Histone deacetylase inhibitor trichostatin A enhances myogenesis by coordinating muscle regulatory factors and myogenic repressors

Biochemical and Biophysical Research Communications

Volumn 414, Issue 4, 2011, Pages 826-831

  Hagiwara, Hiroki ^a,b   Saito, Fumiaki ^a   Masaki, Toshihiro ^a,b   Ikeda, Miki ^a   Nakamura Ohkuma, Ayami ^a   Shimizu, Teruo ^a   Matsumura, Kiichiro ^a  

^a TEIKYO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b TEIKYO UNIVERSITY OF SCIENCE   (Japan)

Author keywords

Dystrophin associated proteins complex; Histone deacetylase inhibitors; Muscular dystrophy; Myogenic regulatory factors; Myogenic repressors

Indexed keywords

BONE MORPHOGENETIC PROTEIN 4; CAVEOLIN 3; CREATINE KINASE MM; DESMIN; DYSTROGLYCAN; DYSTROPHIN; DYSTROPHIN ASSOCIATED PROTEIN COMPLEX; FOLLISTATIN; INHIBITOR OF DIFFERENTIATION 1; INHIBITOR OF DIFFERENTIATION 2; INHIBITOR OF DIFFERENTIATION 3; LAMININ ALPHA2; MYOCYTE ENHANCER FACTOR 2; MYOD1 PROTEIN; MYOGENIC FACTOR; MYOGENIC FACTOR 5; MYOGENIC FACTOR 6; MYOGENIN; MYOSIN HEAVY CHAIN; MYOSTATIN; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD4 PROTEIN; SMAD7 PROTEIN; TRANSCRIPTION FACTOR PAX3; TRANSCRIPTION FACTOR PAX7; TRICHOSTATIN A; TROPONIN C; TROPONIN I; TROPONIN T; UNCLASSIFIED DRUG;

ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; DRUG EFFECT; GENE EXPRESSION; MUSCLE DEVELOPMENT; MYOBLAST; MYOTUBE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SKELETAL MUSCLE;

ANIMALS; CELL LINE; DYSTROPHIN-ASSOCIATED PROTEIN COMPLEX; GENE EXPRESSION; HISTONE DEACETYLASE INHIBITORS; HYDROXAMIC ACIDS; INHIBITOR OF DIFFERENTIATION PROTEIN 1; INHIBITOR OF DIFFERENTIATION PROTEIN 2; INHIBITOR OF DIFFERENTIATION PROTEINS; MICE; MUSCLE DEVELOPMENT; MUSCLE, SKELETAL; MYOGENIC REGULATORY FACTOR 5; MYOGENIC REGULATORY FACTORS; MYOSIN HEAVY CHAINS;

EID: 80555122762     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.10.036     Document Type: Article

References (24)

1. Feinberg A.P. Epigenetics at the epicenter of modern medicine. Jama 2008, 299:1345-1350.
2. Peterson C.L. HDAC's at work: everyone doing their part. Molecular Cell 2002, 9:921-922.
3. Kuo M.H., Allis C.D. Roles of histone acetyltransferases and deacetylases in gene regulation. BioEssays 1998, 20:615-626.
4. Riester D., Hildmann C., Schwienhorst A. Histone deacetylase inhibitors - turning epigenic mechanisms of gene regulation into tools of therapeutic intervention in malignant and other diseases. Applied Microbiology and Biotechnology 2007, 75:499-514.
5. Santini V., Gozzini A., Ferrari G. Histone deacetylase inhibitors: molecular and biological activity as a premise to clinical application. Current Drug Metabolism 2007, 8:383-393.
6. Emery A.E. The muscular dystrophies. Lancet 2002, 359:687-695.
7. Perry R.L., Rudnick M.A. Molecular mechanisms regulating myogenic determination and differentiation. Frontiers in Biosciences 2000, 5:D750-D767.
8. Iezzi S., Cossu G., Nervi C., Sartorelli V., Puri P.L. Stage-specific modulation of skeletal myogenesis by inhibitors of nuclear deacetylases. Proceedings of the National Academy of Sciences of the United States of America 2002, 99:7757-7762.
9. Iezzi S., Di Padova M., Serra C., Caretti G., Simone C., Maklan E., Minetti G., Zhao P., Hoffman E.P., Puri P.L., Sartorelli V. Deacetylase inhibitors increase muscle cell size by promoting myoblast recruitment and fusion through induction of follistatin. Developmental Cell 2004, 6:673-684.
10. Minetti G.C., Colussi C., Adami R., Serra C., Mozzetta C., Parente V., Fortuni S., Straino S., Sampaolesi M., Di Padova M., Illi B., Gallinari P., Steinkuhler C., Capogrossi M.C., Sartorelli V., Bottinelli R., Gaetano C., Puri P.L. Functional and morphological recovery of dystrophic muscles in mice treated with deacetylase inhibitors. Nature Medicine 2006, 12:1147-1150.
11. Colussi C., Mozzetta C., Gurtner A., Illi B., Rosati J., Straino S., Ragone G., Pescatori M., Zaccagnini G., Antonini A., Minetti G., Martelli F., Piaggio G., Gallinari P., Steinkuhler C., Clementi E., Dell'Aversana C., Altucci L., Mai A., Capogrossi M.C., Puri P.L., Gaetano C. HDAC2 blockade by nitric oxide and histone deacetylase inhibitors reveals a common target in Duchenne muscular dystrophy treatment. Proceedings of the National Academy of Sciences of the United States of America 2008, 105:19183-19187.
12. Yoshida M., Horinouchi S., Beppu T. Trichostatin A and trapoxin: novel chemical probes for the role of histone acetylation in chromatin structure and function. BioEssays 1995, 17:423-430.
13. Benezra R., Davis R.L., Lassar A., Tapscott S., Thayer M., Lockshon D., Weintraub H. Id: a negative regulator of helix-loop-helix DNA binding proteins. Control of terminal myogenic differentiation. Annals of the New York Academy of Sciences 1990, 599:1-11.
14. Saito F., Saito-Arai Y., Nakamura A., Shimizu T., Matsumura K. Processing and secretion of the N-terminal domain of alpha-dystroglycan in cell culture media. FEBS Letters 2008, 582:439-444.
15. Saito F., Masaki T., Saito Y., Nakamura A., Takeda S., Shimizu T., Toda T., Matsumura K. Defective peripheral nerve myelination and neuromuscular junction formation in fukutin-deficient chimeric mice. Journal of Neurochemistry 2007, 101:1712-1722.
16. Matsumura K., Zhong D., Saito F., Arai K., Adachi K., Kawai H., Higuchi I., Nishino I., Shimizu T. Proteolysis of beta-dystroglycan in muscular diseases. Neuromuscular Disorders 2005, 15:336-341.
17. Zhong D., Saito F., Saito Y., Nakamura A., Shimizu T., Matsumura K. Characterization of the protease activity that cleaves the extracellular domain of beta-dystroglycan. Biochemical and Biophysical Research Communications 2006, 345:867-871.
18. Buckingham M. Skeletal muscle formation in vertebrates. Current Opinion in Genetics and Development 2001, 11:440-448.
19. Lu J., McKinsey T.A., Nicol R.L., Olson E.N. Signal-dependent activation of the MEF2 transcription factor by dissociation from histone deacetylases. Proceedings of the National Academy of Sciences of the United States of America 2000, 97:4070-4075.
20. McKinsey T.A., Zhang C.L., Lu J., Olson E.N. Signal-dependent nuclear export of a histone deacetylase regulates muscle differentiation. Nature 2000, 408:106-111.
21. McKinsey T.A., Zhang C.L., Olson E.N. Signaling chromatin to make muscle. Current Opinion in Cell Biology 2002, 14:763-772.
22. Palacios D., Puri P.L. The epigenetic network regulating muscle development and regeneration. Journal of Cellular Physiology 2006, 207:1-11.
23. Hosseinkhani M., Hasegawa K., Ono K., Kawamura T., Takaya T., Morimoto T., Wada H., Shimatsu A., Prat S.G., Suemori H., Nakatsuji N., Kita T. Trichostatin A induces myocardial differentiation of monkey ES cells. Biochemical and Biophysical Research Communications 2007, 356:386-391.
24. Kaichi S., Hasegawa K., Takaya T., Yokoo N., Mima T., Kawamura T., Morimoto T., Ono K., Baba S., Doi H., Yamanaka S., Nakahata T., Heike T. Cell line-dependent differentiation of induced pluripotent stem cells into cardiomyocytes in mice. Cardiovascular Research 2010, 88:314-323.