The neuroprotective effect of propofol against brain ischemia mediated by the glutamatergic signaling pathway in rats

Neurochemical Research

Volumn 36, Issue 10, 2011, Pages 1724-1731

  Cai, Jinsong ^a   Hu, Yuyan ^a   Li, Wenbin ^a,b   Li, L ^a   Li, Shuqin ^a   Zhang, Min ^a   Li, Qingjun ^a  

^a HEBEI MEDICAL UNIVERSITY   (China)

^b Aging and Cognition Neuroscience Laboratory of Hebei   (China)

Author keywords

Global brain ischemia; Glutamate uptake; Propofol; Radioligand binding assay; Rat

Indexed keywords

GLUTAMATE RECEPTOR; GLUTAMIC ACID; PROPOFOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; CONTROLLED STUDY; DISSOCIATION CONSTANT; DRUG EFFECT; HIPPOCAMPAL CA1 REGION; LIGAND BINDING; MALE; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT; RECEPTOR BINDING; SIGNAL TRANSDUCTION;

ANESTHETICS, INTRAVENOUS; ANIMALS; BRAIN ISCHEMIA; GLUTAMIC ACID; MALE; NEURONS; NEUROPROTECTIVE AGENTS; PROPOFOL; RANDOM ALLOCATION; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION;

RATTUS;

EID: 80555126829     PISSN: 03643190     EISSN: 15736903     Source Type: Journal    
DOI: 10.1007/s11064-011-0487-1     Document Type: Article

References (42)

1. Sitar SM, Hanifi Moghaddam P, Gelb A et al (1999) Propofol prevents peroxide-induced inhibition of glutamate transport in cultured astrocytes. Anesthesiology 90:1446-1453 (Pubitemid 29205650)
2. Peters CE, Korcok J, Gelb AW et al (2001) Anesthetic concentrations of propofol protect against oxidative stress in primary astrocyte cultures: Comparison with hypothermia. Anesthesiology 94:313-321 (Pubitemid 32125922)
3. Daskalopoulos R, Korcok J, Farhangkhgoee P et al (2001) Propofol protection of sodium-hydrogen exchange activity sustains glutamate uptake during oxidative stress. Anesth Analg 93:1199-1204 (Pubitemid 33021017)
4. Velly LJ, Guillet BA, Masmejean FM et al (2003) Neuroprotective effects of propofol in a model of ischemic cortical cell cultures: Role of glutamate and its transporters. Anesthesiology 99:368-375 (Pubitemid 36909562)
5. Wang J, Yang X, Camporesi CV et al (2002) Propofol reduces infarct size and striatal dopamine accumulation following transient middle cerebral artery occlusion: A microdialysis study. Eur J Pharmacol 452:303-308 (Pubitemid 35279433)
6. Bayona NA, Gelb AW, Jiang Z et al (2004) Propofol neuroprotection in cerebral ischemia and its effects on low-molecularweight antioxidants and skilled motor tasks. Anesthesiology 100:1151-1159 (Pubitemid 38541970)
7. Gelb AW, Bayona NA, Wilson JX et al (2002) Propofol anesthesia compared to awake reduces infarct size in rats. Anesthesiology 96:1183-1190 (Pubitemid 34462581)
8. Adembri C, Venturi L, Tani A et al (2006) Neuroprotective effects of propofol in models of cerebral ischemia: Inhibition of mitochondrial swelling as a possible mechanism. Anesthesiology 104:80-89
9. Ergün R, Akdemir G, Sen S et al (2002) Neuroprotective effects of propofol following global cerebral ischemia in rats. Neurosurg Rev 25:95-98 (Pubitemid 36055930)
10. Ito H, Watanabe Y, Isshiki A et al (1999) Neuroprotective properties of propofol and midazolam, but not pentobarbital, on neuronal damage induced by forebrain ischemia, based on the GABAA receptors. Acta Anaesthesiol Scand 43:153-162 (Pubitemid 29059308)
11. Yano T, Nakayama R, Ushijima K (2000) Intracerebroventricular propofol is neuroprotective against transient global ischemia in rats: Extracellular glutamate level is not a major determinant. Brain Res 883:69-76
12. Orser BA, Wang LY, Pennefather PS et al (1994) Propofol modulates activation and desensitization of GABAA receptors in cultured murine hippocampal neurons. J Neurosci 14:7747-7760
13. Lingamaneni R, Hemmings HC Jr (2003) Differential interaction of anaesthetics and antiepileptic drugs with neuronal Na ? channels, Ca2 ? channels, and GABA(A) receptors. Br J Anaesth 90:199-211 (Pubitemid 36181966)
14. Benveniste H, Jørgensen MB, Diemer NH et al (1988) Calcium accumulation by glutamate receptor activation is involved in hippocampal cell damage after ischemia. Acta Neurol Scand 78:529-536 (Pubitemid 19017793)
15. Shinohara Y, Yamamoto M, Haida M et al (1990) Effect of glutamate and its antagonist on shift of water from extra- to intracellular space after cerebral ischaemia. Acta Neurochir Suppl (Wien) 51:198-200
16. Szydlowska K, Tymianski M (2010) Calcium, ischemia and excitotoxicity. Cell Calcium 47:122-129
17. Zimmermann M (1983) Ethical guidelines for investigations of experimental pain in conscious animals. Pain 16:109-110 (Pubitemid 13058546)
18. Pulsinelli WA, Brierley JB (1979) A new model of bilateral hemispheric ischemia in the unanesthetized rat. Stroke 10:267-272 (Pubitemid 9141527)
19. Kitagawa K, Matsumoto M, Tagaya M et al (1990) 'Ischemic tolerance' phenomenon found in the brain. Brain Res 528:21-24 (Pubitemid 20292932)
20. Kato H, Liu Y, Araki T et al (1991) Temporal profile of the effects of pretreatment with brief cerebral ischemia on the neuronal damage following secondary ischemic insult in the gerbil: Cumulative damage and protective effects. Brain Res 553: 238-242
21. Meeker RB, Greenwood RS, Hayward JN (1994) Glutamate receptors in the rat hypothalamus and pituitary. Endocrinology 134:621-629 (Pubitemid 24057203)
22. Vesce S, Bezzi P, Rossi D et al (1997) HIV-1 gp120 glycoprotein astrocyte control of extracellular glutamate by both inhibiting the uptake and stimulating the release of the amino acid. FEBS lett 411:107-109 (Pubitemid 27298381)
23. Tasca CI, Santos TG, Tavares RG et al (2004) Guanine derivatives modulate 1- glutamate uptake into rat brain synaptic vesicles. Neurochem Int 44:423-431 (Pubitemid 37548407)
24. dos Santos AQ, Nardin P, Funchal C et al (2006) Resveratrol increases glutamate uptake and glutamine synthetase activity in C6 glioma cells. Arch Biochem Biophys 453:161-167 (Pubitemid 44344218)
25. Sakai T, Yoshitoshi T, Nagai Y et al (2006) Increased glutamate uptake and GLAST expression by cyclic AMP in retinal glial cells. Graefes Arch Clin Exp Ophthalmol 244:359-363
26. Moretto MB, Thomazi AP, Godinho G et al (2007) Ebselen and dilrg- anyl chalcogenides decrease in vitro glutamate uptake by rat brain slices: Prevention by DTT and GSH. Toxicol In Vitro 21:639-645 (Pubitemid 46550749)
27. Fernández-Tomé P, Brera B, Arévalo MA et al (2004) b-Amyloid25- 35 inhibits glutamate uptake in cultured neurons and astrocytes: Modulation of uptake as a survival mechanism. Neurobiol Dis 15:580-589
28. Oshima T, Karasawa F, Satoh T (2002) Effects of propofol on cerebral blood flow and the metabolic rate of oxygen in humans. Acta Anaesthesiol Scand 46:831-835 (Pubitemid 34800076)
29. Newman MF, Murkin JM, Roach G et al (1995) Cerebral physiologic effects of burst suppression doses of propofol during nonpulsatile cardiopulmonary bypass. Anesth Analg 81:452-457
30. De La Cruz JP, Sedeño G, Carmona JA et al (1998) The in vitro effects of propofol on tissular oxidative stress in the rat. Anesth Analg 87:1141-1146 (Pubitemid 28501175)
31. Grasshoff C, Gillessen T (2002) The effect of propofol on increased superoxide concentration in cultured rat cerebrocortical neurons after stimulation of N-methyl-D-aspartate receptors. Anesth Analg 95:920-922
32. Lingamaneni R, Birch ML, Hemmings HC Jr (2001) Widespread inhibition of sodium channel-dependent glutamate release from isolated nerve terminals by isoflurane and propofol. Anesthesiology 95:1460-1466 (Pubitemid 33126759)
33. Ratnakumari L, Hemmings HC Jr (1997) Effects of propofol on sodium channel-dependent sodium influx and glutamate release in rat cerebrocortical synaptosomes. Anesthesiology 86:428-439 (Pubitemid 27093387)
34. Benveniste H, Drejer J, Schousboe A et al (1984) Elevation of the extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis. J Neurochem 43:1369-1374 (Pubitemid 15205893)
35. Shimada N, Graf R, Rosner G et al (1993) Ischemia-induced accumulation of extracellular amino acids in cerebral cortex, white matter, and cerebrospinal fluid. J Neurochem 60:66-71 (Pubitemid 23006703)
36. Uchiyama-Tsuyuki Y, Araki H, Yae T et al (1994) Changes in the extracellular concentrations of amino acids in the rat striatum during transient focal cerebral ischemia. J Neurochem 62:1074-1078 (Pubitemid 24064521)
37. Vernier P, Cardinaud B, Valdenaire O et al (1995) An evolutionary view of drug-receptor interaction: The bioamine receptor family. Trends Pharmacol Sci 16:375-381
38. Lee FJ, Wang YT, Liu F (2005) Direct receptor cross-talk can mediate the modulation of excitatory and inhibitory neurotransmission by dopamine. J Mol Neurosci 26:245-252
39. Danbolt NC (1994) The high affinity uptake system for excitatory amino acids in the brain. Prog Neurobiol 44:377-396 (Pubitemid 24337092)
40. Schousboe A (1981) Transport and metabolism of glutamate and GABA in neurons are glial cells. Int Rev Neurobiol 22:1-45
41. Fraser DD, Duffy S, Angelides KJ et al (1995) GABAA/benzodiazepine receptors in acutely isolated hippocampal astrocytes. J Neurosci 15:2720-2732
42. Bovolin P, Santi MR, Puia G et al (1992) Expression patterns of gamma- aminobutyric acid type A receptor subunit mRNAs in primary cultures of granule neurons and astrocytes from neonatal rat cerebella. Proc Natl Acad Sci USA 89:9344-9348