Neutralization of chemokine CXCL14 (BRAK) expression reduces CCl 4 induced liver injury and steatosis in mice

European Journal of Pharmacology

Volumn 671, Issue 1-3, 2011, Pages 120-127

  Li, Jingjing ^a   Gao, Jin ^b   Yan, Dejun ^a   Yuan, Yunsheng ^a   Sah, Sunita ^b   Satyal, Uttam ^b   Liu, Man ^a   Han, Wei ^b   Yu, Yan ^a  

^a SJTU Cornell Institute of Sustainable Agriculture and Biotechnology   (China)

^b SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

CCl4; CXCL14; CXCL14 antibody; Lipid peroxidation; Liver failure; Steatosis

Indexed keywords

CARBON TETRACHLORIDE; CXCL14 CHEMOKINE; PLASMID DNA; RECOMBINANT CXCL14 CHEMOKINE; UNCLASSIFIED DRUG;

ACUTE LIVER FAILURE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL CYCLE ARREST; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISEASE SEVERITY; FATTY LIVER; LIPID PEROXIDATION; LIVER INJURY; LIVER NECROSIS; MALE; MORTALITY; MOUSE; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROTEIN EXPRESSION; RABBIT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STEATOSIS; UPREGULATION;

ANIMALS; ANTIBODIES, NEUTRALIZING; CARBON TETRACHLORIDE; CELL PROLIFERATION; CHEMOKINES, CXC; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; DRUG-INDUCED LIVER INJURY; FATTY ACIDS; FATTY LIVER; FEMALE; GENE EXPRESSION REGULATION; HEPATOCYTES; IMMUNE SERA; LIPID PEROXIDATION; LIVER FAILURE; LIVER REGENERATION; MALE; MICE; NECROSIS; PLASMIDS; TRANSCRIPTION, GENETIC; TRANSFECTION; UP-REGULATION;

EID: 80455160160     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2011.09.174     Document Type: Article

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