Simian hemorrhagic fever virus infection of rhesus macaques as a model of viral hemorrhagic fever: Clinical characterization and risk factors for severe disease

Virology

Volumn 421, Issue 2, 2011, Pages 129-140

  Johnson, Reed F ^a   Dodd, Lori E ^a   Yellayi, Srikanth ^a   Gu, Wenjuan ^b   Cann, Jennifer A ^a   Jett, Catherine ^a   Bernbaum, John G ^a   Ragland, Dan R ^a   St Claire, Marisa ^a   Byrum, Russell ^a   Paragas, Jason ^a   Blaney, Joseph E ^a   Jahrling, Peter B ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b SAIC FREDERICK INC   (United States)

Author keywords

Animal model; Arterivirus; Coagulopathy; Emerging pathogens; Hemorrhagic disease; Hemorrhagic fever virus; Pathogenesis; Simian hemorrhagic fever virus; Virus

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; CYTOKINE; FIBRIN DEGRADATION PRODUCT; GAMMA INTERFERON; HEMOGLOBIN; INTERLEUKIN 1 RA; INTERLEUKIN 18; INTERLEUKIN 6; INTERLEUKIN 8; MONOCYTE CHEMOTACTIC PROTEIN 1; NEUTRALIZING ANTIBODY; RANTES; UNCLASSIFIED DRUG; VASCULOTROPIN;

ABSCESS; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY TITER; ARTERIVIRUS INFECTION; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BACTEREMIA; BLEEDING; CLINICAL FEATURE; CONTROLLED STUDY; DEHYDRATION; DEPRESSION; DIARRHEA; DISEASE MODEL; DISEASE SEVERITY; DYSPNEA; EDEMA; ENCEPHALITIS; EPISTAXIS; FEMALE; GINGIVA BLEEDING; HEART MUSCLE BLEEDING; HEMATOCRIT; HEMATURIA; HEMOGLOBIN BLOOD LEVEL; HEPATITIS; HISTOPATHOLOGY; INOCULATION; INTERSTITIAL NEPHRITIS; INTERSTITIAL PNEUMONIA; LETHALITY; LEUKOPENIA; LIVER NECROSIS; LYMPHADENOPATHY; LYMPHOCYTOPENIA; LYMPHOID HYPERPLASIA; MACACA; MALE; MELENA; MENINGITIS; MONOCYTOPENIA; MORTALITY; MYELITIS; MYOCARDITIS; NECROTIZING HEPATITIS; NEUTROPENIA; NONHUMAN; PARTIAL THROMBOPLASTIN TIME; PETECHIA; PETECHIAL RASH; PRIORITY JOURNAL; PROTEINURIA; PROTHROMBIN TIME; PYLORIC JUNCTION HEMORRHAGE; RASH; RISK FACTOR; SIMIAN HEMORRHAGIC FEVER VIRUS INFECTION; SPLEEN; SPLENOMEGALY; SURVIVOR; TERMINAL COLON HEMORRHAGE; THROMBOCYTE COUNT; THYMUS; TISSUE DISTRIBUTION; VIRAL HEMORRHAGIC FEVER; VIREMIA; VIRUS LOAD; WEAKNESS; WEIGHT REDUCTION;

ANIMALS; ANTIBODIES, NEUTRALIZING; ANTIBODIES, VIRAL; ARTERIVIRUS; ARTERIVIRUS INFECTIONS; CHEMOKINES; CYTOKINES; DISEASE MODELS, ANIMAL; HEMORRHAGIC FEVERS, VIRAL; IMMUNE TOLERANCE; MACACA MULATTA; RISK FACTORS;

ANIMALIA; ARTERIVIRUS; LASSA VIRUS; MACACA; MACACA MULATTA; PRIMATES; SIMIAN HEMORRHAGIC FEVER VIRUS;

EID: 80355146840     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2011.09.016     Document Type: Article

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