Effect of oophorectomy and estrogen administration on diabetic pathogenesis in female spontaneously diabetic Torii rats

Open Diabetes Journal

Volumn 4, Issue SPEC. ISSUE 1, 2011, Pages 96-100

  Shinohara, Masami ^a   Oikawa, Toshihiro ^b   Sato, Kahei ^c   Kanazawa, Yasunori ^d  

^a CLEA Japan Inc   (Japan)

^b Torii Nihonbashi Building   (Japan)

^c NIHON UNIVERSITY   (Japan)

^d JICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

Body weight; Estrogen; Female SDT rats; Oophorectomy; Pancreatic histopathology; Plasma glucose

Indexed keywords

ESTRADIOL BENZOATE; GLUCOSE; INSULIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DIABETES MELLITUS; DIABETOGENESIS; DOWN REGULATION; DRUG ACTIVITY; DRUG EFFECT; DRUG MECHANISM; ESTROGEN ACTIVITY; FEMALE; GLUCOSE BLOOD LEVEL; HISTOPATHOLOGY; INFLAMMATORY INFILTRATE; NONHUMAN; OUTCOME ASSESSMENT; OVARIECTOMY; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; RAT; RAT STRAIN; SPONTANEOUSLY DIABETIC TORII RAT; WEIGHT CHANGE; WEIGHT GAIN;

EID: 80455174149     PISSN: None     EISSN: 18765246     Source Type: Journal    
DOI: 10.2174/1876524601104010096     Document Type: Article

References (30)

1. Shinohara M, Masuyama T, Shoda T, et al. A new spontaneously diabetic non-obese Torii rat strain with severe ocular complications. Int J Exp Diabetes Res 2000; 1: 89-100.
2. Shinohara M, Masuyama T, Kakehashi A. The Spontaneously Diabetic Torii (SDT) rat with retinopathy lesions resembling those of humans. In Shafrir E, Ed. Animal models of diabetes: frontiers in research. 2nd ed. CRC Press, Boca Raton, FL, USA 2007; pp. 311-21.
3. Yamada H, Yamada E, Higuchi A, Matsumura M. Retinal neovascularisation without ischaemia in the spontaneously Diabetic Torii rat. Diabetologia 2005; 48: 1663-8.
4. Kakehashi A, Saito Y, Mori K, et al. Characteristics of diabetic retinopathy in SDT rats. Diabetes Metab Res Rev 2006; 22: 455-61.
5. Sasase T, Ohta T, Ogawa N, et al. Preventive effects of glycaemic control on ocular complications of the Spontaneously Diabetic Torii rat. Diabetes Obes Metab 2006; 8: 501-7.
6. Shoda T, Shinohara M, Takahashi T, Miyajima K, Kakehashi A, Miyakawa Y. Histopathological features of diabetic ocular complications in the spontaneously Diabetic Torii (SDT) rat. J Toxicol Pathol 2007; 20: 179-83.
7. Okuno T, Oku H, Sugiyama T, Ikeda T. Electroretinographic study of spontaneously Diabetic Torii rats. Doc Ophthalmol 2008; 117: 191-6.
8. Sasase T, Ohta T, Ogawa N, et al. Diabetic complications of the Spontaneously Diabetic Torii rat. Diabetes 2005; 54: Suppl 1: A221.
9. Sasase T, Morinaga H, Abe T, et al. Protein kinase C beta inhibitor prevents diabetic peripheral neuropathy, but not histopathological abnormalities of retina in the Spontaneously Diabetic Torii rat. Diabetes Obes Metab 2009; 11: 1084-87.
10. Fukuda M, Nakanishi Y, Fuse M, et al. Altered expression of aquaporins 1 and 4 coincides with neurodegenerative events in retinas of spontaneously diabetic Torii rats. Exp Eye Res 2010; 90: 17-25.
11. Ohta T, Matsui K, Miyajima K, et al. Effect of insulin therapy on renal changes in spontaneously diabetic Torii rats. Exp Anim 2007; 56: 355-62.
12. Fujii H, Kono K, Nakai K, et al. Oxidative and nitrosative stress and progression of diabetic nephropathy in type 2 diabetes. Am J Nephrol 2010; 31: 342-52.
13. Masuyama T, Komeda K, Hara A, et al. Chronological characterization of diabetes development in male spontaneously Diabetic Torii rats. Biochem Biophys Res Commun 2004; 314: 870-7.
14. Sasase T, Morinaga H, Yamamoto H, et al. Increased fat absorption and impaired fat clearance cause postprandial hypertriglyceridemia in spontaneously Diabetic Torii rats. Diabetes Res Clin Pract 2007; 78: 8-15.
15. Masuyama T, Fuse M, Yokoi N, et al. Genetic analysis for diabetes in a new rat model of nonobese type 2 diabetes, the spontaneously Diabetic Torii rat. Biochem Biophys Res Commun 2003; 304: 196-206.
16. Fuse M, Yokoi N, Shinohara M, et al. Identification of a major locus for islet inflammation and fibrosis in the spontaneously Diabetic Torii rat. Physiol Genom 2008; 35: 96-105.
17. Shinohara M, Oikawa T, Sato K, Kanazawa Y. Glucose intolerance and hyperlipidemia prior to diabetes onset in female spontaneously Diabetic Torii (SDT) rats. Exp Diabesity Res 2004; 5: 253-56.
18. Rossini AA, Williams RM, Appel MC, Like AA. Sex differences in the multiple-dose streptozotocin model of diabetes. Endocrinology 1978; 103: 1518-20.
19. Shi K, Mizuno A, Sato T, Ishida K, Shima K. Sexual difference in the incidence of diabetes mellitus in Otsuka-Long-Evans-Tokushima-Fatty rats: effects of castration and sex hormone replacement on its incidence. Metabolism 1994; 43: 1214-20.
20. Kava RA, West DB, and Lukasik VA, et al. The effects of gonadectomy on glucose tolerance of genetically obese (fa/fa) rats: influence of sex and genetic background. Int J Obes (Lond) 1992; 16: 103-11.
21. Tarres MC, Martinez SM, Montenegro SM, Figueroa NS, D'Ottavio AE, Picena JC. Influence of gonadectomy in eSS diabetic rats. J Physiol Biochem 1997; 53: 211-16.
22. Rushakoff RJ, Kalkhoff RK. Effects of pregnancy and sex steroid administration on skeletal muscle metabolism in the rat. Diabetes 1981; 30: 545-50.
23. Mandour T, Kissebah AH, Wynn V. Mechanism of oestrogen and progesterone effects on lipid and carbohydrate metabolism: alteration in the insulin:glucagon molar ratio and hepatic enzyme activity. Eur J Clin Invest 1977; 7: 181-87.
24. Prochazka M, Premdas FH, Leiter EH, Lipson LG. Estrone treatment dissociates primary versus secondary consequences of "Diabetes" (db) gene expression in mice. Diabetes 1986; 35: 725-28.
25. Le May C, Chu K, Hu M, et al. Estrogens protect pancreatic beta-cells from apoptosis and prevent insulin-deficient diabetes mellitus in mice. Proc Natl Acad Sci USA 2006; 103: 9232-37.
26. Paik SG, M. Michelis MA, Y, Kim YT, Shin M. Induction of insulin-dependent diabetes by streptozotocin. Inhibition by estrogens and potentiation by androgens. Diabetes 1982; 31: 724-729.
27. Kahn SE, Andrikopoulos S, Verchere CB, Wang F, Hull RL, Vidal J. Oophorectomy promotes islet amyloid formation in a transgenic mouse model of type II diabetes. Diabetologia 2000; 43: 1309-12.
28. Tiano JP, Le May C, Hu M, Mauvais-Jarvis F. Estrogens improve genetic leptin resistance and prevent p-cell lipotoxicity. Program of the 90th Annual Meeting of the Endocrine Society, San Francisco, CA, 2008, pp141 (Abstract OR 37-5).
29. Zhu M, Mizuno A, Kuwajima M, et al. Ovarian hormone-induced p-cell hypertrophy contributes to the homeostatic control of p-cell mass in the OLETF female rat, a model of type II diabetes. Diabetologia 1998; 41: 799-805.
30. Liu S, Mauvais-Jarvis F. Minireview: estrogenic protection of beta-cell failure in metabolic diseases. Endocrinology 2010; 151: 859-64.