Manipulating the fragile X mental retardation proteins in the frog

Results and Problems in Cell Differentiation

Volumn 54, Issue , 2012, Pages 165-179

  Huot, Marc Etienne ^a   Bisson, Nicolas ^b   Moss, Thomas ^a   Khandjian, Edouard W ^c  

^a LAVAL UNIVERSITY   (Canada)

^b MOUNT SINAI HOSPITAL   (Canada)

^c CENTRE DE RECHERCHE DE L INSTITUT UNIVERSITAIRE EN SANTÉ MENTALE DE QUÉBEC   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

FRAGILE X MENTAL RETARDATION PROTEIN; MESSENGER RNA; MORPHOLINO OLIGONUCLEOTIDE; XENOPUS PROTEIN;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; CLASSIFICATION; GENE EXPRESSION REGULATION; GENE SILENCING; GENETICS; METABOLISM; MOLECULAR GENETICS; MOUSE; PHYLOGENY; PHYSIOLOGY; PRENATAL DEVELOPMENT; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY; TISSUE DISTRIBUTION; XENOPUS;

AMINO ACID SEQUENCE; ANIMALS; FRAGILE X MENTAL RETARDATION PROTEIN; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE KNOCKDOWN TECHNIQUES; MICE; MOLECULAR SEQUENCE DATA; MORPHOLINOS; PHYLOGENY; RNA, MESSENGER; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; TISSUE DISTRIBUTION; XENOPUS; XENOPUS PROTEINS;

EID: 80455131062     PISSN: 00801844     EISSN: 18610412     Source Type: Book Series    
DOI: 10.1007/978-3-642-21649-7_9     Document Type: Article

References (47)

1. Antar LN, Afroz R, Dictenberg JB, Carroll RC, Bassell GJ (2004) Metabotropic glutamate receptor activation regulates fragile x mental retardation protein and FMR1 mRNA localization differentially in dendrites and at synapses. J Neurosci 24:2648-2655
2. Bakker CE, Verheij C, Willemsen R, Van der Helm R, Oerlemans F, Vermey M, Bygrave A, Hoogeveen AT, Oostra BA (1994) Fmr1 knockout mice: a model to study fragile X mental retardation. Cell 78:23-33
3. Bakker CE, de Diego OY, Bontekoe C, Raghoe P, Luteijn T, Hoogeveen AT, Oostra BA, Willemsen R (2000) Immunocytochemical and biochemical characterization of FMRP, FXR1P, and FXR2P in the mouse. Exp Cell Res 258:162-170
4. Bardoni B, Davidovic L, Bensaid M, Khandjian EW (2006) The fragile X syndrome: exploring its molecular basis and seeking a treatment. Expert Rev Mol Med 8:1-16
5. Bechara E, Davidovic L, Melko M, Bensaid M, Tremblay S, Grosgeorge J, Khandjian EW, Lalli E, Bardoni B (2007) Fragile X related protein 1 isoforms differentially modulate the affinity of fragile X mental retardation protein for G-quartet RNA structure. Nucleic Acids Res 35:299-306
6. Bill BR, Petzold AM, Clark KJ, Schimmenti LA, Ekker SC (2009) A primer for morpholino use in zebrafish. Zebrafish 6:69-77
7. Blonden L, van't Padje S, Severijnen LA, Destree O, Oostra BA, Willemsen R (2005) Two members of the Fxr gene family, Fmr1 and Fxr1, are differentially expressed in Xenopus tropicalis. Int J Dev Biol 49:437-441
8. Bontekoe CJ, McIlwain KL, Nieuwenhuizen IM, Yuva-Paylor LA, Nellis A, Willemsen R, Fang Z, Kirkpatrick L, Bakker CE, McAninch R et al (2002) Knockout mouse model for Fxr2: a model for mental retardation. Hum Mol Genet 11:487-498
9. Coffee RL Jr, Tessier CR, Woodruff EA 3rd, Broadie K (2010) Fragile X mental retardation protein has a unique, evolutionarily conserved neuronal function not shared with FXR1P or FXR2P. Dis Model Mech 3:471-485
10. Cripe L, Morris E, Fulton AB (1993) Vimentin mRNA location changes during muscle development. Proc Natl Acad Sci USA 90:2724-2728
11. Cunningham CL, Martinez Cerdeno V, Navarro E, Prakash A, Angelastro JM, Willemsen R, Hagerman PJ, Pessah IN, Berman RF, Noctor SC (2011) Premutation CGG-repeat expansion of the Fmr1 gene impairs mouse neocortical development. Hum Mol Genet 20:64-79
12. Darnell JC, Jensen KB, Jin P, Brown V,Warren ST, Darnell RB (2001) Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function. Cell 107:489-499
13. Darnell JC, Fraser CE, Mostovetsky O, Darnell RB (2009) Discrimination of common and unique RNA-binding activities among Fragile X mental retardation protein paralogs. Hum Mol Genet 18:3164-3177
14. Davidovic L, Tremblay S, De Koninck P, Khandjian EW (2005) Fragile X mental retardation protein: to be or not to be a translational repressor. In: Sung Y-J, Denman RB (eds) The molecular basis of fragile X syndrome. Research Signpost, Trivandrum, pp 129-143
15. De Diego OY, Severijnen LA, van Cappellen G, Schrier M, Oostra B, Willemsen R (2002) Transport of fragile X mental retardation protein via granules in neurites of PC12 cells. Mol Cell Biol 22:8332-8341
16. Dobkin C, Rabe A, Dumas R, El Idrissi A, Haubenstock H, Brown WT (2000) Fmr1 knockout ouse has a distinctive strain-specific learning impairment. Neuroscience 100:423-429
17. Dube M, Huot ME, Khandjian EW (2000) Muscle specific fragile X related protein 1 isoforms are sequestered in the nucleus of undifferentiated myoblast. BMC Genet 1:4
18. Eisen JS, Smith JC (2008) Controlling morpholino experiments: don't stop making antisense. Development 135:1735-1743
19. Engels B, van't Padje S, Blonden L, Severijnen LA, Oostra BA, Willemsen R (2004) Characterization of Fxr1 in Danio rerio: a simple vertebrate model to study costamere development. J Exp Biol 207:3329-3338
20. Fulton AB, Alftine C (1997) Organization of protein and mRNA for titin and other myofibril components during myofibrillogenesis in cultured chicken skeletal muscle. Cell Struct Funct 22:51-58
21. Gessert S, Bugner V, Tecza A, Pinker M, Kuhl M (2010) FMR1/FXR1 and the miRNA pathway are required for eye and neural crest development. Dev Biol 341:222-235
22. Greenspan RJ (2007) An introduction to nervous systems. Cold Spring Harbor Laboratory Press, New York
23. Guduric-Fuchs J, Mohrlen F, Frohme M, Frank U (2004) A fragile X mental retardation-like gene in a cnidarian. Gene 343:231-238
24. Huot ME, Bisson N, Davidovic L, Mazroui R, Labelle Y, Moss T, Khandjian EW (2005) The RNA-binding protein fragile X-related 1 regulates somite formation in Xenopus laevis. Mol Biol Cell 16:4350-4361
25. Irwin SA, Galvez R, Greenough WT (2000) Dendritic spine structural anomalies in fragile-X mental retardation syndrome. Cereb Cortex 10:1038-1044
26. Khandjian EW, Corbin F, Woerly S, Rousseau F (1996) The fragile X mental retardation protein is associated with ribosomes. Nat Genet 12:91-93
27. Khandjian EW, Bardoni B, Corbin F, Sittler A, Giroux S, Heitz D, Tremblay S, Pinset C, Montarras D, Rousseau F et al (1998) Novel isoforms of the fragile X related protein FXR1P are expressed during myogenesis. Hum Mol Genet 7:2121-2128
28. Khandjian EW, Huot ME, Tremblay S, Davidovic L, Mazroui R, Bardoni B (2004) Biochemical evidence for the association of fragile X mental retardation protein with brain polyribosomal ribonucleoparticles. Proc Natl Acad Sci USA 101:13357-13362
29. Khandjian EW, Tournier B, Séguin S, Tremblay S, De Koninck P, Davidovic L (2009) RNA granules: functions within presynaptic terminals and postsynaptic spines. In: Squire L (ed) Encyclopedia of neuroscience, vol 8. Elsevier, London, UK, pp 389-395
30. Kirkpatrick LL, McIlwain KA, Nelson DL (1999) Alternative splicing in the murine and human FXR1 genes. Genomics 59:193-202
31. Klein SL (1987) The first cleavage furrow demarcates the dorsal-ventral axis in Xenopus embryos. Dev Biol 120:299-304
32. Kooy RF (2003) Of mice and the fragile X syndrome. Trends Genet 19:148-154
33. Lim JH, Luo T, Sargent TD, Fallon JR (2005) Developmental expression of Xenopus fragile X mental retardation-1 gene. Int J Dev Biol 49:981-984
34. Mazroui R, Huot ME, Tremblay S, Filion C, Labelle Y, Khandjian EW (2002) Trapping of messenger RNA by fragile X mental retardation protein into cytoplasmic granules induces translation repression. Hum Mol Genet 11:3007-3017
35. Mientjes EJ, Willemsen R, Kirkpatrick LL, Nieuwenhuizen IM, Hoogeveen-Westerveld M, Verweij M, Reis S, Bardoni B, Hoogeveen AT, Oostra BA et al (2004) Fxr1 knockout mice show a striated muscle phenotype: implications for Fxr1p function in vivo. Hum Mol Genet 13:1291-1302
36. Miyashiro KY, Beckel-Mitchener A, Purk TP, Becker KG, Barret T, Liu L, Carbonetto S, Weiler IJ, Greenough WT, Eberwine J (2003) RNA cargoes associating with FMRP reveal deficits in cellular functioning in Fmr1 null mice. Neuron 37:417-431
37. Morris EJ, Fulton AB (1994) Rearrangement of mRNAs for costamere proteins during costamere development in cultured skeletal muscle from chicken. J Cell Sci 107(Pt 3):377-386
38. Nieuwkoop PD, Faber J (1956) Normal table of Xenopus Laevis (Daudin): a systematical & chronological survey of the development from the fertilized egg till the end of metamorphosis. North-Holland Publishing Company, Amsterdam
39. O'Donnell WT, Warren ST (2002) A decade of molecular studies of fragile X syndrome. Annu Rev Neurosci 25:315-338
40. Papoulas O, Monzo KF, Cantin GT, Ruse C, Yates JR 3rd, Ryu YH, Sisson JC (2010) dFMRP and Caprin, translational regulators of synaptic plasticity, control the cell cycle at the Drosophila mid-blastula transition. Development 137:4201-4209
41. Schaeffer C, Bardoni B, Mandel JL, Ehresmann B, Ehresmann C, Moine H (2001) The fragile X mental retardation protein binds specifically to its mRNA via a purine quartet motif. EMBO J 20:4803-4813
42. Stefani G, Fraser CE, Darnell JC, Darnell RB (2004) Fragile X mental retardation protein is associated with translating polyribosomes in neuronal cells. J Neurosci 24:7272-7276
43. Summerton J, Weller D (1997) Morpholino antisense oligomers: design, preparation, and properties. Antisense Nucleic Acid Drug Dev 7:187-195
44. Tucker B, Richards R, LardelliM(2004) Expression of three zebrafish orthologs of human FMR1- related genes and their phylogenetic relationships. Dev Genes Evol 214:567-574
45. Wan L, Dockendorff TC, Jongens TA, Dreyfuss G (2000) Characterization of dFMR1, a Drosophila melanogaster homolog of the fragile X mental retardation protein. Mol Cell Biol 20:8536-8547
46. Weiler IJ, Spangler CC, Klintsova AY, Grossman AW, Kim SH, Bertaina-Anglade V, Khaliq H, de Vries FE, Lambers FA, Hatia F et al (2004) Fragile X mental retardation protein is necessary for neurotransmitter-activated protein translation at synapses. Proc Natl Acad Sci USA 101:17504-17509
47. Zhang Y, O'Connor JP, Siomi MC, Srinivasan S, Dutra A, Nussbaum RL, Dreyfuss G (1995) The fragile X mental retardation syndrome protein interacts with novel homologs FXR1 and FXR2. EMBO J 14:5358-5366