Neuroprotective effects of propofol following global cerebral ischemia in rats

Neurosurgical Review

Volumn 25, Issue 1-2, 2002, Pages 95-98

  Ergün, Rüçhan ^a,b   Akdemir, Gökhan ^b   Şen, Sibel ^b   Taşçi, Alptekin ^b   Ergüngör, Fikret ^b  

^a Ankara Numune Hospital ^*  (Turkey)

^b ANKARA NUMUNE HOSPITAL   (Turkey)

Author keywords

Cerebral ischemia; Neuroprotection; Propofol; Rat

Indexed keywords

BARBITURIC ACID DERIVATIVE; MALONALDEHYDE; PROPOFOL;

ANESTHESIA INDUCTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL OCCLUSION; BRAIN BLOOD FLOW; BRAIN ISCHEMIA; CELL DEATH; CEREBROVASCULAR DISEASE; CONTROLLED STUDY; INTRACRANIAL PRESSURE; LIPID PEROXIDATION; MALE; METABOLIC RATE; METABOLISM; NERVE CELL; NEUROPROTECTION; NEUROSURGERY; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION;

ANESTHETICS, INTRAVENOUS; ANIMALS; BRAIN ISCHEMIA; LIPID PEROXIDES; MALE; MALONDIALDEHYDE; NEUROPROTECTIVE AGENTS; PROPOFOL; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY;

EID: 0036936431     PISSN: 03445607     EISSN: None     Source Type: Journal    
DOI: 10.1007/s101430100171     Document Type: Article

References (35)

1. Arcadi F, Rapisarda A, De Luca R, Trimarchi G, Costa G (1996) Effect of 2,6-diisopropylphenol on the delayed hippocampal cell loss following transient forebrain ischemia in the gerbil. Life Sci 12:961-970
2. Batjer HH, Frankfurt AI, Purdy PD (1988) Use of etomidate, temporary arterial occlusion, and intraoperative angiography in surgical treatment of large and giant cerebral aneurysms. J Neurosurg 68:234-240
3. Bird RP, Draper HH (1984) Comparative studies of different methods of malondialdehyde determination. Methods Enzymol 105:299-305
4. Cervantes M, Ruelas R, Chavez-Carrillo I, Contreras-Gomez A, Antonio-Ocampo A (1995) Effects of propofol on alterations of multineuronal activity of limbic and mesencephalic structures and neurologic deficit eliminated by acute global cerebral ischemia. Arch Med Res 4:385-395
5. Dam M, Ori C, Pizzolato G (1990) The effects of propofol anesthesia on local cerebral glucose utilization in the rat. Anesthesiology 73:499-505
6. A receptor subunit. Nature 385:820-823
7. Goldman MS, Anderson RE, Meyer FB (1992) Effects of intermittent reperfusion during temporal focal ischemia. J Neurosurg 77:911-916
8. Ito H, Watanabe Y, Isshiki A, Uchino H (1999) Neuroprotective properties of propofol and midazolam, but not pentobarbital, on neuronal damage induced by forebrain ischemia, based on the GABAA receptors. Acta Anaesthesiol Scand 43:153-162
9. Iuliano BA, Anderson RE, Meyer FB (1995) Effects of intermittent reperfusion and nitric oxide synthase inhibition on infarct volume during reversible focal cerebral ischemia. J Neurosurg 83:491-495
10. Jensen U, Becker H (1993) Preservation of cerebral ischemia under general anesthesia. Eur J Vasc Endovasc Surg 7 [Suppl A]:8-12
11. Kahn R, Panah M, Kiffel S, Weinberger J (1997) Modulation of ischemic excitatory neurotransmitter and γ-aminobutyric acid release during global temporary cerebral ischemia by local nitric oxide synthase inhibition. Anesth Analg 84:1004-1010
12. Kahraman S, Demiryürek AT (1997) Propofol is a peroxynitrite scavenger. Anesth Analg 84:1127-1129
13. Kochs E, Hoffman WE, Wemer C, Thomas C, Albrecht RF, Esch JS (1992) The effects of propofol on brain electrical activity, neurologic outcome, and neuronal damage following incomplete ischemia in rats. Anesthesiology 76:245-252
14. Lavine SD, Masri LS, Levy ML, Giannotta SL (1997) Temporary occlusion of the middle cerebral artery in intracranial aneurysm surgery: time limitation and advantage of brain protection. J Neurosurg 87:817-824
15. McDermott MW, Durity FA, Borozny M (1989) Temporary vessel occlusion and barbiturate protection in cerebral aneurysm surgery. Neurosurgery 25:54-62
16. Muizelaar JP (1989) The use of electroencephalography and brain protection during operation for basilar aneurysms. Neurosurgery 25:899-903
17. Murphy PG, Davies MJ, Columb MO, Stratford N (1996) Effect of propofol and thiopentone on free radical mediated oxidative stress of the erythrocyte. Br J Anaesth 76:536-543
18. Nakashima K, Todd M (1996) Effects of hypothermia, pentobarbital, and isoflurane on postdepolarization amino acid release during complete global cerebral ischemia. Anesthesiology 85:161-168
19. Ohnishi M, Watanabe Y, Shibuya T (1995) Potentiation of excitotoxicity by glutamate uptake rather than glutamine synthetase inhibitor. Jpn J Pharmacol 68:315-321
20. Ooboshi H, Sasashima S, Yao H, Nakahara T, Uchimura H, Fujishima M (1992) Inhibition of ischemia-induced dopamine release by w-conotoxin, a calcium channel blocker, in the striatum of spontaneously hypertensive rats: an in vivo brain dialysis study. J Neurochem 58:298-303
21. O'Regan M, Smith-Barbour M, Perkins L, Phillis J (1995) A possible role for phospholipases in the release of neurotransmitter amino acids from ischemic rat cerebral cortex. Neurosci Lett 3:191-194
22. Orser BA, Bertilik M, Want LY, MacDonald JF (1995) Inhibition by propofol (2,6 diisopropylphenol) of the N-methyl-D-aspartate subtype of glutamate receptor in cultured hippocampal neurones. Br J Pharmacol 116:1761-1768
23. Peduto VA, Concas A, Santoro G, Biggio G, Gessa GL (1991) Biochemical and electrophysiologic evidence that propofol enhances GABAergic transmission in the rat brain. Anesthesiology 75:1000-1009
24. Pinaud M, Lelausque JN, Chetanneau A, Fauchoux N, Ménégalli D, Sauron R (1990) Effects of propofol on cerebral hemodynamics and metabolism in patients with brain trauma. Anesthesiology 73:404-409
25. Pulsinelli WA, Brierley JB (1979) A new model of bilateral hemispheric ischemia in the unanesthetized rat. Stroke 10:267-271
26. Ravussin P, Guinard JP, Ralley F, Thorin D (1988) Effect of propofol on cerebrospinal fluid pressure and cerebral perfusion pressure in patients undergoing craniotomy. Anesthesia 43:37-41
27. Roserwasser RH, Jimenez F, Wending WW (1991) Routine use of etomidate and temporary vessel occlusion during aneurysm surgery. Neurol Res 13:224-228
28. Sano T, Patel PM, Drummond JC, Cole DJ (1993) A comparison of the cerebral protective effects of etominate, thiopental, and isoflurane in a model of forebrain ischemia in the rat. Anesth Analg 76:990-997
29. Schwartz RD, Yu X, Wagner J, Ehrmann M, Mileson BE (1992) Cellular regulation of the benzodiazepine/GABA receptor; arachidonic acid, calcium, and cerebral ischemia. Neuropsychopharmacology 6:119-125
30. Selman WR, Bhatti SU, Rosenstein CC (1994) Temporary vessel occlusion in spontaneously hypertensive and normotensive rats. Effect of single and multiple episodes on tissue metabolism and volume infarction. J Neurosurg 80:1085-1090
31. Steinberg GK, Panahian N, Sun GH (1994) Cerebral damage caused by interrupted, repeated arterial occlusion versus uninterrupted occlusion in a focal ischemic model. J Neurosurg 81:554-559
32. Van Hemelrijck J, Fitch W, Mattheussen M, Van Aken H, Plets C, Lauwers T (1990) Effects of propofol on cerebral circulation and autoregulation in the baboon. Anesth Analg 71:49-54
33. Watts ADJ, Eliasziw M, Gelb AW (1998) Propofol and hyperventilation for the treatment of increased intracranial pressure in rabbits. Anesth Analg 87:564-568
34. Yamaguchi S, Midorikawa Y, Okuda Y, Kitajima T (1999) Propofol prevents delayed neuronal death following transient forebrain ischemia in gerbils. Can J Anaesth 46:593-598
35. Young Y, Menon D, Matta B, Jones J (1997) Propofol neuroprotection in a rat model of ischemia reperfusion injury. Eur J Anaesthesiol 3:320-326