch Pharmacol , vol.349 , pp. 602-610
    • Ohler, A.1    Amos, G.J.2    Wettwer, E.3    Ravens, U.4
  • 31
    • 9544229848 scopus 로고
    • Differences in outward currents of human atrial and ventricular myocytes
    • Abstract
    • Amos GJ, Wettwer E, Li Q, Himmel HM, Ravens U. Differences in outward currents of human atrial and ventricular myocytes. Circulation. 1994;4(suppl I):I-581. Abstract.
    • (1994) Circulation , vol.4 , Issue.SUPPL. I
    • Amos, G.J.1    Wettwer, E.2    Li, Q.3    Himmel, H.M.4    Ravens, U.5
  • 33
    • 0023734276 scopus 로고
    • Cloning of a membrane protein that induces a slow voltage-gated potassium current
    • Takumi T, Ohkubo H, Niakanishi S. Cloning of a membrane protein that induces a slow voltage-gated potassium current. Science. 1988; 242:1042-1045.
    • (1988) Science , vol.242 , pp. 1042-1045
    • Takumi, T.1    Ohkubo, H.2    Niakanishi, S.3
  • 34
    • 0024309922 scopus 로고
    • Molecular cloning and sequence analysis of human genomic DNA encoding a novel membrane protein which exhibits a slowly activating potassium channel activity
    • Murai T, Kakizuka A, Takumi T, Ohkubo H, Nakanishi S. Molecular cloning and sequence analysis of human genomic DNA encoding a novel membrane protein which exhibits a slowly activating potassium channel activity. Biochem Biophys Res Commun. 1989;161: 176-181.
    • (1989) Biochem Biophys Res Commun. , vol.161 , pp. 176-181
    • Murai, T.1    Kakizuka, A.2    Takumi, T.3    Ohkubo, H.4    Nakanishi, S.5
  • 38
    • 0027219533 scopus 로고
    • Terfenadine alters action potentials in isolated canine Purkinje fibers more than acrivastine. J
    • Lang DG, Wang CM, Wenger TL. Terfenadine alters action potentials in isolated canine Purkinje fibers more than acrivastine. J Cardiovasc Pharmacol. 1993;22:438-442.
    • (1993) Cardiovasc Pharmacol. , vol.22 , pp. 438-442
    • Lang, D.G.1    Wang, C.M.2    Wenger, T.L.3
  • 39
    • 0021971505 scopus 로고
    • Terfenadine: A review of its pharmaco-dynamic properties and therapeutic efficacy
    • Sorkin EM, Heel RC. Terfenadine: a review of its pharmaco-dynamic properties and therapeutic efficacy. Drugs. 1985;29:34-56.
    • (1985) Drugs. , vol.29 , pp. 34-56
    • Sorkin, E.M.1    Heel, R.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.